• Title/Summary/Keyword: Trnayl-cypromine

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Biotransformation of benzyle trans-2-phenylcyclopropanecarbamate to tranylcypromine in rats

  • Il, Kang-Gun;Chung, Soon-Young
    • Archives of Pharmacal Research
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    • v.7 no.2
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    • pp.141-143
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    • 1984
  • A metabolic study was performed in order to characterize the in vivo MAO-inhibitory activity of benzyl trans-2-phenylcylopropanecarbamate which was reported to be twice as potent as the tranylcypromine. In the rat urine which was obtained after the administration of the benzyl trans-2-pheny-lcyclopropanecarbamate (40mg/kg) through oral route, a metabolic product, tranylcypromine as well as the intact drug was detected by GC/MS.

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