• 대한소아치과학회지
• /
• 제41권4호
• /
• pp.335-343
• /
• 2014

재생적 근관치료는 치수 괴사를 보이는 미성숙 영구치 치료에 있어서 괴사된 치수를 치유하고 계속되는 치근의 발달을 유도할 수 있다. 그러나 여기에는 몇 가지 단점과 불리한 결과들이 있다. 이 중 재생적 근관치료에 가장 큰 임상적 부작용은 minocycline과 MTA에 의한 변색이다. 본 증례에서는 재생적 근관치료 후에 나타나는 치관 변색을 방지하기 위해 minocycline을 clindamycin으로 대체한 triple antibiotics와 칼슘 지르코늄 알루민산염 시멘트인 Retro MTA를 사용하였다. 치수 괴사된 미성숙 영구치에서 근관 와동 형성 및 근관 세척 후 수정된 triple antibiotics를 적용하고, 혈병 또는 콜라겐 스펀지를 스캐폴드(scaffold)로 하여 Retro MTA로 근관을 폐쇄하였다. 정기적인 검진 결과 미성숙 영구치의 치근 성장 및 정상적인 치아 주위 조직들이 관찰되었으며, 치관 변색 없이 모두 양호한 치유 결과를 얻었다.

• The Korean Journal of Physiology and Pharmacology
• /
• 제27권2호
• /
• pp.157-165
• /
• 2023

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and current therapeutic strategies are limited in their effectiveness. The expressions of Rab5 and the M2 tumor-associated macrophage marker CD163 in tissues were detected by Western blot. The migration and invasion of cells were determined using a Transwell assay. The expressions of the exosome markers were evaluated by Western blot. The polarization of human macrophages (THP-1) was determined by incubation of THP-1 cells with conditioned medium or exosomes collected from MDA-MB-231 cells with indicated transfections or by a coculture system of THP-1 and MDA-MB-231 cells. The M1 and M2 macrophage markers were evaluated by qRT-PCR. The expression of Rab5 in TNBC was significantly higher than that in normal breast tissue. Rab5 expressions in triple-negative and luminal A breast cancer were higher than those in other molecular subtypes. Higher CD163 expression was observed in triple-negative breast cancer and in triple-negative and luminal B subtypes. Rab5 knockdown suppressed but Rab5 overexpression promoted the migration and invasion capacity of MDA-MB-231 cells. The levels of CD63 and CD9 in the medium of Rab5 knockdown cells were lower than those in control cells, whereas higher levels of CD63 and CD9 were observed in Rab5 overexpression cells. Rab5 knockdown decreased the excretion but did not alter the diameter of the exosomes. Knockdown of Rab5 facilitated the anti-tumor polarization of macrophages, which was partially reversed by Rab5 overexpression. Therefore, Rab5 is expected to be a potential therapeutic target for triple-negative breast cancer.

• Journal of electromagnetic engineering and science
• /
• 제17권2호
• /
• pp.86-90
• /
• 2017

In this study, a novel third-order bandpass filter, which is based on a rectangular closed loop resonator, is presented. By adding a series resonator to the conventional loop resonator, the resonator's even resonant mode is split into two modes, while the odd resonant mode is not affected. Therefore, by varying the values of the series resonator elements, the resonant frequencies of two even modes can be determined independent of the odd-mode resonant frequency. In the proposed triple-mode filter design, instead of using a lumped series resonator, a T-shaped transmission line is coupled to the resonator via a small gap. To verify the design method, a filter is designed at 2.4 GHz with a bandwidth of 100 MHz. The improved performances of the proposed triple-mode filter are compared with those of the conventional dual mode filter.

• 대한치과보철학회지
• /
• 제55권4호
• /
• pp.372-380
• /
• 2017

목적: 본 연구는 보철물의 적합도를 계측하는 두 가지의 측정방법을 평가하기 위해 지르코니아로 전부도재관을 제작하고 replica technique과 triple-scan protocol을 이용하여 전부도재관의 변연 및 내면 적합도를 비교 연구하고자 하였다. 재료 및 방법: 타이타늄의 지대치 모형을 제작하여 20개의 지르코니아 전부도재관을 제작하였다. 제작된 지르코니아 전부도재관 10개는 replica technique을 이용해 복제하고 복제된 시편을 협설, 근원심으로 절단하여 변연 및 내면 적합도를 측정하였고, 다른 10개의 전부도재관은 triple-scan protocol을 이용하여 협설과 근원심으로 단면을 형성하고 변연 및 내면 적합도를 계측하여 통계 분석하였다 (${\alpha}=.05$). 결과: 변연과 내면 적합도는 replica technique $49.86{\pm}29.69{\mu}m$, triple-scan protocol $75.35{\pm}64.73{\mu}m$로 유의한 차이가 있었고 (P < .001), 내면 적합도만을 측정한 결과 각각 $58.38{\pm}31.77{\mu}m$, $64.00{\pm}46.43{\mu}m$로 유의한 차이가 없었다 (P > .343). 결론: Replica technique과 triple-scan protocol을 이용하여 전부도재관의 변연 및 내면 적합도를 비교 측정한 결과 triple-scan protocol에서의 변연 적합도가 크게 측정되었고, 내면 적합도만 비교해 본 결과 통계적인 유의한 차이가 없었다.

• Asian Journal of Business Environment
• /
• 제2권2호
• /
• pp.35-39
• /
• 2012

Purpose - Today's world is rapidly changing due to swift changes in organization's infrastructures and supply chain is becoming an important factor which affects the organization's global competitiveness. Research design / data / methodology - Researchers indicated that environment uncertainty is considered an external driving force to establish a unique supply chain. Market competition, reducing the gap of performance and quality between the products are compelling the practitioners and researcher to change the paradigm of managing the business processes effectively and efficiently. Results - In old times, supply chain of any organization was measured on the basis of inventory turns, defect rats, lead times, stock buffering and service level. But, Lee H.L. in 2004, published an article in Harvard Business Review who proposed three A (Adaptable, Agile and Aligned) termed as "Triple-A" of successful supply chain. Conclusions - He claimed that organizations can compete through the creation of Triple-A supply chain. Hence, the basic aim of this review paper is to develop basic insights regarding what is Triple-A of supply chain, its importance and functioning in today's competitive world.

• Nuclear Engineering and Technology
• /
• 제52권9호
• /
• pp.2138-2150
• /
• 2020

We report the status of the cold neutron triple-axis spectrometer (Cold TAS) and thermal neutron triple-axis spectrometer (Thermal TAS) installed at HANARO. Cold TAS, whose specifications are standard across the world, is in the final phase of commissioning. Proper instrument operation was confirmed through a feasibility study of phonon measurements and data analyses with resolution convolution. In contrast, Thermal TAS is in the initial phase of commissioning, and improvement of the monochromator drum is now in progress from the viewpoint of radiation shielding. In addition, we report recent activities in the development of neutron basic elements, that is, film-coated Si-wafer collimators, which are promising for use in triple-axis spectroscopy, particularly in Cold TAS.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제3권2호
• /
• pp.188-194
• /
• 2000

반복되는 구토로 인한 폐렴 증세로 내원하여 분문무이완증, 무루증, 신경인성방광 등의 소견을 보여 Triple A 증후군으로 진단받고, 식도하부 괄약근의 반복 확장술(pneumatic dilatation)로 증상이 소실된 환아 1례를 경험하였기에 이에 보고하는 바이다.

• Journal of Biosystems Engineering
• /
• 제29권3호
• /
• pp.281-286
• /
• 2004

The end-effector is the one of the important factors on development of the cucumber robot to harvester a cucumber. Three end-effectors were designed the single blade end-effector with one blade, the double blade end-effector with two blades and the triple blade end-effector with three blades. Performance tests of the end-effector, the fully integrated system, were conducted to determine the cutting rate by using two different kinds of cucumber. The success rates of cucumber cutting ratio of single end-effector, double end-effector and triple end-effector in laboratory. were 61.7%, 95%, 86.7%, respectively. The cutting rate of single blade or double blade was a little difference with respect to the different diameters of cucumber stem. However, the success cutting rate of the end-effector with triple blade was 61.7% under 29mm diameter of a grabbing stem section. The triple end-effector was not suitable for harvesting a cucumber, but was considered to be suitable for harvesting a grape, an apple and a tomato. The success rate of cucumber cutting ratio of triple end-effectors in greenhouse was 84%. The failure cutting rate was 16% which are due to abnormal shape of cucumber fruit.

• Clinics in Shoulder and Elbow
• /
• 제12권1호
• /
• pp.80-83
• /
• 2009

목적: 삼중 관절와 순 병변(triple labral lesion)은 전방, 후방, 상방 관절와 순의 파열이 동시에 발생한 경우를 말한다. 문헌 보고가 드물어서, 수상 기전과 증상에 대하여 아직 정립되지는 않았다. 대상 및 방법: 본 저자들은, 교통 사고 후 우측 견관절의 동통과 능동적 외전 장애를 보인 39세 남자에서 삼중 관절와 순 병변을 경험하였다. 내원 시에 관절와 상완 관절의 불안정에 대한 증상을 호소하지는 않았다. 흡수성 봉합 나사못과 봉합 갈고리를 사용하여 관절와 순에 대한 봉합술을 시행하였다. 결과: 수술 후 18개월 추시에서, 능동적 운동범위는 정상으로 호전되었으며 일상 생활 중에는 어려움이 없었다.

• Journal of information and communication convergence engineering
• /
• 제13권3호
• /
• pp.159-166
• /
• 2015

In this paper, a novel design for a triple-band coplanar waveguide (CPW)-fed monopole antenna for WLAN/WiMAX operations is proposed. The proposed antenna is printed on an FR4 substrate with an area of 22.0 mm × 30.0 mm, a thickness of 1.0 mm, and a relative permittivity of 4.4. The effects of various parameters of the proposed for triple band operation is investigated. Two half circular rings and a microstrip feed line are fabricated on the substrate to achieve triple band operation and good impedance matching. Prototypes of the proposed antenna have been fabricated and tested. Experiment results reveal that the measured return loss exhibits an acceptable agreement with the simulated return loss and satisfies the impedance bandwidth requirement of -10 dB, while simultaneously covering the WLAN and WiMAX bands. In addition, the proposed antenna shows good radiation characteristics and gains in the three operating bands.