• Title/Summary/Keyword: Triglycerides

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The Effects of Wolbiga-banha-tang on Obese Rats Fed a High-fat Diet (월비가반하탕이 고지방식이로 유도된 비만 쥐에 미치는 영향)

  • Na, Ga-young;Moon, Young-ho;Lee, Hye-in;Kim, Eun-ji
    • The Journal of Internal Korean Medicine
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    • v.37 no.6
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    • pp.1012-1021
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    • 2016
  • This study investigated the effects of Wolbiga-banha-tang (WBBT) on high fat diet-induced rats. We divided the rats into 4 groups: normal (fed a general-fat diet), control (fed a high-fat diet and no treatment), $WBBT{\times}1$ (fed a high-fat diet and 250 mg/kg of Wolbiga-banha-tang extracts), and $WBBT{\times}2$ (fed a high-fat diet and 500 mg/kg of Wolbiga-banha-tang extracts). We measured the body weight, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, free fatty acids, total lipids, AST, ALT, and CBC in the serum of the obese rats for 7 weeks. There was a significant decrease in the control group, $WBBT{\times}1$, and $WBBT{\times}2$ in triglycerides and free fatty acids. The results suggest that WBBT is effective for lowering triglycerides and free fatty acids. Therefore, WBBT may be applied to the treatment of lipid metabolism in obesity and further clinical studies are needed.

Wax Gourd Reduces Adipose Depots and Fat Cell Sizes without Affecting the Levels of Leptin in Rats Fed Medium Fat

  • Kang Keum-Jee
    • Nutritional Sciences
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    • v.9 no.3
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    • pp.173-178
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    • 2006
  • The purpose of this study was to investigate the effects of wax gourd on body weight, body fat, triglyceride, leptin and fat cell size in rats fed medium fat Male Sprague Dawley rats were fed with experimental diet containing total dietary fat at 20% of calorie with wax gourd (WG) for 4 weeks. Forty rats were divided into 4 groups including control, 5, 10, and 15% (w/w) WG supplement The results showed that weight gain was significantly higher in 5% WG than that in control (p<0.05), but was not different among the WG supplement groups. Total fat weight was significantly decreased in both 10 and 15% WG supplement groups than that of control. The levels of triglycerides and free fatty acids in the plasma were significantly decreased, particularly in 15% WG supplement group (p<0.05). The levels of leptin was not significantly different among the experimental groups. Fat cell size was significantly decreased in WG supplement groups compared to that of control group (p<0.05). Correlation among the parameters demonstrated that weight gain correlated positively with total fat weight, the levels of leptin and triglycerides. Taken these results together, 15% WG supplement diet substantially reduces total fat weight, triglycerides and free fatty acids levels and fat cell size in the rat fed midium fat.

Relationship between Serum Uric Acid, Abdominal Obesity, and Waist Circumference in Korean

  • Park, Kap-Tae;Kim, In-Sik;Yoo, Se-Cheol;Yoon, Jin-Seok;Ahn, Tae-Ho;Lee, Jung-Hwa;Hyun, Sung-Hee
    • Korean Journal of Clinical Laboratory Science
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    • v.44 no.2
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    • pp.39-45
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    • 2012
  • The purpose of this study was to determine the association between serum uric acid, abdominal obesity, and waist circumference (WC) in Korean. A total of 208 healthy examinees were examined at Gimcheon Medical Center from July 2011 to December 2011. WC and body mass index (BMI) of subjects were measured as well as blood pressure, fasting blood sugar level, High Density Lipoprotein (HDL) and Low Density Lipoprotein (LDL) cholesterol, C-reactive protein (CRP), triglycerides, and serum uric acid (SUA). In both men (p<0.05) and women (p<0.01), BMI and SUA were significantly correlated with WC. In men, triglycerides (r=0.501, p<0.01) had a positive correlation with WC, and CRP (r=0.442, p<0.01) had a positive correlation with BMI. In women, triglycerides (r=0.470, p<0.01) and CRP (r=0.366, p<0.01) had a positive correlation with WC. Therefore, WC and SUA may be the most effective anthropometric indices of obesity for screening Korean population.

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The Affecting Factors of Metabolic Syndrome in Korean Adults in Their 30s and 40s (삼사십대 성인에서 대사증후군 관련 영향 요인)

  • Lee, Hyun-Mee;Kam, Sin;Jin, Soo-Hee
    • The Korean Journal of Health Service Management
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    • v.12 no.3
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    • pp.143-156
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    • 2018
  • Objectives: The aim of this study was to determine the affecting factors of metabolic syndrome (MetS) and it's components in Korean adults in their 30s and 40s. Methods: The present study assessed 1,215 subjects who participated in the Korea National Health and Nutrition Examination Survey in 2014. We analyzed the prevalence rate of MetS and it's components and their affecting factors. Results: The prevalence rate of MetS was 16%. Family history of diabetes mellitus and, low or high saturated fat intake were associated with MetS in males. Low income, low education, excessive sleep, excessive carbohydrate and low saturated fat intake were associated with MetS in females. Triglycerides showed the highest prevalence in males and were related to white collar socioeconomic status, smoking, and obesity. Triglycerides and high-density lipoprotein cholesterol were high in females, and triglycerides were affected by excessive sleep, family history, low saturated fat intake, and obesity. High-density lipoprotein cholesterol was affected by obesity. Conclusions: Because sex differences exist in MetS, it is necessary to intervene through diverse approaches. In particular, a continuous management and preventive intervention for obesity is needed.

Factors related to undiagnosed diabetes in Korean adults: a secondary data analysis (한국 성인의 당뇨병 미진단 비율 영향요인: 2차 자료 분석 연구)

  • Bohyun Kim
    • Journal of Korean Biological Nursing Science
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    • v.25 no.4
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    • pp.295-305
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    • 2023
  • Purpose: This study compared health behaviors and health-related clinical characteristics between individuals with normal glucose levels without diabetes and those with undiagnosed diabetes. Factors that were associated with undiagnosed diabetes were identified by sex. Methods: This was an observational study with a cross-sectional design based on data from the eighth Korea National Health and Nutrition Examination Survey, which used a stratified, multi-stage, cluster-sampling design to obtain a nationally representative sample. Multiple logistic regression analysis was employed to compute the odds ratios of health behaviors and clinical characteristics to identify risk factors for undiagnosed diabetes. Results: The overall prevalence of undiagnosed diabetes was 5.2% (weighted %, n = 700, p < .001). Among individuals with undiagnosed diabetes, 58.3% were men. Univariate logistic regression for undiagnosed diabetes identified sex, age, house income, educational level, and triglycerides as influencing factors. In multiple logistic regression by sex, the factors associated with undiagnosed diabetes in men were age, perceived health status, a diagnosis of angina, and triglycerides. Conclusion: Strategies should be targeted to improve health behaviors and clinical characteristics for specific age groups, men in bad perceived health status, women with high systolic blood pressure, and high triglycerides. Moreover, healthcare providers should understand the barriers to health behaviors and health-related quality of life to effectively deliver healthcare services.

Changes in Total Fatty Acids, Total Number of Fatty Acid Acyl Carbon Atoms and Species of Triglycerides from Human Milk Lipids during the Course of Lactation (수유 기간의 경과에 따른 인유 트리글리세리드의 지방산 조성, 아실 탄소수 및 종의 변화)

  • Yoon, Tai-Heon;Im, Kyung-Ja
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.14 no.1
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    • pp.39-46
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    • 1985
  • The fatty acid composition, total number of fatty acid acyl carbon atoms and species of triglycerides from human milk samples obtained during 70 days of lactation from 39 mothers were determined by argentation thin-layer and gas chromatographic procedures. The medium- and long-chain saturated fatty acids(8:0, 1O:0, 12:0 and 14:0) which are formed exclusively by synthesis within mammary gland increased significantly from colostrum to mature milk. Long-chain saturated fatty acids(16 : 0, 22 : 0 and 24: 0) were significantly higher than tile levels found in transitional and mature milk. The precursors of w C- and w 3-series, 18:2 w 6 and 18:3 w 3, were increased slightly in progressing lactation. Colostrum contained significantly higher proportions of 18:1 w 9 and w 6- and w 3- derived long-chain polyunsaturated fatty acids than transitional milk, and these levels were further reduced in mature milk. The triglycerides of human milk lipids which were made up of 30-60 acyl carbon atoms showed a pattern with major contributions made by the glycerides with 44-52 acyl carbon atoms. The levels of triglycerides with less than 46 acyl carbon atoms increased significantly with the elapse of lactation period, whereas those with more than 50 acyl carbon atoms decreased significantly. The fully saturated trig1ycerides increased significantly as the lactation proceeded, but the dienoic triglycerides declined significantly.

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Studies on Genetics and Breeding of Rainbow Trout(Oncorhynchus mykiss) II. Relationships between Levels of Serum LH, FSH and Estradiol-$17{\beta}$ ; and Levels of Albumin, Total Protein, and Triglycerides ; and their Effect on the Changes of Gonadosomatic Indices in the Ovarian Development in the Rainbow Trout (무지개송어의 유전 육종학적 연구 II. 무지개송어의 난소 발달에 영향을 미치는 혈청중 LH, FSH, Estradiol-$17{\beta}$ 수준과 Albumin, Total Protein, Triglycerides 함량과의 관계 및 성선지수 변화간의 상관관계)

  • Yoon Jong-Man;KIM Gye-Yoong;PARK Hong-Yang
    • Journal of Aquaculture
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    • v.4 no.2
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    • pp.97-110
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    • 1991
  • This study was undertaken to understand the seasonal changes of hormone levels such as luteinizing hormone (LH), follicle stimulating hormone (FSH) and estradiol-$17{\beta}$, serum components such as albumin, total protein and triglycerides, and GSI of rainbow trout (Onco-rhynchus mykiss) under the normal-light circumstances. LH levels were the highest in November whereas FSH levels were decreased progressively from October to February. Serum GTH, such as LH and FSH, levels were low immediately after egg-stripping and were significantly increased in the summer in association with the initiation of vitellogenesis. Serum albumin, total protein, and triglycerides were significantly increased in August in association with initiation of vitellogenesis and were peak in November prior to egg-stripping. Oocyte growth, measured by oocyte diameter and GSI, was significantly increased in August and showed the highest value in January. Correlation coefficients of serum LH with FSH and estradiol-$17{\beta}$ were +0.844 and +0.947, respectively. Correlation coefficients of estradiol-$17{\beta}$ with albumin and total protein were +0.634 and +0.859, respectively. Correlation coefficients of serum estradiol-$17{\beta}$ with triglycerides and GSI were +0.673 and +0.694, respectively. Probably by positive feedback mechanism, LH, FSH and estradiol-$17{\beta}$ appeared to stimulate to liver to secrete albumin, total protein and triglycerides for vitellosenesis.

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Effects of Ginseng on the Blood Biochemical Components of Heavy Metals Poisoning (중금속 중독시 인삼이 혈액성분에 미치는 영향)

  • 김종오;박귀례
    • Journal of Food Hygiene and Safety
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    • v.2 no.4
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    • pp.201-208
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    • 1987
  • The effects of ginseng on the blood biochemical components of heavy metals poisoning in mice were examined and following results were obtained. Albumin was decreased slightly in the heavy metal administration groups. But Serum Calcium, Glucose were almost the same as that of control group during the period. Heavy metal poisoning mice showed low levels of serum Total protein and A/G ratio. They also showed high levels of serum GOT, GPT, BUN, Cholesterol, Creatinine and Triglycerides. However, the administration of ginseng significantly inhibited the elevation of them.

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Molecular Species of Triglycerides in Safflower Oil (홍화유의 triglyceride 분자종에 관한 연구)

  • Cheon, Seok-Jo;Park, Yeung-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.16 no.4
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    • pp.337-342
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    • 1987
  • Triglyceride molecular species of safflower oil was examined from the profiles of triglyceride composition and the fatty acid at ${\beta}-position$ of glycerol. From the results, triglycerides were found to be 26kinds in safflower oil. The major triglyceride molecular species in safflower oil were identified to be PLL; 10,4%, OLL; 22.3%, LLL; 31.95%. Triglyceride molecular species of safflower oil characterized that species occupied by unsaturated fatty acids at ${\beta}-position$ were more than 90%.

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Fatty Acid Analysis from Leech Skin

  • Hong, Suk-Jin;Kim, Dong-Ryeong;Yoon, In-Joong;Kang, Ke-Won
    • BMB Reports
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    • v.28 no.3
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    • pp.261-264
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    • 1995
  • The lipids of a Korean native blood-sucking leech (Hirudo nipponia) were isolated and analyzed. Cholesterol, fatty acids, triglycerides, glycerylether diester and cholesteryl esters were found from epidennal extracts. The major fatty acids in the leech skin were $C_{16:0}$, $C_{18:0}$, $C_{20:1}$. $C_{20:3}$ components. These components were derived from cholesteryl esters, glycerides, fatty acids and other polar lipids. After 60 days fasting, cholesterol, fatty acids and triglycerides in the skin were reduced in number and the total fatty acid composition was changed slightly. The data of total fatty acids in fasted and fed leech showed that medium-chain fatty acids were more affected than long-chain fatty acids. Other trace fatty acids appeared to be decreased by fasting.

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