• Title/Summary/Keyword: Treatment Period

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구상흑연주철의 Bainite변태과정에서 Bainitic Ferrite의 형상변화 (Morphological Variation of Bainitic Ferrite in Transformation Process of Austempered Ductile Iron)

  • 최답천
    • 한국주조공학회지
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    • 제12권5호
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    • pp.403-411
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    • 1992
  • The growth characteristics of bainite at early stage in the fast quenched spheroidal graphite cast irons containing 0.06%Mn and 0.45%Mn during austempering process, was investigated with optical and scanning electron microscope. The following results regarding the effects of Mn and isothermal heat treatment on the morphological variation of bainitic ferrite were obtained. The morphology of bainite varies from acicular below 350$^{\circ}C$ to feather shape above 350$^{\circ}C$. The period of isothermal treatment also affects the shape of bainite at the fixed temperature. At 350$^{\circ}C$, bainite is bamboo leaf-like up to 200 secs of isothermal holding time and with further increasing time up to 300 secs, changes to a mixed structure consisting of both feather and bamboo leaf and, finally becomes all feather shape at 900 secs. The morphology of bainitic ferrite formed at early stage of 300$^{\circ}C$ isothermal treatment is similar to that of bainitic ferrite formed at 250$^{\circ}C$ or 350$^{\circ}C$ with unbranched, linear ferrite. However, bainitic ferrite divides into branches with increasing isothermal treatment, which occurs more fast at 400$^{\circ}C$ than at 350$^{\circ}C$. The difference in adding amount of Mn influences the morphology of bainitic ferrite in upper bainite. The bainitic ferrite with 0.45%Mn is observed to be more stable than that with 0.06%Mn, remaining unbranched for a longer period at the same temperature.

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곽향정기산가미방(藿香正氣散加味方) 투여 및 소장정격(小腸正格) 시술을 이용한 편평사마귀의 치료 효과 (Combination Therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok for the Treatment of Verruca Plana)

  • 윤정민;신상호;윤화정;고우신
    • 한방안이비인후피부과학회지
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    • 제23권1호
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    • pp.169-181
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    • 2010
  • Objective : The purpose of this study was to investigate the effects of Combination therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok on patients with verucca plana. Methods : Sixty-five patients(male 19, female 46) with verruca plana were treated with Gwakhyangjeonggisangamibang and Sojangjeonggyeok for at least 3 months. After treatment, a clearance rate was divided into 4 scales such as; complete clearance / partial clearance-good / partial clearance-poor / no change. Statistical analysis was performed by using Independent-sample t-test. Results : Mean age of patients was 30.3 and mean period of disease duration was 64.6 months. Fifty-eight patients(73.8%) showed complete clearance, nine(13.8%) partial clearance-good, and eight(12.3%) partial clearance-poor. Complete clearance group(CC group) was statistically younger than failure group and disease duration of CC group was shorter than failure group. Although treatment period of failure group was statistically longer than CC group and dosage(貼) of herbal medicine of failure group was more than CC group, failure group showed partial clearance. Conclusion : This data demonstrates that combination therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok could be an effective and safe treatment for the verucca plana.

Notification of Terminal Status and Advance Care Planning in Patients with Cancer

  • Lee, Si Won
    • Journal of Hospice and Palliative Care
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    • 제25권1호
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    • pp.42-49
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    • 2022
  • As population aging increases the burden of cancer, the quality of death of patients with cancer is emerging as an important issue alongside their quality of life. To improve the quality of death, it is necessary to prepare for death, allowing patients to die comfortably and with dignity at the end. Considering these issues, I aim to discuss the practical aspects of notifying the patient of the terminal phase of cancer and planning for end-of-life care (i.e., advance care planning). When cancer treatment that can extend the patent's lifespan becomes difficult, the patient enters a treatment transition period. Treatment is shifted from life-prolonging care to life-enhancing care, and end-of-life care must be well planned. Medical providers often worry too much about whether the patient will be disappointed or psychologically traumatized when notified of the terminal phase of their cancer, thus delaying plans for end-of-life care. In fact, patients can accept their condition and prepare for end-of-life care better than we expect. During the treatment transition period, notification of terminal status should be given, and a well-prepared advance care plan should be established early when the patient has decision-making ability. In addition to conveying information, it is always necessary to be sensitive to whether the patient and caregiver understand the information and respond to their emotions.

예건 및 첨가제가 호밀사일리지의 발효특성과 사료가치 및 호기적 안정성에 미치는 영향 (Effects of Wilting and Additives on the Fermentation Chrateristics , Quality and Aerobic Stability of Rye Silage)

  • 이광녕;김동암
    • 한국초지조사료학회지
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    • 제17권2호
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    • pp.187-198
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    • 1997
  • This experiment was conducted to evaluate effects of wilting and additives on fermetation characteristics, quality and aerobic stability of silage of rye(Seca1e cereale L.) harvested at the early heading stage. Harvested rye was wilted or mixed with beet pulp and then treated with formic acid or lactic acid bacteria(LAB) inoculant. Treatments were consisted of direct cut(DC), wilted(WT), beet pulp added(BP), direct cut and formate applied(DF), wilted and formate applied(WF), beet pulp and formate applied(BF), direct cut and LAB inoculated(DL), beet pulp added and LAB inoculated(BL), and wilted and LAB inoculated(WL) silages. Afler 70 days of ensiling period, the silages were opened and exposed to air for 7 days, and the silages of opening day(0 day) were compared with the silages exposed to air for 7 days(7 day). 1. LAB inoculated rye silages(DL, WL, BL) lowered pH values effectively eom the third day of ensiling and showed most stable pattern of pH changes during the initial fermentation process. Direct cut and formate applied(DF), beet pulp and formate applied(BF) and beet pulp added(BP) silages were also effective in lowering pH from the seventh day thai direct cut treatment(DC). 2. pH was low below 3.7 in all treatments of 0 day. After 7-day period of aerobic exposure, DL and WL showed considerable increases in pH from 3.5 and 3.4 to 8.3 and 6.4, respectively. 3. Direct cut rye silages(DF, DC, DL) and beet pulp and formate treatment(BF) produced effluent of 121.2, 85.9, 80.3 and 34.2 mlkg, respectively and these were greater than others(P<0.01). Beet pulp retained 1.61 I/kg of effluent at the application rate of 50 kg/t in comparing BP with DC, and formate application increased the amount of effluent in comparing DF and BF with DC and BP, respectively(P<0.01). 4. Beet pulp and LAB treatment(B1) was highest in content of lactate as 3.1% and formate treated silages(DF, WF, BF) showed lower content of lactate and total acid than others. LAB inoculated(D1, WL, BL) and wilted (WT) silages were graded to be good quality as a second group by the Flieg's score. Formate applied silages (DF, WF, BF) were graded as a foum group lower than DC by one. 5. Residual content of WSC of rye silage was higher in BP, BF, DL and BL than direct cut treatment(M3) (P< 0.01). Formate application had a tendency to increase the content of residual content of WSC. 6. For the ratio of NH3-N to Total N, wilted and LAB inoculated(W1) and direct cut and LAB inoculated(D1) silages were lowest on 0 day as 8.9 and 9.3% respectively. But after 7-day period of aerobic exposure, WL and DL showed largest increase of the ratio of $NH_3-N$ to Total N from 0 day(P<0.01). 7. On 0 day wilted(WT), beet pulp and formate treatment(BF), and beet pulp and LAB treatment(B1) were lower than direct cut treatment(DC) for NDF and ADF concentrations consistently. Formate applied silages (DF, WF, BF) made little change in ADF and NDF concentrations during 7 day period of aerobic exposure. DL and WL showed a large increase in ADF and NDF concentrations under aerobic condition(P<0.01). 8. IVDMD values of wilted(WT), beet pulp added(BP), wilted and LAB inoculated(W1) and beet pulp added and LAB inoculated(B1) silages were higher than direct-cut treatmentPC) as 84.7, 84.7, 84.4 and 83.0%, respectively on 0 day. But during 7-day period of aerobic exposure, a great decreae in IVDMD of WL was showed(P<0.01). The experimental results indicate that wilted silage(WT) could be recommended as the most effective treatment for reducing efluent and increasing quality and feed value of rye silage without deteriorating aerobic stability more than direct cut treatment(DC). Additionally, under unfavorable weather condition beet pulp added and LAB inoculated treatment(T3L) might be the possible alternative for successful ensiling of forage rye.

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심미치료를 위한 전치부 부분교정 (Anterior teeth alignment for aesthetic dentistry)

  • 박철완
    • 대한치과의사협회지
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    • 제56권9호
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    • pp.512-520
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    • 2018
  • As the demand for natural and beautiful smiles increases, the demand for anterior aesthetic treatment is increasing. Orthodontic treatment is often necessary for esthetic, healthy and natural treatment outcome. Particularly, in the case of middle-aged patients, minor tooth movement limited to anterior teeth is more effective than comprehensive orthodontic treatment which requires a long-term treatment period. Clinician who is in charge of aesthetic dentistry should have the ability to select a case that can be treated with partial orthodontic treatment and to determine the most effective treatment method. This article provides decision flowchart for case selection and choosing the best treatment modality for anterior teeth alignment.

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鼻茸(Nasal Polyp)에 對한 文獻的 考察 (A Literature study on the Nasal Polyps)

  • 김현아
    • 한방안이비인후피부과학회지
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    • 제12권1호
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    • pp.338-355
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    • 1999
  • In the treatment of Nasal Polyps. which are produced with allergic rhinitis, chronic paranasal sinusitis at clinic. Herb-med., acupuncture and some medicine for external application have been used. The symptoms, however, has taken a turn for the better in temporary, the nasal polyps was not removed in completely. So the origin treatment was impossible by the use of herb-med.. acupuncture and medicine. Although a surgical operation (excision) of western-medicine is effective for a specified period of time (about 6 months), the nasal polyps tend to recur. Because of that the second and third operation might be needed, so we cannot consider the operation as the treatment of nasal polyps. The study was observed to investigate the nasal polyps treatment, and to search practical attempt for the clinic application through a literature study on Bisikyuk and Bithch which are similar with nasal polyps. As results, the practical application of external treatment for the nasal polyps treatment in clinic might be more necessary, and internal use of the Herb-med. with the external treatment might be treated as supplementary treatment.

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죽초액을 급여한 육용 오리고기의 저장기간 중 pH, 지방산패도, 육색 및 관능평가의 변화 (Changes of pH TBA, Meat Color and Sensory Evaluation on Duck Meat Fed Supplemental Bamboo Vinegar during Storage Period at 4$^{\circ}C$)

  • 국길;김광현
    • 한국가금학회지
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    • 제29권4호
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    • pp.287-292
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    • 2002
  • This study was conducted to investigate the changes of pH, TBA, meat color and sensory evaluation on duck meat fed supplemental Bamboo vinegar during storage period at 4$^{\circ}C$ . Experiment animals (five-wk-old, Cherry Valley F$_1$, 100 chicks) were randomly assigned in four treatment groups. Treatments were control, 1%, 2% and 4% based on Bamboo vinegar addition. There was no PH difference in breast meat between groups on day 1 of storage, while pH of bamboo vinegar supplemented group was sustained hi호 after 3 days. TBA values of Bamboo vinegar treated groups were significantly lower than control group (P<0.05) and were steady change during storage. The color value in lightness no difference between groups during the storage. The control was significantly increased in 6 d and 9 d, while the bamboo vinegar treated groups no difference during storage. The redness and yellowness in bamboo vinegar treatment were decreased in 3 d and 9 d storage. The decrease in yellowness was outstandingly observed in bamboo vinegar 1% and 2% treatment (P<0.05). The odor in terms of sensory evaluation was improved by supplemental bamboo vinegar treatment. The significant differences were observed on 1 d, 3 d and 6 d storage (P<0.05). The appearance of sensory evaluation of supplemental Bamboo vinegar treated groups (P<0.05) was significantly different in 1 d and 3 d storage. The results of this study indicate that the supplemental Bamboo vinegar 1% and 2% may improve meat quality during storage period in duck meat.

고수부지활용 수질정화 자유수면 인공습지의 초기처리수준 (Treatment Efficiency of a Surface - Flow Wetland System Constructed on Floodplain)

  • 양홍모
    • 한국환경농학회지
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    • 제20권4호
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    • pp.277-283
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    • 2001
  • This paper presents treatment efficiency and plant growth of a surface-flow constructed wetland system (30 meter in length and 10 meter in width) over one year after its establishment on a floodplain of a stream. Cattails (Typha angustiflora) grown on pots were transplanted on one half of its area from inlets and reeds (Phragmites australis) on another half from an outlet. Effluent discharged from a secondary-level treatment plant was funneled into the system. The stems of cattails and reeds emerging in April 2001 grew up to 165.9 cm and 95.3 cm, respectively until July 2001. The number of stems of cattails arid reeds in July 2001 increased by 65% and 100%, respectively, compared with that just after their planting. The growth of cattails was better than that of reeds during study period. The removal rates for SS, $BOD_5$, T-N and T-P was 33%, 43%, 31%, and 51%, respectively. The system was inundated seven times by storms over the monitoring period, which disturbed its environment and led to its lower treatment rates. The increase of SS concentration in effluent after inundation of the system was attributed to the falls of soil particles onto its water surface, which had been attached to the emergent plants by floods. Purification rates for T-N were relatively low for the period of late fall through winter until early spring due to lower water temperature which may have retarded microbial nitrification and denitrification mechanisms. Reduction in T-P concentration during fall and winter was relatively higher than that during summer and spring, which may have resulted from no system perturbations by floods and heavy storms during fall and winter.

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Neuroprotective Effects by Nimodipine Treatment in the Experimental Global Ischemic Rat Model: Real Time Estimation of Glutamate

  • Choi, Seok-Keun;Lee, Gi-Ja;Choi, Sam-Jin;Kim, Youn-Jung;Park, Hun-Kuk;Park, Bong-Jin
    • Journal of Korean Neurosurgical Society
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    • 제49권1호
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    • pp.1-7
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    • 2011
  • Objective: Glutamate is a key excitatory neurotransmitter in the brain, and its excessive release plays a key role in the development of neuronal injury. In order to define the effect of nimodipine on glutamate release, we monitored extracellular glutamate release in real-time in a global ischemia rat model with eleven vessel occlusion. Methods: Twelve rats were randomly divided into two groups: the ischemia group and the nimodipine treatment group. The changes of extracellular glutamate level were measured using microdialysis amperometric biosensor, in coincident with cerebral blood flow (CBF) and electroencephalogram. Nimodipine (0.025 ${\mu}g$/100 gm/min) was infused into lateral to the CBF probe, during the ischemic period. Also, we performed Nissl staining method to assess the neuroprotective effect of nimodipine. Results: During the ischemic period, the mean maximum change in glutamate concentration was $133.22{\pm}2.57\;{\mu}M$ in the ischemia group and $75.42{\pm}4.22\;{\mu}M$ (p<0.001) in the group treated with nimodipine. The total amount of glutamate released was significantly different (P<0.001) between groups during the ischemic period. The %cell viability in hippocampus was $47.50{\pm}5.64$ (p<0.005) in ischemia group, compared with sham group. But, the %cell viability in nimodipine treatment group was $95.46{\pm}6.60$ in hippocampus (p<0.005). Conclusion: From the real-time monitoring and Nissl staining results, we suggest that the nimodipine treatment is responsible for the protection of the neuronal cell death through the suppression of extracellular glutamate release in the 11-VO global ischemia model of rat.