• Title/Summary/Keyword: Treatment Efficacy

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The effects of C. annuum L. var. angulosum Mill on cancer cell lines and each organ of the mouse

  • Chung, Yong-Za;Lee, Jeong-Hee
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.152.1-152.1
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    • 2003
  • Under the vigorous search for active novel agents for cancer prevention and treatment, some agents have been found from plants and animals which are easily available. Our review of literature on them revealed that C. annuum L. var. angulosum Mill had high antiproliferating effect on cancer cells. Thus we investigated the efficacy of C. annuum L. var. angulosum Mill on cancer cell lines and to examined its effect on the mouse to detect other side effect and mechnism by which the extrat of C. annuum L. var. angulosum Mill had the anti-cancer efficacy on cancer. (omitted)

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Effect of Asthma Management Educational Program on The Disease Related Knowledge, Stress, and Self-efficacy of Asthmatics Allergic to House Dust Mite (천식관리 교육 프로그램이 집먼지 진드기 알레르기성 천식환자의 질병관련 지식, 스트레스 및 자기효능감에 미치는 효과)

  • Yoo, Yang-Sook;Cho, Ok-Hee;Jung, Hae-Sun
    • Korean Journal of Adult Nursing
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    • v.16 no.4
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    • pp.617-625
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    • 2004
  • Purpose: The purpose of this study was to investigate the effect of the asthma management educational program given to the allergic asthmatics receiving immunotherapy due to house dust mite on the disease related to knowledge, stress, and self-efficacy. Method: The subjects of this study were the patients received immunotherapy to house dust mite at a week interval after being diagnosed for house dust mite allergic asthma at the respiratory center of a hospital affiliated to the university. They were divided into the experimental group of 29 patients who received asthma management education, the control group of 32 patients, and 61 patients in total. Experimental treatment, as an asthma management educational program, was the group education of one time and the reinforcement education of three times with environmental therapy and immunotherapy to house dust mite. Results: The results revealed that the improvement in disease related knowledge, the improvement in self-efficacy and the decrease in stress, were significantly higher in the experimental group than the control group. Conclusions: The asthma management educational program had an effect on improving the disease related knowledge and self-efficacy, and decreasing the stress of the patients asthmatics allergic to house dust mite.

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Effects of Constraint-Induced Movement Using Self-Efficacy Enhancing Strategies on the Upper Extremity Function of Chronic Hemiplegic Patients (자기효능증진전략을 이용한 건측억제유도운동이 편마비 환자의 상지기능에 미치는 효과)

  • Kang, Ji-Yeon
    • Journal of Korean Academy of Nursing
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    • v.36 no.2
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    • pp.403-414
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    • 2006
  • Purpose: The purpose of this study was to investigate the effects of constraint-induced (CI) movement using self-efficacy on U/E function of chronic hemiplegic patients. CI movement discourages the use of the unaffected U/E, combined with intensive training of the affected U/E. Method: A non-equivalent pretest-posttest design was used. Study subjects were 40 hemiplegic patients conveniently selected from 2 different community health centers. The experimental subjects participated in the CI movement program for 6 hours daily over a period of two weeks. The exercises for affected U/E consisted of warming up, main exercise and ADL practice. To encourage the participants' behaviors self-efficacy enhancing strategies were used, which included performance accomplishment, vicarious experience, verbal persuasion and emotional arousal. Result: After 2 weeks of treatment, the grip power, pinch power, wrist flexion/extension, elbow flexion, and shoulder flexion/extension were significantly higher in the experimental subjects than in the control subjects. However, there was no significant difference in hand functions of the two groups. Conclusion: The above results show that the constraint-induced movement using self-efficacy could be an effective nursing intervention for improving U/E function of chronic hemiplegic patients. Long term studies are needed to determine the lasting effects of constraint-induced movement.

The Effects of 'Cancer Overcome Program' Using Strategy for Promoting Self-Efficacy among Family Caregivers with Lung Cancer in Korea (자기효능증진 전략을 이용한 암극복 프로그램의 효과 II -폐암가족을 중심으로-)

  • Yang, Young Hee;Lee, Jong Kyung
    • Korean Journal of Adult Nursing
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    • v.18 no.3
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    • pp.395-404
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    • 2006
  • Purpose: This study investigated the effect of a structured group intervention on knowledge about lung cancer, self efficacy and quality of life for family caregivers of patients with lung cancer using a nonequivalent control groupquasi-experimental design. Methods: Subjects were 11 family caregivers for both the control and the experimental group. The experimental group participated in once a week for 2-hour session for 4 weeks. Four topics of educational program were lung cancer and treatment, side effects of treatments, symptoms management, and health management. Every session consisted of lecture, sharing experiences, and meditating time. Quality of life was measured using Jang(1996)'s tool. The tools for knowledge and self-efficacy were developed by the authors. Results: After the intervention, the experimental group showed higher self-efficacy in caring for the patients than did the controls. However, there were no significant differences in knowledge about lung cancer and quality of life between the two groups. Conclusion: Findings indicate that the group intervention would be effective for family caregivers of lung cancer patients.

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Post-Marketing Surveillance Study of the Safety and Efficacy of Mesoglycan Prescribed in Primary and Secondary Care of Patients with Vascular Disease (혈관질환 환자의 예방치료에 있어 메소글리칸의 안전성 및 유효성에 관한 시판 후 조사에 대한 연구)

  • Kim, Yoon-Hee;Jung, Young-Hye;Lee, Hwa-Jeong;Gwak, Hye-Sun
    • Korean Journal of Clinical Pharmacy
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    • v.15 no.2
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    • pp.94-99
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    • 2005
  • The aim of this study was to evaluate the safety and efficacy of treatment of mesoglycan. This study was conducted between September 2003 and May 2004. A total of 292 patients with vascular disorders including cerebral infarction were enrolled. The patients were administered with 50-100mg of mesoglycan by an oral route everyday for eight weeks. Subjective physicians' assessments of efficacy had ratings of 'improvement', 'invariability', 'exacerbation' and 'not being able to assess'. An improvement was observed in 241 patients out of 274; 18 patients were rules out. The efficacy rate was influenced statistically significantly by the duration of therapy (p=0.0392) and daily mean drug dose (p<0.0001). The adverse events were reported in 8 patients (9 cases) out of 292 patients: skin/appendages disorders (0.7%), liver/biliary system disorders (0.7%), cardiovascular system disorders (0.7%), neurologic disorders (0.3%). respiratory disorders (0.3%) and gastrointestinal system disorders (0.3%). There showed no serious adverse events. These results indicate that mesoglycan was well tolerated and effective for the prevention of vascular disorders.

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Effects of Telephone Consulting Program on Self-efficacy and Self-care in NIDDM Patients (전화상담 프로그램이 당뇨병환자의 자기효능과 자가간호에 미치는 효과)

  • Kim, Chun-Gill;Chung, Chung-Hee
    • Korean Journal of Adult Nursing
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    • v.14 no.2
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    • pp.306-314
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    • 2002
  • Purpose: This study was intended to examine the effects of a telephone consulting program on self-efficacy and self-care in NIDDM patients. Method: Sixty-eight NIDDM patients participated. Thirty-six were assigned to the experimental group and received the telephone consulting program from one to two times per week for 4 weeks. This program was undertaken by base on small booklet relating to diabetic disease summary, diet, drug, exercise, foot management, prevention and treatment of complications, and insulin injection methods. Result: 1. Hypothesis 1 that "the experimental group who receives the telephone consulting program will have higher self-efficacy score than the control group who does not have the telephone consulting" was supported (t=5.12, p= .000). 2. Hypothesis 2 that "the experimental group who receives the telephone consulting program will have higher self-care score than the control group who does not have the telephone consulting" was supported(t=5.29, p= .000). Conclusion: The telephone consulting program improved self-efficacy and self-care in NIDDM patients. Accordingly, this program can be adopted as an effective nursing intervention in the care of the diabetic patients.

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The Impact of a Simulation-based Education Program for Emergency Airway Management on Self-efficacy and Clinical Performance among Nurses (시뮬레이션 기반 응급기도관리 교육이 간호사의 자기효능감, 임상수행능력에 미치는 효과)

  • Lee, Mi-Ja;Jung, Dukyoo
    • Korean Journal of Adult Nursing
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    • v.26 no.1
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    • pp.1-10
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    • 2014
  • Purpose: This study was conducted to test the impact of simulation-based education program for emergency airway management on self-efficacy and clinical performance ability. Methods: A quasi-experimental non-equivalent control group pre-post test design was used. A total of 60 nurses, 30 nurses assigned to the simulation-based education group and 30 nurses to a traditional lecture group. The treatment group received a lecture, small group workshop and team simulation whereas the comparison group received lectures. Results: The participants in the simulation-based education group reported significantly higher self-efficacy of emergency airway management compared to participants in the lecture only group (t=5.985, p<.001). The simulation-based education group showed significantly higher clinical performance ability of emergency airway management compared with the lecture group (t=5.532, p<.001). Conclusion: Simulation-based education was verified to be an effective teaching method to improve the self-efficacy, clinical performance skills of nurses in the learning of emergency airway management.

Effects of a Smoking Cessation Program on Amount of Smoking and Nicotine Dependence and Self-efficacy of Smoking Cessation for Smoking Workers (금연프로그램이 흡연근로자의 흡연량과 니코틴의존도 및 자기효능감에 미치는 효과)

  • Park, Mi-Kyung;Kang, Kyung-Sook;Kim, Nam-Young
    • Journal of Korean Academy of Nursing
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    • v.37 no.7
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    • pp.1073-1079
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    • 2007
  • Purpose: The purpose of this study was to identify the effects of a smoking cessation program on the amount of smoking and nicotine dependence and the self-efficacy of smoking cessation for smoking workers. Methods: The total number of subjects was 38 smokers and was divided into two: 16 smokers were placed in the experimental group and 22 in the control group. A nonequivalent control group pretest-posttest design was used. The smoking cessation program consisted of two sessions and was implemented for two hours daily for five days. Data was analyzed by using the SPSS/WIN 11.0 program with $X^2-test$, t-test or Mann-Whitney U and ANCOVA. Results: After the treatment, those belonging to the experimental group showed a significantly decreased amount of smoking, a decreased nicotine dependency and increased self-efficacy compared to the control group. Conclusion: The smoking cessation program was effective for diminishing the amount of smoking, decreasing nicotine dependence and improving self-efficacy. Therefore, this program is recommended as a smoking cessation strategy for adult smokers.

Effects of self-care intervention using a mobile instant messenger on hemodialysis patient's knowledge, self-efficacy, self-care behavior and physiological index

  • Yu Kyung Shin;Mi Young Kim
    • Journal of Korean Biological Nursing Science
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    • v.26 no.2
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    • pp.123-135
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    • 2024
  • Purpose: The purpose of this study was to examine the effects of self-care intervention using a mobile instant messenger on hemodialysis patient's knowledge, self-efficacy, self-care behavior and physiological indices. Methods: A non-equivalent control group pretest-posttest design was used. The participants consisted of 38 patients who had a regular hemodialysis of Seoul National University Hospital. They were assigned to one of two groups; an experimental group (n = 19) that had self-care intervention for 8 weeks and a control groups (n = 19) that had routine hemodialysis treatment. The data collection was conducted from September 5, 2022 to October 29, 2022. The date were analyzed by Chi-square test, Independent t-test, and Fisher's exact test using SPSS Win 29 program. Results: There was a significant difference in self-efficacy (t = 3.42, p = .002) between experimental and control groups. There was no significant differences between the two groups in knowledge (t = 0.80, p = .428), self-care behavior (t = 0.09, p = .929), potassium (t = -0.82 p = .416), phosphorus (t = -0.03, p = .974), weight gain (t = 0.16, p = .867). Conclusion: Based on above results, it was verified that self-care intervention in this study was an effective indicator in improving the self-efficacy. There is a requirement to formulate comprehensive interventions capable of enhancing various indicators.

Effectiveness Analysis of Computer Science Textbooks focusing on Digital Therapeutics

  • Eunsun Choi;Namje Park
    • Journal of Internet Computing and Services
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    • v.25 no.3
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    • pp.9-18
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    • 2024
  • Digital therapy has emerged as a novel treatment modality, propelled by advancements in information and communication technology. In the last five years, there has been a substantial surge in research publications addressing digital therapeutics (DTx) interventions, signaling a sustained upward trajectory in this field. The dynamic nature of computer science, marked by continuous innovation and development, underscores the need for agile adaptation to rapid changes. Consequently, computer science education is compelled to offer students insights into the latest trends. This research endeavors to contribute to the evolving landscape by developing textbooks that impart knowledge about DTx, an integration of information technology. The study focuses on the application of these textbooks to elementary and middle school students in South Korea. The instructional materials have been carefully organized to enable students to learn about the principle of Attention Deficit Hyperactivity Disorder (ADHD) DTx at the elementary level and the DTx that can prevent and address the digital drama at the middle school level. Based on the application of the textbook, students who received instruction using the textbook showed statistically significant improvements in all subcategories of creative problem-solving ability, including idea modification, visualization, task focus, analogy, idea generation, and elaboration (p<.01). Additionally, there were statistically significant changes in students' self-efficacy before and after using the textbook, with negative efficacy decreasing, and positive efficacy and social efficacy increasing (p<.001).