• 국제물리치료학회지
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• 제1권2호
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• pp.91-98
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• 2010

This study is intended to examine the motor skill learning and treadmill exercise on motor performance and synaptic plasticity in the cerebellar injured rats by harmaline. Experiment groups were divided into four groups and assigned 15 rats to each group. Group I was a normal control group(induced by saline); Group II was a experimental control group(cerebellar injured by harmaline); Group III was a group of motor skill learning after cerebellar injured by harmaline; Group IV was a group of treadmill exercise after cerebellar injured by harmaline. In motor performance test, the outcome of group II was significantly lower than the group III, IV(especially group III)(p<.001). In histological finding, the experimental groups were destroy of dendrities and nucleus of cerebellar neurons. Group III, IV were decreased in degeneration of cerebellar neurons(especially group III). In immunohistochemistric response of synaptophysin in cerebellar cortex, experimental groups were decreased than group I. Group III's expression of synaptophysin was more increased than group II, IV. In electron microscopy finding, the experimental groups were degenerated of Purkinje cell. These result suggest that improved motor performance by motor skill learning after harmaline induced is associated with dynamically altered expression of synaptophysin in cerebellar cortex and that is related with synaptic plasticity.

• The Journal of Korean Physical Therapy
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• 제25권4호
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• pp.224-231
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• 2013

Purpose: The purpose of this case study was to investigate three poor fibrinolytic responders with chronic ischemic stroke to acute exercise intensity and time. Methods: Three ischemic stroke patients (male) from the stroke center located at Busan metropolitan area in Republic of Korea volunteered at this study. They performed two single session exercises that were a VO2peak test and a single bout treadmill walking (70-75%HRpeak, 30 min, 50min). Fasting blood samples for determination of tissue Plasminogen Activator (tPA) and Plasminogen Activator Inhibitor-1 (PAI-1) were obtained before, immediately after, 30min after acute exercise. SPSS 12.0 was used for analyzing of data and computing mean and standard deviation, and change rate was conducted between times. Results: In fibrinolytic activity according to the intensity and time of acute exercise, tPA change increased steadily during the recovery stage after the VO2peak in the cases, but PAI-1 activity showed different patterns among the cases. In a single bout treadmill walking (70-75%HRpeak, 30 min, 50min), tPA change increased between 30min and 50min. Conclusion: In conclusion, these results suggest that the exercise prescription for poor fibrinolytic responder with three male chronic ischemic stroke patients without motor disability recommend at 70-75%HRpeak, over 30min.

• 성인간호학회지
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• 제14권4호
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• pp.573-580
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• 2002

Purpose: The purpose of this study was to investigate the effects of a cardiac rehabilitation program for patients with myocardial infarction. Method: The subjects were 45 myocardial infarction patients(22 for experimental group and 23 for the control group). Data were collected through questionnaire survey, blood test, and the treadmill test, between October 1, 1999 and December 31, 2000. As for data analyses, paired and unpaired t-test and $\chi^2$ test were adopted using the SAS program. Result: 1. The post-test revealed that increase in compliance score of health behavior was significantly higher in the experimental group than in the control group. 2. The increase in HDL cholesterol was significantly higher in the experimental group than in the control group, in the post-test. 3. The experimental group showed significantly higher duration of exercise time and maximal METs than the control group after the program. Conclusion: The above findings indicate that a cardiac rehabilitation program was effective in increasing compliance of health behaviors, serum HDL cholesterol level, duration of exercise time, and maximal METs in patients with myocardial infarction. Accordingly, we can adopt the individualized cardiac rehabilitation programs as a nursing intervention.

• 대한물리의학회지
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• 제5권4호
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• pp.559-567
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• 2010

Purpose : The purpose of this study is to investigate the effects of motor function recovery and change of the heart function factors(ECG & Troponin I) with ischemic stroke patients by different amounts(times) exercise. Methods : Forty-six consecutive chronic hemiparetic patients with cerebral infarct were randomly assigned to two groups: Group 1 (exercise time 60 minutes/day) and Group 2 (exercise time 120 minutes/day). Types of exercise included static bicycle, isokinetic exercise, and standing or gait exercise on a treadmill. Outcome measures included the level of motor recovery (Fugl-Meyer Scale, FMS) and heart function (ECG and Troponin I), and measurements were performed three times: pre-test, 8 weeks and 12 weeks. Results : There was a significantly different change of motor function recovery and ECG between two groups during treatment period. Especially there were significantly change period of pre-test to 8 weeks on ECG and pre-test to 12 weeks on motor function recovery. But Troponin I has no significantly different change between two groups during treatment period. Also there was no significantly different change of motor function recovery and ECG and Troponin I with between two groups during treatment period. Conclusion : The exercise program improved motor function and change ECG without Troponin I in two groups. The result of this study shows that no matter how different amounts of exercise to effect of motor function recovery and heart function test in chronic patients with cerebral infarct.

• Natural Product Sciences
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• 제28권2호
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• pp.68-74
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• 2022

HemoHIM was used as a Korean traditional medicine for anti-inflammatory and antioxidant effects. However, there is no study on the effect of HemoHIM on fatigue. We examined the potential use of HemoHIM to determine whether it can induce anti-fatigue effects. Mice were administered with HemoHIM and VEH for 14 days. On the last day of treatment, mice were subjected to behavioral tests. Subsequently, their plasma and muscle were collected after the treadmill test to measure lactate, lactate dehydrogenase (LDH), ammonia, corticosterone, glycogen, and creatine kinase (CK). We found that HemoHIM moderately increased the running time (s) in the treadmill and mobility duration in the cold swimming tests. In addition, the VEH group showed a significant increase in lactate, LDH, and corticosterone levels in the plasma compared to the group that did not perform the test. However, this was moderately reduced in HemoHIM treatment. Moreover, the HemoHIM-treated group showed significant differences in LDH and glycogen levels, and showed significantly different CK levels in the muscle. HemoHIM is considered to be effective in improving fatigue, given the duration of cold swimming or running time on a treadmill. Also, HemoHIM treatment resulted in reduced concentrations of blood and muscle parameter analysis.

• 한국식품영양과학회지
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• 제40권12호
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• pp.1700-1707
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• 2011

본 연구에서는 4주간 혼합곡 식이를 공급하여 treadmill을 통한 운동시간과 glycogen 저장능력 변화를 관찰함으로써 지구력 개선에 대한 평가를 하였다. 7주령 SD rats은 정상군 (Nor, 정상식이, n=6), 대조군(Con, 20% 정상식이+80% milled rice, n=6), GI(혼합곡 식이 I, n=6), GII(혼합곡 식이 II, n=6), GIII(혼합곡 III, n=6)와 GIV(혼합곡 식이 IV, n=6)으로 임의 군배정을 하였다. 지구력 시험은 24일간의 적응훈련과 혼합곡 식이 공급을 한 후 실시하였다. 운동 지속시간과 glycogen 저장능력은 혼합곡 식이 공급에 의해서 증가하였다. 더욱이 25 min 운동 그리고/또는 탈진 시까지의 운동 후에서 혈액 내 무기질 인, CPK와 lactate의 농도는 혼합곡 투여에 의하여 감소하였으나, GOP, GTP, lactate LDH의 농도는 군간 차이는 보이지 않았다. 본 연구에서는 4주간의 혼합곡 식이가 운동 지속 시간과 glycogen 장 능력이 증가되었으며, 피로물질인 무기질 인, CPK와 lactate의 농도가 감소시킴으로써 지구력 개선에 도움을 줄 것으로 생각된다.

• The Journal of Korean Physical Therapy
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• 제29권4호
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• pp.175-180
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• 2017

Purpose: This study examined the effects of fast walking training on a treadmill on the spinal alignment and muscle thickness of normal adults. Methods: A total of 36 college students in their twenties participated in the study for eight weeks, and they were divided into the normal walking, fast walking, and speed change groups. All the groups were measured in a pre-test before training. The subjects performed exercise three times per week for six weeks. A post-test was conducted six weeks after training began, and a follow-up test was done two weeks after the training ended.Trunk and pelvic tilts were measured in Formetric 4D for the spinal alignment of the subjects. The muscle thickness was examined in the trunk with an ultrasound test. Repeated-measures ANOVA was conducted to test the main effects and interactions among the measurement variables according to time and group. Results: Significant differences were observed in the pelvic tilt according to time. There were significant differences in the external oblique, internal oblique, transverse abdominal muscle according to time. The post-test results showed significant differences in the left external oblique, internal oblique muscles between before training, six weeks into training, and two weeks after the completion of training. There were significant interactions in the left oblique muscles according to the time and group. Conclusion: These findings have some value for patient rehabilitation and clinical applications and interventions through walking training.

• PNF and Movement
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• 제14권2호
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• pp.67-74
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• 2016

Purpose: The purpose of this study was to prove the effects of coordinative locomotion training (CLT) on walking speed, walking endurance, and balance for incomplete spinal cord injury patients. Methods: Ten subjects were randomly assigned to the CLT group (n = 5) and the treadmill (TM) group (n = 5). The CLT group performed PNF pattern exercise using the motions of the sprinter and skater for 30 minutes, while the TM group performed using a treadmill for 30 minutes. Both groups performed these therapeutic interventions for five days per week, for a period of four weeks. A 10 meter walking test, Berg Balance Scale (BBS), and 6 meter walking test were used for the assessment of gait speed, balance, and gait endurance. The SPSS Ver. 18.0 statistical program was used for data processing. A Wilcoxon signed rank test was used for the comparison of pre- and post-intervention performance and a Mann-Whitney test was used for comparison between the groups. The significance level for the statistical inspection was set at 0.05. Results: Both groups showed significant improvements in the 10 meter walking test, Berg Balance Scale, and 6 meter walking test (P < 0.05). Conclusion: CLT had an effect on the improvement of walking speed, walking endurance, and the balance of incomplete spinal cord injury patients. Thus, we suggest that CLT is a therapeutic intervention for incomplete spinal cord injury patients.

• The Journal of Korean Physical Therapy
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• 제21권3호
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• pp.33-40
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• 2009

Purpose: This study examined the effects of a virtual reality-based exercise program on the functional recovery of balance and gait in chronic stroke subjects. Methods: A total of 42 chronic stroke patients were enrolled in this study. The participants were allocated randomly to 2 groups: a VR (n=22) and control group (n=20). Both groups received treadmill training for 3 sessions (10 minutes each), 30 minutes per week over a 6 week period. The VR group practiced additional virtual reality programs consisting of 3 programs for 10 minutes each. The data was analyzed using a paired t-test and independent t-test to determine the statistical significance. Results: The virtual reality-based exercise group showed significant increases in gait velocity, cadence and stride length compared to the control group (p<0.05). However, there were no significant differences in static balance. Conclusion: These results support the perceived benefits of exercise programs that incorporate virtual reality to augment the balance and ambulation of stroke patients. Therefore, virtual reality is feasible and suitable for stroke patients

• Tuberculosis and Respiratory Diseases
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• 제50권1호
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• pp.42-51
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• 2001

연구배경 : 심폐운동검사를 호흡곤란이나 운동제한의 주원인 감별을 위한 진단적 목적으로 이용시, 사용한 진단 알고리즘과 운동방법에 따른 분석결과에 차이가 있는지를 알아보고, 차이가 있다면 그 원인은 무엇인지 알아보고자 하였다. 연구방법 : 안정시 폐기능검사상 이상이 있는 만성폐질환자 66명, 운동시 호흡곤란을 호소하나 안정시 폐기능검사상 이상이 없는 환자 48명을 대상으로 자전거를 이용하여 증상 제한적 최대운동을 시행하고 Wasserman 등과 Eschenbacher 등이 제안한 진단 알고리즘을 이용 하여 분석하여 그 결과를 비교하였고, 건강한 의과대 32명을 대상으로 자전거와 답차를 이용하여 증상 제한적 최대운동을 시행한 후 Eschenbacher 등이 제안한 진단 알고리즘으로 분석후 운동방법에 따른 분석결과의 차이를 비교하였다. 연구결과 : 1) 호흡곤란을 주증상으로 호소하고 안정시 폐기능 검사상 미국흉부학회 기준에 부합하는 폐기능손상을 보이는 환자중 최근 2개월이내에 증상이 악화되지 않은 환자 66명을 대상으로 증상제한적 최대운동후 Wasserman 방식과 Eschenbacher 방식으로 해석후 비교하여 보았을 때 42명에서 일치하여 63.6%의 일치율을 보였다. 폐기능검사소견에 따라 구분하여 보면, 폐쇄성장애를 보인 경우는 43명중 30명으로 69.8%, 제한성장애를 보인 경우 8명중 2명으로 25%, 혼합성장애를 보인 경우 15명 중 10명으로 66.7%의 일치율을 보였다. 2) 임상적으로 심장질환은 의심되지 않으나 활동시 호흡곤란을 호소하고, 안정시 폐활량측정에서 정상소견을 보이는 48명을 대상으로 자전거를 이용한 운동 후 두 방식으로 분석 비교하였을 때 30명에서 일치하여 일치율은 60.4%이었다. 3) 호흡곤란 등의 호흡기계증상이 없고 안정시 폐활량검사상 정상인 건강한 의과대학 남학생 32명을 대상으로 자전거와 답차를 이용한 운동후 Eschenbacher 방식으로 해석한 결과 운동방법에 따른 일치율은 25% 이었다. 결론 : 이와 같은 결과로 진단 알고리즘 혹은 운동방법에 따라 결과가 차이가 있음을 알 수 있었고, 심폐운동검사를 호흡곤란이나 운동제한의 주원인 감별을 위한 진단적 목적으로 이용하기 위해서는 한국성인에 적용할 수 있는 운동방법에 따른 진단 알고리즘을 확립하는 것이 필요하다고 여겨진다.