• 한국ITS학회:학술대회논문집
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• v.2007 no.10
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• pp.303-307
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• 2007

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.28 no.1
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• pp.67-73
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• 2022

The food cold chain refers to a technology and distribution supply chain applied to maintain a constant temperature suitable for the product from production (harvest) to delivery to consumers. In particular, in Korea, the insulation material used in the food cold chain is mostly EPS (Expanded Polystyrene), which is used as a transport container for various food cold chains. However, according to the government's eco-friendly policy, companies charge environmental contributions to the use of EPS, but due to its low price and convenience of handling, it is still used as a container for delivering food. In this study, in order to measure the domestic delivery environment of general refrigerated foods, changes in impact, temperature, and humidity during transport of the EPS packaging system containing foods and ice pack refrigerants were measured. As a result, there were 2?3 sections in which a high impact force of 40 G or more was generated during transport. This can cause damage to the product and EPS container. The difference in temperature and humidity changes by parcel transport routes is more than 30%, so it is necessary to present accurate standards for the domestic cold chain distribution environment. As a result of microbial experiments. the transportation period had a dominant effect on the increase in total viable count and E. coli count.

• Wind and Structures
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• v.30 no.4
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• pp.405-421
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• 2020

Quayside container cranes are important delivery machineries located in the most frontiers of container terminals, where strong wind attacks happen occasionally. Since the previous researches on quayside container cranes mainly focused on the mean wind load and static response characteristics, the fluctuating wind load and dynamic response characteristics require further investigations. In the present study, the aerodynamic wind loads on quayside container cranes were obtained from wind tunnel tests. The probabilistic and spectral models of the fluctuating aerodynamic loads were established. Then the joint probabilistic distributions of dynamic wind-induced responses were derived theoretically based on a series of Gaussian and independent assumption of resonant components. Finally, the results were validated by time domain analysis using wind tunnel data. It is concluded that the assumptions are acceptable. And the presented approach can estimate peak dynamic sliding force, overturning moments and leg uplifts of quayside container cranes effectively and efficiently.

• BMB Reports
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• v.46 no.1
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• pp.17-24
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• 2013

Transcutaneous immunization refers to the topical application of antigens onto the epidermis. Transcutaneous immunization targeting the Langerhans cells of the skin has received much attention due to its safe, needle-free, and noninvasive antigen delivery. The skin has important immunological functions with unique roles for antigen-presenting cells such as epidermal Langerhans cells and dermal dendritic cells. In recent years, novel vaccine delivery strategies have continually been developed; however, transcutaneous immunization has not yet been fully exploited due to the penetration barrier represented by the stratum corneum, which inhibits the transport of antigens and adjuvants. Herein we review recent achievements in transcutaneous immunization, focusing on the various strategies for the enhancement of antigen delivery and vaccination efficacy.

• Advances in nano research
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• v.14 no.2
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• pp.165-177
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• 2023

Nanomotors are gaining popularity as novel drug delivery methods since they can move rapidly, penetrate deeply into tissues, and be regulated. The ability of manufactured nanomotors to swiftly transport therapeutic payloads to their intended location constitutes a revolutionary nanomedicine strategy. The nanomotors for the drug delivery purpose are released in the blood flow under the different physical conditions, so the stability investigation of these devices is essential before the production, especially in the sport and physical exercise conditions that the blood flow enhances. As a result, using dynamic analysis, this article investigates the stability of the nanomotor released in the blood flow when sport and physical activity circumstances increase blood flow. The considered nanodevice is made of a central motor, and nanotubes are used for the nanomotor blade, which is the drug capsule. Finally, the stability examination of nanomotor as the drug delivery equipment is discussed in detail, and the proposed results can present beneficial results in designing and producing small-scale intelligent devices.

• Journal of Korean Society of Transportation
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• v.19 no.1
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• pp.17-28
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• 2001

The purpose of this study is to analyze logistics cost of transportation systems on EC(electronic commerce) between company and consumer. Transportation system in logistics is classified by three types on EC. The first type is the direct delivery from supply factory to consumers(type I). The second type is the delivery through distribution center in each area by owner logistics company (type II). The third type is the commission of delivery to the third party logistics company(type III). The logistics of EC has various service characteristics such as dealing with small quantity, various goods, and high frequency. This study assumes that all day's order is delivered on a next day. The logistics cost function is calculated according to the number of orders, delivery distance, transport quantify. and allocated freight trucks for daily order of the subject zone. The logistics cost changes according to the daily order characteristics. Therefore it is simulated to analyze the logistics cost change that considers the type of transportation's order characteristics. As a result of analysis, if the number of order is less than 10 and the quantify of each order is less than 10kg, type III has an advantage over the others And if the number of order is more than 10 and the quantity of each order is more than 10kg, type I has an advantage in the same zone and type II has an advantage in the other zones. This study is limited on the actual application because this study doesn't consider logistics infra of supply company and transport service time. If further study that considers these factors is implemented, it can estimate more accurate logistics cost on EC and propose an efficient freight transport alternatives to the company. This study attributes to estimate the logistics cost change over the frequency of daily order, the quantify of supply goods, and the transport distance on EC.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.21 no.2
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• pp.61-65
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• 2015

Agricultural products packaged for transportation are put in the various dangerous environments owing to the damage factors like vibration, shock, compression, climate etc. under the distribution process. On fruits packaging for transportation, especially, the shock and vibration is considered as the most important damage factors. A major cause of shock damage to fruits is drops during manual handling. Especially, the damages of fruits during the parcel delivery service are very serious. The parcel delivery services of fruits are increasing and contribute to increasing of farm house earning. Also, the freight vehicle is mostly used to transport the fruits. Shock and impact generated by the freight vehicle may give serious damage to fruits. The optimum packaging design of parcel delivery service of fruits during transportation is required to reduce the fruits damages. In order to design the packaging system for parcel delivery service of fruits considering the transportation environment, the comprehension of characteristics for vibration and shock generated by manual handling and acting on transportation vehicles under various road conditions and loading methods is required. This research was performed to analyze the shock characteristics, acceleration level and power spectral density (PSD) during the parcel delivery service of fruits. The overall level of recommended PSD profile in a specific transportation of parcel delivery service for fruits was $0.63G_{rms}$.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.28 no.2
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• pp.127-132
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• 2022

The growth of e-commerce market requires more delivery packagings, which protect goods from the damage factors on the delivery. In this study, we have analyzed the distribution environment data (vibration and impact) measured in previous study and compared with global standards (ISTA, ASTM), so that we developed the testing method for Field-to-Lab simulation suitable to the domestic delivery. In order to verify the efficacy of this method, we took the Field-to-Lab tests for 3 packaged products (detergents set, glass tableware set, small furniture), which has been frequent breakages or damages on the actual delivery by e-commerce order, so that we could find out the test results were similar to those of the actual delivery occasions. In addition, we could perform redesign and improvement of the parcel delivery packagings for safe transportation by taking this Field-to-Lab test repeatedly. This test methods was finally proposed to be Korean industrial standard (KS), and is expected to be useful as a designing tool for the packaging optimization between protecting goods and reducing packaging waste.

• Journal of Platform Technology
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• v.11 no.2
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• pp.26-38
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• 2023

This paper is a study on a transport robot capable of autonomously driving to a destination using a QR code in an indoor environment. The transport robot was designed and manufactured by attaching a lidar sensor so that the robot can maintain a certain distance during movement by detecting the distance between the camera for recognizing the QR code and the left and right walls. For the location information of the delivery robot, the QR code image was enlarged with Lanczos resampling interpolation, then binarized with Otsu Algorithm, and detection and analysis were performed using the Zbar library. The QR code recognition experiment was performed while changing the size of the QR code and the traveling speed of the transport robot while the camera position of the transport robot and the height of the QR code were fixed at 192cm. When the QR code size was 9cm × 9cm The recognition rate was 99.7% and almost 100% when the traveling speed of the transport robot was less than about 0.5m/s. Based on the QR code recognition rate, an experiment was conducted on the case where the destination is only going straight and the destination is going straight and turning in the absence of obstacles for autonomous driving to the destination. When the destination was only going straight, it was possible to reach the destination quickly because there was little need for position correction. However, when the destination included a turn, the time to arrive at the destination was relatively delayed due to the need for position correction. As a result of the experiment, it was found that the delivery robot arrived at the destination relatively accurately, although a slight positional error occurred while driving, and the applicability of the QR code-based destination self-driving delivery robot was confirmed.

• Journal of Pharmaceutical Investigation
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• v.41 no.1
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• pp.9-17
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• 2011

The objective of this work is to study transdermal delivery of calcitonin using iontophoresis and to evaluate various factors which affect the transdermal transport. We have studied the effect of polarity, current density, drug concentration, penetration enhancers (isopropyl myristate [IPM] and ethanol) and laser treatment on transdermal flux and the results were compared. We also investigated the iontophoretic flux from microemulsions containing calcitonin together with oleic acid (OA) or IPM. In vitro flux study was performed at $33^{\circ}C$, using side-by-side diffusion cell and full thickness hairless mouse skin. Anodal delivery at pH 3.0 was much larger than cathodal and passive delivery, due to the positive charge of calcitonin. Cumulative amount delivered (CUM) by cathodal or passive delivery was close to zero for 10 hours. The pretreatment of skin by neat IPM markedly increased the CUM anodically. CUM increased as the current density, drug concentration or the duration of IPM treatment increased. Microemulsion containing IPM or oleic acid was prepared and the phase diagram was constructed. CUM also increased when IPM was incorporated into a microemulsion. OA microemulsion showed similar enhancing effect to IPM microemulsion. The delivery of calcitonin from 70% (v/v) ethanol aqueous solution showed a large increase in flux. Laser treatment of skin before flux experiment exhibited about 2 fold increase in total calcitonin amount transported for 12 hours, when compared to that delivered by IPM microemulsion. Based on these results, we have evaluated the possibility of delivering enough amount of calcitonin to reach the therapeutic level. The data suggest that it is highly possible to deliver clinically effective amount of calcitonin using iontophoresis patch with small area (<10 $cm^2$).