• Title/Summary/Keyword: Transient region

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Role of phospholipase D and osteopontin in reactive glial cells after transient forebrain ischemia

  • Kim, Seong-Yun
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2000.04a
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    • pp.15-16
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    • 2000
  • Transient forebrain ischemia results in delayed neuronal death in the CA1 region of the hippocampus after injury, which is, at least in part, a consequence of excessive generation of reactive oxygen species. Previous in vitro studies using cell cultures or brain slices have demonstrated that phospholipase D (PLD) in the nervous system is involved in the signaling mechanism in response to a variety of agonists. Several recent studies have shown that reactive oxygen species stimulate phospholipase D (PLD) activity in several kinds of cells. Therefore, this raises the possibility that PLD activity is enhanced in the ischemic brain. Meanwhile, osteopontin (OPN) was initially identified as a sialoglycoprotein in bone, but has since been found in various tissues. Although not much is known about its function, OPN seems to play an important role in inflammation and tissue repair. Recently, it was reported that OPN was upregulated in the activated microglia after focal brain ischemia, suggesting that OPN might play a role in wound healing after a focal stroke.

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Measurement of Heat Transfer and Pressure Distributions on a Gas Turbine Vane Endwall (가스터빈 베인 끝벽의 열전달 특성 및 정압분포 측정)

  • Lee, Yong-Jin;Shin, So-Min;Kwak, Jae-Su
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.14 no.2
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    • pp.33-38
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    • 2006
  • Heat transfer coefficients and static pressure distributions on a gas turbine vane endwall were experimentally investigated in a 5 bladed linear cascade. The Reynolds number based on an axial chord length and the cascade exit velocity was 500,000. Both heat transfer and pressure measurements on the vane endwall were made at the two different turbulence intensity levels of 6.8% and 10.8%. Detailed heat transfer coefficient distributions on the vane endwall region were measured using a hue detection based transient liquid crystals technique. Results show various regions of high and low heat transfer coefficients on the vane endwall surface due to several types of secondary flows and vortices. Heat transfer coefficient and endwall static pressure distributions showed similar trends for both turbulence intensity, however, the averaged heat transfer coefficients for higher turbulence intensity case was higher than the lower turbulence intensity case by 15%.

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Transient-Liquid-Phase Bonding of Fe-Base MA956 ODS Alloy (Fe기 MA956 산화물분산강화합금의 천이액상확산접합에 관한 연구)

  • 강지훈
    • Journal of Powder Materials
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    • v.2 no.1
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    • pp.53-62
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    • 1995
  • TLP(Transient-Liquid-Phase) bonding of Fe-base MA956 ODS alloy was performed. As insert metal a commercially available Ni-base alloy(MBF50) and an MA956 alloy with additive elements of 7wt% Si and 1wt% B were used. To confirm the idea that a concurrent use of MA956 powder with Insert metals can enhance the homogenization of constituent elements and thereby reduce the thickness of joint interface, MA956 powder was also inserted In a form of sheet. SEM observation and EDS analysis revealed that Cr-rich phase was formed in the bonded interface in initial stage of isothermal solidification during the bonding process, irrespective of kind of insert metals. Measurement of hardeness in the region of bonded interface and EDS analysis showed that a complete homogenization of composition could not be obtained especially in case of MBF50. Joints using either BSi insert metals only or BSi insert together with MA956 powder interlayer showed, however, a remarkable improvement in a compositional homogenization, even though a rapid grain growth in the bonded interface could not be hindered.

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Effects of dimple/protrusion array on heat transfer coefficients in rectangular wavy duct (주름진 덕트에서 딤플/돌출 형상이 열전달계수에 미치는 영향)

  • Kwon, Hyun-Goo;Hwang, Sang-Dong;Cho, Hyung-Hee
    • Proceedings of the KSME Conference
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    • 2008.11b
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    • pp.2352-2356
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    • 2008
  • Heat transfer and performance characteristics have been investigated for a rectangular wavy duct with dimple or protrusion arrays. The test duct was 15mm in height and 105mm wide. The print diameter of the dimple/protrusion wall was 12.99mm and the depth/height of the dimple/protrusion was 3.75mm. Local heat transfer coefficients on the dimple/protrusion wall were measured using a transient TLC technique. The Reynolds number was varied from 3,000 to 10,000. For the wavy duct tested in this study, adverse static pressure characteristics occurred at turning region of the wavy duct due to secondary flows. For the wavy duct with protrusion array, higher heat transfer enhancement level of 7.4 times than smooth straight case in maximum was obtained at low Reynolds number due to the high heat transfer enhancement by vortex flows. Also, the protrusion array increased the performance level of 3.0 at low Reynolds number of 3,000.

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Transient Ground Impedance of Small-sized Ground Electrode considering Underground Discharge in Frozen Soil (동결 토양에서 지중방전을 고려한 소규모 전극의 과도접지임피던스 특성)

  • Lee, Tae-Hyung;Cho, Sung-Chul;Eom, Ju-Hong;Lee, Bok-Hee
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2009.05a
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    • pp.324-327
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    • 2009
  • This paper presents the transient impedance in a discharge region when high voltage lightning impulse is applied to small-sized ground electrodes in frozen soil. For a realistic analysis of ionization characteristics near the ground electrode in the soil, ground rod installed outdoors and high voltage impulse voltage generator were used. From the analysis of response voltage and current flowing ground electrode to earth, it was verified that the ionization near the ground electrode contributes to reduction of ground impedance and limits the ground potential rise effectively under high impulse voltage.

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Photoinduced Electron Transfer From Aromatic Amines to Triplet States of $C_{60}$

  • Yahata, Yukio;Sasaki, Yoshiko;Fujitsuka, Mamoru;Ito, Osamu
    • Journal of Photoscience
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    • v.6 no.3
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    • pp.117-121
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    • 1999
  • Photoinduced electron transfer of C60 has been studied by the laser photolysis measuring the transient absorption bands in near-IR region. The electron transfer aromatic amines via the triplet state of C60 is confirmed by the decay of the transient absorption bands of the triplet state of C60 and the rise of the anion radical of C60 and the cation radicals of amines. The rate and efficiency of electron transfer are strongly affected by the donor ability of amines and polarity of solvents. Back electron-transfer kinetics is also strongly affected by the solvent polarity.

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An experimental study on the heat transfer augmentation by using the multiple orifice nozzle (다중 오리피스 노즐을 이용한 충돌분류의 열전달 향상에 관한 실험적 연구)

  • 김예용;정기호;김귀순;서태범
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.11 no.5
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    • pp.647-657
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    • 1999
  • An experimental study has been peformed to investigate the heat transfer characteristics of impinging jets with multiple orifice nozzles. Four different shapes of multiple orifice nozzle were tested to improve the heat transfer characteristics of impinging jet. Heat transfer coefficients were obtained by using transient and steady method based on the liquid crystal thermography, and both methods showed very similar results. The effects of multiple orifice nozzles on the heat transfer characteristics of impinging jets were discussed in detail. The results showed that multiple orifice nozzles improved the heat transfer characteristics of impinging jet. Especially, heat transfer coefficients around stagnation region of impinging jets were highly increased.

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Lateral Stability Control for Rear Wheel Drive Vehicles Using Electronic Limited Slip Differential (전자식 차동 제한장치를 이용한 후륜구동 차량의 횡방향 안정성 제어)

  • Cha, Hyunsoo;Yi, Kyongsu
    • Journal of Auto-vehicle Safety Association
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    • v.13 no.3
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    • pp.6-12
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    • 2021
  • This paper presents a lateral stability control for rear wheel drive (RWD) vehicles using electronic limited slip differentials (eLSD). The proposed eLSD controller is designed to increase the understeer characteristic by transferring torque from the outside to inside wheel. The proposed algorithm is devised to improve the lateral responses at the steady state and transient cornering. In the steady state response, the proposed algorithm can extend the region of linear cornering response and can increase the maximum limit of available lateral acceleration. In the transient response, the proposed controller can reduce the yaw rate overshoot by increasing the understeer characteristic. The proposed algorithm has been investigated via computer simulations. In the simulation results, the performance of the proposed controller is compared with uncontrolled cases. The simulation results show that the proposed algorithm can improve the vehicle lateral stability and handling performance.

Numerical Simulation of Air Flows in Human Upper Airway for Free Flap Reconstruction Following Resection Surgery in Oral Cancer Patients (구강암 절제 및 재건 수술에 따른 기도 내 공기 유동 시뮬레이션)

  • Seo, Heerim;Song, Jae Min;Yeom, Eunseop
    • Journal of the Korean Society of Visualization
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    • v.18 no.3
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    • pp.96-102
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    • 2020
  • Oral cancer surgery changes the morphologic characteristics of the human upper airway. These changes can affect the flow patterns. In this study, computational fluid dynamics (CFD) simulations with transient solver were performed to numerically investigate the air flows in the human upper airways depending oral cancer surgery. 3D reconstructed models were obtained from 2D CT images of one patient. For the boundary condition, the realistic breathing cycle of human was applied. The hydraulic diameters of cross-sections for post-surgical model are changed greatly along streamwise direction, so these variations can cause higher wall shear stress and flow disturbance compared to pre-surgical model. The recirculation flows observed in the protruding region result in the relatively large pressure drop. These results can be helpful to understand the flow variations after resection surgery of oral cancer.

Safety evaluation of agricultural reservoir embankment according to backside extension (후면 덧쌓기에 따른 농업용 저수지 제체의 안정성 평가)

  • Lee, Dal-Won;Noh, Jae-Jin
    • Korean Journal of Agricultural Science
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    • v.39 no.1
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    • pp.97-110
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    • 2012
  • This study was carried out for safety evaluation, the practical application and improvement of design method of the agricultural reservoir embankment according to backside extension. Seepage analysis, slope stability analysis and finite element analysis were performed for steady state and transient conditions. Also, the pore water pressure, seepage quantity, safety factor and stress-strain behavior according to high water level and rapid drawdown were compared and analyzed. The pore water pressure at contact region between backside extension and old embankment was kept high after rapid drawdown. Therefore, backside extension is recommended that design method is required to be improved and reinforced more than the others raising embankment. The hydraulic gradients before and after backside extension showed high value at the base of the core, but they showed stable state at the upstream slope and downstream slope. The seepage quantity per 1 day and the leakage per 100 m for the steady state and transient conditions appeared to be safe against the piping. The safety factor of slope stability showed high at the steady state, and transient conditions did not show differences depending on the rapid drawdown. The safety factor was appeared high at the upstream slope before backside extension and downstream slope after extension. The excess pore water pressure for steady state and transient conditions showed negative(-) at the upstream slope, it was small at the downstream slope. The mean effective stress (p') showed high at the base of the core and to be wild distribution after the extension. The displacement after extension showed 0.02-0.06 m in the upstream slope, the maximum shear strain after extension was smaller than that before extension.