• Title/Summary/Keyword: Transfer of Risk

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Infection Risks Faced by Public Health Laboratory Services Teams When Handling Specimens Associated With Coronavirus Disease 2019 (COVID-19)

  • Wong, Chun-Kwan;Tsang, Dominic N.C.;Chan, Rickjason C.W.;Lam, Edman T.K.;Jong, Kwok-Kwan
    • Safety and Health at Work
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    • v.11 no.3
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    • pp.372-377
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    • 2020
  • Infection risks of handling specimens associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by public health laboratory services teams were assessed to scrutinize the potential hazards arising from the work procedures. Through risk assessments of all work sequences, laboratory equipment, and workplace environments, no aerosol-generating procedures could be identified except the procedures (mixing and transfer steps) inside biological safety cabinets. Appropriate personal protective equipment (PPE) such as surgical masks, protective gowns, face shields/safety goggles, and disposable gloves, together with pertinent safety training, was provided for laboratory work. Proper disinfection and good hand hygiene practices could minimize the probability of SARS-CoV-2 infection at work. All residual risk levels of the potential hazards identified were within the acceptable level. Contamination by gloved hands was considered as a major exposure route for SARS-CoV-2 when compared with eye protection equipment. Competence in proper donning and doffing of PPE accompanied by hand washing techniques was of utmost importance for infection control.

Quantiflcation of Human Exposure and Analysis of PCBs in Contaminated Some Site (특정지역에서 토양중 PCB의 분석과 인체노출량평가)

  • 이효민;박송자;김명수;윤은경;최시내;김선태;박종세
    • Toxicological Research
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    • v.13 no.1_2
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    • pp.49-54
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    • 1997
  • PCBs are classified as B2 (Probable human carcinogen) based on the induction of hepatocellular carcinomas in rats and mice from IRIS (Integrated Risk Information System). About 20 years ago, PCBs were phased out for electrical use in Korea, but PCBs were continuously used in the other field. Lately, there has been increasing concern on possible effects of contaminated soil to the other environment and human health. The purpose of this study is to determine PCBs level in soil at some site and to assess the human exposure doses according to exposure routes for people living within sites which expected to be exposed to PCBs. Pollution level of PCBs on the site was monitored using gas liquid chromatography. To assess the transport of PCBs in soil to plant and to air, various transfer factors(diffusion coefficient, bioconcentration factor etc.) were considered in simple calculations. To calculate the residential exposure doses by routes, some equations were considered using assumption value, which define inhalation, ingestion (soil, plant) and derreal uptake pathway. Computated results will be used as risk assessment information for human health evaluation on contaminated soil.

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Quantitative Exposure Assessment of Indoor Radon Released from Groundwater (지하수로부터의 실내 라돈오염에 의한 정량적인 인체노출평가)

  • Yu, Dong-Han;Kim, Sang-Joon
    • Journal of Radiation Protection and Research
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    • v.26 no.2
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    • pp.79-86
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    • 2001
  • This study presents the quantitative exposure assessment of indoor radon released from groundwater. Most of the Indoor radon comes directly from soil beneath the basement or foundation. Recently, radon in groundwater releases to indoor air whenever the water is used and contributes to the total inhalation risk from indoor air. This study first develops a mathematical model to describe the transfer and distribution of radon released from groundwater in a house. Then, daily human exposures through inhalation or such radon are estimated with the model for an male adult based on two sets of exposure scenarios. The results obtained from the study would help increase the understanding of risk assessment issues associated with the indoor radon released from groundwater.

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Study on the Estimation of Seasonal Ambient Current for the Application of Ambient Adjusted Line Rating(AAR) in Overhead Transmission Lines Using Risk Tolerance(RT) Method (가공송전선로의 AAR 적용 시 Risk Tolerance 분석을 이용한 계절별 최대 허용전류 산정 및 적용에 관한 연구)

  • Lee, Jaegul;Bae, Youngjae;Song, Jiyoung;Shin, Jeonghoon;Kim, Yonghak;Kim, Taekyun;Yoon, Yongbeum
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.1
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    • pp.7-15
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    • 2017
  • Ambient Adjusted line Rating(AAR) method for overhead transmission lines considering Risk Tolerance(RT) was proposed in this paper. AAR is suitable for system operators to plan their operation strategy and maintenance schedule because this can be designed as a seasonal line rating. Several candidate transmission lines are chosen to apply the proposed method in the paper. As a result, it is shown that system reliability was significantly enhanced through maximizing transfer capability, solving the system constraints.

Standard Work Process to Reduce a Risk of Track Exchange Work for Railroad (철도 운행선 변경작업의 리스크 저감을 위한 표준작업 프로세스 도출)

  • Yoon, Chang Geun;Park, Su Yeul;Kim, Seok
    • Korean Journal of Construction Engineering and Management
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    • v.22 no.6
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    • pp.131-137
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    • 2021
  • Since many resources are put into the work of changing the railway operation within limited time, it is important to have a specific work plan and safety management. For this reason, the work schedule is shared in advance, and parallel work is being carried out simultaneously by rail system, such as tracks, trolly wires, and signals. However, due to the nature of the transfer work, the work is carried out at night when the railway operation is finished, and many resources are put into the limited area of the operating line, so the risk of safety accidents and failure to change the operating line is recognized as high. Nevertheless, there is still not enough research done in korea regarding the operation line change construction. Therefore, this study is conducted a survey on the track exchange work of railroad for working people, and analyzed the results of the survey. Finally, a standard work process was suggested to reduce the risk of track exchange work.

Risk Factors Associated with the Need for Operative Treatment of Intussusception in Children (소아에서 발생한 장중첩증에서 수술적 치료의 필요와 관련된 위험인자)

  • Ha, Heontak;Cho, Jayun;Park, Jinyoung
    • Advances in pediatric surgery
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    • v.20 no.1
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    • pp.17-22
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    • 2014
  • The aim of this study was to identify the risk factor related to the need for operative treatment and avoid unnecessary non-operative management for intussusception in children. We retrospectively reviewed medical records of patient treated for intussusception at our institution between January 2006 and January 2013. Clinical features such as gender, age, seasonal variation, symptoms and signs, treatment results were analyzed. Univariate and multivariate analyses including a chi-square test for categorical variables and logistic regression analysis were performed. During the study period, 356 patients were treated for intussusception. 328 (92.1%) was treated successfully by the non-operative pneumoreduction, and 28 (7.9%) required operative management. On univariate analysis, risk factors which were related to the need for operative treatment were age, vomiting, bloody stool, lethargy, and symptoms duration. A logistic regression analysis in order to assess for independent predictors of operative treatment was performed. Age (<6 vs ${\geq}12$ months) (OR 4.713, 95% CI 1.198~18.539, p=0.027) and symptoms duration longer than 48 hours (OR 4.534, 95% CI 1.846~11.137, p=0.001) were significantly associated with a requirement for operative treatment. We conclude that younger age and a longer duration of symptoms (${\geq}48$ hours) are the independent risk factor related to the need for operative treatment for intussusception. Early surgical intervention or transfer to a hospital with pediatric surgical capabilities should be considered for patients with these findings.

The Study on Takaful in Islamic Countries (이슬람국가의 타카풀보험(Takaful) 연구)

  • Kim, Jongwon
    • Journal of the Society of Disaster Information
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    • v.11 no.1
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    • pp.121-133
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    • 2015
  • A classical commercial insurance, which is used widely as the risk management methods for risk transferring and risk financing, includes the factors of interests, gambling and uncertainty, In 1985 Islamic Fiqc Academy declared that the classical commercial insurance violates the Islamic fundamental principles and beliefs, alteratively recommending a mutual insurance and takaful. A basic principle of takaful is the mutual aid in the Islamic community. On the basis of mutual aid, takaful participants (insurance policyholder) establishes the takaful fund, which is cooperation fund by participant contribution. Takaful fund is separated from shareholders' fund, and the profit and loss of takaful fund are responsible for takaful policyholder. Ownership and operation right of takaful belong to the takaful participants. In takaful, takaful company takes a role of agent or management operator. Comparing to the classical insurance, takaful has the rights of profit dividend, voting of executives, access to accounting books etc. which are additional favors for business company or individuals as takaful participants. Business companies and individuals should consider to use takaful to transfer risk and to enjoy takaful's additional advantages.

Biosafety and Biosecurity Programme: Its Implementation, Requirements and Continuous Development at the Nanyang Technological University in Singapore

  • Tun, Tin;Preiser, Peter Rainer
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.2
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    • pp.77-84
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    • 2018
  • In Singapore, biosafety and biosecurity measures are controlled by the Biological Agents and Toxins Act (BATA) and other requirements by regulatory agencies. The law prohibits and otherwise regulates the possession, use, import, transhipment, transfer, and transportation of biological agents, inactivated biological agents, and toxins that are of public health concern. The law also defines the facility requirements for high risk biological agents and toxins. The containment facility (BSL 3) is a minimum requirement to handle biological agents that falls under Schedule 1 (Risk Group 3). The Nanyang Technological University School of Biological Sciences Biosafety Level 3 Facility (NTU-SBS BSL 3) was designed specifically for research involving potential hazardous biological materials. The facility requires yearly re-certification by an approved facility certifier to meet the local requirements and international biosafety standards for a containment facility in many instances. On the other hand, most NTU researchers conduct biological projects involving biological agents with low or moderate risk groups (Risk Groups 1 and 2 or biological agents described in schedule 3 and 4 of BATA) and GMOs, which need only a BSL 2 laboratory. BSL 2 laboratories are yet to be legally certified or registered in Singapore. Institutional Biosafety Committee (IBC) identifies the requirements; defines a minimum standard in the safe control of biological risks and registers all BSL 2 laboratories in the NTU. Therefore, under the guidance of the IBC, the University Biosafety and Biosecurity Programme includes the audit and certification program as a unique and an internal exercise to bring NTU biosafety to a higher level.

A Study on a Scenario-based Information Leakage Risk Response Model Associated with the PC Event Detection Function and Security Control Procedures (PC 이벤트 탐지 기능과 보안 통제 절차를 연계시킨 시나리오 기반 금융정보유출 위험 대응 모델에 관한 연구)

  • Lee, Ig Jun;Youm, Heung Youl
    • The Journal of Society for e-Business Studies
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    • v.23 no.4
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    • pp.137-152
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    • 2018
  • It is a measure to overcome limitations that occur in the activity of detecting and blocking abnormal information leakage activity by collecting the activity log generated by the security solution to detect the leakage of existing financial information and analyzing it by pattern analysis. First, it monitors real-time execution programs in PC that are used as information leakage path (read from the outside, save to the outside, transfer to the outside, etc.) in the PC. Second, it determines whether it is a normal controlled exception control circumvention by interacting with the related security control process at the time the program is executed. Finally, we propose a risk management model that can control the risk of financial information leakage through the process procedure created on the basis of scenario.

Prediction of Prognosis in Glioblastoma Using Radiomics Features of Dynamic Contrast-Enhanced MRI

  • Elena Pak;Kyu Sung Choi;Seung Hong Choi;Chul-Kee Park;Tae Min Kim;Sung-Hye Park;Joo Ho Lee;Soon-Tae Lee;Inpyeong Hwang;Roh-Eul Yoo;Koung Mi Kang;Tae Jin Yun;Ji-Hoon Kim;Chul-Ho Sohn
    • Korean Journal of Radiology
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    • v.22 no.9
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    • pp.1514-1524
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    • 2021
  • Objective: To develop a radiomics risk score based on dynamic contrast-enhanced (DCE) MRI for prognosis prediction in patients with glioblastoma. Materials and Methods: One hundred and fifty patients (92 male [61.3%]; mean age ± standard deviation, 60.5 ± 13.5 years) with glioblastoma who underwent preoperative MRI were enrolled in the study. Six hundred and forty-two radiomic features were extracted from volume transfer constant (Ktrans), fractional volume of vascular plasma space (Vp), and fractional volume of extravascular extracellular space (Ve) maps of DCE MRI, wherein the regions of interest were based on both T1-weighted contrast-enhancing areas and non-enhancing T2 hyperintense areas. Using feature selection algorithms, salient radiomic features were selected from the 642 features. Next, a radiomics risk score was developed using a weighted combination of the selected features in the discovery set (n = 105); the risk score was validated in the validation set (n = 45) by investigating the difference in prognosis between the "radiomics risk score" groups. Finally, multivariable Cox regression analysis for progression-free survival was performed using the radiomics risk score and clinical variables as covariates. Results: 16 radiomic features obtained from non-enhancing T2 hyperintense areas were selected among the 642 features identified. The radiomics risk score was used to stratify high- and low-risk groups in both the discovery and validation sets (both p < 0.001 by the log-rank test). The radiomics risk score and presence of isocitrate dehydrogenase (IDH) mutation showed independent associations with progression-free survival in opposite directions (hazard ratio, 3.56; p = 0.004 and hazard ratio, 0.34; p = 0.022, respectively). Conclusion: We developed and validated the "radiomics risk score" from the features of DCE MRI based on non-enhancing T2 hyperintense areas for risk stratification of patients with glioblastoma. It was associated with progression-free survival independently of IDH mutation status.