• 대한한방소아과학회지
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• 제20권1호
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• pp.207-218
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• 2006

Objective : The aim of this study was to investigate treatment of childhood myopia in current Traditional Chinese Medical Journals. Material and Method : We searched for treatment of childhood myopia in all Traditional Chinese Medical Journals published from January 2001 to October 2005. Results : Thirteen articles were selected and 7 of them showed total improvement rate was higher than 90% in childhood myopia. Treatment methods were acupuncture, auricular acupuncture, moxibustion, herbal medicine, adhesive plaster. Conclusion : Oriental medical treatments for childhood myopia were presumed to be effective in most trials. But there remains a debate about diagnosis and outcome criteria. Further studies are needed.

• 척추신경추나의학회지
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• 제9권1호
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• pp.55-65
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• 2014

Objectives : The purpose of this review is to investigate the trends of traditional korean medicine treatments on frozen shoulder. Methods : We investigated the studies on traditional korean medicine treatments for frozen shoulder via searching 6 Korean web databases. As a result, 32 research papers were found to be analyzed according to their published year, the titles of journals, published institution, the types of study, the number of cases, the types of treatments, the instruments for assessment and ethical approvals. Results : 32 papers were published since 1989. The studies on traditional korean medicine treatments about frozen shoulder were mainly published in The journal of korean acupuncture & moxibustion medicine. 10 case series, 7 reviews, 6 non-randomized controlled trials, 5 randomized controlled trials and 4 case reports had been under research. In most of the research, the number of the cases were not enough. In 15 cases of the studies, various traditional korean medicine treatments were used to treat the symptoms. In 8 cases of the studies, one method was used to treat the symptoms. Range of motion(ROM) and visual analogue scale(VAS) were used as primary assessments. Among the 25 clinical studies, 5 of them were accepted by institutional review board(IRB). Conclusion : In this study, we analyzed the trends of traditional korean medicine treatments on frozen shoulder. Reviewing the domestic trends of studies on traditional korean medicine treatments for frozen shoulder and examining the strong and weak points of those treatments are essential for the future studies.

• Journal of Plant Biotechnology
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• 제5권1호
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• pp.7-11
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• 2003

The TCM (traditional Chinese medicine) transdermal plaster (also known as "cataplasma") are flexible adhesive patches used for treatment of any pain, resulted from arthritis, sprain and bruise, tendovaginitis, lumbar spine protrude, neuralgia, hyperosteogeny ache, abdominal discomfort and metastatic cancer, etc. This paper provides a review of the TCM transdermal agents for pain palliation and the preparation of these herbal patches.l patches.

• Journal of the Korean Wood Science and Technology
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• 제34권2호
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• pp.37-45
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• 2006

The viscoelastic properties of blends of melamine-formaldehyde (MF) resin and poly(vinyl acetate) (PVAc) for engineered flooring used on the Korean traditional ONDOL house floor heating system were investigated by dynamic mechanical thermal analysis (DMTA). Because MF resin is a thermosetting adhesive, the effect of MF rein was shown across all thermal behaviors. The addition of PVAc reduced the curing temperature. The DMTA thermogram of MF resin showed that the storage modulus (E') increased as the temperature was further increased as a result of the cross-linking induced by the curing reaction of the resin. The storage modulus (E') of MF resin increased both as a function of increasing temperature and with increasing heating rate. From isothermal DMTA results, peak $T_{tan{\delta}}$ values, maximum value of loss modulus (E") and the rigidities (${\Delta}E$) of MF/PVAc blends at room temperature as a function of open time, peak $T_{tan{\delta}}$ and maximum loss modulus (E") values were found to increase with blend MF content. Moreover, the rigidities of the 70:30 and 50:50 MF/PVAc blends were higher than those of the other blends, especially of 100% PVAc or MF. We concluded that blends the MF/PVAc blend ratios correlate during the adhesion process.

• 폴리머
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• 제27권6호
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• pp.596-602
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• 2003

고분자 유화제를 2-에틸헥실 아크릴레이트와 n-부틸 아크릴레이트 그리고 아크릴산 단량체를 사용하여 단량체 조성과 분자량을 변화시켜 용액중합에 의해서 합성하였다. 합성된 고분자 유화제를 이용하여 반연속식 유화중합을 통해 수성 아크릴 에멀션 점착제를 제조하였다. 그 결과, 입자크기는 약 145 nm 정도로 전형적인 유화제에 비해 상대적으로 작게 나타났고, 입자크기분포도는 단분산적 형태를 보였다. 에멀션을 이용한 동결-해빙 시험결과 기존 유화제를 사용한 경우 2회 반복 후 응집이 발견되었으나, 고분자 유화제의 경우 7회 반복 후에도 응집이 보이지 않아 저장안정성이 매우 우수함을 나타냈다. 접착시험 결과 초기점착력과 점착력은 고분자 유화제의 분자량이 증가함에 따라 또한 아크릴산 함량이 높을수록 감소하는 경향을 나타내었고, 반면 유지력은 증가하였다.

• 펄프종이기술
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• 제45권4호
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• pp.52-64
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• 2013

This study was carried out to investigate the characteristics of starch paste which was used for the conservation of paper properties. Three kinds of commercial corn starch and five kinds of fermented wheat starch were examined on the contents of amylose and amylopectin, shapes of particles, and viscosity and pH of paste. And adhesive strength on the drying, accelerated aging, and wetting treatments were measured. The contents of amylopectin of oxidized corn starch were higher those of cationic corn starch, unmodified corn starch, and fermented wheat flour. In case of fermented wheat flour, increasing of a fermentation period was resulted in increasing of amylopectin contents. The particle shapes of commercial corn starch showed with a uniform polygon, but fermented wheat flour showed with a mixture of small and large oval types. The viscosity of oxidized corn starch were very lower those of cationic corn starch and unmodified corn starch. And increasing of a fermentation period of wheat flour was resulted in increasing of viscosity. The pH of commercial corn starch were 3.6-7.5 and fermented wheat flour were 3.6-5.2. Through the examination on the nature and adhesive strength of starch paste, the oxidized corn starch 60 cps which is the name of products and wheat flour which had fermented for 5 years were considered that most suitable for conservation of paper properties.

• Journal of Microbiology and Biotechnology
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• 제32권4호
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• pp.405-418
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• 2022

Simotang oral liquid (SMT) is a traditional Chinese medicine (TCM) consisting of four natural plants and is used to alleviate gastrointestinal side effects after chemotherapy and functional dyspepsia (FD). However, the mechanism by which SMT helps cure these gastrointestinal diseases is still unknown. Here, we discovered that SMT could alleviate gastrointestinal side effects after chemotherapy by altering gut microbiota. C57BL/6J mice were treated with cisplatin (DDP) and SMT, and biological samples were collected. Pathological changes in the small intestine were observed, and the intestinal injury score was assessed. The expression levels of the inflammatory factors IL-1β and IL-6 and the adhesive factors Occludin and ZO-1 in mouse blood or small intestine tissue were also detected. Moreover, the gut microbiota was analyzed by high-throughput sequencing of 16S rRNA amplicons. SMT was found to effectively reduce gastrointestinal mucositis after DDP injection, which lowered inflammation and tightened the intestinal epithelial cells. Gut microbiota analysis showed that the abundance of the anti-inflammatory microbiota was downregulated and that the inflammatory microbiota was upregulated in DDP-treated mice. SMT upregulated anti-inflammatory and anticancer microbiota abundance, while the inflammatory microbiota was downregulated. An antibiotic cocktail (ABX) was also used to delete mice gut microbiota to test the importance of gut microbiota, and we found that SMT could not alleviate gastrointestinal mucositis after DDP injection, showing that gut microbiota might be an important mediator of SMT treatment. Our study provides evidence that SMT might moderate gastrointestinal mucositis after chemotherapy by altering gut microbiota.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4807-4814
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• 2012

Purpose: The chemoresistance of human hepatocellular carcinoma (HCC) to cytotoxic drugs, especially intrinsic or acquired multidrug resistance (MDR), still remains a major challenge in the management of HCC. In the present study, possible mechanisms involved in MDR of HCC were identified using a 5-fluorouracil (5-FU)-resistant human HCC cell line. Methods: BEL-7402/5-FU cells were established through continuous culturing parental BEL-7402 cells, imitating the pattern of chemotherapy clinically. Growth curves and chemosensitivity to cytotoxic drugs were determined by MTT assay. Doubling times, colony formation and adherence rates were calculated after cell counting. Morphological alteration, karyotype morphology, and untrastructure were assessed under optical and electron microscopes. The distribution in the cell cycle and drug efflux pump activity were measured by flow cytometry. Furthermore, expression of potential genes involved in MDR of BEL-7402/5-FU cells were detected by immunocytochemistry. Results: Compared to its parental cells, BEL-7402/5-FU cells had a prolonged doubling time, a lower mitotic index, colony efficiency and adhesive ability, and a decreased drug efflux pump activity. The resistant cells tended to grow in clusters and apparent changes of ultrastructures occurred. BEL-7402/5-FU cells presented with an increased proportion in S and G2/M phases with a concomitant decrease in G0/G1 phase. The MDR phenotype of BEL-7402/5-FU might be partly attributed to increased drug efflux pump activity via multidrug resistance protein 1 (MRP1), overexpression of thymidylate synthase (TS), resistance to apoptosis by augmentation of the Bcl-xl/Bax ratio, and intracellular adhesion medicated by E-cadherin (E-cad). P-glycoprotein (P-gp) might play a limited role in the MDR of BEL-7402/5-FU. Conclusion: Increased activity or expression of MRP1, Bcl-xl, TS, and E-cad appear to be involved in the MDR mechanism of BEL-7402/5-FU.

• 한국의류산업학회지
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• 제10권4호
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• pp.479-488
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• 2008

The purpose of this study was to re-interpret the traditional patterns in modern point of view and connect them to the apparel textile design to use them widely in our real life. For this, a documentary research on the traditional patterns and arabesque patterns was made first, and then, through the manual and photoshop workings, two apparel textile designs were suggested. As a result, the followings were acquired: First, the arabesque pattern, which is a traditional pattern of Korea, has a continuous life power and a natural formative characteristics. In its pattern, there is an abundant possibility of change. So, it has a wide usability regardless of time and space. As the symbolic image of the arabesque pattern is connected with the instinctive beauty sense of human beings, it has shown the more adhesive affinity that any other materials. Second, two kinds of textile design were suggested. The motif of work 1, "Fragrance of Woman," was the richness and the harmony, and so a lotus arabesque pattern was selected to present its concept, "Classic Elegance." The expression technique was to use a manual work and cloths to make it a voluminous one. The motif of work 2, "Green Field" was to show the clean beauty with a lotus arabesque pattern. Its concept was the "Natural Elegance," and the expression technique was to repeat the motif by using the Adobe Photoshop to complete the work.

• 대한치과교정학회지
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• 제31권1호
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• pp.137-147
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• 2001

Acidic primer는 하나의 용액으로 conditioning과 priming을 동시에 시행하는 새로운 접착 시스템으로 치질의 손상이 적고 처리 과정이 간단한 특징을 지닌다. 본 실험은 acidic primer를 이용하여 치면처리를 시행한 후 기존의 접착제로 브라켓을 접착할 때 적절한 결합강도를 지니는지 평가하기 위하여 고안되었다. 50개의 사람 소구치를 5개군으로 나누어 4개군은 acidic primer로 법랑질을 처리한 후 Clearfil Liner bond $2^{\circledR}$(1군), Transbond $XT^{\circledR}$(2군), Panavla $21^{\circledR}$(3군), Fuji Ortho $LC^{\circledR}$(4군)로 브라켓을 접착하였고 1개군은 TransHond $XT^{\circledR}$를 통상적인 산부식 방법을 이용하여 접착(5군)한 후 전단 결합 강도를 측정하고 접착파절의 양상을 평가하여 다음과 같은 결론을 얻었다. 1 Acidic primer로 처리한 4개의 군 가운데 광중합형 글래스 아이오노머를 사용한 군(4군)의 전단결합강도($9.72{\pm}3.16MPa$)와 Panavia $21^{\circledR}$을 사용한 군(3군)의 전단 결합 강도($8.69{\pm}2.72MPa$)는 37$\%$ 인산으로 처리한 후 광중합형 레진 (Transbond $XT^{\circledR}$)을 사용한 군(5군)의 전단결합강도($10.48{\pm}2.60MPa$)와 유의성있는 차이를 보이지 않았다 (P>0.05). 2. Acidic primer로 처리한 4개의 군 가운데 광중합형 글래스 아이오노머를 사용한 군(4군)과 Panavia $21^{\circledR}$을 사용한 군(3군)의 전단 결합 강도는 Clearfil Liner bond $2^{\circledR}$를 사용한 군(1군)의 전단 결합 강도($1.09{\pm}0.53MPa$)와 광중합형 레진(Transbond $XT^{\circledR}$)을 사용한 군(2군)의 전단 결합 강도($2.70{\pm}1.46MPa$)에 비해 유의하게 큰 강도를 보였다 (p<0.05). 3. 접착제 잔류지수 측정 결과 4군($2.1{\pm}1.1$)과 5군($2.9{\pm}0.3$)의 경우 1군($0.2{\pm}0.4$), 2군($0.3{\pm}0.9$), 3군($0.2{\pm}0.4$)에 비해 접착제 잔류지수가 유의하게 높았다 (p<0.05). 4. 4군과 5군의 접착제 잔류 지수간에는 유의한 차이가 없었다 (p>0.05). 따라서 acidic primer로 치면을 처리하는 방법은 시용되는 접착제에 따라 기존의 산부식 접 착법과 유사한 결합강도를 얻을 수 있어 교정용 브라켓 접착시 산부식 단계를 생략할 수 있는 가능성을 보여준다.