• Korean Journal of Clinical Laboratory Science
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• v.55 no.2
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• pp.93-104
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• 2023

This study aimed to identify new markers that cause lung adenocarcinoma by analyzing mutation hotspots for the top five genes with high mutation frequency in lung adenocarcinoma in Koreans by next generation sequencing (NGS) analysis. The association between TP53 mutation types and patterns with smoking, a major cause of lung cancer, was examined. The clinicopathological characteristics of lung adenocarcinoma patients with TP53 P72R SNPs were analyzed. In Korean lung adenocarcinoma cases, regardless of the smoking status, the TP53 P72R SNP was the most frequently occurring mutational hotspot, in which the nucleotide base was transversed from C to G, and the amino acid was substituted from proline to arginine at codon 72 of TP53. An analysis of the clinicopathological characteristics of lung adenocarcinoma cases with TP53 P72R SNP revealed no significant correlation with the patient's age, gender, smoking status, and tumor differentiation, but a significant correlation with low stage (P-value =0.026). This study confirmed an increase in TP53 rather than EGFR, which was reported as the most frequent mutations in lung adenocarcinoma in Koreans through NGS. Among them, TP53 P72R SNP is the most frequent regardless of smoking status.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.4
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• pp.799-808
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• 2007

BACnet is an international standard communication protocol especially designed for building automation and control systems. BACnet uses the Master-Slave/Token-Passing (MS/TP) protocol as one of its field-level networks. A BACnet MS/TP field controller prototype and MS/TP network monitoring system are developed in this study. This report introduces the design and implementation methodology of a BACnet MS/TP field controller hardware, firmware and protocol stack. This report also presents the implementation methodology of BACnet MS/TP network monitoring system using VTS (Visual Test Shell). The methodologies introduced in this report will facilitate the develop and implementation of the BACnet-based control systems in building automation area.

• Food Science of Animal Resources
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• v.39 no.1
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• pp.35-44
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• 2019

The composition of turmeric powder (TP) can affect the quality properties and storage characteristics of pyeonyuk; however, the appropriate addition level of TP in pyeonyuk has not been established. To address this, an experiment was designed with one control and three TP treatments: control (TP 0%), T1: (TP 0.1%), T2: (TP 0.3%), and T3: (TP 0.5%). All the TP treatments markedly increased protein and ash contents compared to the control. The water holding capacity was equally retained with the control and T3 treatments, but was significantly lower with the T1 and T2 treatments in pyeonyuk (p<0.05). Lightness and redness values were both reduced with the addition of TP, whereas the yellowness value increased. Values for 2-thiobarbituric acid reactive substances and the total microbial count for pyeonyuk with added TP showed an improvement over time. As a result, the addition of TP did not have a significant negative influence on the quality characteristics of the pyeonyuk with addition of 0.5% TP being particularly effective for water retention capacity and inhibition of lipid oxidation.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.60 no.11
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• pp.2083-2087
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• 2011

The SiC-$ZrB_2$ composites were produced by subjecting a 40:60 vol.% mixture of zirconium diboride($ZrB_2$) powder and ${\beta}$-silicon carbide (SiC) matrix to spark plasma sintering(SPS). Sintering was carried out for 60sec at $1400^{\circ}C$ (designation as TP145 and TP146), $1500^{\circ}C$(designation as TP155 and TP156) and uniaxial pressure 50MPa, 60MP under argon atmosphere. The physical, electrical, and mechanical properties of the SiC-$ZrB_2$ composites were examined. The relative density of TP145, TP146, TP155 and TP156 were 94.75%, 94.13%, 97.88% and 95.80%, respectively. Reactions between ${\beeta}$-SiC and $ZrB_2$ were not observed via x-ray diffraction (hereafter, XRD) analysis. The flexural strength, 306.23MPa of TP156 was higher than that, 279.42MPa of TP146 at room temperature, but lower than that, 392.30MPa of TP155. The properties of a SiC-$ZrB_2$ composites through SPS under argon atmosphere were positive temperature coefficient resistance (hereafter, PTCR) in the range from $25^{\circ}C$ to $500^{\circ}C$. The electrical resistivities of TP145, TP146, TP155 and TP156 were $6.75{\times}10^{-4}$, $7.22{\times}10^{-4}$, $6.17{\times}10^{-4}$ and $6.71{\times}10^{-4}{\Omega}{\cdot}cm$ at $25^{\circ}C$, respectively. The densification of a SiC-$ZrB_2$ composite through hot pressing depend on the sintering temperature and pressure. However, it is convinced that the densification of a SiC-$ZrB_2$ composite do not depend on sintering pressure under SPS.

• The Transactions of the Korea Information Processing Society
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• v.4 no.11
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• pp.2651-2661
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• 1997

We can get very enhanced performance in case of adding the TP monitor to the on_line transaction processing system rather than just using the DBMS. Futhermore, It is getting boomed to establish a OLTP system with the TP monitor. We designed and implemented a distributed processing system with the TP monitor focused quick response time and expansionality and basic the ACID of transaction. In this paper, We explain the implementation about downsizing and upon distributed system and verified of performance.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.15 no.3
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• pp.59-65
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• 2015

To build a flexible network than traditional transport network, the carrier ethernet technology is emerging in network industry recently and MPLS-TP technologies are being applied as a major standard technology for the carrier ethernet. However, network management technologies required to handle equipment installed in MPLS-TP network are not clear. This paper propose an efficient method to build a management network automatically without any additional configuration when network equipments are installed in MPLS-TP network. The proposed scheme reduce cost required for both equipment installation and network maintenance by minimizing configuration procedures of connecting management system with network. We evaluated the effectiveness of the proposed scheme by applying the scheme to a real MPLS-TP equipment.

• Journal of Institute of Control, Robotics and Systems
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• v.12 no.11
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• pp.1144-1155
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• 2006

Digital communication networks have become a core technology in advanced building automation systems. BACnet(Building Automation and Control networks) is a standard data communication protocol designed specifically for building automation and control systems. BACnet adopts Master-Slave/Token-Passing(MS/TP) protocol as one of its field level networks. In this study, we introduce a method of implementing a bandwidth allocation scheme in the MS/TP protocol. The bandwidth allocation scheme improves the capability of real-time communication of the original MS/TP protocol. The bandwidth allocation scheme introduced in this paper can be easily implemented in the existing MS/TP protocol with a slight modification. In this study, we actually developed the hardware and firmware of the modified MS/TP communication module in which the bandwidth allocation scheme is implemented. Using the modified MS/TP communication module, we developed an experimental model in order to examine the validity of the bandwidth allocation scheme in the MS/TP protocol. Experimental results show that the modified MS/TP protocol satisfies the requirements of real time communication for periodic and urgent messages of BACnet communication services.

• Korean Journal of Ecology and Environment
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• v.40 no.2
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• pp.223-233
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• 2007

For this study, we analyzed spatial and temporal patterns of trophic state and water quality over the period of $2002{\sim}2005$, using the water chemistry dataset obtained from the Korea Rural community & Agriculture corporation. Most reservoirs, based on TN, showed eutrophic (about 88% of the total). About 20% of agricultural reservoirs, based on TP, showed eutrophic after the criteria of OECD (1982), while 71% and 3% were Hesotrophic and oligotrophic, respectively. Seasonal variations were evident due to the intense monsoon rain during July${\sim}$August; conductivity, COD, SS, nutrients, and chlorophyll-${\alpha}$ (CBL) increased in the postmonsoon compared to the premonsoon. TP values had positive functional relations with conductivity, COD, and CHL values. COD and SS peaked during the intense monsoon. Mean values of TP and CHL values were two times greater in the intense monsoon than the weak monsoon. The increased TP was probably due to inorganic suspended solids from point and non-point sources during the monsoon. Ratios of TN : TP had strong in- verse relations ($R^2$=0.843, p<0.001, n=34) with TP, but not with TN (p>0.05, n=34). Log10-transformed CHL increased with TP in most P-limited reservoirs $(Log_{10}TP=0.5{\times}Log_{10}CHL+0.086)$. Similarity analysis, based TN, TP, and CHL showed that three groups were separated at 90% similarity level; One group was reservoirs with high salinity nearby the seawater, and the other two groups were reservoirs with a low salinity of the inland, and intermediate salinity, respectively.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.3
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• pp.692-700
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• 2016

This study was aimed at investigating the residual patterns of thiamphenicol (TP) in the cultured olive flounder (Paralichthys olivaceus) and black rockfish (Sebastes schlegeli) following oral administration. TP concentration were detected by high performance liquid chromatography with UV detector. The recovery rates of TP in serums ranged 77.05~97.23% (olive flounder) and 89.96~97.11% (black rockfish) for the concentration of 0.1, 1.0, $10{\mu}g/mL$, respectively. After single administration of TP (100 mg/kg body weight) by oral route in olive flounder ($700{\pm}50g$, $23{\pm}1.5^{\circ}C$) and black rockfish ($500{\pm}30g$, $23{\pm}1.5^{\circ}C$), the concentration in the serum was determined at 1, 5, 10, 15, 24, 30, 50, 168, 264 and 432 h post-dose. Two-compartment model was applied to analyze in the pharmacokinetics of TP administered to the fishes. In the serum of olive flounder, TP was detected on 10 and 15 hours after treatment were $10.08{\mu}g/mL$ and $10.06{\mu}g/mL$ as maximum level, respectively. In the serum of black rockfish, TP was detected on 15 hours after treatment were $8.88{\mu}g/mL$ as maximum level. Concentrations of TP to the fishes were not measurable at 432 hours (18 days) after treatment in all samples. Similar residual patterns of TP were revealed between the fishes. These results are helpful for estimating withdrawal time of TP which has been already in use for farmed fish treatment.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2006.11a
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• pp.62-63
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• 2006

This experiment was conducted to investigate the dietary effect of turmeric powder (TP) on laying performances, egg qualities and its transfer to eggs. A total of two hundred, 60-wk-old, Lohmann Brown layers were divided into 4 groups, placed in to 5 replicates per group (10 layers each) and fed each one of four diets containing 0 % TP(control), 0.1 % TP, 0.25 % TP, or 0.5 % TP for 7 wks, respectively. Egg production and egg mass in groups fed diets containing TP were higher than that of control(p<0.05). No differences in feed intakes, egg and eggshell qualities were observed among the treatments, but egg yolk color was increased significantly as TP was in increased in the diet(p<0.05). In groups fed diets containing TP, Haugh unit after 14 day of storage was significantly higher than that of control(p<0.05). The curcumin content of egg yolk in groups fed diet containing 0.50% TP was significantly higher than those of other groups (p<0.05). The content of egg yolk cholesterol was not influenced by dietary TP.