• Imaging Science in Dentistry
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• 제53권1호
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• pp.53-60
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• 2023

Purpose: This study evaluated maxillary sinus volume changes in military jet aircraft pilot candidates before and after the training program, in comparison with a control group, considering the effects of pressurization, altitude, and total flight hours, through multislice computed tomography. Materials and Methods: Fifteen fighter pilots were evaluated before initiating the training program and after the final approval. The control group consisted of 41 young adults who had not flown during their military career. The volumes of each maxillary sinus were measured individually before and at the end of the training program. Results: When comparing the initial and final volumes in the pilots, a statistically significant increase was observed both in the left and right maxillary sinuses. When evaluating the average total volume of the maxillary sinuses(i.e., the average volume of the right and left maxillary sinuses together), a significant increase in the volume of the maxillary sinuses was observed in the pilot group when compared to the control group. Conclusion: The maxillary sinus volumes in aircraft pilot candidates increased after the 8-month training program. This may be explained by changes in the gravitational force, the expansion of gas, and positive pressure from oxygen masks. This unprecedented investigation among pilots might lead to other investigations considering paranasal sinus alterations in this singular population.

• 한국터널지하공간학회 논문집
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• 제11권3호
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• pp.229-242
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• 2009

본 논문에서는 터널굴착으로 발생한 지표면에서의 최대 침하 및 수평변위와 총 침하부피량을 추정하기 위하여 서로 상이한 지층에서 다양한 깊이 및 직경, 서로 다른 시공조건(지반손실량)을 가진 터널에 대해 수치해석을 수행하였다. 수치해석 결과로부터 얻어진 지표면에서의 최대 침하량은 터널 굴착부 천단에서의 최대 침하량과 지층별, 터널직경 및 깊이, 시공조건(지반손실량)별로 비교되었으며, 또한 지표면에서의 최대 침하량은 지표면에서의 최대 수평변위량과도 비교하였다. 뿐만 아니라, 터널굴착부에서 발생한 지반손실량($V_L$)과 지표면에서 형성된 총 침하부피량($V_s$)을 지층 및 터널깊이와 직경을 달리하여 상호 비교하였다. 수치해석을 통해 얻어진 결과는 그 적용성과 타당성을 검증하기 위하여 기존 현장계측자료와의 비교가 수행되었으며, 이를 통해 본 연구의 수치해석 결과가 향후 터널굴착으로 발생된 주변 지반의 거동을 파악하고 분석하는 실무자료로서 활용될 수 있다는 것을 파악하였다.

• 공업화학
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• 제29권3호
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• pp.325-329
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• 2018

본 연구에서는 항산화성분함량이 높다고 알려진 안젤리카를 이용하여 폴리페놀을 추출하고 반응표면분석법을 이용하여 추출과정을 최적화하였다. 반응표면분석법의 반응치로는 추출수율과 폴리페놀함량을 설정하였고, 추출공정의 계량인자로는 추출시간, 주정/초순수 부피비, 추출온도를 이용하였다. 추출수율과 폴리페놀함량 모두 계량인자의 주효과도와 교호효과도를 모두 고려하였을 때 가장 큰 영향을 미치는 인자는 추출시간이었다. 또한 반응표면분석 결과 안젤리카의 최적추출조건은 추출시간이 2.8 h, 주정/초순수 부피비 64.0 vol%, 추출온도 $56.6^{\circ}C$로 나타났다. 이 조건의 추출수율은 24.6%, 폴리페놀함량은 8.76 mg GAE/g으로 산출되었다. 추출수율과 폴리페놀함량에 대한 회귀방정식의 결정계수 $R^2$은 각각 81.4%와 75.4%이었으며, 종합 만족도는 D = 0.80, 유의성은 5% 이내의 수준에서 인정되었다.

• 한국물환경학회지
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• 제30권6호
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• pp.585-595
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• 2014

The temporal trends of the prioritized toxic water pollutants generated and discharged from the industrial facilities in the Geum-River basin, Korea were analyzed with the results of the nationwide Water Pollution Source Survey conducted in 2001 - 2012. The statistical results indicated rapid increase in the volume of raw toxic wastewaters whereas the amount of each toxic pollutant kept fluctuating for 12 years. Serious discrepancies in the survey data of the same type of industries demonstrated a low reliability of the survey result, which stemmed from several error factors. A unit-load for each type of industrial facility was devised to estimate the amount of prioritized toxic water pollutant based on the total volume of industrial wastewater generated from the same type of industrial facilities. The supplementary measures with an effective permit issuance policy and adding survey parameters of terminal wastewater treatment plants to use them as references to the Water Pollution Source Survey were suggested as means to minimize the errors associated with the false reports from the industries.

• 동의생리병리학회지
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• 제19권4호
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• pp.993-999
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• 2005

This research was peformed to investigate protective effect of Sophora Subprostrata fractions against focal ischemic brain damage after middle cerebral artery(MCA) occlusion using intraluminal suture. Rats were divided into six groups: MCA-occluded group(Control): each administered groups with Sophora Subprostrata total phase(Total), Sophora Subprostrata Aqueous phase (Aqueous), Sophora Subprostrata BuOH phase(BuOH), and Sophora Subprostrata Alkaloid phase(Alkaloid) after MCA-occlusion; sham-operated group(Sham). The right MCA was occluded by A poly-L-lysine coated 4-0 nylon suture thread through the internal carotid artery permanently. Sophora Subprostrata and fractions were administered orally(Smg/ml) for 7 days after MCA-occlusion. The Drain tissue was stained with $2\%$ triphenyl tetrazolium chloride on ischemic brain tissue(2mm section). The results showed that 1) Sophora Subprostrata total phase reduced infarct size and total infarct volume compared to the control group at 24 hours after MCA-occlusion, 2) Sophora Subprostrata Aqueous phase reduced infarct size and total infarct volume compared to the control group at 24 hours after MCA-occlusion, 3) Sophora Subprostrata Alkaloid phase reduced infarct size compared to the control group at 24 hours after MCA-occlusion, but 4) at 7 days after MCA-occlusion, Sophora Subprostrata did not show effective recovery compared with control group. Sophora Subprostrata has protective effects against brain damage at the early stage of focal cerebral ischemia. Sophora Subprostrata total and Aqueous phase produced more pronounced protective effect against focal ischemic brain damage.

• 한국식품과학회지
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• 제29권2호
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• pp.343-347
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• 1997

Lactobacillus brevis, L. fermentum과 L. plantarum의 혼합젖산균을 사용하여 배양조건이 밀가루 용액의 발효에 미치는 영향을 살펴보았다. 온도변화에 따른 pH와 총적정산도의 변화를 살펴본 결과 pH의 감소와 총적정산도의 증가가 가장 크게 나타난 $35^{\circ}C$를 밀가루 발효의 최적온도로 선정하였다. 5L발효조에서 질소가스를 1.0 vvm으로 첨가한 혐기적 조건보다 공기를 첨가한 호기적 조건에서 총적정산도의 증가와 pH의 감소가 더 크게 나타났다. 최적 산소공급 조건을 찾기 위하여 통기량을 1.0 vvm으로 고정하고 교반속도를 달리하여 밀가루 용액의 발효한 결과 총적정산도가 가장 크게 나타난 교반속도 250 rpm에 해당되는 산소 전달속도상수 $60\;hr^{-1}$에서 최적이었다. 선정된 최적 배양조건에서 밀가루 발효액의 생산성을 높이기 위하여 반복비율을 변화시키면서 pH-stat를 이용한 반복 유가식 배양을 수행하였다. 반복비율이 증가할수록 반복 간격시간은 증가하였으나 밀가루 발효의 최대 작동시간은 감소하였다. 최적 반복비율을 결정하기 위하여 단위시간 당 배양부피 당 생산된 밀가루 발효액의 부피와 최대가동시간 동안 배양부피 당 생산된 총 밀가루 발효액의 부피를 살펴본 결과 20%의 반복비율에서 최대값을 나타내었다. 혼합젖산균을 이용한 밀가루용액의 유가식 배양에서 최적조건은 배양온도 $35^{\circ}C$, 통기량 1.0 vvm, 산소전달속도 $60\;hr^{-1}$, 반복비율 20%로 나타났다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제32권4호
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• pp.137-143
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• 2021

Objectives: Despite the growing concern regarding the adverse effects related to problematic smartphone use (PSU), little is known about underlying morphologic changes in the brain. The brainstem is a deep brain structure that consists of several important nuclei associated with emotions, sensations, and motor functions. In this study, we sought to examine the difference in the volume of brainstem substructures among adolescents with and without PSU. Methods: A total of 87 Korean adolescents participated in this study. The PSU group (n=20, age=16.2±1.1, female:male=12:8) was designated if participants reported a total Smartphone Addiction Proneness Scale (SAPS) score of ≥42, whereas the remaining participants were assigned to the control group (n=67, age=15.3±1.7, female:male=19:48). High-resolution T1 magnetic resonance imaging was performed, and the volume of each of the four brainstem substructures [midbrain, pons, medulla, and superior cerebellar peduncle (SCP)] was measured. Analysis of covariance was conducted to reveal group differences after adjusting for effects of age, gender, whole brainstem volume, depressive symptoms, and impulsivity. Results: The PSU group showed a significantly smaller volume of the SCP than the control group (F=8.273, p=0.005). The volume of the SCP and the SAPS score were negatively correlated (Pearson's r=-0.218, p=0.047). Conclusion: The present study is the first to reveal an altered volume of the brainstem substructure among adolescents with PSU. This finding suggests that the altered white matter structure in the brainstem could be one of the neurobiological mechanisms underlying behavioral changes in PSU.

• Asian-Australasian Journal of Animal Sciences
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• 제29권1호
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• pp.73-79
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• 2016

The objective was to evaluate the effect of fodder tree species (FTS) with condensed tannin contents: Cordia elaeagnoides, Platymiscium lasiocarpum, Vitex mollis, and Haematoxylon brasiletto, on in vitro methane ($CH_4$) production at 24 h post incubation. The analysis was performed using the in vitro gas production technique, with three levels of inclusion/species: 600, 800, and 1,000 mg and with 4 replicates/species/level of inclusion. The substrate was incubated at $39^{\circ}C$, and the gas and $CH_4$ production were recorded at 4, 8, 12, and 24 h post incubation. The data collected was analyzed through Pearson correlation, polinomial regression and fixed effects models. There were negative correlations between FTS-total gas volume (r = -0.40; p<0.001); FTS-volume of $CH_4$ produced (r = -0.40; p<0.001) and between the inclusion level-volume of $CH_4$ produced (r = -0.20; p<0.001). As well as a positive correlation between hours post incubation-total gas volume (r = 0.42; p<0.001) and between hours post incubation-volume of $CH_4$ produced (r = 0.48; p<0.001). The FTS: C. elaeagnoides, V. mollis, and H. brasiletto have potential, in the three inclusion levels analyzed, to reduce $CH_4$ emission on in vitro trials (>32.7%), taking into account the total $CH_4$ production at 24 h of the forage used as reference (Avena sativa). It's suggested that C. elaeagnoides-according to its crude protein, neutral detergent fiber, and condensed tannins content- is the best alternative within the FTS analyzed, for feeding ruminants and for the control of $CH_4$ emissions during the dry season.

• International Journal of Oral Biology
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• 제41권3호
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• pp.133-139
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• 2016

The ultrastructural parameters related to synaptic release of endings which are presynaptic to tooth pulp afferent terminals (p-endings) were analyzed to understand the underlying mechanism for presynaptic modulation of tooth pulp afferents. Tooth pulp afferents were labelled by applying wheat-germ agglutinin conjugated horseradish peroxidase to the rat right lower incisor, whereafter electron microscopic morphometric analysis with serial section and reconstruction of p-endings in the trigeminal oral nucleus was performed. The results obtained from 15 p-endings presynaptic to 11 labeled tooth pulp afferent terminals were as follows. P-endings contained pleomorphic vesicles and made symmetrical synaptic contacts with labeled terminals. The p-endings showed small synaptic release-related ultrastructural parameters: volume, $0.82{\pm}0.45{\mu}m^3$ ($mean{\pm}SD$); surface area, $4.50{\pm}1.76{\mu}m^2$; mitochondrial volume, $0.15{\pm}0.07{\mu}m^3$; total apposed surface area, $0.69{\pm}0.24{\mu}m^2$; active zone area, $0.10{\pm}0.04{\mu}m^2$; total vesicle number, $1045{\pm}668.86$; and vesicle density, $1677{\pm}684/{\mu}m^2$. The volume of the p-endings showed strong positive correlation with the following parameters: surface area (r=0.97, P<0.01), mitochondrial volume (r=0.56, P<0.05), and total vesicle number (r=0.73, P<0.05). However, the volume of p-endings did not positively correlate or was very weakly correlated with the apposed surface area (r=-0.12, P=0.675) and active zone area (r=0.46, P=0.084). These results show that some synaptic release-related ultrastructural parameters of p-endings on the tooth pulp afferent terminals follow the "size principle" of Pierce and Mendell (1993) in the trigeminal nucleus oralis, but other parameters do not. Our findings may demonstrate a characteristic feature of synaptic release associated with p-endings.

• 한국산림과학회지
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• 제89권3호
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• pp.414-421
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• 2000

본(本) 연구(硏究)는 경기도 포천군 소흘면에 소재한 23년생(年生)의 방크스소나무 인공림(人工林) 임분(林分)을 대상으로 연년(連年) 재적생장량(材積生長量)과 재적생장율(材積生長率)을 구명(究明)하고 현실(現實) 임분축적(林分蓄積)을 파악(把握)함과 동시에 연년(連年) 재적생장량(材積生長量)을 구명(究明)하므로서 년간 벌채량(伐採量)의 조절(調節)을 합리적(合理的)으로 책정할 수 있으므로 적정(適正) 임목축적(林木蓄積)의 달성(達成) 및 유지(維持)를 위한 기초자료(基礎資料)를 제시(提示)코저 하였다. 본(本) 연구(硏究)에서는 재적생장량(材積生長量)을 합리적(合理的)으로 산출(算出)하기 위하여 표준지별(標準地別)로 흉고직경(胸高直徑), 수고(樹高), 수피후(樹皮厚)와 최근(最近) 10년동안의 core의 길이를 측정하였다. 이들의 측정치(測定値)을 이용하여 직경계별(直徑階別)로 연년(連年) 직경생장량(直徑生長量) 및 95%신뢰폭(信賴幅)의 재적생장량(材積生長量)을 산출(算出)하고 아울러 수고곡선식(樹高曲線式)을 유도(誘導)한 후 본(本) 식(式)을 이용(利用)하여 수고(樹高)값을 산출(算出)하였다. 재적표(材積表)를 이용한 재적산출(材積算出)은 본(本) 수고(樹高)값을 적용(適用)하였다. 본(本) 수종(樹種)의 재적생장관계(材積生長關係)를 구명(究明)한 결과(結果) 연년(連年) 재적생장율(材積生長率)은 7.7%이고 이의 추정오차율(推定誤差率)은 6.1%이었다. 재적(材積)은 ha당 $79.58m^3$이었고 연년(連年) 재적생장량(材積生長量)은 $6.13m^3$이었으며 이를 95%의 신뢰폭(信賴幅)으로 본다면 $5.77{\sim}6.51m^3$이었다.