• Title/Summary/Keyword: Total Risk

Search Result 5,703, Processing Time 0.04 seconds

Application of Modified Mupit for the Recurrent Vulva Cancer in Brachytherapy

  • Kim, Jong-Sik;Jung, Chun-Young;Oh, Dong-Gyoon;Song, Ki-Won;Park, Young-Hwan
    • 대한방사선치료학회:학술대회논문집
    • /
    • 2005.06a
    • /
    • pp.23-26
    • /
    • 2005
  • Introduction: To evaluate whether modified MUPIT applicator can effectively eradicate recurrent tumor in uterine cervix cancer and reduce rectal complication after complete radiation treatment. Methods and Materials: Modified MUPIT applicator basically consists of an acrylic cylinder with flexible brain applicator , an acrylic template with a predrilled array of holes that serve as guides for interstitial needles and interstitial needles. CT scan was performed to determine tumor volume and the position of interstitial needles. Modified MUPIT applicator was applied to patient in operation room and the accuracy for position of interstitial needles in tumor volume was confirmed by CTscan. Brachytherapy was delivered using modified MUPIT applicator and RALS (192-Ir HDR) after calculated computer planning by orthogonal film. The daily dose was 600cGy and the total dose was delivered 3000cGy in tumor volume by BID. Rectal dose was measured by TLD at 5 points so that evaluated the risk of rectal complication. Result: The application of modified MUPIT applicator improved dramatically dose distributions in tumor volume and follow-up of 3 month for this patient was clinically partial response without normal tissue complication, Rectal dose was measured 34.1cGy, 57.1cGy, 103.8cGy, 162.7cGy, 165.7cGy at each points, especially the rectal dose including previous EBRT and ICR was 34.1cGy, 57.1cGy Conclusion: Patients with locally recurrent tumor in uterine cervix cancer treated with modified MIUPIT applicator can expect reasonable rates of local control. The advantages of the system are the fixed geometry Provided by the template and cylinders, and improved dose distributions in irregular tumor volume without rectal complication

  • PDF

Associations among the health status, behavior, and periodontitis in Korean adults with metabolic syndrome (한국 성인 대사증후군의 건강상태 및 건강행동과 치주염의 관련성)

  • Han, Su-Jin
    • Journal of Korean society of Dental Hygiene
    • /
    • v.20 no.3
    • /
    • pp.313-324
    • /
    • 2020
  • Objectives: The aim of this study was to confirm the association among the health status, health behaviors, and periodontitis according to total, age and sex in cases of adult metabolic syndrome(MetS). Methods: This cross-sectional study used collected data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES) conducted from 2016 to 2018 with 3,394 adults with MetS aged 19-79 years. The complex samples logistic regression analysis confirmed the relevant factors for periodontitis. Results:Periodontitis was diagnosed in 43.6% of all MetS cases. Diabetes (Odds Ratio [OR]=1.554), abdominal obesity (OR=1.336), current smoking (OR=2.465), past smoking (OR=1.379), and not-using oral care products (OR=1.414) were associated with periodontitis in MetS. In the age of 19-39 years with MetS group, diabetes (OR=5.379), elevated blood pressure (OR=3.975), current smoking (OR=7.430), and not using oral care products (OR=3.356) were associated with periodontitis. In the 40-79 age group, diabetes (OR=1.398), abdominal obesity (OR=1.360), current smoking (OR=2.022), and not using oral care products (OR=1.416) were associated with periodontitis. In the male MetS group, current smoking (OR=3.119), past smoking (OR=1.625), and brushing teeth more than three times (OR=0.743) were associated with periodontitis. In the female MetS group, diabetes (OR=1.733), impaired fasting glucose (OR=1.434), abdominal obesity (OR=1.479), and not using oral care products (OR=1.992) were associated with periodontitis. Conclusions: Improvement in blood sugar control, obesity, smoking cessation, and oral health education, including how to use oral care products in all individuals with MetS may result in improved oral health. In addition, improvement in elevated blood pressure in the MetS group aged under 40 years, and brushing teeth more than three times a day in the male MetS group can reduce the risk of periodontitis. Therefore, public and oral health professionals should emphasize on the relationship between age and sex during the metabolic syndrome management program and share relevant information with patients.

Analysis of relationship between job stress and turnover intention of physical therapists (물리치료사의 직무스트레스와 이직의도의 관련성 분석)

  • Wang, Joong-San;Kim, Yang-Rae
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.16 no.9
    • /
    • pp.6112-6119
    • /
    • 2015
  • This study attempted to examine the job stress and turnover intentions of physical therapists and to investigate the relationship between these two factors. A total of 309 physical therapists currently working in Gyeonggi-do and Incheon in South Korea were selected as research subjects. The data were collected by a survey using self-administered questionnaires structured from June 10 to June 25, 2015. According to the study results, job stress was highest in job autonomy and lowest in relationship conflict, while the turnover intention score was $2.80{\pm}0.70$. The physical therapists showed higher job stress and turnover intention level with increasing age and working experience, showing a significant positive correlation(p<.05). The turnover intention showed a significant positive correlation with all of the job stress factors. Decreased work motivation showed a significant positive correlation with all of the job stress factors except for job instability(p<.05). In addition, among the factors for the job stress, Job autonomy, Structure and organization, Inappropriate compensation, and Workplace culture turned out to be those affecting their turnover intention. This study confirmed that an increase of job stress among physical therapists can be a risk factor of higher turnover intention, implying a necessity to try to reduce their job stress and turnover intention.

A Meta-analysis of Influencing Mediator Athletics on the Metabolic Syndrome Risk Factors Utilized Big Data Analysis (빅 데이터 분석을 활용한 대사증후군 위험요인에 관한 메타분석)

  • Yu, Ok-kyeong;Cha, Youn-soo;Jin, Chan-yong;Kim, Do-goan;Nam, Soo-tai
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.19 no.11
    • /
    • pp.2590-2596
    • /
    • 2015
  • A meta-analysis is a statistical integration method that delivers an opportunity to overview the entire result of integrating and analyzing many quantitative research results. This study will find meaningful mediator variables for criterion variables that affects between pre and post in the metabolic syndrome studies, on the basis of the results of a meta analysis. We reviewed a total of 36 studies related the metabolic syndrome published in Korean journals between 2000 and 2015, where a cause and effect relationship is established between variables that are specified in the conceptual model of this study. In this meta-analysis, the path between pre and post in the waist circumference showed the biggest effect size (r = .420). The second biggest effect size (r = -.402) was found the path between pre and post in the high density lipoprotein cholesterol. By the way, one the smallest effect size (r = .234) was obtained the path between pre and post in the diastolic blood pressure. Thus, we present the theoretical and practical implications of these results.

Clinical and Statistical Analysis with Age in Cases of Pediatric Burn Patients (소아 화상 환자 2,795례에 대한 연령별 임상 통계학적 분석)

  • Cho, Ki-Hyun;Jang, Young-Chul;Lee, Jong-Wook;Koh, Jang-Hyu;Seo, Dong-Kook;Choi, Jai-Ku
    • Archives of Plastic Surgery
    • /
    • v.38 no.4
    • /
    • pp.445-450
    • /
    • 2011
  • Purpose: The objective of this study is to analyze the epidemiological characteristics of pediatric burn patients and to determine the targets for a pediatric burn prevention program. Methods: A retrospective review of all medical records of acute pediatric burn patients (age < 15 years old) admitted to our hospital between January 2005 and December 2009 was performed. Results: 1472 males and 1323 females were investigated, with a male to female ratio of 1.11 : 1. The greatest number of burn patients were those with an age of 1~2 years (1,463, 52.3%). Scalding burn was the most common cause of injury, which accounted for 2183 (78.1%) patients, followed by contact burns (10.5%), flame burn (4.9%), steam burn (3.6%). Especially steam burn was the second cause of injury in the age under 1 year, while flame burn was the second cause of injury in the age over 7 years. During recent 5 years, incidence of flame burn, steam burn, electrical burn gradually decreased. Variation of seasonal incidence is minimal and most of the patients (2,716 cases, 97.2%) had burns less than 20% TBSA (Total body surface area). The median hospital stay was 18.79 days, and the rate of operation was 28.6% with a high rate in electrical burn (76.2%), flame burn (50.0%), steam burn (46.1%). 6 patients died in this series, which yielded a mortality rate of 0.2%. Conclusion: Prevention efforts should reflect recent study results. Focused prevention program and campaign to make people aware of risk factors and their avoidance is required to reduce the number of burn accidents in children.

Estimation of the Optimum Installation Depth of Soil Moisture Sensor in an Automatic Subsurface Drip Irrigation System for Greenhouse Cucumber (시설오이 지중관비시 자동관수센서의 적정 매설깊이)

  • Lim, Tae-Jun;Kim, Ki-In;Park, Jin-Myeon;Noh, Jae-Seung
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.46 no.2
    • /
    • pp.99-104
    • /
    • 2013
  • Vegetables production in greenhouse are typically intensely managed with high inputs of fertilizers and irrigation water, which increases the risk of ground-water nitrate contamination. In 2010 and 2011, a study was conducted to determine the appropriate depth of soil moisture sensor for automatic irrigation control to use water and nitrogen efficiently under subsurface drip irrigation (SDI) systems. The irrigation line for SDI placed 30 cm below soil surface and tensiometer was used as soil moisture sensor. Three tensiometer treatments placed at 10 (SDI-T10), 20 (SDI-T20) and 30 cm (SDI-T30) depths below soil surface under SDI. These are also compared to SUR-T20 treatment where tensiometer placed at 20 cm below soil surface under surface drip irrigation (SUR) systems. The growth of cucumber was not statistically different between SUR and SDI without SDI-T30 treatment. Fruit yields (Mg/ha) were 57.0 and 56.9 (SDI-T10), 56.0 and 60.5 (SDI-T20), 40.9 and 41.2 (SDI-T30) and 56.6 and 54.3 (SUR-T20) for 2010 and 2011, respectively. Slightly higher total yield was observed in tensiometer placed 20 cm below the soil surface, although no significant differences were found between SDI-T10 and SDI-T20 under SDI treatments. In addition, nitrogen application rates and daily irrigation rates were lowest in SDI-T20 compared with other SDIs and SUR treatments. Nitrogen and daily irrigation application under SDI-T20 was lower than that under SUR-T20 by 6.0%. These findings suggested tensiometer 20 cm depth under SDI systems was best for cucumber production in greenhouse.

The Effect of Total Dose of Radiation on Normal Colon of Hybrid Mice (치료방사선 조사가 잡종 백색마우스의 대장에 미치는 병리조직학적 영향)

  • Jho, Gil-Ho;Kim, Myung-Se
    • Radiation Oncology Journal
    • /
    • v.4 no.2
    • /
    • pp.99-105
    • /
    • 1986
  • Optimal balance between control probability and risk of complication is emphasized even in present time, Although certain incidence of intestinal injury is accepted as an inevitable consequence after abdominopelvic irradiation, these complications still remain as problems. 60 mice were irradiated with 250 kVp orthovoltage x-ray machine and $200rad{\times}5/wk$ regimen. Histpathologic findings of colorectum and the relationship with occult blood test were analyzed and possible tolerable dose which would be safe from permanent complication was also estimated. Followings are the results: Mild mucosal and submucosal edema were observed in 1,000 rad irradiated group. Congestion of small vessels was prominent in 2,000 rad irradiated group and infiltration of inflammatory cells was observed in 3,000 rad irradiated group. Denuded mucosa was observed in 3,000 rad irradiated group. Occult blood test is not a proper indicator for rectal denuding or rectal ulcer, but our results suggest the possibility of using this as a relative scale of intestinal damage. Mitotic figures of crypt cells were observed even in 5,000 rad irradiated group, these suggest that the repair capacity of crypt cells are still functioning.

  • PDF

Pretreatment Effect on the Analysis of Insoluble Hexavalent Chromium (전처리방법에 따른 불용성 6가 크롬 분석에 관한 연구)

  • Lee, Eun Jung;Roh, Jae Hoon;Won, Jong Uk;Chun, Mi Ryonng;Cho, Myung Hwa;Kim, Chi Nyon
    • Journal of Korean Society of Occupational and Environmental Hygiene
    • /
    • v.6 no.2
    • /
    • pp.292-300
    • /
    • 1996
  • Hexavalent chromium($Cr^{+6}$) compounds are considered to be particularly hazardous, primarily because of the associated risk of allergic reaction and cancer. The analytic method of hexavalent chromium such as the s-diphenylcarba-zide(DPC) method and all ether previously used methods are often made uncertain due to significant interferences from organic components. This report can provide a technique for the more rapid and simple determination of total hexavalent chromium. than other currently using methods. The s-diphenylcarbazide method proposed by the U.S. National Institute for Occupational Safety and Health has low recovery rate(15.67 - 48.20%) due to interference, iron chloride and nickel chloride. A microwave oven technique has high recovery rate(about 70%) of insoluble hexavalent chromium. For the difference of ionic charges of $Cr^{+3}$-ethylenediamine tetraacetic acid(EDTA) chelate and $CrO_4{^{-2}}$, we could detect them simultaneously by ion exchanged high performance liquid chromatography. The confirmation of $Cr^{+3}$ and $Cr^{+6}$ were checked by fraction collector and flameless atomic absorption spectrometer. We observed that the small amount of hexavalent chromium is converted to trivalent chromium due to enhancement of chromium reduction by $Fe^{+3}$ or $Ni^{+2}$. As a result of this study, on the analysis of insoluble hexavalent chromium with microwave oven was used for, it may be better and more precise analysis after pretreatment by 2% NaOH-3% $Na_2CO_3$ and then analysis UV-spectrophotometer. It should be done for various studies on insoluble hexavalent chromium on the basis work environmental monitoring so called welding, painting etc.

  • PDF

Clinical Characteristics of Bacteremia in Children with Cancer (단일기관에서 소아암 환자에서 화학요법 중 발생한 균혈증의 임상 양상)

  • Chang, Mi Sun;Sung, Ki Woong;Kim, Yae Jean
    • Pediatric Infection and Vaccine
    • /
    • v.18 no.2
    • /
    • pp.201-206
    • /
    • 2011
  • Purpose : Bacteremia is one of the most common causes of morbidity and mortality in children with cancer. The aim of this study was to evaluate the clinical features of bacteremia in pediatric cancer patients. Methods : We retrospectively analyzed bacteremia episodes occurred in pediatric cancer patients at Samsung Medical Center from January 2008 to December 2010. We excluded bacteremia episodes after hematopoietic stem cell transplantation. Results : A total of 141 blood cultures were positive in 121 patients. Thirteen cultures due to contamination were excluded. For analysis, 128 bacteremia episodes in 108 children were included. Gram-positive organisms accounted for 46.9% (60/ 128) and gram-negative organisms for 53.1% (68/128). The source of bacteremia was identified in 21.1% of episodes. Bacteremia due to catheter related infection was observed in 9.4% of episodes (12/128 episodes) and gram-positive organisms were isolated in 75% of episodes (9/12). There were 10 cases (7.8%) of bacteremia associated with septic shock and gramnegative organisms were isolated in 80% of episodes (8/10). Relapses were documented within 30 days in 2 patients who cleared bacteremia which was confirmed after negative blood cultures. Mortality associated with bacteremia was not observed. Conclusion : Continuous monitoring is needed to maintain the tailored strategies to manage pediatric cancer patients with neutropenic fever who are at high risk of developing bacteremia in each institution.

Epidemiology and Clinical Severity of the Hospitalized Children with Viral Croup (바이러스성 크루프로 입원하는 소아 환자의 역학적 특성과 임상적 중증도 평가)

  • Jeon, In Soo;Cho, Won Je;Lee, Jeongmin;Kim, Hwang Min
    • Pediatric Infection and Vaccine
    • /
    • v.25 no.1
    • /
    • pp.8-16
    • /
    • 2018
  • Purpose: In this study, the clinical and epidemiological characteristics of patients admitted for viral croup were analyzed to evaluate disease severity based on the organism that caused the infection. Methods: We retrospectively reviewed the medical records of 302 patients who were admitted to the Department of Pediatrics at the Wonju Severance Hospital between May 2013 and December 2016 for viral croup. Patients who showed positive results on multiplex polymerase chain reaction were subsequently diagnosed with respiratory virus infection. The Westley scoring system was used to evaluate the severity of viral croup. Results: Of the 302 patients, 149 were admitted due to severe viral croup, including 88 boys and 61 girls, with a boy-to-girl ratio of 1.44:1. About 110 cases of parainfluenza virus infection have been reported, which accounted for almost half of the total cases. The other identified viruses included influenza virus, human rhinovirus, and respiratory syncytial virus. Analysis of the association between severe viral croup and causative pathogen revealed that only parainfluenza type 2 virus showed a significantly high risk. Parainfluenza type 2 virus did not show an age-based difference in frequency but showed relatively a higher frequency of infections during the summer and fall. Conclusions: In this study, parainfluenza virus type 2 was the only virus associated with severe viral croup. To facilitate proper preventive management, treatment, and prognosis evaluation of viral croup, prospective and multicenter studies should assess the additional variables and the severity of the virus. Additionally, further studies should be conducted to assess age-dependent influences, as well as the regional and seasonal incidence of viral infection.