• Title/Summary/Keyword: Total Risk

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Clinical trial to evaluate the efficacy and safety of Tongxinluo in high risk group of cardiovascular diseases (심혈관질환 고위험군에 대한 통심락(通心絡)의 유효성 및 안전성 평가를 위한 임상시험)

  • Park, Seong Uk;Jung, Woo Sang;Moon, Sang Kwan;Go, Chang Nam;Cho, Ki Ho;Kim, Young Suk;Bae, Hyung Sup
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.6 no.1
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    • pp.25-32
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    • 2005
  • Background and purpose: Arterial stiffness is an important, independent determinant of cardiovascular risk. Pulse wave velocity (PWV) has been used as a valuable index of arterial stiffness and as a surrogate marker for atherosclerosis. The Framingham risk score was developed using categorized risk factors to predict the 10 year absolute risk of developing coronary heart disease (CHD). This algorithm is established using recommended guidelines for blood pressure, total cholesterol, and high density lipoprotein cholesterol in addition to age, smoking history and history of diabetes. Tongxinluo(TXL) has been shown to have anti hyperlipidemic activity and anti atherogenic effects. To determine its efficacy and safety, we examined whether TXL improves PWV, ABI, Framingham score, blood pressure, and lipid profile in high risk group of cardiovascular diseases. Subjects and methods: 49 subjects with the high risk of cardiovascular diseases were recruited. Subjects were administered TXL with the dose of 1110mg three times a day for 8 weeks. baPWV, ABI, Framingham risk score, Blood pressure and serum lipid profile were assessed at baseline and after 4 and 8weeks. Results: Total cholesterol, LDL cholesterol, triglyceride, total lipid and phospolipid significantly decreased after 4 weeks of medication. Total cholesterol, total lipid and phospolipid significantly decreased after 8 weeks of medication. There were no significant changes in Framingham risk scores, ABI, PWV and blood pressure. On safety assessment, there were no adverse effects, hepatic or renal toxicity. Conclusion: We suggest that TXL is a safe and useful herbal medicine for hyperlipidemia and as for anti-atherognic effects, further research would be necessary.

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The Design of Total Safety System for Improving Productivity (생산성 향상을 위한 총체적 안전 시스템의 설계)

  • 김병석
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.23 no.59
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    • pp.79-84
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    • 2000
  • Korean industries have been tend to depending upon historical information to control risk. The other hand, foreign industries have been identify risk factors using system safety techniques to predict future risk. One agency or person could not solve the problems of total safety system for improving productivity. In order to solve those problems, the production-safety group is necessary, and safety control system must be adapted by fitting to the production flow. This paper is present the methodology of driving occupational safety programs to increase productivity.

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A Multi-Group Analysis of Risk Management Practices of Public and Private Commercial Banks

  • REHMAN, Khurram;KHAN, Hadi Hassan;SARWAR, Bilal;MUHAMMAD, Noor;AHMED, Wahab;REHMAN, Zia Ur
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.11
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    • pp.893-904
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    • 2020
  • The study examines the relationship between credit risk and operational risk (understanding of risk management, risk identification, risk assessment and control, and risk monitoring) on risk management practices followed by private and public sector commercial banks. The cross-sectional data method was used to check the impact of risk management practices. Data was collected from the bank employees and a total of 284 respondents were finally selected for further analysis. Measurement Invariance of Composite Models analysis is used to test the quality of the measurement model for sub-samples, and multi-group analysis is used for path analysis in sub-sample through PLS-SEM. The findings of the study as the total sample show that both types of banks are managing adequate and significant risk management practices. On the other hand, sub-groups' results show private sector banks are more momentous than public sector banks. Risk identification is significantly different at the sub-group level, which shows public sector banks are more concentrating on this type of risk. Understanding of risk management has no significant effect on both types of banks and risk assessment & control for public sector banks, and there is a difference in the risk management practices among private and public sector commercial banks.

Short-term effects of fertilizer application on soil respiration in red pine stands

  • Kim, Choonsig;Jeong, Jaeyeob;Bolan, Nanthi S.;Naidu, Ravi
    • Journal of Ecology and Environment
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    • v.35 no.4
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    • pp.307-311
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    • 2012
  • This study was conducted to evaluate the dynamics of soil respiration (total soil and heterotrophic respiration) following fertilizer application in red pine forests. Fertilizer (N:P:K = 113:150:37 kg/ha), which reflects current practices in Korean forest, was applied in April 2011, and total soil and heterotrophic respiration rates were monitored from April 2011 to March 2012. Monthly variation of total soil and heterotrophic respiration rates were similar between the fertilizer and control treatments, as soil temperature was the dominant factor controlling the both rates. Total soil respiration rates during the study period were not significantly different between the fertilizer (0.504 g $CO_2\;m^{-2}\;h^{-1}$) and control (0.501 g $CO_2\;m^{-2}\;h^{-1}$) treatments. However, the proportion of heterotrophic respiration was higher in the fertilizer (78% of total soil respiration rates) than in the control (62% of total soil respiration rates) treatments. These results suggest that current fertilizer practices in Korea forest soil do not substantially affect total soil respiration rates.

Reduction of eco-toxicity risk of heavy metals in the rotary drum composting of water hyacinth: Waste lime application and mechanisms

  • Singh, Jiwan;Kalamdhad, Ajay S.;Lee, Byeong-Kyu
    • Environmental Engineering Research
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    • v.20 no.3
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    • pp.212-222
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    • 2015
  • Experiments were conducted on the immobilization of eight heavy metals (HMs) (Zn, Cu, Mn, Fe, Ni, Pb, Cd, and Cr) during 20-day rotary drum composting of water hyacinth. The Tessier sequential extraction procedure was used to investigate the fractionation of HMs. The eco-toxicity risk of HMs was assessed by risk assessment code (RAC). In the results, the bioavailability factor (BAF) for different HMs presented in the following order: Mn > Zn = Fe > Cu > Cr > Cd = Pb > Ni. The total concentration of Pb was higher than that of Zn, Cu, Mn, Cd and Cr; however, its BAF was the lowest among these HMs. These results confirmed that the eco-toxicity of HMs depends on bioavailable fractions rather than on the total concentration. The greatest reduction in bioavailability and eco-toxicity risk of HMs occurred in lime 1% and 2% as compared to control and lime 3%. The eco-toxicity risk of Fe, Ni, Pb, Cd and Cr was reduced from low risk to zero risk by rotary drum composting. These studies demonstrated the high efficiency of the rotary drum for degrading compost materials and for reducing the bioavailability and eco-toxicity risk of HMs during the composting process.

How Does Internal Control Affect Bank Credit Risk in Vietnam? A Bayesian Analysis

  • PHAM, Hai Nam
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.1
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    • pp.873-880
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    • 2021
  • The purpose of this study is to investigate the impact of internal control on credit risk of joint stock commercial banks in Vietnam from 2007 to 2018. Furthermore, we specify bank-specific characteristics and macroeconomic conditions, and analyze how these factors affect credit risk of banks: the number of board members, the number of board members with banking or finance background as ratio of total board members, loans to total assets ratio, loans to deposit ratio, the number of days between the year-end and the publication of the financial statements, and the use of top four auditing firms proxy for five elements of internal control. By using the dataset of 30 Vietnamese joint stock commercial banks and Bayesian linear regression via Random-walk Metropolis Hastings algorithm, the results of this study show that five elements of internal control have a impact on bank credit risk, namely, control environment, risk assessment, control activities, information and communication, and monitoring activities. For factors of banks' characteristics, bank size and financial leverage have a negative impact on banks' credit risk, and bank age has a positive effect. For macroeconomic factors, inflation has a positive impact and economic growth has a negative impact on banks' credit risk.

Fate and Risk Comparison of Foodborne Pathogens in Raw Chicken, Pork, and Beef Meat at Various Temperatures

  • Yoon Ki Sun
    • Journal of the FoodService Safety
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    • v.3 no.2
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    • pp.49-58
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    • 2022
  • The objectives of this study were to investigate the behavior characteristics of pathogenic E. coli, Salmonella Typhimurium, Campylobacter jejuni, and Listeria monocytogenes in various kinds of meat (beef, chicken, and pork) and to compare their risk using FDA-iRISK. The growth of S. Typhimurium in chicken and pathogenic E. coli in pork and beef was well supported and posed a high risk. A similar trend was observed in the risk comparison results using the iRISK. When comparing total disability adjusted life years (DALY) per year based on the kinds of meat, chicken was the highest (88.2), followed by pork (58.5) and beef for "yukhoe" (18.8). When comparing scenarios grouped by bacteria, The highest total DALYs per year was observed with pathogenic E. coli (121), followed by S. Typhimurium (44.8) and L. monocytogenes (1.67E-3). These results indicate that the risk of combining meat and foodborne pathogens varies under the same distribution environment. Thus, strict management and supervision are required to store and deliver raw meat to prevent cross-contamination among the raw meats at the processing plant and retail market.

Derivation of Soil Fluorine Standards Based on a Human Health Risk Assessment Method (위해성 평가 기법에 따른 토양 불소 기준안 연구)

  • Seung-Woo Jeong
    • Journal of Soil and Groundwater Environment
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    • v.29 no.3
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    • pp.14-22
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    • 2024
  • This study established risk-based fluoride soil contamination standards according to the Korean Soil Contaminant Risk Assessment Guidelines (SRAG). Ten exposure scenarios were evaluated, broadly categorized into Scenario 1, which used the default parameters from the current SRAG, and Scenario 2, which used the latest exposure factors and bio-concentration factors. Fluoride soil standards corresponding to a total hazard index (HI) of 1.0 were determined for each scenario. For children in agricultural areas, the derived risk-based soil fluoride standard was 70 mg/kg for Scenario 1 and 27 mg/kg for Scenario 2. In industrial areas, the risk-based fluoride soil standard was 2200 mg/kg in Scenario 1 and 2300 mg/kg in Scenario 2. This study clearly demonstrated that the crop ingestion exposure pathway exerted predominent influence on the estimated human health risk standards. Additionally, using the Added Risk Approach and considering soil background concentrations, the total fluoride soil standards for residential areas ranged from 232 mg/kg to 444 mg/kg, while the standards for industrial areas ranged from 2405 mg/kg to 2674 mg/kg.

Factors Affecting the Financial Structure of Hospitals in Korea (병원의 재무구조에 영향을 미치는 요인)

  • 최만규;문옥륜;황인경
    • Health Policy and Management
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    • v.12 no.2
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    • pp.43-75
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    • 2002
  • This study focuses on the factors that make the financial structure of hospitals in Korea different, and on recommended courses of action that could be very helpful to hospitals in maintaining a sound financial structure. Data used in this study were collected from 132 hospitals with complete general data of present conditions as well as financial statements. They were chosen from the 174 hospitals that passed the standardization audit undertaken by the Korean Hospital Association from 1996 to 2000 for the purpose of accrediting training hospitals. The dependent variable in this study is financial structure. It consists of liabilities as against total assets (total liabilities to total assets, short-term liabilities to total assets, long-term liabilities to total assets, short-term borrowings to total assets, long-term borrowings to total assets). The independent variables are ownership type, hospital type, location, whether or not a representative is a director of the hospital, the possibility of changing a hospital director, bed size, period of establishment, asset structure, profitability, growth, tax shields, business risk, competition. The factors that appear to have the strongest impact on the liabilities to total assets of all the hospitals sampled are ownership type, hospital type, profitability, tax shields, and business risk. It was found that not-for-profit private hospitals and for-profit private hospitals have more liabilities than public hospitals, and tertiary medical institutions have less liabilities than the secondary general hospitals. Moreover, hospitals earning more at the expense of high business risk have a distinct tendency to lower liabilities. Concerning the current ratio, it was found that factors such as ownership type, hospital type, period of establishment, asset structure, and business risk are the more significant variables. The current ratio of public hospitals is higher than that of both not-for-profit private hospitals and for-profit private hospitals, and the current ratio of tertiary medical institutions is higher than that of general hospitals. As business risk is higher in hospitals compared to other businesses, the current ratio becomes higher; this is because it is assumed that for fear of bankruptcy, hospitals lessen liabilities to total assets. On the other hand, as hospitals become older, the fixed assets to total assets become lower. It is remarkable that in hospitals, the factors affecting liabilities to total assets have an opposite regression coefficient sign against factors affecting current ratio. It brings out the same results borne out by the old financial theories and researches, in which a lot of the liabilities of hospitals are considered as the cause of worsening liquidity. Therefore, it is very important for hospitals to maintain a sound financial structure in order to survive using the rational acquisition and maintenance of capital.

An Analysis of Risk Factors in Stomal Recurrence after Total Layngectomy (후두전적출술후 기관공재발의 위험요소 분석)

  • Park, Ji-Hoon;Kim, Hyung-Jin;Oh, Byung-Hoon;Choi, Geon;Jung, Kwang-Yoon;Choi, Jong-Ouck
    • Korean Journal of Bronchoesophagology
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    • v.6 no.1
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    • pp.80-86
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    • 2000
  • Background : Stomal recurrence that occasionally follows total laryngectomy is associated with very poor prognosis regardless of treatment modality, so it is very important to identify high risk patients to prevent stomal recurrence. Objectives : We attempted to select an optimal management method to prevent stomal recurrence by analyzing risk factors in each patient who was found to have stomal recurrence following total laryngectomy. Materials and Methods : Risk factors in each of eleven patients who had stomal recurrence out of 159 patients who underwent total laryngectomy in the last ten years were analyzed retrospectively. Data were gathered on risk factors such as the presence of subglottic extension, extralaryngeal extension, thyroid gland invasion, lymph node metastasis, timing of tracheotomy, tumor stage, postoperative radiotherapy, and inclusion of the stoma in the radiotherapy field. Results : There were eight cases of subglottic extension, six cases of extralaryngeal invasion, one case of pharyngocutaneous fistula that occurred as a postoperative complication, and one case who was taken completion laryngectomy following conservation surgery. With the exception of one case who was taken tracheotomy prior to total laryngectomy, all tracheotomies were performed intra-operatively after endotracheal intubation. There was no evidence of paratracheal lymph node or prelaryngeal lymph node metastasis on preoperative neck CT scan. There were six cases of T4 tumors, four cases of T3 tumors, and one case of T2 tumor. Salvage surgery was performed following radiotherapy in three cases, and aside from one case who was not taken post-operative radiotherapy, postoperative radiotherapy including the stoma was performed in the remaining seven cases within one month after surgery. Conclusion : Total laryngectomy with wide paratracheal lymph node dissection, thyroidectomy, and tracheotomy should be performed for patients who have high risk factors such as subglottic extension and advanced stage. We believe that tracheotomy should be precede endotracheal intubation. Efforts should be made to prevent stomal recurrence by utilizing postoperative radiotherapy and by minimizing postoperative complications such as infection and fistula.

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