• Journal of Nutrition and Health
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• v.28 no.5
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• pp.451-459
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• 1995

This study was intended to figure out the effects of the amount and the distribution of body fat on the risk fators of adult disease. Sixty-four male college students paticipatied in this study, whose to find out body fat distributions were classified on the basis of Waist/hip ratio(WHR) into three groups-upper body type(UBTM), intermediate body type (IBTM) and lower body type(LBTM). Various risk factors such as adiposity, body fat ammount, serum lipid amount and blood pressure and their intercorrelations were analyzed. The three bodys type groups showed significant differences each other in weight(P<0.001), WHR showed considerable correlations with BMI and the percentage of body fat. The frequency of obesity assessed by BMI$\geq$25 and body fat percentage were the highest in the UBTM of the three groups. Thus, we could conclude that the closer the body fat distribution is to the upper body type, the higher the BMI and body fat percentage. Waist/girth ratio(WTR, P<0.01) and BMI(P<0.05) were positively correlated with serum triglyceride levels, and % of body fat was positively correlated with both serum triglyceride (P<0.01) and serum total cholesterol(P<0.05) levels. WHR (P<0.05), BMI(P<0.01) and % of body fat(P<0.01) also showed positive correlations with systolic blood pressure. From the above results, we could conclude that body fat distribution was a good index reflecting adiposity and body fat amount and that blood and serum amount of triglyceride was highest in the upper body type group showing the highest frequency of obesity.

• Journal of Nutrition and Health
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• v.29 no.7
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• pp.778-787
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• 1996

The purpose of present study was to assess the change of bone mineral density(BMD) and the influences of anthroopometric indices and body composition on BMD in Korean women in Taegu. Subjects were 242 healthy female in the range of 7-67 years old, were divided into 4 age groups in order to assess the influence o factors on BMD according to age. Body composition and BMD measurements of lumbar spine, femur(neck, ward's triangle, trochanter) and total body were performed by dual energy X-ray absorptiometry. The analysis indicated that BMD of most region was positively related to body weight, BMI in all groups 4(50-67years), and closely related to femurs than lumbar spine. This study found correlations between BMD and both total fat body mass and total lean body mass in group 1, 2, 3, and correlations between BMD and only total fat body mass and in group 4. But on regression models the most significant prediction of BMD throughout the skeleton was total lean body mass in group 1(7-16years)and 2(17-34years, and total fat body mass in group 3 and 4. It is concluded that the our data can be used to screen early women of low bone mass. This study confirms that one of the most effective way to prevent osteoporosis and the fractures is to maximize peak bone mass in early life and to minimize bone loss through maintaining adequate weight.

• Journal of Nutrition and Health
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• v.26 no.6
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• pp.715-727
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• 1993

This study was performed to see the effect of nutritional status on fatty liver. Subjects were 219(male : 174, female : 45) fatty liver patients living in cities, and 10-60yrs old. Nutrient and alcohol intakes, health state and medical history were investigated by individual interview, and blood sample was taken. Results were as follow; Most subjects were obese an overweighing and suffering from hepatitis. Calorie and carbohydrate intakes of male and females patients were lower than mean intakes of normal citizens. Protein and fat intakes of male patients were higher than mean intakes of normal citizens. Proportions of protein and fat to total calorie intake in patients were higher than those of normal citizens. Alcohol intake was markedly higher in patients than normal group, and increased with increasing body weight. Serum total cholesterol, HDL-cholesterol, total lipid, total protein and albumin conc.s and Hb and Hct levels were in normal ranges, But serum TG level of patients was higher than normal level. Serum total fatty acid level, $\omega$-3/$\omega$-6 and P/S FA ratios were higher in patients than normals. Serum total EAAs, NEAAs and all AAs levels of patients were higher than normals. It is plausible that high animal food and alcohol intakes, excess body fat and hepatitis were associated with fatty liver.

• Journal of Korean Medicine Rehabilitation
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• v.26 no.2
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• pp.13-28
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• 2016

Objectives To investigate anti-obesity effects of Galgeun-tang, an herbal formula, in high fat diet induced obese mice model. Methods 24 Male C57Bl/6J mice were randomly assigned to normal group fed with normal research diet (NOR, n=6), high fat diet control group treated with water (HFD, n=6), high fat diet group treated with Orlistat (ORL, n=6, Orlistat 10 mg/kg), and high fat diet group treated with Galgeun-tang (GGT, n=6, Galgeun-tang 700 mg/kg). 12 weeks later, body weight, fat weight, liver weight, blood glucose, total cholesterol, triglyceride, HDL, ALT, AST, obesity related neuropeptides and adipokines, ratio of gut microbiota, and histopathology of liver were evaluated. Results In the GGT group, 1. body weight gain, liver weight gain, and total fat weight gain were significantly less than those in the HFD group. 2. blood glucose level was significantly lower and insulin level was significantly higher than in the HFD group. 3. total cholesterol level and triglyceride (TG) level were significantly lower and high density lipoprotein (HDL) level was significantly higher than in the HFD group. 4. appetite-promoting ARC neuropeptides such as Agrp and Npy were significantly less and appetite-inhibiting ARC neuropeptide, Cart was significantly more than in the HFD group in qRT-PCR analysis. 5. adiponectin level and visfatin level were significantly higher, and resistin level and leptin level was significantly lower than in the HFD group. 6. the relative level of Bacteroidetes was significantly higher, and the relative level of Firmicutes was significantly lower than in the HFD group. 7. the increase of adipose tissue was significantly more inhibited than in the HFD group. Conclusions The present study showed that Glageun-tang exerts anti-obesity effects in that it. 1. inhibited the increase in body weight, liver weight, and total fat weight. 2. decreased the level of TG, and increased the level of HDL. 3. influenced neuropeptides and adipokines that are important in regulating food intake and changes of body weight. 4. modified the beneficial quantitative changes in gut microbiota suppressing the tendency toward obesity.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.4
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• pp.73-83
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• 2008

Objectives : In this research, it was investigate that had effects on acupuncture techniques of $HT_{8}$(Shaofu) and $LR_{2}$(Xingjian) acupoints in high fat rats. We recorded data of weight gain, food intake, food efficiency, total cholesterol, triglyceride, AST, ALT, r-GTP, total bilirubin on rats fed high fat diet for 10 weeks. Methods : We divided experimental groups into four. Group of high-fat diet feeding and no treatment was control, group of high-fat diet feeding and acupuncture at $HT_{8}{\cdot}LR_{2}$ was Acu-1, group of high-fat diet feeding and acupuncture at $HT_{8}{\cdot}LR_{2}$ and rotated counter-clockwise 36times was Acu-2, high-fat diet feeding and acupuncture at $HT_{8}$(body direction)${\cdot}LR_{2}$(lower limb direction) and rotated counter-clockwise 36times was Acu-3. Results : In Acu-3 group, body weight on 2 weeks after starting acupuncture, food efficiency and the level of serum total cholesterol were decreased, and the level of HDL-cholesterol was increased. In Acu-1 group, the level of triglyceride was increased but ALT was decreased. Conclusions : These results suggest that treatment of acupuncture at $HT_{8}$(body direction)${\cdot}LR_{2}$(lower limb direction) and rotated counter-clockwise 36times may be having the influence on high fat by controlling the level of serum total cholesterol and HDL-cholesterol.

• Korean Journal of Food Science and Technology
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• v.37 no.5
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• pp.806-811
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• 2005

Effects of green tea-soybean paste on weight-changes and serum lipid profiles in rats fed high fat diet were investigated. Sprague-Barley male rats divided into five groups were fed five different diets for 10 weeks: B group, basal diet H group, high fat-diet containing 0.5% cholesterol+15% lard H-S group, high fat diet containing soybean paste H-0.6GS group, high fat diet containing 0.6% green tea-soybean paste H-4GS group, high fat diet containing 4% green tea-soybean paste. H group showed highest weight gain (p<0.05). Addition of green-tea soybean paste to high-fat diet significantly decreased weight gain, H-4GS group showing highest weight loss (p<0.05). No significant differences in food efficiency ratio and total food intake were found among groups. Liver weight of H group was highest. Addition of green tea-soybean paste to high fat diet significantly reduced liver weight (p<0.05, Table 2). Concentrations of glucose, uric acid, bilirubin, and total protein were similar among all group. Mean GPT values of H-4GS group were significantly different from these of H- and H-S groups (p<0.05). H-S, H-0.6GS, and H-4GS groups had significantly lower triglyceride and total cholesterol, and higher HDL than H-group (p<0,05). H-4GS group had significantly lower serum triglyceride than H-0.6GS group (p<0.05).

• Archives of Pharmacal Research
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• v.14 no.1
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• pp.44-47
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• 1991

Blood lipid levels in rats with high fat-fed hyperlipemia were determined after intraperitoneal administration of a methanolic extract of Prunus davidiana Fr. stems. Administration of the methanolic extract for 6 days produced a significant decrease of blood triglyceride and total cholesterol, and the atherogenic index was also improved. In addition to the hypolipemic effect, the methanolic extract was also shown to be effective in reducing an elevated level of glucose in rats with hyperlipemia resulting from high-fat feeding. On the other hand, blood triglyceride and total cholesterol in rats fed with stock diet were not affected by administration of the methanolic extract even if there was a tendency to decrease. No significant change was also found in the level of glucose. Thus, it is suggested that this methanolic extract probably may increase the metabolic utilization only when fed with excess fat.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.5
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• pp.1147-1151
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• 2008

The purpose of this study was to investigate the effects of Polygonati Rhizoma on the diet-induced hyperlipidemia in rats. Rats were divided into 4 groups, normal group(supplied enough water and feeds only), high fat diet administered group(supplied high fat diet for 4 weeks, Control group) and Astragali Radix administered group(supplied high fat diet and Astragali Radix lyophilization extract for 4 weeks, 397.3 mg/kg(rat) in sample A, 662.5mg/kg(rat) in sample B). Body weight, liver weight and serum lipid levels were evaluated. The water extract of Polygonati Rhizoma decreased body weight, liver weight, total cholesterol, LDL-cholesterol, triglyceride and phospolipid in high fat diet induced hyperlipidemia in rats, and increased HDL-cholesterol.

• The Korean Journal of Physiology
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• v.5 no.1
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• pp.1-9
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• 1971

Body volume, density and %fat were calculated by means of formulas using body height, weight, and surface area in 1,732 children aged between 6 and 12 years. Skinfold thicknesses on back, arm, waist and abdomen were measured by means of a Lange caliper. The course of increase in body volume was identical to those of body height, weight, relative weight and surface area. Curves of boys and girls showed a cross at the age of between 10 and 11 years. Body density of boys increased with the age and it decreased in girls. Total body fat showed a progressive decrease from the age of 6 in boys. In girls body fat increased progressively with the age. Skinfold thickness increased both in boys and girls with the age. At the same age skinfold thicknesses on all sites were greater in girls than boys.

• The Korean Journal of Community Living Science
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• v.17 no.2
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• pp.81-87
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• 2006

This study was made for male and female university students regarding the nutrition knowledge about fat, fat contents in food, and practice toward fat. The result is as follows;1.Out of 13 questions inquiring the knowledge about fat a significant difference was observed between female and male students in 10 questions. Male students' nutrition knowledge about fat was $6.33{\pm}0.16$, and that of female students' was $6.33{\pm}0.16$ and there was no significant difference. The ratio of correct answer was 49% and 59% respectively. Female students marked high ratio of correct answer such items as ${\omega}-3$ fatty acid, the relation between high fat diet and atherosclerosis(coronary disease), the relation between obesity and fat, the relation between ${\omega}-3$ fatty acid and heart disease, cholesterol, fatty acid in butter, degree of unsaturation in liquid oil, margarine, chicken fat, rancity of fat. 2.Male students' total score of knowledge about fat quantity in food was $4.91{\pm}0.10$ and that of female students was $5.58{\pm}0.10$. There was significant difference(p<0.001) and the ratio of correct answer was 55% and 62% respectively. Out of 9 food items, significant difference was observed in 7 items according to student's majoring subject. The ratio of correct answer for the questions about the quantity of fat in food female showed high figures in such items as white meat(p<0.01), whole milk(p<0.0001), skim milk(p<0.01), potato chips(p<0.001), biscuit(p<0.001). However, male students showed high figures on the question about the quantity of fat in vegetable margarine. 3. Out of 12 items observing the degree of diet practice on fat, significant difference was observed between male and female students in 6 items. Female students practice the question items positively with high ratio: intake of fish instead of meat(p<0.01), removing visible fat in meat(p<0.0001), removing chicken skin(p<0.0001), removing oil during cooking (p<0.05), selection of low fat milk or skim milk(p<0.05), selection of meat part(p<0.001). There was significant difference between male and female students in practicing diet on fat (p<0.001) and the total score was $31.52{\pm}0.52$ and $34.65{\pm}0.41$ respectively.