• 대한토목학회논문집
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• 제26권1A호
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• pp.45-54
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• 2006

콘크리트 구조물의 실제적인 응력과 변형률의 관계를 알기 위해서는 크리프와 수축에 관한 구성방정식을 정량화하는 것이 필요하다. 본 연구는 콘크리트의 시간의존적인 변형 중에서 크리프 변형에 관한 현상학적인 문제를 수학적으로 전개하고 유변학적 접근방법을 사용하여 크리프에 관한 예측모델을 구성한다. 고전적인 4-매개변수 모델에 기초하여 각각의 변형성분을 조합하고, 적절한 크리프 변형을 얻어내기 위한 4개의 매개변수들을 재령영향과 겔 입자간의 연결을 제거하려는 미세프리스트레스의 영향을 고려하여 비선형 함수로 구성된 매개변수들을 전개하며 회복이 불가능한 점성변형에 대하여 습윤평형상태와 건조상태에서 모두 예측할 수 있는 유효점성계수를 유도한다. 본 연구에서 제안한 예측모델은 실험결과와 상관계수 99%이상의 우수한 결과를 제공하고 있다.

• 미생물학회지
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• 제21권2호
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• pp.51-60
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• 1983

Cultural characteristics of Strptomyces griseolus isolated from the soil were investigated. This strain was disclosed to utilize D-xylose, and D-glactose in preference order as a carbon source with the formation of glucose isomerase. The addition of sweet potato starch also proved effective promoting the total enzyme activity measured at 29% higher than the control. Corn cob, one of waste agricultural resources, was hydrolyzed in 2~3% $H_2SO_4$ solution at $100^{\circ}C$, 3~5 hours to produce a xylose syrup which gave rise to the recovery of 19.9% in a batch system and 28.2% in a repeated system. By the addition of both 2% of xylose syrup(Be'28) prepared by and us 65% of corn steep liquor (total nitrogen 1.2%), enzyme induction was maximized. The enzyme activity was stimulated by the xylose and the cell growth by the C.S.L. Also, remarkable increase of enzyme activity was noticed by the addition of protein acid hydrolysate 86.2% higher than the control. $QO_2$ of the biomass cultured in 30L capacity jarfermentor recorded low oxygen requirement of 251.2 1/hr. Maximum activity of glucose isomerase was observed noted at the 9th hour after inoculation which is 2 hours faster than the stationery was observed noted at the 9th hour after inoculation which is 2 hours faster than the stationery phase of the biomass growth. Glucose isomerase from the strain was activated by adding the $Co^{++}\;and\;Mg^{++}$ with optimum temperature of $73^{\circ}C$ and pH of 7.2. Conversion ratio of 60% glucose to frutose was 42.5% after 70 hours reaction.

• Architectural research
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• 제11권1호
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• pp.25-33
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• 2009

This study presents the testing of 15 hwangtoh-based cementless concrete mixes to explore the significance and limitations of the development of eco-friendly concrete without carbon dioxide emissions while maintaining various beneficial effects. Hwangtoh, which is a kind of kaolin, was incorporated with inorganic materials, such as calcium hydroxide, to produce a cement-less binder. The main variables investigated were the water-to-binder ratio and fine aggregate-to-total aggregate ratio to ascertain the reliable mixing design of hwangtoh-based cementless concrete. The variation of slump with elapsed time was recorded in fresh concrete specimens. Mechanical properties of hardened concrete were also measured: including compressive strength gain, splitting tensile strength, moduli of rupture and elasticity, stress-strain relationship, and bond resistance. In addition, mechanical properties of hwangtoh-based cement-less concrete were compared with those of ordinary portland cement (OPC) concrete and predictions obtained from the design equations specified in ACI 318-05 and CEB-FIP for OPC concrete, wherever possible. Test results show that the mechanical properties of hwangtoh-based concrete were significantly influenced by the water-to-binder ratio and to less extend by fine aggregate-to-total aggregate ratio. The moduli of rupture and elasticity of hwangtoh-based concrete were generally lower than those of OPC concrete. In addition, the stress-strain and bond stress-slip relationships measured from hwangtoh-based concrete showed little agreement with the design model specified in CEB-FIP. However, the measured moduli of rupture and elasticity, and bond strength were higher than those given in ACI 318-05 and CEB-FIP. Overall, the test results suggest that the hwangtoh-based concrete shows highly effective performance and great potential as an environmental-friendly building material.

• Fisheries and Aquatic Sciences
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• 제14권3호
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• pp.192-197
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• 2011

The objective of this study was to select an effective microbial strain to improve the functional qualities of Eisenia bicyclis water extract by fermentation. For this purpose, several microorganisms isolated from traditional Korean fermented foods were inoculated and cultivated in E. bicyclis water extract. Ultimately, yeast strain YM-1 was selected for further study based on its total phenolic compound (TP) content and antioxidant activity, which were enhanced by microbial fermentation. The extract fermented by YM-1 exhibited a superior TP content and 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity compared to extracts fermented by other microbes. The highest TP content and DPPH radical scavenging activity were observed after one day of YM-1 fermentation. Yeast strain YM-1 was identified as Candida utilis based on an analysis of its physiological characteristics. During fermentation of the extract by C. utilis YM-1, no significant difference was observed in the proximate composition, including moisture, crude lipid, crude protein, and crude ash. Fermentation by C. utilis YM-1 resulted in enhanced biological activity, including increases in the TP content and antioxidant activity. Thus, fermentation by C. utilis YM-1 is an attractive strategy for developing value-added food ingredients.

• 한국식품영양과학회지
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• 제25권5호
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• pp.741-746
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• 1996

대나무잎 추출물을 대상으로 이들을 여러 용매별로 분획하여 동치미 발효에 관여하는 젖산균에 대해 항균활성을 조사하였다. 동치미 담금액 중의 총 균수는 젖산 균수와 발효기간별로 대체적으로 비슷한 양상을 나타내었고 발효 8일째 (equation omitted) a $10^{7}$ CFU/m1로 최고 수치를 나타내었다. 동치미에서 분리한 젖산균을 동정한 결과, BK-02, BK-07 및 BK-22 균주는 Leuconostoc species 로, BK-05와 BK-08 균주는 Lactobaciilus species로, BK-15 균주는 Streptococcus species로 각각 확인되었다. 대나무잎(이대)의 70% ethanol추출물은 BK-02, BK-07, BK-15및 BK-22 균주들에 대해 항균활성을 나타내었으며 특히, BK-22 균주에서 가장 효과가 좋았다. 각 분획별 항균활성은 BK-22 균주가 70% ethanol 분획에서, BK-7 균주가 diethyl ether 분획에서 강하게 나타났으며, 이 두 추출물이 대부분의 분리 균주들에 대해서 항균활성을 나타내었다.

• Journal of Microbiology and Biotechnology
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• 제32권4호
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• pp.437-446
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• 2022

In this study, to obtain icaritin with high pharmacological activities from icariin, which has a content ratio of over 58% in the total flavonoids of Epimedium herb, a special Epimedium flavonoid-glycosidase was produced, purified and characterized from Aspergillus sp.y848 strain. The optimal enzyme production was gained in a medium containing 5% (w/v) wheat bran extract and 0.7% (w/v) Epimedium leaf powder as the enzyme inducer, and strain culture at 30℃ for 6-7 days. The molecular weight of the enzyme was approximately 73.2 kDa; the optimal pH and temperature were 5.0 and 40℃. The enzyme Km and Vmax values for icariin were 15.63 mM and 55.56 mM/h. Moreover, the enzyme hydrolyzed the 7-O-glucosides of icariin into icariside II, and finally hydrolyzed 3-Orhamnoside of icariside II into icaritin. The enzyme also hydrolyzed 7-O-glucosides of epimedin B to sagittatoside B, and then further hydrolyzed terminal 3-O-xyloside of sagittatoside B to icarisiede II, before finally hydrolyzing 3-O-rhamnoside of icarisiede II into icaritin. The enzyme only hydrolyzed 7-O-glucoside of epimedin A or epimedin C into sagittatoside A or sagittatoside C. It is possible to prepare icaritin from the high-content icariin in Epimedium herb using this enzyme. When 2.5% icariin was reacted at 40℃ for 18-20 h by the low-cost crude enzyme, 5.04 g icaritin with 98% purity was obtained from 10 g icariin. Also, the icaritin molar yield was 92.5%. Our results showed icaritin was successfully produced via cost-effective and relatively simple methods from icariin by crude enzyme. Our results should be very useful for the development of medicines from Epimedium herb.

• 한국지반환경공학회 논문집
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• 제13권1호
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• pp.21-29
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• 2012

액상화에 의한 지반 파괴는 지반 진동이 발생하는 도중은 물론이고 지반 진동이 종료된 이후에도 크게 발생할 가능성이 있다. 이러한 지반 변형 혹은 파괴 과정 중에는 지반 내에서 과잉간극수압의 재분배가 일어나고, 그 결과 시시각각 흙의 유효응력이 변화하게 된다. 따라서 지진 후 배수 과정에서는 전체 배수량의 변화뿐만 아니라 배수과정에서 흙의 유효응력 변화특성이 매우 중요하다고 생각된다. 본 연구의 주요한 목적은 다양한 비배수 전단이력을 모래에 가한 후 발생하는 체적압축특성, 즉 체적변형률과 평균유효응력의 관계를 밝히는 것이다. 본 연구에서는 모래의 상대밀도와 반복전단이력을 변화시켜가면서 반복전단 삼축압축시험을 실시하고 그 결과를 액상화 후의 재압축 특성에 초점을 맞추어 분석하였다. 시험 결과 모든 경우에서 평균유효응력이 0이 되는 영역에서 체적변형률의 발생이 급증하는 패턴을 보였으며 세립분을 포함하고 있는 풍화토가 보다 완만한 패턴을 보이고 있었다. 또한 반복재하에 의한 액상화 후의 압축특성은 누적 손실에너지와 최대전단변형률에 크게 의존하고 있으며 이러한 경향은 상대밀도나 재하이력 및 흙의 종류에 관계없이 동일한 경향으로 나타나고 있음을 알 수 있었다. 특히 세립분을 포함하는 모래에서는 누적 손실에너지와 최대체적변형률의 일정한 추세선을 확인할 수 있었으나, 표준사와 같은 입도가 균등한 흙에서는 팽창 특성에 의해 유효응력이 일시적으로 상승하면서 통일성 있는 관계로 파악하기 어려웠다.

• Journal of Nutrition and Health
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• 제30권6호
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• pp.622-633
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• 1997

This study was to investigate the effects of chitin, chitosan , NOCC and cellulose on cadmium toxicity and lipid metabolism in rats. Fifty male rats of Sprague-Dawley strain weighing 155$\pm$17g were divided into 10 groups according to body weight, and were raised for 5 weeks. Levels of 0 and 400 ppm of cadmium chloride were in the diets. And chitin, chitosan , NOCC and cellulose were given at the level of 0 and 4%(w/w) of the diets. Chitosan and NOCC decreased Cd concentration of liver and kidney, and increased the fecal excretion of Cd. Although cellulose was less effective, cellulose also decreased Cd concentration of liver and increased fecal Cd excretion . However chitin had little effect on alleviating Cd toxicity. In addition, chitosan and NOCC lowered total lipid, cholesterol and triglyceride contents in serum and liver by decreasing the lipid absorption. The lowering of cholesterol especially had a remarkable effect. Although it was less effective than chitosan and NOCC, chitin decreased the lipid absorption ratio and lowered cholesterol contents in serum and liver. In conclusion , chitosan and NOCC showed effects of decreasing the absorption of Cd and lipid.

• 한국자원식물학회지
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• 제30권3호
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• pp.311-317
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• 2017

This study was conducted with the aim of evaluating the antibiotic effects of leaves, stems, and roots in yacon (Smallanthus sonchifolius). Antibacterial activity of leaf extract by disk diffusion method with Bacillus subtilis and Escherichia coli respectively showed 13.3 and 13.75mm diameters of clear zone. There was no significant difference between the stems and leaves. The minimum inhibitory concentration of leaves' heating and agitation extraction showed a restrain of strain at 1mg/ml, but the stems and root extract did not appear. Yacon is a functional antibacterial material, and methanol extraction is more effective than water. This research was to investigate the growth stage of collection has the most effective antibacterial effects. It has collected yacon's leaves from June to October, which is an appropriate time for collection right before reaping. Yacon leaf has antibacterial effects on Bacillus subtilis, Escherichia coli, Enterococcus faecium, and Salmonella enteritifis. There were no significant differences by the growth stage of collection. Leaves collected in July are high in phenol which helps in sulfating activity works well considering the high scavenging capability of DPPH. Leaves collected in September are high in total flavonoid.

• International Journal of Concrete Structures and Materials
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• 제10권4호
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• pp.513-525
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• 2016

The resistance-demand approach has emerged as an effective approach for determining the shear capacity of reinforced concrete beams. This approach is based on the fact that both the shear resistance and shear demand are correlated with flexural tensile strain from compatibility and equilibrium requirements. The basic shear strength, under a given loading is determined from the intersection of the demand and resistance curves. This paper verifies the applicability of resistance-demand procedure for predicting the shear capacity of high strength concrete beams without web reinforcement. A total of 18 beams were constructed and tested in four-point bending up to failure. The test variables included the longitudinal reinforcement ratio, the shear span to depth ratio, and the beam depth. The shear capacity of the beams was predicted using the proposed procedure and compared with the experimental values. The results of the comparison showed good prediction capability and can be useful to design practice.