• Journal of KIISE:Software and Applications
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• v.33 no.7
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• pp.589-604
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• 2006

Software product lines (SPL) are recently an emerging software reuse paradigm, which helps organizations develop their products from reusable core assets rather than from scratch. For developing these assets, understanding commonality and variability (C&V) is essential. A feature-oriented approach has been used extensively for C&V analysis in the SPL. However, this contains no proposal to systematically identify features and provide the rationale for the features. Further, the approach does not directly show how the results of C&V analysis will satisfy an organization's high-level business goals and provide the rationale for the C&V. Therefore, this paper presents a domain analysis method for the SPL based on goals, scenarios, and features in order to overcome some of the deficiencies and limitations of the feature-oriented approach. In particular, the paper proposes a domain requirements model (DRM) and a domain requirements modeling method based on the DRM. This method has been applied to the home integration system (HIS) domain to demonstrate its feasibility with a supporting tool, namely IDEAS. Our approach makes it possible to systematically identify the features and provide the rationale for both the features and the C&V.

• Journal of Intelligence and Information Systems
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• v.13 no.1
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• pp.15-27
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• 2007

In Korea, hepatoma is the thirdly frequent cause of death from cancer occupying 17.2% among the whole deaths from cancer and the rate of death from hepatoma comes to about 21's persons per one-hundred thousand ones. This paper proposes an automatic method for the extraction of areas being suspicious as hepatoma from a CT scan and evaluates the availability as an auxiliary tool for the diagnosis of hepatoma. For detecting tumors in the internal of the liver from CT scans, first, an area of the liver is extracted from about $45{\sim}50's$ CT scans obtained by scanning in 2.5-mm intervals starting from the lower part of the chest. In the extraction of an area of the liver, after unconcerned areas outside of the ribs being removed, areas of the internal organs are separated and enlarged by using intensity information of the CT scan. The area of the liver is extracted among separated areas by using information on position and morphology of the liver. Since hepatoma is a hypervascular turner, the area corresponding to hepatoma appears more brightly than the surroundings in contrast-enhancement CT scans, and when hepatoma shows expansile growth, the area has a spherical shape. So, for the extraction of areas of hepatoma, areas being brighter than the surroundings and globe-shaped are selected as candidate ones in an area of the liver, and then, areas appearing at the same position in successive CT scans among the candidates are discriminated as hepatoma. For the performance evaluation of the proposed method, experiment results obtained by applying the proposed method to CT scans were compared with the diagnoses by radiologists. The evaluation results showed that all areas of the liver and liver tumors were extracted exactly and the proposed method has a high availability as an auxiliary diagnosis tools for the discrimination of liver tumors.

• Journal of Embryo Transfer
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• v.28 no.4
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• pp.373-379
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• 2013

Spermatogonial stem cells (SSCs) developed into sperms through spermatogenesis have been utilized as a useful tool in the field of regenerative medicine and infertility. However, a small number of highly qualified SSCs are resided in the seminiferous tubule of testis, resulted in developing effective in-vitro culture system of SSCs for solving simultaneously quantitative and qualitative problems. Presently, SSCs can be enriched on testicular stromal cells (TSCs), but there are no systematic researches about TSC culture. Therefore, we tried to optimize culture condition of TSCs derived from mouse with different strains. For these, proliferation and viability were measured and compared by culturing ICR outbred or DBA/2 inbred mouse-derived TSCs at 35 or $37^{\circ}C$. In case of ICR strain, primary TSCs cultured at $37^{\circ}C$ showed significantly higher proliferation and viability than those at $35^{\circ}C$ and significant increase of proliferation and viability in sub-passaged TSCs was detected in the $35^{\circ}C$ culture condition. Moreover, sub-passage of primary TSCs at $35^{\circ}C$ induced no significant effects on proliferation and viability. In contrast, in case of DBA/2 strain, significantly improved proliferation were detected in the primary TSCs cultured at $35^{\circ}C$, which showed no significant difference in the viability, compared to those at $37^{\circ}C$. Furthermore, sub-passaged TSCs cultured at $37^{\circ}C$ showed no significant differences in proliferation and viability, compared to those at $35^{\circ}C$. However, with significant decrease of proliferation induced by sub-passage of primary TSCs at $35^{\circ}C$, no significant effects on proliferation and viability were resulted from sub-passage of primary TSCs at $37^{\circ}C$. From these results, culture temperature of primary TSCs derived from outbred and inbred strain of mouse could be separately optimized in primary culture and subculture.

• Journal of Navigation and Port Research
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• v.42 no.1
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• pp.25-30
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• 2018

This study was carried out to analyze the risk attitude based on situation awareness of the Vessel Traffic Service Operator (VTSO) on the risk of collision between vessels during the monitoring of vessel traffic through the use of the VTS system. In general, when two vessels are in the close quarters situation, we analyzed the degree of risk of collision from the subjective viewpoint of the VTSOs through an administered survey. Chiefly, we analyzed the risk attitudes of each VTSO in the close quarters situation, by comparing it with the calculated value by the CoRi, which is the ship collision risk model from the VTSO's viewpoint. As a result, it was confirmed that more than 40% of the total VTSO was noted as being in a weak risk aversion type of category. Through a review of the results of analyzing the risk attitude of VTSO according to gender, age, VTS career, VTS center position, accident experience, and boarded career, it was found that there was a significant difference in the VTS career, VTS center position and accident experience. In addition, a regression model that is able to further explain the risk attitude of VTSO was derived as a factor that confirmed the significant difference and applied to CoRi to predict the collision risk according to the individual VTSO to be used as a fundamental information gathering tool for providing more accurate and safe VTS service at sea.

• Journal of KIISE:Software and Applications
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• v.34 no.7
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• pp.635-645
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• 2007

Component technology has been widely accepted as an effective way for building software systems with reusable components, and Microsoft (MS) .NET is one of the recent representative component technologies. Model Driven Architecture (MDA) is a new development paradigm which generates software by transforming design models automatically and incrementally. Transformation of structural models in MDA has been successfully applied. However, transformation of dynamic models and pervasive services, such as transaction service, security service, synchronization service and object pooling are largely remains as an area for further research. The recent enterprise system has multi tier distributed architecture, and the functionality of early mentioned pervasive services is essential for this architecture. .NET platform can implement Component Object Model+ (COM+) component for supporting pervasive services by specify Attribute code. In this paper, we specify the functionalities of the COM+ component offering pervasive services, and then those functionalities are defined by UML profile. By using the profile, the Platform Specific Model (PSM) for .NET/C# is specified, and .NET components are automatically generated through our tool. The development productivity, extensibility, portability, and maintenance of software can be dramatically improved by using of the proposed methods.

• International Journal of Highway Engineering
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• v.12 no.3
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• pp.87-92
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• 2010

As the Concept "how environmental friendly" becomes more and more important in road construction. However, so far there is no estimation method. Environmental friendly concept can be incorporated at the plan level in order to influence decision making, and support policies that affect environment. The overall goal of this study was to develop environmental friendly concept measures for the national highway and to develop a methodology to implement a more environmental friendly concept. The research identified 8 performance measures through a project analysis that could address environmental impact assessment system's ten strategic goals - Topography, Wildlife, hydrology, landuse, air quality, water quality, soil, waste, noise, landscape. The qualitatively and quantitatively evaluation approach was selected as the decision support framework and performance measure were investigated using the AHP(Analytic Hierarchy Process) and pilot corridor for a 10 section and calculate the index values. The methodology was applied to a pilot corridor comprised of a 120km section of national highway in korea. The methodology made it possible to identify the specific performance measures that need improvement to enhance the overall environmental friendly concept. It is fairly intuitive, based on readily available data, and is easy to apply. It provides a powerful tool for government to assess the relative environmental friendly conceptof their transportation corridors now and in the future. It allows for comparisons within a corridor and with other corridors and identifies the improvements needed to enhance the environmental friendly concept.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.328-328
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• 2007

Large area matrix-addressed image detectors are a recent technology for x-ray imaging with medical diagnostic and other applications. The imaging properties of x-ray pixel detectors depend on the quantum efficiency of x-rays, the generated signal of each x-ray photon and the distribution of the generated signal between pixels. In a phosphor coated detector the light signal is generated by electrons captured in the phosphor screen. In our study we simulated the lateral spread distributions for phosphor coupled detector by Monte Carlo simulations. Most simulations of such detectors simplify the setup by only taking the conversion layer into account neglecting behind. The Monte Carlo code MCNPX has been used to simulate the complete interaction and subsequent charge transport of x-ray radiation. This has allowed the analysis of charge sharing between pixel elements as an important limited factor of digital x-ray imaging system. The parameters are determined by lateral distribution of x-ray photons and x-ray induced electrons. The primary purpose of this study was to develop a design tool for the evaluation of geometry factor in the phosphor coupled optical imaging detector. In order to evaluate the spatial resolution for different phosphor material, phosphor geometry we have developed a simulation code. The developed code calculates the energy absorption and spatial distribution based on both the signal from the scintillating layer and the signal from direct detection of x-ray in the detector. We show that internal scattering contributes to the so-called spatial resolution drop of the image detector. Results from the simulation of spatial distribution in a phosphor pixel detector are presented. The spatial resolution can be increased by optimizing pixel size and phosphor thickness.

• The Journal of Korean Physical Therapy
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• v.23 no.1
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• pp.21-28
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• 2011

Purpose: The aim of this study was to investigate correlations between the Functional Movement Screen (FMS), pain, and performance ability in professional fencing players. Methods: Fifty-six athletes participated in this study. The pain group included those who had a score on a pain-related Visual Analogue Scale (VAS) of ${\geq}$20 and an Oswestry Disability Index (ODI) score ${\geq}$10). In the non-pain group, these scores were: VAS(<20), ODI(<10). The VAS and ODI were used to measure pain throughout the study. Performance ability included motor function of the lower extremities (as assessed by a Modified Functional Index Questionnaire, MFIQ), dynamic balance (Balance system, BS and Posture med, PM), flexor and extensor muscle strength of the lumbar region was recorded as maximal isometric strength. Results: Among athletes who had pain, 5 of 15(33.33%) showed impaired functional movement. Conversely, only 2 of 41(4.88%) of those who had no pain showed such impairment (FMS ${\leq}$14score). The athletes who had pain and who had an FMS score above 14 (10/56; 17.86%) showed a significantly higher score for extensor muscle strength of the lumbar compared with those with pain and an FMS score below 14 (5/56; 8.93%) were significant correlations between the FMS and pain (r=-0.40 to -0.42, p<0.01), the MFIQ (r=-0.33, p<0.05), dynamic balance (r=-0.27 to -0.40, p<0.05-0.01), muscle strength of the lumbar (r=0.27 to 0.29, p<0.05). Stepwise multiple regression analysis showed that the dynamic balance score (${\beta}{\beta}$=-0.41) had slightly more power in predicting FMS score than pain, motor function of lower extremity, or muscle strength. Conclusion: The FMS was significantly associated with values of pain, motor function of the lower extremities, dynamic balance, and muscle strength of the lumbar. However the FMS appears to lack relevance and reasonable evidence to suggest that it is an acceptable measurement tool for functional movement analysis.

• Journal of Life Science
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• v.23 no.2
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• pp.290-298
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• 2013

The genus Mycobacterium includes crucial animal and human pathogens such as Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium bovis. Although it is important to understand the genetic basis for their virulence and persistence in host, genetic analysis in mycobacteria was hampered by a lack of sufficient genetic tools. Therefore, many functional vectors as molecular genetic tools have been designed for understanding mycobacterial biology, and the application of these tools to mycobacteria has accelerated the study of mechanisms involved in virulence and gene expression. To overcome the pre-existing problems in genetic manipulation of mycobacteria, this paper reports new vector systems as effective genetic tools in Mycobacterium smegmatis. Three vectors were developed; pKOTs is a suicide vector for mutagenesis containing a temperature-sensitive replication origin (TSRO) and the sacB gene encoding levansucrase as a counterselectable marker. pMV306lacZ is an integrative lacZ transcriptional fusion vector that can be inserted into chromosomal DNA by site-specific recombination. pTnMod-OKmTs is a minitransposon vector harboring the TSRO that can be used in random mutagenesis. It was demonstrated in this study that these vectors effectively worked in M. smegmatis. The vector systems reported here are expected to successfully applicable to future research of mycobacterial molecular genetics.

• Korean Journal of Ecology and Environment
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• v.42 no.1
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• pp.39-47
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• 2009

Spatial and temporal analysis of water quality was performed for eleven monitoring stations in Dongjin River watershed in order to determine the trends of monthly water quality. The monthly water quality data of biochemical oxygen demand (BOD), total nitrogen (TN) and total phosphorus (TP) during $1995{\sim}2004$, were analyzed utilizing Seasonal Mann-Kendall test, LOWESS and three-dimensional graphic approaches. The results indicated that BOD and TN concentrations had the downward trend, but TP showed the upward trend, especially in Gobucheon. This numerical and graphic analysis is the useful tool to analyze the long-term trend of water quality in a large river system.