• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.1C
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• pp.98-104
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• 2009

Tone injection scheme has been known as one of PAPR(Peak to Average Power Ratio) reduction methods deployable to multi-carrier system like OFDM(Orthogonal Frequency Division Multiplexing). The basic idea in tone injection scheme is to enforce the constellation size larger so that each of original constellation points is mapped into the preassigned distinct points. Along the accomplishment of tone injection, it needs great amount of computations to search out not only an appropriate frequency but a phase. Although there is no loss of transmission rate is expected because of no need to send the overhead, the tone injection scheme has not been preferable due to its enormous computations. To alleviate the amount of complexity, this paper proposes the GA(Genetic Algorithm) based tone injection scheme such that its complexity is reduced comparing with that of the conventional method. The simulation results show that the proposed GA based tone injection scheme approaches the PAPR performance associated with the conventional exhaustive search method at the expense of low computations.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.2C
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• pp.217-225
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• 2009

Tone injection scheme has been known as one of peak to average power ratio (PAPR) reduction methods deployable to multi-carrier system like orthogonal frequency division multiplexing (OFDM). The basic idea in tone injection scheme is to enforce the constellation size larger so that each of original constellation points is mapped into the preassigned distinct locations. According to the tone injection scheme, it increases symbol power highly induced inherently by expanding constellation to get optimal PAPR reduction. In the other hand, to get optimal power increase, the PAPR would be reduced insufficiently with limited tone injection signal. To withstand these problems, this paper consider the reduction of the PAPR and power increase problem simultaneously, Toward this, the tone injection scheme accomplished by employing the weighted sum genetic algorithm which has been utilized to solve multi-objective optimization problem (MOOP). The simulation results verifies that the proposed scheme can control the effective PAPR performance and alleviation of power increase flexibly by the weight value at the expense of relatively low complexity.

• The Korean Journal of Physiology and Pharmacology
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• v.9 no.2
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• pp.77-86
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• 2005

In this study, we examined the morphine-induced modulation of the nociceptive spinal dorsal horn neuronal activities before and after formalin-induced inflammatory pain. Intradermal injection of formalin induced time-dependent changes in the spontaneous activity of nociceptive dorsal horn neurons. In naive cats before the injection of formalin, iontophoretically applied morphine attenuated the naturally and electrically evoked neuronal responses of dorsal horn neurons. However, neuronal responses after the formalin-induced inflammation were significantly increased by morphine. Bicuculline, $GABA_A$ antagonist, increased the naturally and electrically evoked neuronal responses of dorsal horn neurons. This increase in neuronal responses due to bicuculline after the formalin-induced inflammation was larger than that in the naive state, suggesting that basal $GABA_A$ tone increased after the formalin injection. Muscimol, $GABA_A$ agonist, reduced the neuronal responses before the treatment with formalin, but not after formalin treatment, again indicating an increase in the GABAergic basal tone after the formalin injection which saturated the neuronal responses to GABA agonist. Morphine-induced increase in the spinal nociceptive responses after formalin treatment was inhibited by co-application of muscimol. These data suggest that formalin-induced inflammation increases $GABA_A$ basal tone and the inhibition of this augmented $GABA_A$ basal tone by morphine results in a paradoxical morphineinduced increase in the spinal nociceptive neuronal responses after the formalin-induced inflammation.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.11C
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• pp.1076-1084
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• 2009

We propose an ATI (Adaptive Tone Injection) scheme based on clipping noise for PAPR (Peak-to-Average Power Ratio) reduction of OFDM (Orthogonal Frequency Division Multiplexing) signals. The proposed scheme is composed of three steps: clipping, tone selection, and TI procedures. In the first step, the peak samples in the IFFT (Inverse Fast Fourier Transform) outputs are scaled down by clipping. In the second step, the sub-carrier position where the power of the clipping noise is the maximum, is selected. Finally, the generic TI procedure is performed. Simulation results show that the proposed scheme does not require all the possible combinations of the original TI procedures, while maintaining the PAPR reduction performance.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.622-627
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• 2008

Experiment of active noise control on supersonic jet noise was conducted by use of microjet injection. The microjets were injected to the shear layer of the main jet through 22 small holes at the lip of a rectangular nozzle. Based on the measurement of farfield sound pressure, it was found that the jet noise was effectively reduced by several dB(in some cases up to 10 dB). The power levels of all measurement points were also reduced by use of microjet injection. The microjet affected not only the broadband noise but also the screech tone noise. The sound pressure level, the frequency of the screech tone, and the structure of the jet could be changed by the microjet. Flow visualization with schlieren technique was also made to observe the effect of microjet on the flow field.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.9
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• pp.4502-4517
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• 2019

Tone Injection (TI) scheme significantly reduces the peak-to-average power ratio (PAPR) of Multicarrier Modulation (MCM). However, the computational complexity of the TI scheme rises exponentially with the extra freedom constellation number. Therefore, a novel immune evolutionary mechanism-based TI scheme is proposed in this paper to reduce the computational complexity. By restraining undesirable degeneracy during the processing, this IEM scheme can dramatically increase the population fitness. Monte Carlo results show that proposed IEM-based TI scheme can achieve a significant PAPR and BER improvement with a low complexity.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.13 no.10
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• pp.998-1004
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• 2002

This paper reports a design of feedforward linear power amplifier using pilot tone for IMT-2000 band repeaters accepting multi-carrier. As this time pilot tone is applied to the circuit differently from the existing method. Only one pilot tone is used in both 1-st loop(IMD abstraction loop) and 2-nd loop(IMD cancellation loop) to cancell IMD signals automatically according to variation of frequency or power level of input signals. As an experiment, in range of 2110 MHz - 2170 MHz at LPA output power of $20 W_{avg}$, IMD characteristics of over 20 dB was improved maintaining below -60 dBc considering respective 20 MHz. Therefore the supposed feedforward linear power amplifier can be used for linear power amplifier in IMT-2000 band repeaters.

• Journal of Korean Neurosurgical Society
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• v.29 no.6
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• pp.719-724
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• 2000

Objectives : It has been reported that the presence of a pharmacologically inactive foreign substance, polystyrene latex bead, in subarachnoid space activates a non-specific immunological response and elicits arterial narrowing. Recently the activation of potassium($K^+$) channels may be of benefit in relieving cerebral vasospasm. The present study examined the effects of systemic administration of a ATP-sensitive $K^+$ channel activator, cromakalim, on the polystyrene latex bead-induced cerebral vasospasm. Methods : The spasm models similar to that caused by subarachnoid blood injection were created by injection of bead into rabbit cisterna magna. Intravenous injections of cromakalim were administered twice daily(bid) 30 minutes after induction of vasospasm. Animals were killed by perfusion-fixation 2 days after vasospasm. Basilar arteries were removed and sectioned, and the luminal cross-sectional areas were measured. Results : Injection of bead elicited an arterial constriction, reducing arterial diameter to 33.3% of resting tone. Cromakalim inhibited bead-induced constriction at a dose of 0.3mg/kg(Mann-Whitney test, p<0.01). Conclusion : These results support the concept that the cellular events triggered by inactivation of ATP-sensitive $K^+$ channels are responsible for the pathogenesis of vasospasm. The findings also indicate that cromakalim represents a potential therapeutic agents for the treatment of cerebral vasospasm.

• Korean Journal of Audiology
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• v.24 no.1
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• pp.24-28
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• 2020

Background and Objectives: Systemic steroid therapy (SST) and intratympanic steroid injection (ISI) have been the treatment of choice for sudden sensorineural hearing loss (SSNHL). We studied the effect of ISI administered at different intervals on hearing outcomes in patients with SSNHL. Subjects and Methods: We performed a retrospective study of 427 patients diagnosed with SSNHL at Bundang Jesaeng Hospital, of whom 51 patients with SSNHL who received SST and four ISIs were included in this study. Patients were treated with four ISIs either every day for 4 days (group 1) or at intervals (mean duration of interval: 2.21 days) (group 2). Hearing outcomes were evaluated using the pure-tone test before the injection and 14 days, 1 month, and 3 months after the final injection. Recovery rates were classified based on Siegel's criteria. Results: The amount of improvement was 27.67 dB (±20.45) in group 1 and 32.79 dB (±21.42) in group 2. However, there were no significant differences between the two groups (p= 0.714). The recovery rates based on Siegel's criteria were 18/27 (66.7%) and 16/24 (66.7%) in groups 1 and 2, respectively, with no significant difference (p=1.000). Considering only complete recoveries in hearing recovery, the recovery rates were 15/27 (55.6%) and 14/24 (58.3%) in groups 1 and 2, respectively, with no significant difference (p=0.842). Conclusions: There were no significant differences in hearing outcomes or recovery rates after ISI administration every day or at intervals of 2-3 days.

• Journal of Audiology & Otology
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• v.24 no.1
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• pp.24-28
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• 2020

Background and Objectives: Systemic steroid therapy (SST) and intratympanic steroid injection (ISI) have been the treatment of choice for sudden sensorineural hearing loss (SSNHL). We studied the effect of ISI administered at different intervals on hearing outcomes in patients with SSNHL. Subjects and Methods: We performed a retrospective study of 427 patients diagnosed with SSNHL at Bundang Jesaeng Hospital, of whom 51 patients with SSNHL who received SST and four ISIs were included in this study. Patients were treated with four ISIs either every day for 4 days (group 1) or at intervals (mean duration of interval: 2.21 days) (group 2). Hearing outcomes were evaluated using the pure-tone test before the injection and 14 days, 1 month, and 3 months after the final injection. Recovery rates were classified based on Siegel's criteria. Results: The amount of improvement was 27.67 dB (±20.45) in group 1 and 32.79 dB (±21.42) in group 2. However, there were no significant differences between the two groups (p= 0.714). The recovery rates based on Siegel's criteria were 18/27 (66.7%) and 16/24 (66.7%) in groups 1 and 2, respectively, with no significant difference (p=1.000). Considering only complete recoveries in hearing recovery, the recovery rates were 15/27 (55.6%) and 14/24 (58.3%) in groups 1 and 2, respectively, with no significant difference (p=0.842). Conclusions: There were no significant differences in hearing outcomes or recovery rates after ISI administration every day or at intervals of 2-3 days.