• 한국군사과학기술학회지
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• 제14권1호
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• pp.114-122
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• 2011

In this paper, we have identified the system instability factors in a bistatic radar system using pulse chasing and considered their effects on the bistatic receiver's MTI(Moving Target Indication) improvement performance. The pulse chasing is a method to efficiently scan a restricted search area within the limited transmitter power and time in a bistatic radar and to track a series of transmitted pulses using the receiver beam which has ideally matched to the pulse propagation rate. In this paper, we have discussed the interrelationship between the pulse chasing and time and frequency/phase synchronization and described the effects of the identified system instability factors on two kinds of MTI filter configuration, single delay-line and double delay-line, in the bistatic radar. And also, we have confirmed that the overall system improvement is restricted by a lower improvement factor among identified them, and discussed the allowable tolerance of the time and frequency/phase synchronization in the bistatic system.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2004년도 학술대회지
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• pp.190-197
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• 2004

In order to consider statistical properties of probability variables used in the structural analysis, the conventional approach using the safety factor based on past experience usually estimated the safety of a structure. Also, the real structures could only be analyzed with the error in estimation of loads, material characters and the dimensions of the members. But the errors should be considered systematically in the structural analysis. In this paper, we estimated the probability of failure of the pressure vessel. And also, this paper presents sensitivity values of the random variable. Finally, we show that reliability index and probability of failure can present the tolerance limit of dimension of randam variables.

• 상하수도학회지
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• 제12권2호
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• pp.127-139
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• 1998

The objectives of this study is at the development of the channel routing model which can be used for flood prediction. Among the routing models, the hydraulic technique of the implicit scheme in the dynamic equation is selected to route the unsteady varied flow in the open channel. The channel routing model is catchment runoff which computed by the conceptual and transfer function model. The conceptual and transfer function model can simulate the catchment runoff accurately. As a result of investigating the channel routing model, the optimal weighting factor ${\theta}$ which fixes two points between time line is chosen, and also, the optimal error tolerance which satisfies computing time and converge of solution is determined in this study.

• 원예과학기술지
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• 제33권4호
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• pp.575-584
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• 2015

건조 스트레스는 작물의 생존과 생산성을 결정하는데 매우 중요한 환경요인이다. 본 연구의 목적은 배추에서 신규 건조 스트레스 저항성 유전자를 동정 검정하는 것이다. 건조 스트레스 하에서 생육된 지부('Chiifu') 배추를 이용하여 제작된 KBGP-24K 마이크로어레이 데이터 분석을 통해 738개의 건조 반응 유전자 중 기능은 밝혀져 있지 않지만, 건조 스트레스 하에서 발현량이 6배 이상 크게 증가한 1개의 유전자를 선발하여 BrDSR(B. rapa Drought Stress Resistance)이라 명명하였다. 이의 검정을 위해 내혼계배추('CT001')에서 BrDSR을 동정한 결과 438bp의 오픈리딩프레임과 145개의 아미노산을 가지고 있음을 확인하였고, 동정된 완전장의 cDNA 염기서열은 형질전환용 과발현 vector인 'pSL100' 제작에 이용하였다. BrDSR이 식물체에서 건조 스트레스 저항성을 향상시켜줄 수 있는지 분석하기 위해 담배 형질전환을 수행하였다. PCR과 DNA 블롯 분석으로 선발된 T1 세대 담배 형질전환체들을 대상으로 quantitative real-time RT PCR 분석을 수행한 결과, 형질전환체의 BrDSR 발현량은 비형질 전환체 보다 2.6배까지 증가하였다. 또한 건조처리 10일째 수행한 표현형 분석에서 BrDSR이 발현되는 담배 형질전환체들이 비형질전환체들 보다 우수한 건조 저항성을 보였다. 연구 결과들을 종합하면 BrDSR은 건조 스트레스 하에서 식물의 생장과 생존에 효과적인 저항성 기능을 할 것으로 기대된다.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.77.2-78
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• 2003

An EREBP/AP2-type transcription factor (CaPFl) was isolated by DDRT-PCR following inoculation of soybean pustule pathogen Xanthomonas axonopodis pv. glycines Bra which induces HR on pepper leaves. Genomic Southern blot analysis revealed that the CaPFl gene is present as a single copy within the hot pepper genome. The deduced amino acid sequence of CaPFl has two potential nuclear localization signals, a possible acidic activation domain, and an EREBP/AP2 motif that could bind to a conserved cis- element present in promoter region of many stress-induced genes. The mRNA level of CaPFl was induced by both biotic and abiotic stresses. We observed higher-level transcripts in resistance-induced pepper tissues than diseased tissues. Expression of CaPFl is also induced upon various abiotic stresses including ethephon, MeJA, cold stress, drought stress and salt stress treatments. To study the role of CPFI in plant, transgenic Arabidopsis and tobacco plants which express higher level of pepper CaPFl were generated. Global gene expression analysis of transgenic Arabidopsis by cDNA microarray indicated that expression of CaPFl in transgenic plants affect the expression of quite a few GCC box and DRE/CRT box-containing genes. Furthermore, the transgenic Arabidopsis and tobacco plant, expressing CaPFl showed tolerance against freezing temperature and enhanced resistance to Pseudomonas syrnigae pv. tabaci. Taken together, these results indicated that CaPFl is a novel EREBP/AP2 transcription factor in hot pepper plant and it may has a significant role(s) in regulation of biotic and abiotic stresses in plant.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6267-6271
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• 2013

Objective: To determine clinical efficacy, safety and prognostic factors of pemetrexed plus platinum as first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). Materials and Methods: Clinical characteristics, short-term efficacy, survival and adverse reactions of 47 advanced non-squamous NSCLC patients who had received pemetrexed plus platinum as first-line treatment in Shanghai Pulmonary Hospital from January 2009 to June 2011 were retrospectively analyzed. The Chi-squared test was applied to statistically analyze the overall response rate (ORR), disease control rate (DCR) and toxicity reactions in both groups, while survival data wereanalyzed by Kaplan-Meier and logrank methods, and the COX proportional hazards model was adopted for a series of multi-factor analyses. Results: Only two patients were lost to follow-up. The ORR, DCR, medium progression-free survival time (PFS) and medium overall survival (OS) were 31.9%, 74.5%, 5 months and 15.2 months, while 1- and 2-year survival rates were 63.8% (30/47) and 19.2% (9/47), respectively. Single-factor analysis showed that tumor pathological patterns and efficacy were in association with medium PFS (P<0.05), whereas tumor pathological patterns, smoking history and efficacy were closely connected with medium OS (P<0.05). Multi-factor analyses demonstrated that pathological patterns and efficacy were independent factors influencing OS (P<0.05). The rate of toxicity reactions in degree III/IV was low, including hematologic toxicity marked by decline in white blood cell count and decrease in the platelet count (PLT), and non-hematologic toxicity manifested by gastrointestinal reactions, such as nausea and vomiting. Conclusions: Pemetrexed plus platinum as first-line treatment has excellent efficacy and slight adverse reactions with favorable drug-tolerance in patients with advanced non-squamous NSCLC.

• Safety and Health at Work
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• 제7권4호
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• pp.307-316
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• 2016

Background: Resilience engineering (RE) is a new paradigm that can control incidents and reduce their consequences. Integrated RE includes four new factors-self-organization, teamwork, redundancy, and fault-tolerance-in addition to conventional RE factors. This study aimed to evaluate the impacts of these four factors on RE and determine the most efficient factor in an uncertain environment. Methods: The required data were collected through a questionnaire in a petrochemical plant in June 2013. The questionnaire was completed by 115 respondents including 37 managers and 78 operators. Fuzzy data envelopment analysis was used in different ${\alpha}$-cuts in order to calculate the impact of each factor. Analysis of variance was employed to compare the efficiency score means of the four abovementioned factors. Results: The results showed that as ${\alpha}$ approached 0 and the system became fuzzier (${\alpha}=0.3$ and ${\alpha}=0.1$), teamwork played a significant role and had the highest impact on the resilient system. In contrast, as ${\alpha}$ approached 1 and the fuzzy system went toward a certain mode (${\alpha}=0.9$ and ${\alpha}=1$), redundancy had a vital role in the selected resilient system. Therefore, redundancy and teamwork were the most efficient factors. Conclusion: The approach developed in this study could be used for identifying the most important factors in such environments. The results of this study may help managers to have better understanding of weak and strong points in such industries.

• 성인간호학회지
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• 제28권4호
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• pp.399-414
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• 2016

Purpose: The purpose of this study was to review and identify factors relevant to workplace bullying in nursing. Methods: Twenty-three studies that met the criteria were selected from a sample of twenty-six studies. These articles were retrieved from a central literature databases (N=13,241). The total correlational effect size (ESr) for each related factor was calculated from Fisher's Zr. A funnel plot inspection (similar to scatter plot) with a trim-and-fill method was used to assess the publication bias of the meta-analyzed studies. Results: From the systematic review, fifty-one factors were identified as having an influencing effect. Fourteen factors (five individual and nine organizational factors) were eligible for meta-analysis. The individual factors included, self-esteem (ESr=-.31), psychological capital (ESr=-.26), and marital status (ESr=-.06) which were significantly correlated with workplace bullying. Organizational factors included, organizational tolerance (ESr=.48), supervisor incivility (ESr=.47), job stress (ESr=.46), group morale (ESr=-.36), group support (ESr=-.35), supervisor leadership (ESr=-.35), group identity (ESr=-.33), and structural empowerment (ESr=-.27). These factors were significantly correlated with workplace bullying. There were no publication biases except for both individual and organizational factors. Conclusion: Organizational factors have more of an greater impact than individual factors on workplace bullying. The results of this study support the need for intervention at the organizational level.

• Earthquakes and Structures
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• 제10권6호
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• pp.1331-1346
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• 2016

Historical masonry structures have an important value for cultures and it is essential for every society to strengthen them and confidently transfer to the future. For this reason, determination of the seismic earthquake response, which is the most affecting factor to cause the damage at these structures, gain more importance. In this paper, the seismic earthquake behaviour of Kaya Çelebi Mosque, which is located in Turkey and the restoration process has still continued after 2011 Van earthquake, is determined. Firstly the dynamic modal analysis and subsequently the seismic spectral analysis are performed using the finite element model of the mosque constructed with restoration drawings in SAP2000 program. Maximum displacements, tensile, compressive and shear stresses are obtained and presented with contours diagrams. Turkish Earthquake Code and its general technical specifications are considered to evaluate the structural responses. After the analyses, it is seen that the displacements and compressive/shear stresses within the code limits. However, tension stresses exceeded the maximum values at some local regions. For this mosque, this is in tolerance limits considering the whole structure. But, it can be said that the tension stresses is very important for this type of the structures, especially between the stone and mortar. So, some additional strengthening solutions considering the originality of historical structures may be applicable on maximum tensile regions.

• 한국공작기계학회논문집
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• 제17권5호
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• pp.70-75
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• 2008

This paper describes a tool-clamping/unclamping mechanism for application of a micro-spindle. The mechanism is based on one-way shape memory effect and interference-fit. The corresponding mathematical models and a few considerable design parameters are mentioned in this paper. Especially, necessary conditions for the clamping and unclamping operation are investigated through finite element analysis. The analysis results show that the differences between the diametral deformations of the tool holder in high temperature and that in low temperature are increased according to amounts of the interference. Thus the less interference between the tool-holder and the ring, the less tolerance to allow the clamping and unclamping operation because the inner diameter of the tool holder in high temperature should be smaller than the diameter of the tool shank, and that in low temperature should be larger than the diameter of the tool shank. In addition, the design for maximization of clamping force are investigated based on finite element analysis. The results show that the more amounts of the interference, the more clamping force. As the result, the interference should be considered as a important factor to maximize the tool clamping force.