• Title/Summary/Keyword: Tobias

Search Result 52, Processing Time 0.019 seconds

Optomechanical Design and Structure Analysis of Prototype Siderostat for Testing Local Volume Mapper Telescope Control System

  • Lee, Sunwoo;Han, Jimin;Ahn, Hojae;Kim, Changgon;Yang, Mingyeong;Ji, Tae-geun;Lee, Sumin;Kim, Taeeun;Pak, Soojong;Konidaris, Nicholas P.;Drory, Niv;Froning, Cynthia S.;Hebert, Anthony;Bilgi, Pavan;Blanc, Guillermo A.;Lanz, Alicia E.;Hull, Charles L;Kollmeier, Juna A.;Ramirez, Solange;Wachter, Stefanie;Kreckel, Kathryn;Pellegrini, Eric;Almeida, Andr'es;Case, Scott;Zhelem, Ross;Feger, Tobias;Lawrence, Jon;Lesser, Michael;Herbst, Tom;Sanchez-Gallego, Jose;Bershady, Matthew A;Chattopadhyay, Sabyasachi;Hauser, Andrew;Smith, Michael;Wolf, Marsha J;Yan, Renbin
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.46 no.1
    • /
    • pp.38.4-39
    • /
    • 2021
  • The Local Volume Mapper (LVM), for the Sloan Digital Sky Survey V, consists of four 16 cm telescopes with three fiber spectrographs in the Las Campanas Observatory in Chile. With the fixed telescopes on optical tables, the Alt-Alt mounted siderostats point and guide targets during spectrograph exposures. We are developing the integrated LVM instrument control software. Considering international travel restrictions caused by the COVID-19 pandemic in 2021, we decided to make a simplified version of siderostat to test the LVM telescope control system in Korea. The prototype siderostat consists of two aluminum flat mirrors, optomechanical housing structures made by aluminum profiles, and the Planewave L-350 mount. We designed the optical mirrors and the optomechanical structure of the siderostat. From structural analysis at various pointing cases, we estimated the tilt misalignments of mirrors within 4 arcsec, which would affect the telescope pointing errors.

  • PDF

Quantification of Pancreas Surface Lobularity on CT: A Feasibility Study in the Normal Pancreas

  • Riccardo Sartoris;Alberto Calandra;Kyung Jin Lee;Tobias Gauss;Valerie Vilgrain;Maxime Ronot
    • Korean Journal of Radiology
    • /
    • v.22 no.8
    • /
    • pp.1300-1309
    • /
    • 2021
  • Objective: To assess the feasibility and reproducibility of pancreatic surface lobularity (PSL) quantification derived from abdominal computed tomography (CT) in a population of patients free from pancreatic disease. Materials and Methods: This retrospective study included 265 patients free from pancreatic disease who underwent contrast-enhanced abdominal CT between 2017 and 2019. A maximum of 11 individual PSL measurements were performed by two abdominal radiologists (head [5 measurements], body, and tail [3 measurements each]) using dedicated software. The influence of age, body mass index (BMI), and sex on PSL was assessed using the Pearson correlation and repeated measurements. Inter-reader agreement was assessed using the intraclass correlation coefficient (ICC) and Bland Altman (BA) plots. Results: CT images of 15 (6%) patients could not be analyzed. A total of 2750 measurements were performed in the remaining 250 patients (143 male [57%], mean age 45 years [range, 18-91]), and 2237 (81%) values were obtained in the head 951/1250 (76%), body 609/750 (81%), and tail 677/750 (90%). The mean ± standard deviation PSL was 6.53 ± 1.37. The mean PSL was significantly higher in male than in female (6.89 ± 1.30 vs. 6.06 ± 1.31, respectively, p < 0.001). PSL gradually increased with age (r = 0.32, p < 0.001) and BMI (r = 0.32, p < 0.001). Inter-reader agreement was excellent (ICC 0.82 [95% confidence interval 0.72-0.85], with a BA bias of 0.30 and 95% limits of agreement of -1.29 and 1.89). Conclusion: CT-based PSL quantification is feasible with a high success rate and inter-reader agreement in subjects free from pancreatic disease. Significant variations were observed according to sex, age, and BMI. This study provides a reference for future studies.

Bile acid sequestrants in poor healing after endoscopic therapy of Barrett's esophagus

  • Lukas Welsch;Andrea May;Tobias Blasberg;Jens Wetzka;Elisa Muller;Myriam Heilani;Mireen Friedrich-Rust;Mate Knabe
    • Clinical Endoscopy
    • /
    • v.56 no.2
    • /
    • pp.194-202
    • /
    • 2023
  • Background/Aims: Endoscopic therapy for neoplastic Barrett's esophagus (BE) has become the standard of care over the past two decades. In clinical practice, we regularly encounter patients who fail to achieve complete squamous epithelialization of the esophagus. Although the therapeutic strategies in the individual stages of BE, dysplasia, and esophageal adenocarcinoma are well studied and largely standardized, the problem of inadequate healing after endoscopic therapy is only marginally considered. This study aimed to shed light on the variables influencing inadequate wound healing after endoscopic therapy and the effect of bile acid sequestrants (BAS) on healing. Methods: Retrospective analysis of endoscopically treated neoplastic BE in a single referral center. Results: In 12.1% out of 627 patients, insufficient healing was present 8 to 12 weeks after previous endoscopic therapy. The average follow-up duration was 38.8±18.4 months. Complete healing was achieved in 13 patients already after intensifying proton pump inhibitor therapy. Out of 48 patients under BAS, 29 patients (60.4%) showed complete healing. An additional eight patients (16.7%) improved, but only partial healing was achieved. Eleven (22.9%) patients showed no response to BAS augmented therapy. Conclusions: In cases of insufficient healing even under exhaustion of proton pump inhibitors, treatment with BAS can be an option as an ultimate healing attempt.

Measuring the severity of close encounters between ringed small bodies and planets

  • Jeremy Wood;Jonti Horner;Tobias C Hinse;Stephen C Marsden
    • Monthly Notices of the Royal Astronomical Society
    • /
    • v.480 no.3
    • /
    • pp.4183-4198
    • /
    • 2018
  • Rings have recently been discovered around the trans-Neptunian object (TNO) 136108 Haumea and the Centaur 10199 Chariklo. Rings are also suspected around the Centaur 2060 Chiron. As planetary close encounters with ringed small bodies can affect ring longevity, we previously measured the severity of such encounters of Chariklo and Chiron using the minimum encounter distance, dmin. The value of dmin that separates noticeable encounters from non-noticeable encounters we called the 'ring limit', R. R was then approximated as 10 tidal disruption distances, 10Rtd. In this work, we seek to find analytical expressions for R that fully account for the effects of the planet mass, small body mass, ms, ring orbital radius, r, and velocity at infinity, v, for fictitious ringed Centaurs using ranges 2 × 1020 kg ≤ms≤ 1 Pluto mass and 25 000 ≤r ≤ 100 000 km. To accomplish this, we use numerical integration to simulate close encounters between each giant planet and ringed Centaurs in the three-body planar problem. The results show that R has a lower bound of approximately 1.8Rtd. We compare analytical and experimental R values for a fictitious Haumea, Chariklo, and Chiron with r= 50 000 km. The agreement is excellent for Haumea, but weaker for Chariklo and Chiron. The agreement is best for Jupiter and Saturn. The ring limits of the real Haumea, Chariklo, and Chiron are <4Rtd. Experimental R values for the fictitious bodies make better approximations for the R values of the real bodies than does 10Rtd. Analytical values make good first approximations.

Retrospective long-term analysis of bone level changes after horizontal alveolar crest reconstruction with autologous bone grafts harvested from the posterior region of the mandible

  • Voss, Jan Oliver;Dieke, Tobias;Doll, Christian;Sachse, Claudia;Nelson, Katja;Raguse, Jan-Dirk;Nahles, Susanne
    • Journal of Periodontal and Implant Science
    • /
    • v.46 no.2
    • /
    • pp.72-83
    • /
    • 2016
  • Purpose: The goal of this study was to evaluate the long-term success of horizontal alveolar crest augmentation of the retromolar region of the mandible with particulated bone, as well as factors affecting subsequent peri-implant bone loss. Methods: A total of 109 patients (68 female, 41 male) suffering from alveolar ridge deficiencies of the maxilla and mandible were included in this study. All patients were treated with particulated retromolar bone grafts from the mandible prior to the insertion of endosseous dental implants. Mesial and distal peri-implant crestal bone changes were assessed at six time points. Several parameters, including implant survival and the influence of age, gender, localisation of the implant, diameter, covering procedures, and time points of implant placement, were analysed to identify associations with bone level changes using the Mann-Whitney U-test, the Kruskal-Wallis test, and Spearman's rank-order correlation coefficient. Results: A total of 164 dental implants were placed in the maxilla (n=97) and in the mandible (n=67). The mean observation period was $105.26{\pm}21.58$ months after implantation. The overall survival rate was 97.6% after 10 years. Overall, peri-implant bone loss was highest during the first year, but decreased over time. The mean amount of bone loss after 10 years was 2.47 mm mesially and 2.50 mm distally. Bone loss was significantly influenced by implant type and primary stability. Conclusions: The use of particulated autologous retromolar bone grafts is a reliable technique for the horizontal reconstruction of local alveolar ridge deficiencies. Our results demonstrate that implants placed in augmented bone demonstrated similar bone level changes compared to implants inserted in non-augmented regions.

Detection of Clavibacter michiganensis subsp. michiganensis Assisted by Micro-Raman Spectroscopy under Laboratory Conditions

  • Perez, Moises Roberto Vallejo;Contreras, Hugo Ricardo Navarro;Herrera, Jesus A. Sosa;Avila, Jose Pablo Lara;Tobias, Hugo Magdaleno Ramirez;Martinez, Fernando Diaz-Barriga;Ramirez, Rogelio Flores;Vazquez, Angel Gabriel Rodriguez
    • The Plant Pathology Journal
    • /
    • v.34 no.5
    • /
    • pp.381-392
    • /
    • 2018
  • Clavibacter michiganensis subsp. michiganesis (Cmm) is a quarantine-worthy pest in $M{\acute{e}}xico$. The implementation and validation of new technologies is necessary to reduce the time for bacterial detection in laboratory conditions and Raman spectroscopy is an ambitious technology that has all of the features needed to characterize and identify bacteria. Under controlled conditions a contagion process was induced with Cmm, the disease epidemiology was monitored. Micro-Raman spectroscopy ($532nm\;{\lambda}$ laser) technique was evaluated its performance at assisting on Cmm detection through its characteristic Raman spectrum fingerprint. Our experiment was conducted with tomato plants in a completely randomized block experimental design (13 plants ${\times}$ 4 rows). The Cmm infection was confirmed by 16S rDNA and plants showed symptoms from 48 to 72 h after inoculation, the evolution of the incidence and severity on plant population varied over time and it kept an aggregated spatial pattern. The contagion process reached 79% just 24 days after the epidemic was induced. Micro-Raman spectroscopy proved its speed, efficiency and usefulness as a non-destructive method for the preliminary detection of Cmm. Carotenoid specific bands with wavelengths at 1146 and $1510cm^{-1}$ were the distinguishable markers. Chemometric analyses showed the best performance by the implementation of PCA-LDA supervised classification algorithms applied over Raman spectrum data with 100% of performance in metrics of classifiers (sensitivity, specificity, accuracy, negative and positive predictive value) that allowed us to differentiate Cmm from other endophytic bacteria (Bacillus and Pantoea). The unsupervised KMeans algorithm showed good performance (100, 96, 98, 91 y 100%, respectively).

Towards Routine Clinical Use of Radial Stack-of-Stars 3D Gradient-Echo Sequences for Reducing Motion Sensitivity

  • Block, Kai Tobias;Chandarana, Hersh;Milla, Sarah;Bruno, Mary;Mulholland, Tom;Fatterpekar, Girish;Hagiwara, Mari;Grimm, Robert;Geppert, Christian;Kiefer, Berthold;Sodickson, Daniel K.
    • Investigative Magnetic Resonance Imaging
    • /
    • v.18 no.2
    • /
    • pp.87-106
    • /
    • 2014
  • Purpose : To describe how a robust implementation of a radial 3D gradient-echo sequence with stack-of-stars sampling can be achieved, to review the imaging properties of radial acquisitions, and to share the experience from more than 5000 clinical patient scans. Materials and Methods: A radial stack-of-stars sequence was implemented and installed on 9 clinical MR systems operating at 1.5 and 3 Tesla. Protocols were designed for various applications in which motion artifacts frequently pose a problem with conventional Cartesian techniques. Radial scans were added to routine examinations without selection of specific patient cohorts. Results: Radial acquisitions show significantly lower sensitivity to motion and allow examinations during free breathing. Elimination of breath-holding reduces failure rates for non-compliant patients and enables imaging at higher resolution. Residual artifacts appear as streaks, which are easy to identify and rarely obscure diagnostic information. The improved robustness comes at the expense of longer scan durations, the requirement for fat suppression, and the nonexistence of a time-to-center value. Care needs to be taken during the configuration of receive coils. Conclusion: Routine clinical use of radial stack-of-stars sequences is feasible with current MR systems and may serve as substitute for conventional fat-suppressed T1-weighted protocols in applications where motion is likely to degrade the image quality.

Carcass characteristics of lambs fed spineless cactus as a replacement for sugarcane

  • de Oliveira, Juliana Paula Felipe;Ferreira, Marcelo de Andrade;Alves, Adryanne Marjorie Souza Vitor;de Melo, Ana Caroline Cerqueira;de Andrade, Ida Barbosa;Urbano, Stela Antas;Suassuna, Juraci Marcos Alves;de Barros, Leonardo Jose Assis;Melo, Tobias Tobit de Barros
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.31 no.4
    • /
    • pp.529-536
    • /
    • 2018
  • Objective: Fresh sugarcane has been a new roughage source for ruminant's in semiarid regions, a function of the decline of sugar and alcohol industry in recent years. However, there is little data published regarding lambs fed sugarcane associated with spineless cactus. This study evaluated the effect of sugarcane replacement with spineless cactus (0%, 33%, 66%, and 100%) in the diet of Santa $In\hat{e}s$ lambs on carcass characteristics. Methods: Thirty-six non-castrated Santa Ines lambs at four months of age and an initial body weight of $22{\pm}2.3kg$ were assigned in a randomized block design and slaughtered after 70 days of confinement. The effects of spineless cactus as a replacement for sugarcane in the diet of the lambs on the carcass characteristics, commercial cut weight and yield, leg tissue composition, and carcass measurements were studied. Results: The study revealed quadratic behavior in slaughter body weight, and hot and cold carcass weight, with maximum values of 38.60, 18.60, and 18.11 kg and replacement levels of 40.18%, 44.42%, and 43.14%, respectively. The cold carcass yield presented an increasing linear behavior. The compactness index of carcass and leg presented a quadratic effect, with estimated maximal values of 0.28 and 0.57 kg/cm and replacement levels of 43.37% and 45.5%, respectively. The weights of commercial cuts of leg, loin, shoulder, and breast showed quadratic behavior, with maximum values of 2.79, 0.852, 1.46, and 1.30 kg and replacement levels of 49.5, 45.32, 39.0, and 40.7, respectively. For tissue composition, quadratic behavior was verified for leg weight, subcutaneous fat, and total fat. Conclusion: The replacement of sugarcane by spineless cactus at level 44% is recommended for finishing lambs considering that this level improved most of the carcass characteristics, weights, and yields of commercial cuts and leg tissue composition.

Towards 3D Modeling of Buildings using Mobile Augmented Reality and Aerial Photographs (모바일 증강 현실 및 항공사진을 이용한 건물의 3차원 모델링)

  • Kim, Se-Hwan;Ventura, Jonathan;Chang, Jae-Sik;Lee, Tae-Hee;Hollerer, Tobias
    • Journal of the Institute of Electronics Engineers of Korea CI
    • /
    • v.46 no.2
    • /
    • pp.84-91
    • /
    • 2009
  • This paper presents an online partial 3D modeling methodology that uses a mobile augmented reality system and aerial photographs, and a tracking methodology that compares the 3D model with a video image. Instead of relying on models which are created in advance, the system generates a 3D model for a real building on the fly by combining frontal and aerial views. A user's initial pose is estimated using an aerial photograph, which is retrieved from a database according to the user's GPS coordinates, and an inertial sensor which measures pitch. We detect edges of the rooftop based on Graph cut, and find edges and a corner of the bottom by minimizing the proposed cost function. To track the user's position and orientation in real-time, feature-based tracking is carried out based on salient points on the edges and the sides of a building the user is keeping in view. We implemented camera pose estimators using both a least squares estimator and an unscented Kalman filter (UKF). We evaluated the speed and accuracy of both approaches, and we demonstrated the usefulness of our computations as important building blocks for an Anywhere Augmentation scenario.

Influence of wound closure on volume stability with the application of different GBR materials: an in vitro cone-beam computed tomographic study

  • Naenni, Nadja;Berner, Tanja;Waller, Tobias;Huesler, Juerg;Hammerle, Christoph Hans Franz;Thoma, Daniel Stefan
    • Journal of Periodontal and Implant Science
    • /
    • v.49 no.1
    • /
    • pp.14-24
    • /
    • 2019
  • Purpose: To assess the influence of using different combinations of guided bone regeneration (GBR) materials on volume changes after wound closure at peri-implant dehiscence defects. Methods: In 5 pig mandibles, standardized bone defects were created and implants were centrally placed. The defects were augmented using different combinations of GBR materials: xenogeneic granulate and collagen membrane (group 1, n=10), xenogeneic granulate and alloplastic membrane (group 2, n=10), alloplastic granulates and alloplastic membrane (group 3, n=10). The horizontal thickness was assessed using cone-beam computed tomography before and after suturing. Measurements were performed at the implant shoulder (HT0) and at 1 mm (HT1) and 2mm (HT2) below. The data were statistically analysed using the Wilcoxon signed-rank test to evaluate within-group differences. Bonferroni correction was applied when calculating statistical significance between the groups. Results: The mean horizontal thickness before suturing was $2.55{\pm}0.53mm$ (group 1), $1.94{\pm}0.56mm$ (group 2), and $2.49{\pm}0.73mm$ (group 3). Post-suturing, the values were $1.47{\pm}0.31mm$ (group 1), $1.77{\pm}0.27mm$ (group 2), and $2.00{\pm}0.48mm$ (group 3). All groups demonstrated a loss of horizontal dimension. Intragroup changes exhibited significant differences in group 1 (P<0.001) and group 3 (P<0.01). Intergroup comparisons revealed statistically significant differences of the relative changes between groups 1 and 2 (P=0.033) and groups 1 and 3 (P=0.015). Conclusions: Volume change after wound closure was minimized by using an alloplastic membrane. The stability of the augmented horizontal thickness was most ensured by using this type of membrane irrespective of the bone substitute material used for membrane support.