• Asian Pacific Journal of Cancer Prevention
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• 제17권11호
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• pp.5005-5009
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• 2016

Introduction: Gutkha contains harmful and carcinogenic chemicals and oral cancer caused by tobacco usage has been reported as a major preventable cause of death worldwide by the World Health Organization. The Telangana state government implemented a ban on gutkha usage starting in 2013 but how effective this ban has been remains unclear. Objectives: The objective of this study was to determine the actual impact of the gutkha ban on users and vendors. Methodology: A cross-sectional study was conducted among gutkha users and tobacco vendors in Ranga Reddy district, Telangana. Based on a pilot study the sample size was determined as 368 and 384 for users and vendors respectively. Two separate questionnaires were administered to these groups. The parameters studied mainly included knowledge regarding the ban, and its impact. Results: About 49.1% of the users were aware of the ban on gutkha. Newspapers were the main source of information regarding the ban as reported by 45.3% of users. After the ban, 29.8% of gutkha users switched to other tobacco products. Awareness of health hazards and non-availability of gutkha was the most important reason stated for quitting or reducing consumption. Conclusion: The perspective of ban when visualized from the users point of view depicted a negative impact while the vendors portrayed a positive impact. Considering the addictive potential of the ingredients of gutkha, recording the effects of the ban on regular consumers and determining whether they can still obtain the products by illicit trade, would be noteworthy for implementation of strict rules.

• 한국학교보건학회지
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• 제19권2호
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• pp.75-88
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• 2006

Purpose : This study are the secondary data of Global Youth Tobacco Survey(GYTS) developed by the WHO and United State Center for Disease Control(CDC) and Prevention to trace tobacco use among youth in youth in countries across the world. This study was carried out to serve for a basis for antismoking campaigns and to prevent adolescents from smoking by analyzing the smoking by analyzing the smoking realities factors. Methods : This study is a cross-sectional school-based survey, which employed a two-stage cluster sample design to produce a nationally representative sample of middle school students aged 13 to 15 years olds. Seventy-five schools were selected. All schools containing grade 1, 2 and 3 that contained 40 or students were included in the sampling frame. Results : The results of this study were as follows ; 1. The proportion of smoking students in middle school was 6.4% and the rate of smoking in male students(7.4%) was higher than it of in female students(5.5%). 2. 26.5% of all respondent had a experience to try smoke and the results showed that the rate of trying smoking in male students was increased by grade more than female students. 3. According to test of significance in regression analysis, the independent variables such as sex, school grade, smoking parents, friends distinction, pocket money and others showed statistical significance. 4. There was a statistical significance between smokers and nonsmokers in proportion to the completing the preventive education for nonsmoking(p=0.0023) and the acquirement of knowledge on smoking(p<.0001). 5. Finally there was a statistical significance between the exposure to anti-smoking campaign(p=0.0053) and tobacco advertisement in the mass media and the smoking(p=0.0036). Conclusion : All things considered, the health education for tobacco control in school need to be developed from an elementary school. I suggest that prevent smoking program in school need to be revitalized and be made more accessible for everyone who wish to quit. And the government should develop the regulation on total banning promoting cigarette advertising and smoking scene in the movie for young people.

• Journal of Microbiology and Biotechnology
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• 제23권6호
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• pp.771-778
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• 2013

Essential oils are increasingly of interest for use as novel drugs acting as antimicrobial and antiviral agents. In the present study, we report the in vitro antiviral activities of 29 essential oils, extracted from Chinese indigenous aromatic plants, against the tobacco mosaic virus (TMV). Of these essential oils, those oils from ginger, lemon, tea tree, tangerine peel, artemisia, and lemongrass effected a more than 50% inhibition of TMV at 100 ${\mu}g/ml$. In addition, the mode of antiviral action of the active essential oils was also determined. Essential oils isolated from artemisia and lemongrass possessed potent inactivation and curative effects in vivo and had a directly passivating effect on TMV infection in a dose-dependent manner. However, all other active essential oils exhibited a moderate protective effect in vivo. The chemical constitutions of the essential oils from ginger, lemon, tea tree, tangerine peel, artemisia, and lemongrass were identified by gas chromatography and gas chromatography-mass spectrometry. The major components of these essential oils were ${\alpha}$-zingiberene (35.21%), limonene (76.25%), terpinen-4-ol (41.20%), limonene (80.95%), 1,8-cineole (27.45%), and terpinolene (10.67%). The curative effects of 10 individual compounds from the active essential oils on TMV infection were also examined in vivo. The compounds from citronellal, limonene, 1,8-cineole, and ${\alpha}$-zingiberene effected a more than 40% inhibition rate for TMV infection, and the other compounds demonstrated moderate activities at 320 ${\mu}g/ml$ in vivo. There results indicate that the essential oils isolated from artemisia and lemongrass, and the individual compound citronellal, have the potential to be used as an effective alternative for the treatment of tobacco plants infected with TMV under greenhouse conditions.

• 분석과학
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• 제28권1호
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• pp.1-7
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• 2015

4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco specific nitrosamine found only in tobacco products. The ability to monitor biomarker concentrations is very important in understanding environmental tobacco smoke (ETS). In this study, an efficient and sensitive method for the analysis of NNK in dust was developed and validated using liquid chromatography tandem mass spectrometry. Dust was collected with filter paper soaked in methanol. The standard solution and dust sample were diluted with 100 mM ammonium acetate and extracted using dichloromethane. Our calibration curves ranged from 25 to $10^4pg/mL$. Excellent linearity was obtained with correlation coefficient values between 0.9996 and 1.0000. The limit of detection (LOD) was 5 pg/mL ($S/N{\geq}3$) and the retention time was 10 min. The limit of quantification (LOQ) was 25 pg/mL, and the acceptance criteria was the rate of 98-103% (80-120% at levels up to $3{\times}LOQ$). The coefficient of variations (CV) was 2.8%. Accuracies determined from dust samples spiked with four different levels of NNK racurves ranged that from 25 to 104 pg/mL. Excellent linearity was obtained between 92.1% and 114%. The precision of the method was acceptable (5% of CV). The recovery rates of the whole analytical procedure at low, medium, and high levels were 105.7-116.5% for NNK. The carry-over effects during LC-MS/MS analysis were not observed for NNK. This manuscript summarizes the scientific evidence on the use of markers to measure ETS.

• 한국토양비료학회지
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• 제47권3호
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• pp.217-224
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• 2014

Ground-based remote sensing can be used as one of the non-destructive, fast, and real-time diagnostic tools for predicting yield, biomass, and nitrogen stress during growing season. The objectives of this study were: 1) to assess biomass and nitrogen (N) status of tobacco (Nicotiana tabacum L.) plants under N stress using ground-based remote sensors; and 2) to evaluate the feasibility of spectral reflectance indices for estimating an application rate of N and predicting yield of tobacco. Dry weight (DW), N content, and N uptake at the 40th and 50th day after transplanting (DAT) were positively correlated with chlorophyll content and normalized difference vegetation indexes (NDVIs) from all sensors (P<0.01). Especially, Green NDVI (GNDVI) by spectroradiometer and Crop Circle-passive sensors were highly correlated with DW, N content and N uptake. The yield of tobacco was positively correlated with canopy reflectance indices measured at each growth stage (P<0.01). The regression of GNDVI by spectroradiometer on yield showed positively quadratic curve and explained about 90% for the variability of measured yield. The sufficiency index (SI) calculated from data/maximum value of GNDVI at the $40^{th}$ DAT ranged from 0.72 to 1.0 and showed the same positively quadratic regression with N application rate explaining 84% for the variability of N rate. These results suggest that use of reflectance indices measured with ground-based remote sensors may assist in determining application rate of fertilizer N at the critical season and estimating yield in mid-season.

• 한국연초학회지
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• 제17권1호
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• pp.27-32
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• 1995

A new flue-cured tobacco mutant line BU 8832-85 was developed at Taegu Experiment Station, Korea Ginseng and Tobacco Research Institute in 1994. KF 8832-85 was resulted from a cross of flue-cured cultivars NC 95$\times$NC 2326, and developed by a pedigree system of breeding ; initial selection was made by plant type and resistance to bacterial wilt(BW) disease(heudomonas solanaceamm) in the F2 generation under the natural field conditions infested with the pathogen. One white flowered plant was occurred by spontaneous mutation in a certain line among the F3 generatioin while the others were pink. Six plants from the seeds by selfing were selected at the field infested with the pathogen among 240 populations with white flowering in the F4, KF 8832-85 was selected based on yield and leaf quality trials among 6 lines in Fs generation. BCF 8832-85 was compared with its Parent for certain agronomic and chemical characteristics at Taegu Experiment Station in 1993 and 1994. The results showed that KF 8832-85 have white flower, the stalk height was approximately that of NC 2326 but averaged about loom taller than NC 95. It produced ground suckers as much as NC 95, and did not breakdown leaf at the same as WC 2326. KF 8832-85 have high resistance to bacterial wilt disease. Yield of KF 8832-85 was 10 and 18% higher then that of NC 2326 and WC 95, respectively. Price per Kg was equal to that of NC 2326. The contents of nicotine and reducing sugar did not differ significantly from NC 95, while total nitrogen was significantly lower than NC 95. Therefore, the new mutant line is genetically stable for agronomic and chemical characteristics and provides a source of bacterial wilt disease resistance for use in breeding resistant flue-cured cultivars. Key words : Mutant line, White flower, Spontaneous mutation.

• 한국응용곤충학회지
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• 제9권2호
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• pp.91-94
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• 1970

1. 담배 야화병은 비교적 기온과 습도가 낮은 $(18-20^{\circ}C,\; 65-75\%)$, 6월 상순부터 중순에 걸쳐 발생하기 시작했으며 기온과 습도가 점차 높아지는 $(22-26^{\circ}C,\;65-68\%)$ 6월 하순에서 7월 상순 사이에 더욱 빠른속도로 발달했고 7월 중순 이후 8월에 걸친 계절적인 폭풍우가 답배의 잎에 기계적 상해를 줌으로써 야화병의 감염을은 최대로 증가됨을 볼 수 있었다. 2. 약제처리로서는 히도마이신 300-350 배액을 발병기에 2-3회 살포한 것이 가장 효과적이어서 결과적으로 감염율을 $28.3\%$까지 감소시켰다. 3. 크로르피크린에 의한 이식전 토양 처리 (10l/10a)는 기타 병해의 방제를 겸해서 본 병의 피해를 월등히 감소시켰으며 본 포에서의 e담배 생육 상태에도 무처리구에 비해 왕성하였다. 4. 이상의 실험예서 담배 야화병의 효과적인 방제는 조기재배에 의한 수확기의 단축과 6월 상순에서 중순까지의 발병기에 적절한 약제의 살포 그리고 이식전의 토양처리 등을 함으로써 이룩될 수 있다고 본다.

• 생명과학회지
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• 제34권5호
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• pp.320-332
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• 2024

본 연구는 연소담배와 비교해 서로 다른 가열담배(heated tobacco products, HTPs) 사용 시 혈역학적 지표들의 급성 반응을 비교하고, 급성 HTPs 에어로졸 노출이 심장 자율신경조절(cardiac autonomic regulation, CAR)에 미치는 영향을 탐색하려는 목적으로 수행되었다. 또한, 서로 다른 연초 스틱 간 급성 심혈관 효과의 비교 검증을 목표로 하위연구를 설계했다. 외관상 건강한 남성 흡연자 16명은 개방표지, 무작위 교차시험으로, 최소 48시간 세척기간과 함께 비-흡연(non-smoking, NS), 담배 흡연 및 서로 다른 두 가지 HTPs 사용 세션을 각각 수행했다. 하위연구는 NS와 함께 서로 다른 두 가지 연초 스틱 간 급성 심혈관 효과를 비교하기 위해, 참여자 중 8명을 대상으로 실시되었다. 수축기와 확장기 혈압 및 CAR을 반영하는 심박변이도(heart rate variability, HRV)가 각 세션 시작 전, 제품 사용 중 그리고 사용 후 30분까지 평가되었다. NS 동안 혈역학적 변화는 통계적 차가 없었으나, HTPs 에어로졸에 급성 노출은 담배 연기와 상응하는 수축기와 확장기 혈압의 유의한 증가를 초래했으며, 이들 지표에서 HTPs 기기 간 통계적 차는 없었다. 연소담배와 HTPs 사용 후 통계적으로 유의한 심장 교감신경활동(cardiac sympathetic nerve activity, CSNA)의 급성 증가와 심장 미주신경 긴장도(cardiac vagal tone, CVT)의 급격한 저하가 나타났다. 사용 기기와 독립적으로 HTPs 사용에 따른 CSNA와 CVT 반응은 연소담배와 통계적 차가 없었다. 서로 다른 두 가지 연초 스틱은 NS와 비교해 혈역학적 지표들의 유의한 증가를 유도했으나, 연초 스틱 간 통계적 차는 없었다. CVT는 두 가지 연초 스틱 사용에 따라 유의하게 감소했으며, 연초 스틱의 종류에 따라 CVT 저하에 통계적 차가 있었다. 이상의 결과들은 HTPs 에어로졸 노출이 사용 기기와 독립적으로 연소담배와 동등한 급성 심혈관 효과를 유도할 수 있으며, 연초 스틱의 종류에 따라 급성 CAR 저하가 강화될 수 있음을 시사한다.

• 한국산학기술학회논문지
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• 제21권1호
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• pp.247-257
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• 2020

대학생 흡연자가 중증고도 흡연자로 진입하는 것을 차단하고자 여러 가지 금연서비스를 지원하고 있지만 대학생의 금연시도율은 다른 연령대의 금연시도율보다 낮은 수준을 보인다. 본 연구는 대학생의 6개월 금연 성공과 관련된 변수를 도출하여 분석하는 데 그 목적이 있다. 연구 자료는 2015년 6월부터 2016년 12월까지 대전금연지원센터에서 제공하는 금연지원서비스를 이용한 대학생 781명에 대한 자료를 국가금연지원센터로부터 제공받아 분석에 활용하였다. 분석 결과, 4주, 12주, 24주 금연성공률에 모두 유의한 변수는 호기 중 일산화탄소 농도와 금연상담횟수였다. 호기 중 일산화탄소 농도가 10ppm 미만인 사람이 10ppm 이상인 사람보다 금연에 성공할 확률이 4주 2.53배, 12주 2.33배, 24주 2.13배 높은 것으로 나타났다. 상담횟수의 경우, 상담횟수 1회 증가 당 4주, 12주, 24주 각각의 OR은 12.39, 13.13, 12.21로 나타났다. 본 연구는 대학생을 대상으로 금연 중재의 효과성을 높이기 위해 금연 상담 횟수를 향상시키는 것이 필요함을 제안한다.

• 대한간호학회지
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• 제36권1호
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• pp.144-150
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• 2006

Purpose: This study was conducted to 1) find out the characteristic of smoke related characteristics of nurses. 2) find out the frequency of Smoking cessation intervention delivered by nurses. 3) compare the differences in mean scores of smoking cessation interventions by general characteristics. Method: The survey questionnaire was mailed out to nurses who were working at the randomly selected hospitals throughout the country from November 28, 2003 to February 15, 2004. Result: $0.6\%$ of nurses were current smokers $40.7\%$ of nurses have attended smoking cessation education. Nurses who were older, had masters degree, had oncology experience, higher position, participated in smoking cessation education, and had smoking related disease among family members were variables related to higher frequencies in delivering tobacco interventions. Conclusion: Although nurses are in an important position in delivering tobacco interventions and provide resources, their participation in consistent delivery of an intervention is less than desirable. To help nurses to participate in the assessment of tobacco use and interventions for cessation, the development of educational program is necessary.