• 보건교육건강증진학회지
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• 제28권2호
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• pp.41-50
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• 2011

Objectives: Objectives: The objective of this study is to describe the WHO-CHOICE(World Health Organization- CHOosing Interventions that are Cost-Effective) programme, and to consider the application of WHO-CHOICE programme in Korea, especially on the health promotion policy. Methods: Literature review was conducted on the contents of WHO-CHOICE programme in the previous studies, guidebook, and software. We also contacted WHO-CHOICE team at WHO to identify the contents not clearly presented in the documents. Results: The WHO-CHOICE programme is a standardized tool for analyzing and comparing the cost effectiveness of health promotion policies. It is composed of PopMod to measure the health effect of intervention and of CostIt to measure the cost. The cost of tobacco control policy in Korea was analyzed with the cooperation of WHO-CHOICE team preliminary, and the results were different with the results of tobacco control policy on western pacific region of WHO. Conclusions: The cost effectiveness study based on WHO-CHOICE programme could help decide a priority of health promotion policy for settings with limited resources. For the improvement of health, the future work on WHO-CHOICE programme need to be considered.

• 한국연초학회지
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• 제35권1호
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• pp.56-61
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• 2013

Bryonia alba L. belongs to the Cucurbitaceae family and grows in Europe, Asia, America, Africa, Russia, Ukraina and Armenia. The root of Bryonia alba has been used for neuropsychical diseases, psychosis, hysteria, paralysis, epilepsy, vertigo, headache, migrain, melancholia, forgetfulness, sadness, absent mindedness, delirium, cardiovascular disease, ischemia, gastrointestinal diseases, gastric ulcer and respiratory diseases. The root of Bryonia alba contains an oxidized tetra cyclic triterpens, cucurbitaceous, polyunsaturated hydrocarbons, phospholipids, phosphatidylcholines, ethereal oils, fatty acids, a great amount of amino acids, alcohol soluble enzymes, sugar, carotene, vitamin C and E. Bryonia alba increases coronary blood-flow and the amplitude of cardiac contractions. Bryonia alba has an antistressor action and increases the working capacity. Bryonia alba activates connective tissue cells. Bryonia alba markedly increases the oxygen consumption by young and senescent rat brain, liver as well as heart mitochondrial fraction as Korean Ginseng. Bryonia alba decreases lipid peroxidation after immobilization stress. In conclusion, Bryonia alba like Ginseng used in traditional medicine came from ancient time has a good perspective administration as prophylactic and medical remedy, as remedy of lot of diseases in modern medicine.

• 한국연초학회지
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• 제31권1호
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• pp.58-67
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• 2009

Biomarkers could be critical and useful tools for assessing the biological effects of smoking and detecting differences between potentially reduced exposure product (PREP) and conventional cigarettes. Smoking-related biomarkers can be classified into three categories as biomarkers of exposure, biomarkers of effects, and biomarkers of potential harm. When compared with the biomarkers of effects or harm, the biomarkers of exposure for chemical constituents of cigarette smoke are well established and characterized. In addition, they could offer the important information in understanding how cigarette smoke interacts with biological molecules and causes the disease to human. Therefore, we provide an overview of 6 biomarkers of exposure (Nicotine and nicotine metabolites, Carboxyhaemoglobin, NNAL (4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanol) and NNAL - glucuronide, 3-Hydroxypropyl-mercapturic acid, and Monohydroxy-butenyl-mercapturic acids, and Urine mutagenicity) which were validated through extensive research and clinical experience. These reliable biomarkers could help identify the efficacy of PREP by predicting early toxicological effects and lead to improve it.

• 식물병연구
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• 제7권3호
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• pp.170-174
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• 2001

시판고추 종자로부터 Tobamovirus를 검출하고 Tobamovirus 오염률을 조사하고자 gelatin particle agglutination test (GPAT)의 최적조건을 조사하였다. Gelatin 입자에 감작할 담배 모자이크 바이러스 고추 계통에 대한 ${\gamma}$-globulin G 의 최적농도는 100$\mu\textrm{g}$/$m\ell$이었고, GPAT의 바이러스 검출 감도는 효소면역항체법 및 dot immuno-binding assay와 유사하였으며, Tobamovirus 검출을 위한 종자시료의 최적 희석배수는 5배에서 25배였다. 그리고 최적화된 GPAT에 의한 국내시판 고추종자의 Tobamovirus 오염률은 평균 79.1%인 것으로 판명되었다.

• 한국직업건강간호학회지
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• 제28권3호
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• pp.156-165
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• 2019

Purpose: The purpose of this study was to compare working condition and health status between parcel delivery workers (PDW) and food delivery workers (FDW) and to examine the factors influencing their health status. Methods: This was a secondary analysis of data collected from the fifth Korean Working Conditions Survey (KWCS). Based on existing literature, a set of variables was chosen from the KWCS. Results: The proportion of PDW who carryied/moved heavy loads and experienced high job stress and lack of rest time was significantly higher than that of FDW. However, more FDW than their counterparts worked atypical hours. The differences in fatigue and well-being between PDW and FDW were not statistically significant. The multiple logistic regression analysis revealed low temperature, tobacco smoke, standing for long periods, and job stress were significant predictors of fatigue or well-being of FDW. Among PDW, noise, tobacco smoke, sitting for long periods, quantitative demands, hiding emotions, support from colleagues, job stress, no recovery period, and night work were significant predictors of fatigue or well-being. Conclusion: The findings of this study may be useful in developing nursing interventions for disease protection health promotion of delivery workers.

• 치위생과학회지
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• 제17권6호
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• pp.487-494
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• 2017

본 연구는 국민건강영양조사 제4기와 제5기(2007년~2012년) 자료를 이용하였으며, 구강검진 조사자료가 제공되지 않은 2011년 자료를 제외하고, 20세 이상의 성인 11,643명을 대상으로 연도별 흡연 유형별 치주질환의 추이를 살펴보고, 치주질환에 영향을 주는 인자를 평가하였다. 5개년도를 통합한 자료에서는 비흡연자에 비해 직접흡연자는 단순, 다중 로지스틱 회귀분석 모두에서 치주질환이 있을 aOR이 1.78, 1.77이었으며(p<0.001), 연도별 경향성을 보았을 때, 여자에 비해 남자가 치주질환이 있을 aOR은 1.12로 나타났다(p<0.001). 연도별 흡연 유형에 따라 치주질환 유병률은 치주질환이 있는 집단에서 직접흡연자의 비율이 현저하게 증가추세를 보였다. 또한 주요인자를 보정한 연도별 흡연 유형과 치주질환의 관련성을 단변량 분석한 결과, 비흡연자에 비해 직접흡연자의 치주질환이 있을 aOR은 2007년도에 1.99로 가장 높게 나타났다. 반면에 간접흡연자가 비흡연자에 비해 치주질환이 있을 확률은 통계적으로 유의하지 않았다. 인구사회학적 변수와 임상적 변수를 보정한 다변량 로지스틱 분석결과, 2007년도를 제외하고는 치주질환 발생에 있어 직접흡연자의 위험비는 통계적으로 모두 유의하였다. 반면 치주질환 발생에 있어 간접흡연의 영향력은 2010년도에서만 1.68의 aOR로 통계적 유의성을 보였다(p=0.032). 결론적으로 본 연구를 통해 연도에 따라 간접흡연의 노출이 증가되고 있음을 간접적으로 예측할 수 있었고, 직접흡연자에 비해 통계적 영향력의 크기는 뚜렷하지 않지만 치주질환에 있어 위험인자로서 독립적으로 고려되어야 함을 확인할 수 있었다. 중대구강병인 치주질환의 다양한 위험요인을 규명하고, 이를 예방하기 위한 측면에서 간접흡연과 치주질환의 명확한 기전과 영향력 크기를 밝히기 위한 근거자료 마련이 지속화되어야 할 것이다.

• Journal of Microbiology and Biotechnology
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• 제17권1호
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• pp.130-137
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• 2007

A disease resistance related gene, MbR7, was identified in the wild apple species, Malus baccata. The MbR7 gene has a single open reading frame (ORF) of 3,288 nucleotides potentially encoding a 1,095-amino acid protein. Its deduced amino acid sequence resembles the N protein of tobacco and the NL27 gene of potato and has several motifs characteristic of a TIR-NBS-LRR R gene subclass. Ectopic expression of MbR7 in Arabidopsis enhanced the resistance against a virulent pathogen, Pseudomonas syringae pv. tomato DC3000. Microarray analysis confirmed the induction of defense-related gene expression in 35S::MbR7 heterologous Arabidopsis plants, indicating that the MbR7 gene likely activates a downstream resistance pathway without interaction with pathogens. Our results suggest that MbR7 can be a potential target gene in developing a new disease-resistant apple variety.

• 농업과학연구
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• 제40권2호
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• pp.93-99
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• 2013

The disease and insect were surveyed locally in greenhouse, fruit packing house and store house of 51 farms in 13 towns having purpose of paprika exportation. By analysis, various disease and insect were not only founded locally but more ones detected in farms having old facilities and no natural enemy. We found 15 pathogens such as Fusarium spp., Alternaria solani, Leveilluila taurica, PepMV (Pepino mosaic virus) and TMV (Tobacco mosaic virus) in greenhouse, Fusarium spp. in fruit packing house and Penicillium spp. in store house. We found 15 insects in greenhouse such as Bemisia tabaci, rialeurodes vaporariorum and Myzus persicae in greenhouse, Hylobitelus haroldi in fruit packing house. However, the problem quarantine disease and insect for importation and exportation were not detected in inspection time.

• The Plant Pathology Journal
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• 제28권1호
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• pp.68-74
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• 2012

Biocontrol microbes have mainly been screened among large collections of microorganisms $via.$ nutrient-rich $in$ $vitro$ assays to identify novel and effective isolates. However, thus far, isolates from only a few genera, mainly spore-forming bacilli, have been commercially developed. In order to isolate field-effective biocontrol microbes, we screened for more than 200 oligotrophic bacterial strains, isolated from rhizospheres of various soil samples in Korea, which induced systemic resistance against the soft-rot disease caused by $Pectobacterium$ $carotovorum$ SCC1; we subsequently conducted in $planta$ bioassay screening. Two oligotrophic bacterial strains were selected for induced systemic disease resistance against the $Tobacco$ $Mosaic$ $Virus$ and the gray mold disease caused by $Botrytis$ $cinerea$. The oligotrophic bacterial strains were identified as $Pseudomonas$ $manteilii$ B001 and $Bacillus$ $cereus$ C003 by biochemical analysis and the phylogenetic analysis of the 16S rRNA sequence. These bacterial strains did not exhibit any antifungal activities against plant pathogenic fungi but evidenced several other beneficial biocontrol traits, including phosphate solubilization and gelatin utilization. Collectively, our results indicate that the isolated oligotrophic bacterial strains possessing induced systemic disease resistance could provide useful tools as effective biopesticides and might be successfully used as cost-effective and preventive biocontrol agents in the field.

• The Plant Pathology Journal
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• 제28권4호
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• pp.364-372
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• 2012

Xanthomonas oryzae pv. oryzae causing bacterial leaf blight disease in rice produces and secretes Hpa1 protein that belongs to harpin protein family. Previously it was reported that Hpa1 induced defense responses when it was produced in tobacco. In this study, we expressed hpa1 gene in rice and Arabidopsis to examine the effects of Hpa1 expression on disease resistance to both fungal and bacterial pathogens. Expression of hpa1 gene in rice enhanced disease resistance to both X. oryzae pv. oryzae and Magnaporthe grisea. Interestingly, individual transgenic rice plants could be divided into four groups, depending on responses to both pathogens. hpa1 expression in Arabidopsis also enhanced disease resistance to both Botrytis cineria and Xanthomonas campestris pv. campestris. To examine genes that are up-regulated in the transgenic rice plants after inoculation with X. oryzae pv. oryzae, known defense-related genes were assessed, and also microarray analysis with the Rice 5 K DNA chip was performed. Interestingly, expression of OsACS1 gene, which was found as the gene that showed the highest induction, was induced earlier and stronger than that in the wild type plant. These results indicate that hpa1 expression in the diverse plant species, including monocot and dicot, can enhance disease resistance to both fungal and bacterial plant pathogens.