• 제목/요약/키워드: Tissue damage

검색결과 1,155건 처리시간 0.031초

안면 외상에서 연부조직 치료에 있어 미용적 재건 (Aesthetic soft tissue management in facial trauma)

  • 정규진;김태곤;이진호
    • 대한의사협회지
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    • 제61권12호
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    • pp.715-723
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    • 2018
  • Facial soft tissue injury due to trauma is common. Severe damage of soft tissue causes functional and cosmetic problems. In the initial evaluation of patients with facial trauma, airway maintenance and respiratory maintenance are the most important. The principles of treatment include adequate irrigation and debridement, primary closure, or secondary wound healing. Postoperative care such as taping, silicone gel sheeting, and sun screening is important to prevent scarring. The scalp and forehead are abundant in blood and can cause severe bleeding. The eyelid is very thin and has a multi-layered structure, requiring accurate suturing and reconstruction of the layers. It is advisable to determine the presence of hematoma in the ear and treat it. When the cheek area is damaged, it is necessary to identify and treat the damage of the parotid gland and the facial nerve branch. The lips should be sewn with the white roll of lip and vermillion.

Minimizing tissue damage due to filler injection with systemic hyperbaric oxygen therapy

  • Hong, Woo Taik;Kim, JIye;Kim, Sug Won
    • 대한두개안면성형외과학회지
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    • 제20권4호
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    • pp.246-250
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    • 2019
  • Recently, there is a growing interest of hyperbaric oxygen therapy in many fields of medicine. We had a 43-year-old female patient presented with severe necrosis of the nose, philtrum, and upper lip due to retrograde arterial occlusion after nasolabial fold hyaluronic acid filler injection. Our patient went through 43 sessions of systemic hyperbaric oxygen therapy from December 2, 2017 to January 18, 2018. We administered 2.8 atmosphere absolute (ATA) for 135 minutes in the first session and the remaining sessions consisted of 2.0 ATA for 110 minutes. In reporting this case, we wish to provide a warning regarding the latent risk of filler injections and share our experience about minimizing soft tissue damage in the early stages with systemic hyperbaric oxygen therapy.

산부인과 펄스형 $CO_2$ 레이저의 펄스모듈 특성에 의한 동작파형의 일정한 시스템의 구현 (Fixed system of action waveform by pulse module special quality of obstetrics and gynecology pulse style $CO_2$ laser relationship embodiment)

  • 김휘영
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
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    • pp.159-161
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    • 2007
  • $CO_2$ laser sees that is most suitable to get this effect through minimum formation damage and advantage that is root enemy of effect that happen in minimum cellular tissue depth of 0.1mm is stable living body organization or internal organs institution. Formation damage by ten can be related in formation's kind or energy density, length of evaporation time. If shorten evaporation time, surroundings cellular thermal damage 200 - because happen within 400ums laser beam in rain focus sacred ground surroundings cellular tissue without vitiation me by evaporation Poe of very small floor as is clean steam can. Application is possible to vulva cuticle cousins by a paternal aunt quantity, uterine cancer, cuticle tumor by laser system that $CO_2$ laser gets into standard in obstetrics and gynecology application. Because effect that super pulse output is ten enemies of laser if uniformity one pulse durations are short almost is decreased, most of all pulse module special quality of pulse style $CO_2$ laser for obstetrics and gynecology mode stabilization by weight very, in this research to get into short pulse duration and higher frequency density, do switching by high frequency in DC-DC Converter output DC's ripple high frequency to be changed, high frequency done current ripple amount of condenser for output filter greatly reduce can. Ripple of output approximately to Zero realization applying possible inductor realization through a special quality experiment do.

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Protection against Whole Body γ-Irradiation Induced Oxidative Stress and Clastogenic Damage in Mice by Ginger Essential Oil

  • Jeena, Kottarapat;Liju, Vijayasteltar B;Ramanath, Viswanathan;Kuttan, Ramadasan
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.1325-1332
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    • 2016
  • Radioprotective effects of ginger essential oil (GEO) on mortality, body weight alteration, hematological parameters, antioxidant status and chromosomal damage were studied in irradiated mice. Regression analysis of survival data in mice exposed to radiation yielded LD50/30 as 7.12 and 10.14 Gy for control (irradiation alone) and experimental (GEO-treated irradiated) mice, respectively, with a dose reduction factor (DRF) of 1.42. In mice exposed to whole-body gamma-irradiation (6 Gy), GEO pre-treatment at 100 and 500 mg/kg b.wt (orally) significantly ameliorated decreased hematological and immunological parameters. Radiation induced reduction in intestinal tissue antioxidant enzyme levels such as superoxide dismutase, catalase, glutathione peroxidase and glutathione was also reversed following administration of GEO. Tissue architecture of small intestine which was damaged following irradiation was improved upon administration of GEO. Anticlastogenic effects of GEO were studied by micronuclei assay, chromosomal aberration and alkaline gel electrophoresis assay. GEO significantly decreased the formation of micronuclei, increased the P/N ratio, inhibited the formation of chromosomal aberrations and protected agaisnt cellular DNA damage in bone marrow cells as revealed by comet assay. These results are supportive of use of GEO as a potential radioprotective compound.

산부인과 펄스형 $CO_2$ 레이저의 펄스 특성에 의한 안정된 동작파형의 시스템 (System of stable action waveform by pulse special quality of obstetrics and gynecology pulse style $CO_2$ laser)

  • 김휘영
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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    • pp.55-57
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    • 2007
  • $CO_2$ laser sees that is most suitable to get this effect through minimum formation damage and advantage that is root enemy of effect that happen in minimum cellular tissue depth of 0.1mm is stable living body organization or internal organs institution. Formation damage by ten can be related in formation's kind or energy density, length of evaporation time. If shorten evaporation time, surroundings cellular thermal damage 200 - because happen within 400ums laser beam in rain focus sacred ground surroundings cellular, tissue without vitiation me by evaporation Poe of very small floor as is clean steam can. Application is possible to vulva cuticle cousins by a paternal aunt quantity, uterine cancer, cuticle tumor by laser system that $CO_2$ laser gets into standard in obstetrics and gynecology application. Because effect that super pulse output is ten enemies of laser if uniformity one pulse durations are short almost is decreased, most of all pulse module special quality of pulse style $CO_2$ laser for obstetrics and gynecology mode stabilization by weight very, in this research to get into short pulse duration and higher frequency density, do switching by high frequency in DC-DC Converter output DC's ripple high frequency to be changed, high frequency done current ripple amount of condenser for output filter greatly reduce can. Ripple of output approximately to Zero realization applying possible inductor realization through a special quality experiment do.

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Chloroform에 의한 Rat 간(肝) 및 위장(胃臟) 장해(障害)에 미치는 화분립(花粉粒)의 영향(影響) -병리조직학적 소견- (Effect of Pollen Load on Chloroform-induced Hepatic and Renal Damage in Rats -Concerning Pathohibtological Aspects-)

  • 권정숙;윤수홍
    • 한국식품영양과학회지
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    • 제15권3호
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    • pp.229-234
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    • 1986
  • 화분립(花粉粒)의 chloroform으로 인한 간(肝) 및 위장조직(胃臟組織)에 미치는 영향을 알기 위해 rat에 농도별로 chloroform을 투여하고 또 이들과 화분립(花粉粒)을 함께 투여(投與)한 결과, chloroform 농도가 증가할 수록 조직파괴 및 지방변성이 심했으며, 화분립(花粉粒)을 함께 투여(投與)함으로 조직파괴 정도가 약화됨을 알 수 있었고, 화분립(花粉粒)과 함께 투여(投與)하는 chloroform의 농도가 낮을수록 대조군(對照群)의 조직(組織)에 가까운 형태로 회복됨을 볼 수 있었다.

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HIFU: 현황 및 기술적 동향 (High Intensity Focused Ultrasound for Cancer Treatment: Current Agenda and the Latest Technology Trends)

  • 서종범
    • The Journal of the Acoustical Society of Korea
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    • 제29권2E호
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    • pp.55-63
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    • 2010
  • High Intensity Focused Ultrasound (HIFU) is a noninvasive surgical method mainly targeting deeply located cancer tissue. Ultrasound is generated from an extemally located transducer and the beam is focused at the target volume, so that selective damage can be achieved without harm to overlying or surrounding tissues. The mechanism for cell killing can be combination of thermal and cavitational damage. Although cavitation can be an effective means of tissue destruction, the possibility of massive hemorrhage and the unpredictable nature of cavitational events prevent clinical application of cavitation. Hence, thermal damage has been a main focus related to HIFU research. 2D phased array transducer systems allow electronic scanning of focus, multi-foci, and anti-focus with multi-foci, so that HIFU becomes more applicable in clinical use. Currently, lack of noninvasive monitoring means of HIFU is the main factor to limit clinical applications, but development in MRI and Ultrasound Imaging techniques may be able to provide solutions to overcome this problem. With the development of advanced focusing algorithm and monitoring means, complete noninvasive surgery is expected to be implemented in the near future.

X-ray Computed Tomography를 이용한 콘크리트의 손상파라미터 정량화 (Introduction to Qunatification of Damage Parameters for Concrete Using X-ray Computed Tomography)

  • 박대효;박재민;안태송
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2003년도 가을 학술발표회 논문집
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    • pp.501-504
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    • 2003
  • The purpose of this work is to introduce some fundamental stereological concepts to quantify damage parameters using X-ray CT(Computed Tomography) in the scope of CDM(Continuum Damage Mechanics). X-ray CT is a completely nondestructive technique for visualizing features in the interior of opaque solid objects, and for obtaining digital information on their 3D geometries and properties. Many researchers have introduced lots of damage parameters to model the mechanical behavior of deteriorated materials. Those damage parameters can be represented in many forms such as specific void or crack surfaces, the spacing between cracks, the specific damaged surface area, the specific damaged surface area tensor, the mean solid path among the damaged surfaces and the mean solid path tensor. Despite of many accomplishments in CDM since there is no the systematic experiment, it have limitations in application. In this situation, X-ray computed tomography is highlited by many researchers and applied in a wide range of materials including rock, bone, ceramic, metal, soft tissue and concrete.

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Is optimal cutting temperature compound essential embedding solution treatment to cryo-sectioning of brain tissue?

  • Baek, Hye Kyung;Song, Ji Ae;Yi, Sun Shin
    • 대한수의학회지
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    • 제56권2호
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    • pp.85-89
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    • 2016
  • We tested a set of conditions for obtaining optimal tissue quality in preparation for histology in samples of mouse brain. C57BL/6J mice were sacrificed and perfused with 4% paraformaldehyde, after which the brains were removed and dehydrated in 30% sucrose solution. The brains were then divided into four groups according to freezing temperature and usage of optimal cutting temperature (OCT) compound. Next, we stained the sectioned brain tissues with Harris hematoxylin and eosin Y and immunohistochemistry was performed for doublecortin. The best quality tissue was obtained at $-25^{\circ}C$ and by not embedding with the OCT compound. When frozen at $-25^{\circ}C$, the embedded tissue was significantly damaged by crystals, while at $-80^{\circ}C$ there were no meaningful differences between qualities of embedded- and non-embedded tissues. Overall, we identified a set of conditions to obtain quality frozen brain sections. Our developed protocol will help resolve matters associated with damage caused to sectioned brain tissue by crystal formation during freezing.