• Title/Summary/Keyword: Tip-off

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Development of Optical Fiber Glucose and Lactate Biosensors for Bioprocess Monitoring (생물공정 모니터링을 위한 광섬유 포도당 및 젖산 센서의 개발)

  • Jung, Chang Hwan;Sohn, Ok-Jae;Rhee, Jong Il
    • KSBB Journal
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    • v.32 no.1
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    • pp.35-45
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    • 2017
  • In this work the optical fiber glucose and lactate biosensors were developed by using fluorescent dye and enzyme immobilized on the end tip of an optical fiber. 3-Glycidyloxypropyl)methyldiethoxysilane (GPTMS), (3-Aminopropyl) trimethoxysilane (APTMS) and Methyltrimethoxysilane (MTMS) were used to immobilize glucose oxidase (GOD), lactate oxidase (LOD) and ruthenium(II) complex (tris(4,7-diphenyl-1,10-phenanthroline) ruthenium(II), $Ru(dpp)_3^{2+}$) as oxygen sensitive fluorescent dye. MTMS sol-gel was an excellent supporting material for the immobilization of $Ru(dpp)_3^{2+}$, GOD, and LOD on the optical fiber. Storage stability of the optical fiber glucose sensor was kept constant over 20 days, while the optical fiber lactate sensor had constant storage stability over 17 days. The optical fiber glucose and lactate biosensors also maintained good operational stability for 20 hours and 14 hours, respectively. The activities of the immobilized enzymes were most excellent at pH 7 and at $25^{\circ}C$. On-line monitoring of glucose and lactate in a simulated process was performed with the optical fiber glucose and lactate biosensors. On-line monitoring results were agreed with those of off-line data measured with high performance liquid chromatography (HPLC).

A Study on Steady-State Performance Simulation of Smart UAV Propulsion System (신개념 비행체 추진시스템의 정상상태 성능모사 기법 연구)

  • 공창덕;강명철;기자영;양수석;이창호
    • Journal of the Korean Society of Propulsion Engineers
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    • v.7 no.3
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    • pp.38-44
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    • 2003
  • In this study, a performance model of the smart UAV propulsion system with ducts, tip jets and variable main nozzle, which has flight capability of the rotary wing mode for the take-off/landing and low speed forward flight as well as the fixed wing mode for high speed forward flight, has been newly developed With the proposed model, steady-state performance analysis was performed at various flight modes such as rotary wing mode, fixed wing mode, compound ing mode and altitude as well as at flight speed conditions. In investigation of performance analysis. it was noted that the operational capability of the propulsion system was limited due to the duct losses depending on each flight mode, and the limitation with the altitude variation case had much greater than that with the flight speed variation case.

A Study on Steady-state Performance Simulation of Smart UAV Propulsion System (신개념 비행체 추진시스템의 정상상태 성능모사 기법 연구)

  • 공창덕;강명철;기자영;양수석;이창호
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2003.05a
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    • pp.177-182
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    • 2003
  • In this study, a performance model of the Smart UAV propulsion system with ducts, tip jets and variable main nozzle, which has flight capability of the rotary wing mode for the take-off/landing and low speed forward flight as welt as the fixed wing mode for high speed forward flight, has been newly developed. With the proposed model, steady-state performance analysis was performed at various flight modes and conditions, such as rotary wing mode, fixed wing mode, compound wing, mode altitude and flight speed. In investigation of performance analysis, it was noted that the operational capability of the propulsion system was limited due to the duct losses depending on each flight mode, and the limitation with the altitude variation case has much greater than that with the flight speed variation case.

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Phase criterion of the feedback cycle of edgetones (쐐기소리의 되먹임 사이클의 위상조건)

  • Gwon, Yeong-Pil
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.20 no.3
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    • pp.1106-1113
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    • 1996
  • The phase criterion of the feedback cycle of low-speed edgetones has been obtained using the jet-edge interaction model which is based on the substitution of an array of dipoles for the reaction of the wedge to the impinging jet. The edgetone is produced by the feedback loop between the downstream-convected sinuous disturbance and upstream-propagating waves generated by the impingement of the disturbance on the wedge. By estimation of the phase difference between the downstream and the upstream disturbances, the relationship between the edge distance and the wavelength is obtained according to the phase-locking condition at the nozzle lip. With a little variation depending on the characteristics of jet-edge interaction, the criterion can be approximated as follows: h/.LAMBDA. + h/.lambda. = n - 1/4, where h is the stand-off distance between the nozzle lip and the edge tip, .LAMBDA. is the wavelength of downstream-convected wave, .lambda. is the wavelength of the upstream-propagating acoustic wave and n is the stage number for the ladder-like characteristics of frequency. The present criterion has been confirmed by estimating wavelengths from available experimental data and investigating their appropriateness. The above criterion has been found to be effective up to 90.deg. of wedge angle corresponding to the cavitytones.

An Investigation on Milking Disturbances of Mammary System (젖소 필유계(泌乳係)의 착유장애(搾乳障碍)에 관한 조사(調査))

  • Cheong, Chang Kook;Nam, Tchi Chou;Shin, Tong Woo
    • Korean Journal of Veterinary Research
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    • v.21 no.2
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    • pp.151-159
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    • 1981
  • An investigation on various causes of milking disturbances resulting from injuries and abnormalities of mammary system were made in 2,179 Holstein cows. To perform this investigation, 69 dairy farms of the suburban area of Seoul city, Gyeonggi-do and Chungnam provinces were andomly selected and subjected. Diagnosis was made by means of inspection and palpation of teat, insertion of teat canula, checking milk machines, anamneses and farm records. This investigation was, actively done from March 1977 to February 1979, The results obtained were summerized as follows; 1. It was found that 446 cows, accounting for 20.48% of 2,179 cows inspected, had supernumerary teats. Among them 53.59% had one, 43.72% had two, 2.47% had three, and 0.22% had four supernumerary teats, respectively. 2. Dry off quarters were found in 158 quarters which turned out to be 1.8% of 8,716 quarters inspected. Among dry off quarters, 62.02% seemed to be caused by mastitis, 30.37% by acquired teat obstructions, and 7.59% by congenital blind teats and glands respectively. 3. Teat sphincter stenosis was found in 154 teats of 50 cows, which represents 1.76% of 8,716 teats and 2.29% of 2,179 cows inspected, respectively. Among 154 teats with teat sphincter stenosis, 138 teats (85.7%) of 33 cows were found to be congenital and revealed highest incidence. 4. Loose sphincter was found in 78 teats of 36 cows, which figure 0.89% of 8,7l6 teats and 1.69% of 2,179 cows inspected, respectively. Among 78 teats with loose sphincter, 52 teats (66.66%) of 13 cows were found to be congenital and revealed highest incidence. 5. Injured teat tip caused by over milking of milk machine, was found in 229 teats of 156 cows, which figure 2.63% of 8,716 teats and 7.15% of 2,179 cows observed, respectively. 6. Other miscellaneous injuries and congenital abnormalities of teats and udders were diagnosed as follows: The teat laceration was found in 34 teats (0.39% of 8,716 teats), fissure of teat skin in 24 teats (0.28% of 8,716 teats), stricture of teat cistern in 21 teats (0.24% of 8,716 teats), teat fistula in 12 teats (0.14% of 8,716 teats), papillomas on testes in 8 teats (0.09% of 8,716 teats). Knothole orifice in 7 teats (0.08% of 8,716 teats), subcutaneous abscess of udder in 5 quarters (0.05% of 8,716 teats), membraneous obstruction of teat cistern in 4 teats (0.05% of 8,716 teats), and congenital short teat in 8 teats (0.09% of 8,716 teats), respectively.

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Sternal Retraction and Subclavian Vein Catheter Occlusion during Cardiac Surgery

  • Tarbiat, Masoud;Bakhshaei, Mohammad Hossein;Derakhshanfar, Amir;Rezaei, Mahmoud;Ghorbanpoor, Manoochehr;Zolhavarieh, Seyed Mohammad
    • Journal of Chest Surgery
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    • v.54 no.5
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    • pp.377-382
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    • 2021
  • Background: Subclavian vein (SV) catheterization is a method for the delivery of fluids, drugs, and blood products, venous blood sampling, and central vein pressure monitoring in cardiac surgery. Catheter occlusion is a serious complication of SV catheterization during cardiac surgery, especially after sternal retractor expansion. Methods: In this observational study, 303 patients who had successful right infraclavicular SV catheterization from September 2019 to April 2020 were enrolled to determine the incidence of catheter occlusion. After catheterization, the lumens of all catheters were checked for the ability to infuse and withdraw blood from the catheter before and after sternal retractor expansion. The patients' characteristics, cannulation approach, on-pump or off-pump technique, occlusion of the catheter and its lumens, and any associated complications were recorded. The data were analyzed using IBM SPSS ver. 22.0 (IBM Corp., Armonk, NY, USA). Results: Of the 303 patients studied, 205 were male (67.7%) and 98 were female (32.3%). Catheter occlusion occurred in 11 patients with on-pump cardiopulmonary bypass (CPB) (227 patients) and 4 patients with off-pump CPB (76 patients) (p=0.863). The incidence of catheter occlusion was 4.95% (15 of 303 patients) with no cases of simultaneous 3-lumen occlusion in a catheter. The most commonly occluded lumen was the distal lumen (57.92%). Simultaneous 2-lumen occlusion occurred in 4 patients. Catheter occlusion was found in 3 of 13 malpositioned catheters (23.07%). Conclusion: The current study showed that malpositioning of the catheter tip was a risk factor for catheter occlusion and that the distal lumen of a triple-lumen catheter was the most commonly occluded lumen.

Development of high performance and low noise compact centrifugal fan for cooling automotive seats (자동차 시트 쿨링용 고성능·저소음 컴팩트 원심팬 개발)

  • Kim, Jaehyun;Ryu, Seo-Yoon;Cheong, Cheolung;Jang, Donghyeok;An, Mingi
    • The Journal of the Acoustical Society of Korea
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    • v.37 no.6
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    • pp.396-403
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    • 2018
  • In this paper, a high-performance and low-noise centrifugal fan is developed for cooling automotive seats which provide a driver with pleasant driving environment. First, the flow characteristics of the existing fan unit was analyzed using a fan performance tester and CFD (Computational Fluid Dynamics) simulations. The analysis of the predicted flow field indicated vortex flow near the tip of fan hub and stagnation flow on the top of fan hub. Two design points are devised to reduce the vortex flow and the stagnation flow observed in the existing fan unit. First, the cut-off clearance which is the minimum distance between the fan blade and the fan housing is increased to reduce the vortex strength and, as a result, to reduce the overall sound pressure level. Second, the hub shape is more modified to eliminate the stagnation flow. The validity of proposed design is confirmed through the numerical analysis. Finally, a prototype is manufactured with a basis on the numerical analysis result and its improved flow and noise performances are confirmed through the P-Q curves measured by using the Fan Tester and the SPL (Sound Pressure Level) levels measured in the anechoic chamber.

Two Visualization Techniques Using Smoke-wire and Micro Water-droplets and Their Applications to Vortex Flows (연기선과 미세 수적을 이용한 두 가지 가시화 기법과 와류에의 적용)

  • Sohn, Myong Hwan
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.44 no.12
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    • pp.1017-1026
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    • 2016
  • The present paper describes the two off-surface visualization techniques and their application examples to vortex flows. One of the two visualization techniques is the classical smoke-wire technique, and the other is the visualization technique using the micro water-droplets generated by the home-style ultrasonic humidifier. The smoke-wire technique has the limit of air flow speed (about 5 m/sec for 0.07 mm-diameter wire) and the pollution problem, but it produces very fine and clear streak line sheet. It is applied to visualize the wing-tip vortices of a 3-dimensional wing. The micro water-droplet technique has the larger limit of air flow speed (above 10 m/sec) and is free from pollution and toxic problems compared to the smoke-wire technique. It is successfully applied to visualize the complex vortex system of a double-delta wing with an apex strake.

An Experimental Study of the Performance Characteristics on a Multi-Stage Micro Turbine with Various Stages (다단 마이크로터빈에서 단수 변화에 따른 터빈의 성능에 관한 실험적연구)

  • Cho, Chong-Hyun;Cho, Soo-Yong;Choi, Sang-Kyu
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.12
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    • pp.76-82
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    • 2005
  • An experimental study on an axial-type micro turbine which consists of maximum 6 stages is conducted to measure aerodynamic characteristics on each stage. This turbine has a 2.0 flow coefficient, 3.25 loading coefficient and 25.8mm mean diameter. The solidity of stators and rotors is within a 0.67~0.75, and the off-design performance is measured by changing the load after adjusting the mass flowrate and the total pressure to constant at inlet. A maximum specific output power of 2kW/kg/sec is obtained in one stage, but the increment of the specific output power with increasing stages is alleviated. In case of torque, the increment of the torque maintains to constant at low RPM region, but its increment become dull at high RPM region. The efficiency of the micro turbine becomes low because the tip gap effect is great due to the small blade, but it could be improved by increasing the stages.

A Study on the Interface Micromotions of Cementless Artificial Hip Replacement by Three-Dimensional FEM (무시멘트형 인공고관절 대치술후 초기의 경계면 미세운동의 3차원 FEM 연구)

  • Kim, S.K.;Chae, S.W.;Choi, H.Y.
    • Proceedings of the KOSOMBE Conference
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    • v.1994 no.12
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    • pp.71-74
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    • 1994
  • In cementless total hip arthroplasty(THA), an initial stability of the femoral component is mandatory to achieve bony ingrowth and secondary long term fixation. Bone ingrowth depends strongly on relative micromotion and stress distributions at the interface. Primary stability of the femoral component can be obtained by minimizing the magnitude of relative micromotions at bone-prosthesis interface, Hence an accurate evaluation of interface behavior and stress/strain fields in the bone implant system may be relevant for better understanding of clinical situations and improving THA design. However, complete evaluation of load transfer in the bone remains difficult to assess experimentally, Hence, recently finite element method (FEM) was introduced in orthopaedic research field to fill the gap due to its unique capacity to evaluate stress in structure of complex shape, loading and material behavior. The authors developed the 3-dimensional numerical finite element model which is composed of totally 1179 elements off and 8 node blick. We also analyzed the micromotions at the bone-stem interface and mechanical behavior of existing bone prosthesis for a loading condition simulating the single leg stance. The result indicates that the values of relative motion for this well fit Multilock stem were $150{\mu}m$ in maximum, $82{\mu}m$ in minimum, and the largest relative motion developed in medial region of proximal femur with anterior-posterior direction. The proximal region of the bone was much larger in motion than the distal region and the stress pattern shows high stress concentration on the cortex near the tip of the stem. These findings indicates that the loading in the proximal femoral bone in the early postoperative situation can produce micromotions on the interface and clinically cementless TEA patient should not be allowed weight bearing strictly early in the postoperative period.

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