• Food Science of Animal Resources
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• v.25 no.2
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• pp.232-237
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• 2005

Lactoferrin is a member of the transferrin family of iron-binding glycoproteins. It is originally found in milk. In addition to its antibacterial and antiviral activities, lactoferrin has many other biological functions include anti-inflammatory properties, antitumor, cell growth-promoting activity as well as antioxidant effect In the present study, we report the production of recombinant bovine lactoferrin and lactoferrin N-lobe in the Rhodococcus erythropolis (R erythropolis) using pTip vector. The expression level was investigated in various range of temperature, and we could successfully expressed the bovine lactoferrin and lactoferrin N-lobe in R erythropolis at low temperature. The recombinant proteins were purified by Nickel-Nitrolotriacetic acid (Ni-NTA). The purified proteins were confirmed by SDS-PAGE and Western blot, which indicating that the recombinant proteins have a molecular weight of 80kDa and 43kDa for bovine lactoferrin and lactoferrin N-lobe, respectively.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.2
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• pp.100-106
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• 2006

The behavior of spray impinging on the inclined constant temperature flat plate was experimentally investigated. To clarify the wall effect of a high pressure DISI injector, a relative angle of the inclined wall to a spray axis was varied. Spray penetration along the wall was observed optically and it was compared with that of a Fan spray type and Swirl type spray. To evaluate various spray motion quantitatively, a spray path penetration which describe the development of a spray tip along the wall was newly introduced. To observe the structure of an impinging spray, it was visualized by a controlled stroboscope light and its visualized image was captured on an CCD camera. Using the digital image of impinging spray $H_x$ and $R_x$ was extracted to clarify the structure of impinging spray. The main parameter of the relative position of the wall was the inclined angle which was defined as the angle was varied from $0^{\circ}$ (vertical impingement) to $60^{\circ}$ at the same condition.

• Transactions of the Korean Society of Automotive Engineers
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• v.20 no.2
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• pp.116-122
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• 2012

The purpose of this study is to investigate the overall spray behavior characteristics for various injection conditions in a gasoline direct injection(GDI) injector with multi-hole. The spray characteristics, such as the spray penetration, the spray angle, and the injection quantity, were studied through the change of the injection pressure, the ambient pressure, and the energizing duration in a high-pressure chamber with a constant volume. The n-heptane with 99.5% purity was used as the test fuel. In a constant volume chamber, the injected spray was visualized by the spray visualization system, which consisted of the high-speed camera, the metal-halide lamp, the injector control device, and the image analysis system with the image processing program. It was revealed that the injection quantity was mainly affected by the difference between the injection pressure and the ambient pressure. For low injection pressure conditions, the injection quantity was decreased by the increase of the ambient pressure, while it nearly maintained regardless of the ambient pressure at high injection pressure. According to the increase of the ambient pressure in the constant volume chamber, the spray development became slow, consequently, the spray tip penetration decreased, and the spray area increased. In additions, the circular cone area decreased, and the vortex area increased.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.5
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• pp.424-432
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• 2011

Shape parameters and design variables for a centrifugal compressor impeller were investigated for optimizing a centrifugal compressor. In order to compare the performance of an optimized impeller with the performance of the original impeller, an already tested impeller was chosen and design variables for optimization were selected. The meridional shapes at the shroud and at the hub were re-designed using the Bezier curve. The camber-lines of the impeller blade at the hub and at the tip were also expressed by the Bezier curve. The shape curves for impeller could be expressed using 6-8 control points. Among them, eight control points which have strong effect to the shape can be selected as design variables for optimization. Therefore, any impeller which is expressed by data points for its shape can be optimized using few design variables.

• The Korean Journal of Pain
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• v.10 no.2
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• pp.214-219
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• 1997

Background: Epidural neural blockade with local anesthetics combined with steroids has been in clinical trials for patients with low back pain. But pain treatment of low back pain remains somewhat problematic. Many patients with low back pain have epidural fibrosis and adhesions proved with magnetic resonance imaging(MRI) examination. These findings might play an important role in the origin of back pain. Present study was aims to investigate the effect of epidural adhesiolysis in patients with low back pain. Methods: We investigated 76 patients suspected with epidural fibrosis and adhesion was suspected. Nerve pathology was demonstrated and epidural fibrosis suspected or proved with MRI examination. 17G needle specially designed by Racz was inserted at sacral hiatus and catheter was inserted untill its tip was located at lesion site under fluoroscopic guidance. Injection of contrast dye was achieved and prospected spread of agents. Injection of 0.25% bupivacaine, triamcinolone, and 10% hypertonic saline via catheter were carried out daily for 3 days. Evaluation included assessment of pain relief (Numerical Rating Scale; NRS) post-epidural adhesiolysis 3 days, 1 week, and 3 months. We also looked for complication of epidural adhesiolysis. Results: Statistical analysis(Friedman nonparametric repeated measures test and Dune's multiple comparison test) demonstrated NRS was significantly less during 3 months after epidural adhesiolysis(P<0.05). Especially, there is a extremely significance in post-epidural adhesiolysis 3 days (P<0.001). Only four patients reported any complications the most common symptom among three persistent headache but disappeared after a few months without residual sequelae. Conclusion: We conclude epidural adhesiolysis is a safe and effective method of pain therapy for low back pain with proven lumbo-sacral fibrosis and adhesion. A direct visualization by epiduroscopy may be more useful to the resulting functional changes after epidural adhesiolysis.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.54 no.10
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• pp.438-442
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• 2005

Si nanocrystal (Si NC) memory device has several advantages such as better retention, lower operating voltage, reduced punch-through and consequently a smaller cell area, suppressed leakage current. However, the physical and electrical reasons for this behavior are not completely understood but could be related to interface states of Si NCs. In order to find out this effect, we characterized electrical properties of Si NCs embedded in a SiO$_{2}$ layer by scanning probe microscopy (SPM). The Si NCs were generated by the laser ablation method with compressed Si powder and followed by a sharpening oxidation. In this step Si NCs are capped with a thin oxide layer with the thickness of 1$\~$2 nm for isolation and the size control. The size of 51 NCs is in the range of 10$\~$50 m and the density around 10$^{11}$/cm$^{2}$ It also affects the interface states of Si NCs, resulting in the change of electrical properties. Using a conducting tip, the charge was injected directly into each Si NC, and the image contrast change and dC/dV curve shift due to the trapped charges were monitored. The results were compared with C-V characteristics of the conventional MOS capacitor structure.

• Geomechanics and Engineering
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• v.20 no.2
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• pp.87-101
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• 2020

The construction of combined pile-raft foundations is considered as the main option in designing foundations in high-rise buildings, especially in soils close to the ground surface which do not have sufficient bearing capacity to withstand building loads. This paper deals with the geotechnical report of the Northern Fereshteh area of Tabriz, Iran, and compares the characteristics of the single pile foundation with the two foundations of pile group and geogrid. Besides, we investigate the effects of five principal parameters including pile diameter and length, the number of geogrid layers, the depth of groundwater level, and pore water pressure on vertical consolidation settlement and pore water pressure changes over a year. This study assessed the mechanism of the failure of the soil under the foundation using numerical analysis as well. Numerical analysis was performed using the two-dimensional finite element PLAXIS software. The results of fifty-four models indicate that the diameter of the pile tip, either as a pile group or as a single pile, did not have a significant effect on the reduction of the consolidation settlement in the soil in the Northern Fereshteh Street region. The optimum length for the pile in the Northern Fereshteh area is 12 meters, which is economically feasible. In addition, the construction of four-layered ten-meter-long geogrids at intervals of 1 meter beneath the deep foundation had a significant preventive impact on the consolidation settlement in clayey soils.

• Clean Technology
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• v.17 no.4
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• pp.300-305
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• 2011

A mixture of supercritical carbon dioxide and a co-solvent was employed to strip a high-dose ion-implanted photoresist (HDIPR) from the surface of semiconductor wafers. The stripping efficiency was highly improved by the physical force generated from a ultrasonication tip inside the reactor. In addition, helium gas was injected in the reactor as a barrier gas before the introduction of pure supercritical $CO_2$ ($scCO_2$), which reduced the rinsing time significantly. The effect of co-solvents on the stripping efficiency was investigated. The wafer surfaces were analyzed by scanning electron microscopy and by an energy dispersive X-ray spectrometer.

• Journal of the Korean Society for Precision Engineering
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• v.31 no.6
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• pp.551-557
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• 2014

Ideally, it is preferable to obtain the fracture characteristics of a piping from the fracture toughness of real pipes. However, a fracture toughness test on real pipes not only incurs much expense, but is very difficult to perform. Therefore fracture toughness tests have been carried out with standard specimens instead of real pipes. But, the estimates of fracture toughness obtained from standard specimens are more conservative than those of real pipes owing to the difference in the constraint effect between real pipes and standard specimens. Therefore, we have been studied with equivalent stress gradient specimen (ESG) which is designed to behave equally compared to real pipe about stress gradient on crack tip. In this study, we will evaluate fracture characteristics of equivalent stress gradient specimen by using analytical methods and compare with those of real pipe. And finally investigate suitability of equivalent stress gradient specimen.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.15 no.4
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• pp.703-713
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• 2002

Recently, an improved EFG(Element-Free Galerkin) crack analysis technique, which includes a discontinuous approximation and a singular basis function on the auxiliary supports, was developed. The technique is able to accurately analyze the crack propagation problem without any modification of the analysis model; however, it shows some dependency on the analysis parameters used. In this study, the effect of analysis parameters such as the size of compact support, dilation parameter, the smoothness of shape function around the crack tip, and the number of node using auxiliary supports on the accuracy of solution has been investigated. Through a patch test with a crack, relative L₂ error norm of stresses and the stress intensity factor were computed and compared for various analysis parameters and the results were presented as guidelines for adequate choice of analysis parameters.