• 생명과학회지
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• 제15권3호
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• pp.427-433
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• 2005

초파리는 유전학, 발달 생물학, 행동 유전학, 노화 연구에 이르기까지 수많은 연구에 이용 되어져 왔다. 최근 초파리 전체 유전자의 염기서열이 보고되었으며, 유전자의 기능 분석과 발현 단백질에 대한 연구가 진행되고 있다. 본 연구에서는 야생형 초파리에서 추출한 단백질을 이차원 전기영동을 통해 400여개 이상의 단백질 스폿으로 분리하였으며, 각 스폿을 적출하여 트립신으로 처리하여 얻어진 펩타이드 단편을 MALDI-TOF-MS를 이용한 펩타이드 지문 검색으로 질량을 측정하였다. 측정된 질량을 초파리 데이터 베이스를 이용하여 분리한 단백질을 동정함으로써 59개의 유전자에서 발현되는 65개의 단백질 스폿을 동정하였다. 이러한 결과는 향후의 발생단계, 외부 자극, 노화 등에 관련되는 특이적 단백질 연구의 기초 자료로 활용될 수 있을 것이다.

• 대한토목학회논문집
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• 제44권2호
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• pp.215-221
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• 2024

정부는 신재생에너지 정책을 통해 신재생에너지 시설확대를 독려하고 있다. 그러나 신재생에너지 발전시설 설치로 인해 발생하는 경관훼손, 전자파발생, 부동산 가치하락, 환경오염 등의 사유로 인해 지역주민들의 민원이 발생한다. 이는 발전사업자와 주민들 사이에서 갈등을 만들며, 사업 진행을 어렵게 만든다. 본 연구는 비협조적 게임이론을 적용하여, 주민참여를 통해 발전사업자와 주민들의 갈등을 해결한 신재생에너지 발전 사업 8가지 사례를 분석하고자 한다. 인근 이해당사자인 지역주민들의 투자를 받아, 주민들은 최대 25 %에서 최소 4.1 %의 수익률을 얻었다. 주민들은 발전사업 추진에 동의하고, 발전사업자는 수익의 일부를 주민들과 공유하는 것이 게임이론 분석을 통해 모두에게 우월전략임을 확인했다. 우월 전략이 만나는 지점은 내쉬균형을 형성하며, 동시에 파레토최적점이 되어 발전사업자와 주민 모두에게 이익이 된다는 분석결과를 도출하였다.

• 한국미생물·생명공학회지
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• 제43권3호
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• pp.177-186
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• 2015

국내 식품공전에 기술되어 시행중인 식품 내 벤조피렌 분석법은 회수율, 검출 및 정량 한계, 효용성과 정확성 등이 검증되어 적용되고 있다. 그러나, 기존의 시험법에는 시료의 추출 및 분리, 정제 등의 복잡한 전처리 과정이 포함되어 있다. 환경 및 식품 내 위해물질 검출법의 연구 및 개발의 현 추세는 시험비용과 시간소모를 최소화하고 시험과정을 단순화할 수 있는 비표지, 비파괴 분석법을 통해 관리 현장에서의 신속대응을 지향하고 있다. 본 총설에서는 현행의 벤조피렌 분석법에 대해 정리하고, 그 한계점을 극복하기 위한 새로운 시도로 라만 분광법을 이용한 벤조피렌 검출법에 대해 소개하고자 한다.

• Asian review of World Histories
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• 제4권1호
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• pp.3-34
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• 2016

This introduction is both a statement of a research problem and an account of the first research results for its solution. As more historical databases come online and overlap in coverage, we need to discuss the two main issues that prevent 'big' results from emerging so far. Firstly, historical data are seen by computer science people as unstructured, that is, historical records cannot be easily decomposed into unambiguous fields, like in population (birth and death records) and taxation data. Secondly, machine-learning tools developed for structured data cannot be applied as they are for historical research. We propose a complex network, narrative-driven approach to mining historical databases. In such a time-integrated network obtained by overlaying records from historical databases, the nodes are actors, while thelinks are actions. In the case study that we present (the world as seen from Venice, 1205-1533), the actors are governments, while the actions are limited to war, trade, and treaty to keep the case study tractable. We then identify key periods, key events, and hence key actors, key locations through a time-resolved examination of the actions. This tool allows historians to deal with historical data issues (e.g., source provenance identification, event validation, trade-conflict-diplomacy relationships, etc.). On a higher level, this automatic extraction of key narratives from a historical database allows historians to formulate hypotheses on the courses of history, and also allow them to test these hypotheses in other actions or in additional data sets. Our vision is that this narrative-driven analysis of historical data can lead to the development of multiple scale agent-based models, which can be simulated on a computer to generate ensembles of counterfactual histories that would deepen our understanding of how our actual history developed the way it did. The generation of such narratives, automatically and in a scalable way, will revolutionize the practice of history as a discipline, because historical knowledge, that is the treasure of human experiences (i.e. the heritage of the world), will become what might be inherited by machine learning algorithms and used in smart cities to highlight and explain present ties and illustrate potential future scenarios and visionarios.

• 동의신경정신과학회지
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• 제12권2호
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• pp.135-146
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• 2001

Insomnia is one of the most common symtoms of Neuropsychiatry patients. These are many approaches to treat insomnia, but it is difficult to be resolved completely. Acupuncture and Auricular acupuncture have been used for relief insomnia. But it is not sufficient to compare the effect of Acupuncture treatment and Auricular acupuncture treatment. Thus we investigate the effect of Acupuncture treatment group and Auricular acupuncture treatment group. A clinical analysis was carried out for 40 patients who was treated insomnia with Acupuncture(20 patients) and Auricular acupuncture(20 patients) in Seoul Dong-Seo Oriental Hospital. 1. Total duration of sleeping time showed $1.55{\pm}1.1574$ hours increased in Acupuncture group and $0.925{\pm}1.184$ hours increased in Aricular acupuncture group. especially Acupuncture were much more effective method than Aricular acupuncture. P-value was 0.033 (P <0.05) 2. Delaying time before the onset of sleep showed $0.7375{\pm}0.8940$ hours decreased in Acupuncture group and $0.7969{\pm}1.3298$ hours decreased in Auricular acupuncture group. (P <0.05) 3. The wake times showed $0.9167{\pm}1.7299$ times decreased in Acupuncture group and $1.2308{\pm}1.1658$ times decreased in Auricular acupuncture group in sleep maintenance insomnia. (P <0.05) 4. Change in quality of sleep showed Excellent 30%, Good 50%, Fair 15%, Poor 5% in Acupuncture group and Excellent 20%, Good 45%, Fair 30%, Poor 5% in Aruricular acupuncture group.

• 한국컴퓨터정보학회논문지
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• 제19권12호
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• pp.187-196
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• 2014

본 논문에서는 고정된 역간 거리를 정해진 운전 시분내에 주행에너지를 최소화하며 주행하는 열차의 특성을 파악하고 수학적으로 모델링한다. 도시철도차량 자동주행에 일반적으로 사용되는 PID제어기 대신 목표값에 추종하면서도 자동 주행 중 소비에너지가 최소화되도록 최적제어기를 사용하여 철도 차량를 모델링하였으며 실제 동일한 운행조건하에서 설계한다. 실제 선로 조건을 적용하여 별도의 차상장치나 선로주변시설 없이도 자동운전 중 주행에너지를 최소하여 주행에너지를 절감하고자 한다. 따라서 8호선 실 노선 구간별 운전시분 내에서 실측 데이터 분석을 위해 직선구간/구배구간/곡선구간 등 구간을 선정하고 그 구간에서 열차의 운행패턴에 따라 에너지를 절감하는 열차운행을 방법을 제시하였다.

• Clinics in Shoulder and Elbow
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• 제1권2호
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• pp.167-174
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• 1998

Since the first description by Cotton, there have been sporadic reports about the inferior subluxation of the shoulder. Nevertheless there is still a lack of consensus regarding the mechanism of occurrence, evolution and treatment. We have experienced six cases of inferior sublusation(five cases after trauma and one case after surgery) which resolved over time. Analysis of the clinical informations including serial radiographs, data from clinical examination and electromyography(EMG) revealed the following results. All the five post-traumatic inferior subluxations were noted in women with an average age of 59 years after direct trauma resulting in fracture of the proxiaml hrnerus(4) or clavicle(1), of which nerve injury was proven by EMG in three. One case occurred after Bankart repair by stretch injury to the axillary nerve. The presenting symptom was unusually severe pain on passive motion. Absence of anterior or posterior displacement wasl confirmed by radiographs. All the cases seemed to have delayed onset of subluxation except one. The subluxed hu.meral head was concentrically reduced at an average 11 weeks(range 3-23 weeks) from the supposed time of occurrence and the acromiohumeral interval measUred on the standing anteroposterior radiographs decreased to 9.4 mm ftom 23 mm. Improvement of pain paralled the reduction. In conclusion, the most common cause of transient inferior subluxation was nerve injury in ou~ series and the prognosis was excellent, however protraction of recovery or leaving permanent subluxation would be possible if .the injured nerve is unrecoverable.

• Journal of Electrical Engineering and Technology
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• 제13권2호
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• pp.902-910
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• 2018

In recent times, development of nanofluid insulation for power transformers is a hot research topic. Many researchers reported the enhancement in dielectric characteristics of nano modified mineral oils. Considering the drawbacks of petroleum based mineral oil, it is necessary to understand the dielectric characteristics of nanofluids developed with natural ester based oils. Palm oil has better insulation characteristics comparable to mineral oil. However very few research reports is available in the area of nanofluids based on palm oil. Partial discharge (PD) is one of the major sources of insulation performance degradation of transformer oil. It is essential to understand the partial discharge(PD) characteristics by collecting huge data base of PD performance of nano modified palm oil which will increase its confidence level for power transformer application. Knowing these facts, in the present work, certain laboratory experiments have been performed on PD characteristics of nano $SiO_2$ modified palm oil at different electrode configurations. Influence of concentration of nano filler material on the PD characteristics is also studied. Partial discharge inception voltage, Phase resolved partial discharge (PRPD) pattern, PD signal time-frequency domain characteristics, PD signal equivalent timelength-bandwidth mapping, Weibull distribution statistical parameters of PRPD pattern, skewness, repetition rate and phase angle variations are evaluated at different test conditions. From the results of the experiments conducted, we came to understand that PD performance of palm oil is considerably enhanced with the addition of $nano-SiO_2$ filler at 0.01%wt and 0.05%wt concentration. Significant reduction in PD inception voltage, repetition rate, Weibull shape parameter and PD magnitude are noticed with addition of $SiO_2$ nanofillers in palm oil. These results will be useful for recommending nano modified palm oil for power transformer applications.

• Corrosion Science and Technology
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• 제2권2호
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• pp.88-92
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• 2003

The technique for in situ simultaneous measurements of IR-RAS and QCM, which has been developed for investigation of corrosion in gaseous environments, was employed to study the effects of an extremely thin water layer on the corrosion rate. An evaporated copper film on a QCM element was exposed to air containing water vapor and $SO_2$, and time-resolved IR-RAS spectra were measured and mass gains were simultaneously followed with QCM. The tested ranges of relative humidity (RH) and concentration of $SO_2$ were 60% - 90% and 1 - 20 ppm, respectively. On the basis of 2D-IR analysis, the corrosion products were determined to be Chevreul's salt ($CuSO_3Cu_2SO_3{\cdot}2H_2O$) and $CuSO_4{\cdot}5H_2O$. By constructing curves of the relations between band intensities of IR spectra and mass gains of QCM for the corrosion products, the time variations in each product were determined from spectral experiments on copper plates. The thicknesses of physically adsorbed water layers in course of the corrosion process were also determined from water band intensities. The results showed that the thickness of the physically adsorbed water layer increased with increase in RH, and it also increased with increase in accumulation of corrosion products. The latter is probably due to the capillary effect of the corrosion products.

• Korean Circulation Journal
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• 제52권8호
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• pp.606-620
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• 2022

Background and Objectives: Protein-losing enteropathy (PLE) is a devastating complication after the Fontan operation. This study aimed to investigate the clinical characteristics, treatment response, and outcomes of Fontan-associated PLE. Methods: We reviewed the medical records of 38 patients with Fontan-associated PLE from 1992 to 2018 in 2 institutions in Korea. Results: PLE occurred in 4.6% of the total 832 patients after the Fontan operation. After a mean period of 7.7 years after Fontan operation, PLE was diagnosed at a mean age of 11.6 years. The mean follow-up period was 8.9 years. The survival rates were 81.6% at 5 years and 76.5% at 10 years. In the multivariate analysis, New York Heart Association Functional classification III or IV (p=0.002), low aortic oxygen saturation (<90%) (p=0.003), and ventricular dysfunction (p=0.032) at the time of PLE diagnosis were found as predictors of mortality. PLE was resolved in 10 of the 38 patients after treatment. Among medical managements, an initial heparin response was associated with survival (p=0.043). Heparin treatment resulted in resolution in 4 patients. We found no evidence on pulmonary vasodilator therapy alone. PLE was also resolved after surgical Fontan fenestration (2/6), aortopulmonary collateral ligation (1/1), and transplantation (1/1). Conclusions: The survival rate of patients with Fontan-associated PLE has improved with the advancement of conservative care. Although there is no definitive method, some treatments led to the resolution of PLE in one-fourth of the patients. Further investigations are needed to develop the best prevention and therapeutic strategies for PLE.