• Computers and Concrete
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• v.19 no.1
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• pp.51-58
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• 2017

The paper presents the experimental investigations for studying the effect of ground granulated blast furnace slag (GGBFS) on the time-dependent deflection of reinforced concrete (RC) beams due to creep and shrinkage. The RC beams were reinforced with 2-10 mm bars at tension side and subjected to constant sustained two-point loading for the period of 150 days. The amount of cement replacement by GGBFS was varied from 0 to 60% with an increment of 20%. The total deflection was measured at different ages of up to 150 days under sustained loads. The experiments revealed that the time-dependent deflection of the reinforced concrete RC beams containing GGBFS was higher than that of plain concrete RC beams. At 150 days, the average creep and shrinkage deflection of RC beams containing 20%, 40% and 60% GGBFS was 1.25, 1.45 and 1.75 times higher than the plain concrete beams. A new model, which is an extension of authors' earlier model, is proposed to incorporate the effect of GGBFS content in predicting the long-term deflection of RC beams. Besides validating the new model with the current data with higher percentage of tension reinforcement, it was also used to predict the authors' earlier data containing lesser percentage of tension reinforcement with reasonable accuracy.

• Journal of the Korean Society of Safety
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• v.24 no.6
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• pp.103-110
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• 2009

Since the mechanical properties of cement-based materials are time-dependent due to the prolonged cement hydration process, those of fiber reinforced concrete(FRC) may also be time-dependent. Toughness is one of important properties of FRC. Therefore, it should be investigated toughness development of FRCs with curing ages to fully understand the time-dependent characteristics of FRCs. To this end, the effect of curing ages on flexural toughness development of steel fiber reinforced concrete is studied. Three point bending test with notched beam specimen was adapted for this study. Hooked-end steel fiber(DRAMIX 40/30) was used as a fiber ingredient to investigate w/c ratio and fiber volume fraction effect on toughness development during curing. Three different water-cement ratios(0.44, 0.5 and 0.6) and fiber volume fractions(0%, 0.5% and 1%) were used as influence factors. Each mixture specimens were tested at five different ages, 0.5, 1, 3, 7 and 28 days. The study shows that flexure toughness development with age is quite different than other concrete material properties such as compressive strength. The study also shows that the toughness development trend correlates more closely to water/cement ratio than to fiber volume fraction.

• Korean Journal of Child Studies
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• v.31 no.6
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• pp.1-13
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• 2010

This study examined the time-dependent effects of changes in private education on the trajectories of academic achievement among early adolescents. Five-wave data was employed from the KYPS; the participants being 2844 (1524 boys, 1320 girls). All were 4th graders in 2004 and became 8th graders in 2008. Latent growth curve model indicated that academic achievement significantly decreased over the five time points, but there were significant individual differences as well. Participants who reported higher initial levels of academic achievement tended to decrease in academic achievement more slowly over time compared to participants who reported lower levels of initial academic achievement. The effects of private education on academic achievement were at their most powerful when participants were in the 4th grade. Private educational experiences among 6th graders had relatively less influence upon the academic achievement of 7th graders.

• Geomechanics and Engineering
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• v.33 no.5
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• pp.519-528
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• 2023

In this paper, we present the results of an experimental study on the effect of polymer support fluid on shaft resistance of offshore bored piles. A series of pullout tests were performed on bored piles installed under various boundary conditions considering different types of grounds and support fluids, and a range of support fluid exposure times. Contrary to previous studies concerning onshore bored piles, a time dependent effect of polymer fluid on shaft resistance was observed in all ground types. The adverse effect of polymer support fluid on the shaft resistance, however, was considerably less than bentonite support fluid for a given exposure time. No significant reduction in shaft resistance was evident when limiting the exposure time of the polymer support fluid to the side wall of the borehole within 2-3 hours. The degree to which the polymer fluid affects shaft resistance seemed to vary with the ground type. A proper consideration should be given to the time dependent effect of polymer fluid on shaft resistance of bored piles installed in offshore construction environment to limit its adverse effect on the pile performance. The practical implications of the findings are discussed.

• Steel and Composite Structures
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• v.17 no.4
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• pp.405-429
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• 2014

In this paper, it is aimed to determine the structural behavior of suspension bridges considering construction stages and different soil conditions. Bosporus Suspension Bridge connecting the Europe and Asia in Istanbul is selected as an example. Finite element model of the bridge is constituted using SAP2000 program considering existing drawings. Geometric nonlinearities are taken into consideration in the analysis using P-Delta large displacement criterion. The time dependent material strength of steel and concrete and geometric variations is included in the analysis. Time dependent material properties are considered as compressive strength, aging, shrinkage and creep for concrete, and relaxation for steel. To emphases the soil condition effect on the structural behavior of suspension bridges, each of hard, medium and soft soils are considered in the analysis. The structural behavior of the bridge at different construction stages and different soil conditions has been examined. Two different finite element analyses with and without construction stages are carried out and results are compared with each other. At the end of the analyses, variation of the displacement and internal forces such as bending moment, axial forces and shear forces for bridge deck and towers are given in detail. Also, displacement and stresses for bridge foundation are given with detail. It can be seen from the analyses that there are some differences between both analyses (with and without construction stages) and the results obtained from the construction stages are bigger. It can be stated that the analysis without construction stages cannot give the reliable solutions. In addition, soil condition have effect on the structural behavior of the bridge. So, it is thought that construction stage analysis using time dependent material properties, geometric nonlinearity and soil conditions effects should be considered in order to obtain more realistic structural behavior of suspension bridges.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.5
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• pp.597-605
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• 2018

In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent $K^+$ (Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits. The Kv current amplitude was progressively inhibited by propafenone in a dose-dependent manner, with an apparent $IC_{50}$ value of $5.04{\pm}1.05{\mu}M$ and a Hill coefficient of $0.78{\pm}0.06$. The application of propafenone had no significant effect on the steady-state activation and inactivation curves, indicating that propafenone did not affect the voltage-sensitivity of Kv channels. The application of train pulses at frequencies of 1 or 2 Hz progressively increased the propafenone-induced inhibition of the Kv current. Furthermore, the inactivation recovery time constant was increased after the application of propafenone, suggesting that the inhibitory action of propafenone on Kv current is partially use-dependent. Pretreatment with Kv1.5, Kv2.1 or Kv7 inhibitor did not change the inhibitory effect of propafenone on the Kv current. Together, these results suggest that propafenone inhibits the vascular Kv channels in a dose- and use-dependent manner, regardless of $Na^+$ channel inhibition.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.745-755
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• 2002

To examine the effects of Yunpyesan on the cell proliferation of A549 human lung carcinoma cell line, we performed various experiments such as dose-dependent effect of Yunpyesan on cell proliferation and viability, morphological changes, quantification of apoptotic cell death and alterations of apoptosis/cell cycle-regulatory gene products. Yunpyesan declined cell viability and proliferation in both a dose- and a time-dependent manner. The anti-proliferative effect by Yunpyesan treatment in A459 cells was associated with morphological changes such as membrane shrinking and cell rounding up. Yunpyesan Induced apoptotic cell death in a time-dependent manner, which was associated with degradation of poly-(ADP-ribose) polymerase (PARP), an apoptotic target protein, without alterations of the balance between Bcl-2 and Bax expressions. DNA flow cytometric histograms showed that population of G1 phase of the cell cycle was increased by Yunpyesan treatment in a dose-dependent manner. Western blot analysis revealed that cyclin D1 and A were reduced by Yunpyesan treatment, whereas cyclin dependent kinase (Cdk) inhibitor p27 was markedly increased in a time-dependent fashion. The level of tumor suppressor p53 proteins was also increased by Yunpyesan treatment and its increase might be linked to increase of Cdk inhibitor p27. In addition, Mdm2, negative regulator of p53, was down-regulated by Yunpyesan treatment. Since the expression of retinoblastome protein (pRB), a key regulator of G1/S progression, was reduced by Yunpyesan treatment, we supposed that phosphorylation of pRB might be also blocked. The present results indicated that Yunpyesan-induced inhibition of lung cancer cell proliferation is associated with the induction of apoptosis and the blockage of G1/S progression.

• Proceedings of the Korean Geotechical Society Conference
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• 2004.03b
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• pp.407-414
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• 2004

Interfacial properties between rock mass and shotcrete play a significant role in the transmission of loads from the ground to shotcrete. These properties have a major effect on the behaviours of rock mass and shotcrete. They, however, have merely been assumed in most of numerical analyses, and little care has been taken in identifying them. This paper aimed to identify interfacial properties including cohesion, tension, friction angle, shear stiffness, and normal stiffness, through direct shear tests as well as interface normal compression tests for shotcrete/rock cores obtained from a tunnel sidewall. Mechanical properties such as compression strength and elastic modulus were also measured to compare them with the time-dependent variation of interfacial properties. Based on experiments, interfacial properties between rock and shotcrete showed a significant time-dependent variation similar to those of its mechanical properties. In addition, the time-dependent behaviours of interfacial properties can be well regressed through exponential and logarithmic functions of time.

• Transactions of the Korean Society of Mechanical Engineers
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• v.10 no.4
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• pp.456-462
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• 1986

본 논문은 Voigt형의 고체점성을 갖는 단순기지보에 외부기진력이 sin(1/2 at$^{2}$+1/3bt$^{3}$)인 꼴로 작용할 때에 축하중 및 각속도의 변화에 따른 동적 처짐 효과를 고찰하였다.

• Journal of The Korean Astronomical Society
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• v.27 no.2
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• pp.177-190
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• 1994

We have examined the photometric evolution of elliptical galaxies, using stellar evolutionary models covering the wide ranges of metallicity and mass, and the different IMFs (simple IMP & time-dependent bimodal IMF). The model with a time-dependent bimodal IMF can reproduce the observed integrated magnitudes and colors at all wavelengths. The computed model shows that the star formation in elliptical galaxies is still going on, although the number of newly born stars is very small. The chemical evolutionary effect is clearly seen in the C-M diagram of computed elliptical galaxies.