• Title/Summary/Keyword: Time trend analysis

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Survival Benefit of Perioperative Chemotherapy in Patients with Locally Advanced Gastric Cancer: a Propensity Score Matched Analysis

  • Eom, Bang Wool;Kim, Sohee;Kim, Ja Yeon;Yoon, Hong Man;Kim, Mi-Jung;Nam, Byung-Ho;Kim, Young-Woo;Park, Young-Iee;Park, Sook Ryun;Ryu, Keun Won
    • Journal of Gastric Cancer
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    • v.18 no.1
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    • pp.69-81
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    • 2018
  • Purpose: It has been reported that the survival of patients with locally advanced gastric cancer (LAGC) is better in East Asia countries than in developed western countries; however, the prognosis of LAGC remains poor. This study aimed to evaluate the effects of perioperative chemotherapy on the long-term survival of East Asia patients with LAGC. Materials and Methods: From October 2006 through August 2008, 43 patients with LAGC received perioperative S-1 combined with weekly docetaxel in a phase II study (neoadjuvant group). These patients were matched using propensity scores to patients who underwent surgery without neoadjuvant chemotherapy during the same period (surgery group). The surgical outcomes and long-term survivals were compared between the 2 groups. Results: After matching, 43 and 86 patients were included in the neoadjuvant and surgery groups, respectively, and there was no significant difference in their baseline characteristics. Although the operating time was longer in the neoadjuvant group, there was no significant difference in postoperative complications between the 2 groups. The neoadjuvant group had a significantly higher 5-year overall survival (OS) rate (73.3% vs. 51.1%, P=0.005) and a trend towards higher 5-year progression-free survival (PFS) (62.8% vs. 49.9%, P=0.145). In the multivariate analysis, perioperative chemotherapy was an independent factor for OS, with a hazard ratio of 0.4 (P=0.005) and a marginal effect on the PFS (P=0.054). Conclusions: Perioperative chemotherapy was associated with better long-term survival without increasing postoperative complications in the setting of D2 surgery for patients with LAGC, suggesting that perioperative chemotherapy can be a therapeutic option in East Asia countries.

Experimental Investigation on Torsional Analysis and Fracture of Tripod Shaft for High-speed Train (고속열차용 트리포드 축의 비틀림 해석 및 파단에 대한 실험적 연구)

  • Lee, Joo Hong;Kim, Do Sik;Nam, Tae Yeon;Lee, Tae Young;Cho, Hae Yong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.11
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    • pp.979-986
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    • 2016
  • The tripod shafts of constant-velocity joint are used in both the trains KTX and KTX-sanchon. It is an important component that connects the motor reduction unit and the axle reduction unit in a power bogie. The tripod shaft not only transmits drive and brake torque in the rotational direction, but also slides in the axial direction. If the drive system is loaded with an excessive torque, the fuse part of the shaft will be fractured firstly to protect the other important components. In this study, a rig was developed for conducting torsion tests on the tripod shaft, which is a type of mechanical fuse. The tripod shafts were subjected to torsional fracture test and torsional fatigue test on the rig. The weak zone of the tripod shaft was identified, and its fatigue life was predicted using finite element analysis (FEA). After analyzing the FEA results, design solutions were proposed to improve the strength and fatigue life of the tripod shaft. Furthermore, the deterioration trend and time for failure of the tripod shaft were verified using the hysteresis loops which had been changed with the advancement of the torsional fatigue test.

A Study on Narrative in Louise Bourgeois' "You Better Grow Up" (루이즈 부르주아의 작품 의 내러티브 분석)

  • Oh, Sang-Il
    • Journal of Science of Art and Design
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    • v.9
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    • pp.49-87
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    • 2006
  • Narrative has broad domains. So it is related to the everything man faces in his daily life and also performed in various modes. Narrative is revealed through all media including a character, which is also applied to plastic art. And narrative objects formed beyond the differences in media aid forms of expression are commonly based on a language. The study on such objects which created a new conceit of narratology can be said to be a spiritual trend by which to understand the world and man from the viewpoint of a 'story'. Plastic art took high interest in narrative in the same period as the rise of postmodernist art in the latter half of the 20th century, which was also applied to sculpture. The researcher, therefore, investigated through the history of sculpture in the 20th century the process in which narrative was denied under the value system of modernism and reappeared with the quickening of postmodernism. And as a result this period could be briefly characterized by 'return to figure' and 'reappearance of narrative'. The is, such flow means that late sculpture converted its center of interest from simple geometric abstract forms to irregular, figurative images. The researcher chose as the subject of his study the work of Louise Bourgeois, who was judged to have performed narrative positively and successfully among a great number of performed narrative positively and successfully among a great number of postmodernist sculptors who adopted it as their own strategy of expression. As the central artist of postmodrnist sculpture, She expressed human desire and condition as sexuality through the introspection of her own personal experience in contrast to the character of pop art sensitive to external world. The researcher borrowed narrative semiotics as a method of analyzing more elaborately the problem about the generation of narrative shown in her works. For it, he selected as the sample work for analysis Bourgeois's , which were judged to contain narrative most abundantly and as the metaphor of a gaze and recollection presented a new woman self that sublimed love, hatred, and loneliness. The narrative in her works are characterized by introspection questioning one's own trauma. It has independent domain and characteristics and clearly reveals narrative and content-centered characteristics, which are commonly discovered in postmodernist sculpture. The researcher could more concretely and definitely understand the characteristics of narrative through figurative images by analyzing the sample work. The researcher wanted to call your attention to the fact that the sculpture in the late 20th century contained narrative commonly and uniformly despite being characterized by various expressions and modes. And the focused on highlighting the fact that the narrative was more effectively revealed through figurative images of human body and simultaneously analyzing the formalizing process and structure for narrative. Besides he wanted to argue that the position of narrative defining the characteristics of sculpture should be valued more justly. Also, such acceptance of narrative, which is discovered in the sculpture, will have to be understood as the characteristics of the period reflecting the cultural aspect of the present time.

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Development of Reference Material Using Natural Seawater for Nutrient Analysis in Seawater (자연해수를 이용한 해수 중 영양염 분석용 표준물질 개발)

  • Rho, Taekeun;Kang, Dong-Jin;Kim, Eun-Soo;Kahng, Sung-Hyun;Cho, Sung Rok;Lee, Jung Moo;Park, Eun Ju;Moon, Cho-Rong
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.20 no.1
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    • pp.29-35
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    • 2015
  • Dissolved nutrients in seawater are recognized as an essential biogeochemical factor for detecting global environmental changes. The importance of nutrient reference material for seawater has been increased greatly for the comparison of nutrient data, measured in different time and space in global ocean by various researchers with different levels in nutrient analysis skill. In this study, we described the homogeneity and stability of nutrient reference material for seawater using natural seawater, collected at a station of Shihwa Lake, at a coastal station near Uljin (surface water), and at a station over the Ulleung Basin (surface water and 1500 m depth water) and sterilized. Based on the homogeneity data, the nutrient reference materials has similar homogeneity compared to other nutrient reference materials. During 3-13 month period, there was no unidirectional trend of increase or decrease in nutrient concentration of newly developed nutrient reference material for seawater. However, a sustained measurement is required to check stability for longer period.

The Evolution of IT architecture in Universities: A Case study of Korean Domestic Universities (대학 정보기술 아키텍처 발전방향에 관한 연구: 국내 대학 사례를 중심으로)

  • Yoon, Sung-Chul;Suh, Hyun-Suk;Lee, Seog-Jun
    • Information Systems Review
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    • v.4 no.2
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    • pp.111-131
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    • 2002
  • Strategic information systems assist organization with the significant opportunity to gain competitive advantage in executing its business plans and realizing its business goals. The universities establish long-range plan of information systems in an effort to provide just-in-time, useful, efficient and effective information services to their members such as professors, students, and staffs when carrying out various organizational activities. The university information systems started from the primitive computer-based application, extended to the administrative and educational e-transformation, even to the virtual university concept. Through an empirical analysis and complementary case examples, the current study carefully chose three Korean universities according to their chronological importance, that have undergone the information systems planning process years from 1995 to 2001. These universities then, were compared in terms of the information technology architecture: the information architecture, infra architecture, and information management architecture. These three areas of system were cross-examined under the consideration of the evolution of information technology architecture, and its impact on the development of university e-transformation. As part of a fulfillment plan to satisfy the needs of customers of current trend, it is evident that the university e-transformation provides a stepladder to highly competitive, first class university in the market, through achieving the educational advancement, research enhancement, and administrative efficiency. The result of the study analysis indicates that, of the three architectures examined, the weakness showed in the information management architecture. Therefore it is crucial for the university staffs, managers and professors to understand the significance of the successful implementation of the information system and its maintenance. Our study certainly will act as a catalyst for the promotion of the future university e-transformation projects.

Methodological Research on the Instruments of Fatty Acids Determination (지방산의 기기 측정 방법에 관한 연구)

  • 박선미;안명수
    • Korean journal of food and cookery science
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    • v.7 no.1
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    • pp.45-51
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    • 1991
  • In this study, several standard fatty acids were analyzed by three analysis instruments. And also, for the two kinds of soybean oils, fatty acids compositions were determined by three instruments. The results were obtained as follows: 1. In the case of Gas Chromatography (GC), standard fatty acids (Myristic, Stearic, Linoleic, Linolenic, Arachidonic acid) were determined with high reproducibility, but oleic acid/elaidic acid were not seperated. By Capillary Gas Chromatography (CGC), most of standard fatty acids were determined with very high reproducibility than saturated fatty acids, and palmitic acid/oleic acid were not seperated. 2. In the analytical ability of cis-trans fatty acids isomer (oleic acid/elaidic acid), CGC was shown better analytical ability of geometrical isomer than HPLC. Oleic acid/elaidic acid were not seperated by packed column (15% DEGS). The rquire time for standard fatty acids analysis was as follows; GC, 7.21 min., CGC, 9.84 min., HPLC, 24.48 min. 3. The major compositions of fatty acids of each soybean oil (CSOY; refined, DSOY; unrefined) by GC and CGC were linoleic acid, oleic acid, palmitic acid, linolenic acid and stearic acid. But in the case of HPLC, palmitic acid/oleic acid were not seperated. Analytical ability of three instruments on fatty acids composition in each soybean oil was same trend as in the standard fatty acids mixture.

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Prediction of Urban Land Cover Change Using Multilayer Perceptron and Markov Chain Analysis (다층 퍼셉트론(MLP)과 마코프 체인 분석(MCA)을 이용한 도심지 피복 변화 예측)

  • Bhang, Kon Joon;Sarker, Tanni;Lee, Jin-Duk
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.36 no.2
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    • pp.85-94
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    • 2018
  • The change of land covers in 2026 was prediceted based on the change of urbanization in 1996, 2006 and 2016 in Seoul and surrounding areas in this study. Landsat images were used as the basic data, and MLP (Multilayer Perceptron) and MCA (Markov Chain Analysis) were integrated for future prediction for the study area. The land cover transition potentials were calculated by setting up sub-models in MLP and the driving factors of land cover transition from 1996 to 2006 and transition probabilities were calculated using MCA to generate the land cover map of 2016. This was compared to the land cover map of 2016 from Landsat. MLP and MCA were verified and the future land covers of 2026 were predicted using the land cover map from Landsat in 2006 and 2016. As a result, it was predicted that the major land cover changes from 1996 to 2006 were from Barren Land and Grass Land to Builtup Area, and the same trend of transition will be remained for 2026. This study is meaningful in that it is applied for the first time to predict the future coating change in Seoul and surrounding areas by the MLP-MCA method.

A Study on Developing Trend of Core-Banking Model through Tracking of Financial IT Development (금융IT 발전과정의 추적을 통한 코어뱅킹 모델의 발전방향에 관한 연구)

  • Weon, Dal-Soo;Jun, Moon-Seog
    • The KIPS Transactions:PartD
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    • v.19D no.1
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    • pp.95-104
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    • 2012
  • The main purpose of this paper is to propose the direction of financial IT development in macro-perspective. And it also shows a theoretical basis on the financial IT system that will be progressed with regard to an empirical model on the basis of the transformation process of the domestic financial IT environment for the future. In the process, this research produces and analyzes the meaningful patterns that have a significant influence on the financial IT development for 40 years, and attempts to backtrack the life-cycle of the core-banking model. This paper can be summarized as follows: Firstly, I analyzed the life-cycle of financial IT system in Korea per 10years. Secondly. The life-cycle of core-banking model is analyzed by 11years on the average and the one of the long term model by 33years. Thirdly, from the earlier days, the models of a long-term survival core-banking have been designed and developed through the objective analysis and bench-marketing. Lastly, the financial IT field should be developed into the integrated industry, and systematization of core-banking model studies and more professionals need to be extended. This research has contributed to provide the new frameworks through the analysis of the core-banking model that has not studied obviously for a long time. The paper involves two related sections, the first section deals with the significance of backtracking in core-banking model and also focuses on the key components from the perspective of financial IT management strategies. Based on the process, the second section figures out the life-cycles of actual core-banking model.

A Study on Main Features of SNS Affecting SNS User Acceptance Decision (SNS의 수용결정에 영향을 미치는 SNS의 주요 특성에 관한 연구)

  • Oh, Eun-Hae
    • Management & Information Systems Review
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    • v.31 no.3
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    • pp.47-73
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    • 2012
  • SNS allowed users to serve not only as the content and message producer but as the consumer, with development into various types of SNS platforms. Instead of a traditional media structure of media-to-many and unspecified users, it also made it possible to achieve one-to-one or one-to-many interactions, regardless of time and space, through SNS platforms. Moreover, according to development of digital communication technology, IT, media contents and communication network have been mutually connected, though they were once separate. The changes in communication environments have caused rapid disorganization and reorganization in popular culture led by specific expert groups. Such trend has a greater influence on marketing strategies of enterprises. In other words, it will lead them to mostly introduce new information technologies, based on consumer market, and to strategically participate in SNS for promotion and marketing for their products and brands. Likewise, SNS has currently appeared as the main media affecting consumers' behaviors. In consideration of the importance of SNS features, which can stimulate responses of other users, analysis of main features affecting SNS user acceptance decision is required, as well as its utilization strategies. Accordingly, this study conducted division of SNS features into openness, quickness, interactiveness and economical efficiency to derive strategies for increasing the usage frequency of SNS and ultimately maximizing the expectation effect, in addition to an empirical analysis of effects of SNS features on usefulness, easiness and pleasure perceived in SNS, and SNS user intention.

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The First Crustal Refraction Survey in the Korean Peninsula

  • Jung Mo Lee;Wooil Moon;Chang-Eob Baag;Heeok Jung;Ki Young Kim;Bong Gon Jo;Woohan Kim;Sung Kyun Kim
    • Proceedings of the International Union of Geodesy And Geophysics Korea Journal of Geophysical Research Conference
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    • 2003.05a
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    • pp.15-15
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    • 2003
  • The first crustal refraction survey in the Korean Peninsula was carried out over the survey line connecting Seosan-Yeongdong-Kyeongiu on Dec. 15, 2002. The total length of the survey line was about 300 Km and 198 portable seismometers were deployed with approximately 1.5-km interval. The survey line itself was geologically important since it was almost normal to the so-called Sino-Korean structural trend. Two shots, one at Seosan (west end point) and the other at Yeongdong (mid-point), were exploded. They were 100-m deep drill well explosions. The Seosan shot consisted of a ton emulsion type explosive, while Youngdong consisted of 500 kg one. Both shots generated signals with good S/N ratios to the farthest receivers. Seismic signals were recorded by 195 receivers out of 198 ones. Although the originally planned Kyeongju shot (east end point) could not be exploded due to public discontent, the experiment was evaluated very successful. First breaks in all recorded traces were picked up and two preliminary analyses were carried out. The one is conventional flat layer analysis and the other was refraction tomographic analysis. The one resulted in average 32-km thick two-layer crust and the underlying mantle with 8.05-km/s P-velocity. The top crust layer with 3.86 kw/s P-velocity was 2.5-km thick and the lower crust layer with 6.0l km/s P-velocity was 29.5-km thick. The other resulted in a velocity cross-section. The confidence level of the velocity cross-section could not be evaluated at this time because only two shot were exploded. Detailed analyses such as surface wave dispersion are on going. Continuing crustal scale refraction surveys are planned in Korea.

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