• Journal of Korean Neurosurgical Society
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• 제29권9호
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• pp.1161-1170
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• 2000

Objective : The transverse hippocampal slice is one of the most commonly studied in vitro models of mammalian brain physiology. However, despite its broad usage, there has been no standardization of slice preparation techniques or recording condition. It is well known that variations in recording conditions can result in profound different effects to neuronal responses. Evoked field potentials, recorded extracellularly, were used to investigate the effects of variations in hippocampal slice preparation protocol on hypoxia responses of CA1 neurones. Material & Methods : Before hypoxic injury, hippocampal slices were incubated for 4 hours. During incubation period, the slices were placed in a incubation chamber($21^{\circ}C$) for recovery from preparation injury and then transferred to recording chamber($34^{\circ}C$) for more recovery and baseline electric recording with current stimulation(0.1Hz). Various time periods in incubation chamber and recording chamber were applied to each experimental group(group 1=60min : 180min, group 2=90min : 150min, group 3=180min : 60min, time in incubation chamber : time in recording chamber) before 10 min hypoxia produced by replacing 95% $O_2$+5% $CO_2$ mixed gas to 95% $N_2$+5% $CO_2$ gas. Calcium, Magnesium ions and several drugs effecting on glutamate receptor also were studied. Recoveries from hypoxic injury of hippocampal slices were estimated by percent recovery of population spike(PS). Statistic analysis of study were performed using paired t-test. Results : The percent recovery of PS after 10min hypoxia was considerably enhanced by increasing the period of current stimulation during incubation period before hypoxic injury. Temperature effect on the result of this experiment was also studied(group 4) but the result from this showed no statistic significance. Low magnesium ion concentration of artificial CSF(Mg-free aCSF) during incubation period enhanced the recovery of PS but low calcium (calcium-free) and high magnesium ion concentration(2mM) reduced it after hypoxic injury. L-glutamate($100{\mu}M$) and AP-5($50{\mu}M$) had no effect on the recovery of PS but CNQX($10{\mu}M$) in artificial CSF during incubation period markedly enhanced the recovery of PS. Co-treatment of AP-5($50{\mu}M$), CNQX($10{\mu}M$) and high magnesium concentration(2mM) enhanced recovery of PS in immediate following period of hypoxic injury but the effect of cotreatment after then decayed rapidly and lost statistic significance. Conclusions : Judging from above results, the condition of baseline recording is important in observing the recovery of population spike after hypoxia, and the time and the condition should be controled more strictly to obtain reliable results.

• 한국CDE학회논문집
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• 제7권3호
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• pp.148-156
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• 2002

Most Rapid Prototyping (RP) processes adopt a solid Computer Aided Design (CAD) model, which will be sliced into thin layers of constant thickness in the building direction. Each cross-sectional layer is successively deposited and, simultaneously, bonded onto the previous layer; and eventually the stacked layers from a physical part of the model. A new RP process, the transfer-type Variable Lamination Manufacturing process using expandable polystyrene foam sheet (VLM-ST), has been developed to reduce building time and to improve the surface finish of parts with the thick layers and a sloping surface. This paper describes the generation of Unit Shape Layer (USL), the cutting path data of the linen. hotwire cutter for the VLM-ST process. USL is a three-dimensional layer with a thickness of more than 1 mm and a side slope, and it is the basic unit of cutting and building in the VLM-ST process. USL includes data such as layer thickness, positional coordinates, side angles of each layer, hotwire cutting speed, the heat input to the hotwire, and reference shape. The procedure of generating USL is as follows: (1)Generation of the mid-slice from the CAD model, (2)Conversion of the mid-slice into a simply connected domain, (3)Generation to the reference shape for the mid-slice, (4)Calculation of the rotation angle of the hotwire of the cutting system.

• 한국컴퓨터산업학회논문지
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• 제8권2호
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• pp.103-106
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• 2007

동영상 데이터베이스 시스템을 구축하려면 동영상의 샷 경계 검출이 먼저 이루어져야 한다. 그러나 이 과정이 자동화되지 않아 많은 시간과 노력이 필요하다. 샷 경계 검출 알고리즘은 많이 연구되고 있으나 영상 편집시 사용된 편집 효과의 발전에 의하여 완벽한 검출은 매우 어려운 실정이다. 따라서 정확한 샷 경계를 얻기 위해서는 수작업에 의한 검증과 수정이 꼭 필요하다. 시공간 슬라이스는 영상의 내용 변화를 요약한 한 장의 이미지이다. 편집 효과는 수직선, 사선, 곡선, 점진적 색상의 변화 등 시각적으로 인지 가능한 형태로 시공간 슬라이스에 표현된다. 따라서 영상을 재생시키지 않고도 시공간 슬라이스의 변화만으로 샷 경계를 쉽고 빠르게 찾아낼 수 있다. 이 논문에서 제안하고 구현한 시스템은 시공간 슬라이스 상에서 오검출 키 프레임을 삭제할 수 있으며 미검출 된 키 프레임을 생성할 수 있도록 하였다.

• 한국방사선학회논문지
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• 제13권5호
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• pp.705-711
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• 2019

현재 최신 장비의 두부 CT검사에서 파라메타의 변화와 선량변화에 대한 연구가 부족하고 특히 노이즈, 균일도 해석 및 선량변화에 대한 연구가 부족하다고 생각된다. 따라서 높은 사양 두부 CT 사용 시 노출 파라메타 중 관전압, 슬라이스 두께, 피치변화에 대해 분석하여 이때 발생하는 현상에 대해서 연구하고자 하였다. 실험을 통해서 균일도는 고관전압과 두꺼운 슬라이스 선택 및 최저 피치를 사용할 때 균일도가 좋음을 알 수 있었다. 모두 조합한 결과 균일도가 가장 조건은 140 kVp, 10 mm, pitch 0.5로 나타났다. 노이즈는 관전압과 슬라이스 두께를 높이면 피치에 관계없이 개선되는 것을 알 수 있었고, 선량은 관전압과 피치의 증가에 따라 선형적으로 증가하는 것으로 나타났다. 따라서 본 연구결과는 고 사양의 두부 CT 사용에서 참고자료가 될 것이다.

• Journal of Biosystems Engineering
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• 제37권1호
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• pp.36-43
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• 2012

Purpose: Drying characteristics of the sliced carrot and green pumpkin were investigated by using the waste heat dryer. Methods: The effects of drying temperature ($T$) and slice thickness affecting drying time were analyzed. Mathematical models for the drying curves were determined with statistical analysis of drying data. Effective diffusivity was determined for the slices of carrot and green pumpkin under various drying conditions. Results: Drying time was reduced at the drying conditions of thinner slice and higher drying temperature. Moisture ratio ($MR$) according to drying time ($t$) was well presented as an exponential function at all of drying conditions for the slices of carrot and green pumpkin with the determination coefficient ($r^2$) of >0.99. The values of effective diffusivity ($D_{ff}$) of the slices for carrot and green pumpkin were increased with increasing the drying temperature. The relationship between Ln($D_{ff}$) and $1/T$ was linear with the determination coefficient ($r^2$) of >0.97. Conclusions: Drying model was well established as an exponential function at all of drying conditions for drying samples.

• 대한수학회논문집
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• 제33권1호
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• pp.305-315
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• 2018

This note provides a study of lightlike hypersurfaces of a generalized Robertson-Walker(GRW) space-time with a certain screen distribution, which are integrable and have good properties. Focus is to investigate geometric features from the relation of the second fundamental forms between lightlike hypersurfaces and leaves of the integrable screen distribution. Also, we shall apply those results on lightlike hypersurfaces of a GRW space-time to lightlike hypersurfaces of a Robertson-Walker(RW) space-time.

• Journal of Acupuncture Research
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• 제21권4호
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• pp.31-51
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• 2004

Objective: The propose of this study is to investigate the characteristics of combustion in indirect moxibustion with garlic. Methods: We observed the characteristics of combustion by the variations of the thickness(3mm, 4mm, 5mm) of a slice for indirect moxibustion with garlic and mass(80mg, 100mg, 120mg) of moxa cone and existence of holes. The temperature of indirect moxibustion for garlic insulation with holes was higher than temperature of indirect moxibustion for garlic insulation without holes. Combustions time in the preheating period is about 1 minute, it varies by the existence of holes, the thickness of a slice for indirect moxibustion with garlic, and the density of moxa cone. Results: Maximum temperature of heating period was $38.7{\sim}46.2^{\circ}C$, combustion time in the heating period was 118~164sec and maximum ascending temperature gradient was $0.102{\sim}0.264^{\circ}C/sec$. Retaining period was shorter than heating period and stimulus of heating retains more, because it is higher than body temperature. By this report, indirect moxibustion with garlic is more effective with holes and the appropriate thickness of a slice for indirect moxibustion with garlic is 3.5~4mm. It is appropriate that the diameter of moxa cone is 8mm and height of that is 10mm. With this condition, effective combustion period is 120sec, maximum temperature is $42{\sim}44^{\circ}C$, maximum ascending temperature gradient is $0.14{\sim}0.16^{\circ}C/sec$. It is necessary to study clinical correlations for more accurate quantitative standard.

• 대한화학회지
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• 제38권3호
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• pp.200-207
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• 1994

Wistar계 쥐의 신장 조직을 암모니아 기체 감응전극에 고정화하여 조직센서를 제작하고, L-glutamine을 정량하기 위한 최적 조건을 조사하였다. 그 결과, $30^{\circ}C$, pH 7.8의 0.05M 인산완충용액과 30 ${\mu}m$ 두께의 신장을 사용하였을 경우, 정량 가능한 직선범위는$ 8.0{\times}10^{-5}{\sim}1.0{\times}10^{-2} M$이었으며, 감응도는 53.8 mV/decade로 나타났고, 감응시간은 3~5분 소요되었다. 또한 같은 최적 조건하에서 조직을 파쇄하여 얻은 세포소기관을 전극에 고정화시킨 센서의 경우, 정량 가능한 직선범위는 $1.2{\times}10^{-4}{\sim}5.0{\times}10^{-3} M$이었으며, 감응도는 54.0 mV/decade, 감응시간은 6~7분이 소요되었다. 이와 같이 본 연구에서는 쥐의 신장 조직 및 세포 소기관을 이용하여 L-glutamine을 정량 분석할 수 있는 조직센서 개발에 관하여 연구하였다.

• Journal of Communications and Networks
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• 제11권1호
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• pp.1-10
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• 2009

In this paper, we propose a chip-level detection and a spectral-slice scheme for the tunable-transmitter/fixed-receiver (TTFR)-based asynchronous spectral phase-encoded optical codedivision multiple-access (CDMA) system combined with timeencoding. The chip-level detection can enhance the tolerance of multiple access interference (MAI) because the channel collision does not occur as long as there is at least one weighted position without MAI. Moreover, the spectral-slice scheme can reduce the interference probability because the MAI with the different frequency has no adverse effects on the channel collision rate. As a result, these techniques mitigate channel collisions. We analyze the channel collision rate theoretically, and show that the proposed system can achieve a lower channel collision rate in comparison to both conventional systems with and without the time-encoding method.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.21-21
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• 2003

목적： 악성뇌종양 주변부위의 역동자기공명영상에서의 시간신호강도곡선 양상으로 종양의 성장 양상이나 예후를 판단할 수 있는지를 알고자 한다. 대상 및 방법： Anaplastic oligodendroglioma 3예, Anaplastic astrocytoma 1예, Glioblastoma multiforme 1예, Malignant ependymoma 2예, Medulloblastorna 1예로서, 총 8예의 종양절제전, 혹은 후의 잔류 종양을 대상으로 하였다. Routine MRI에 추가하여 종양부위에서 Turbo spin echo T1 강조 역동자기공명영상을 하였으며, Gd-DTPA 0.1 mmol/kg를 급속 주사 한 후, TR/TE, 350/15, slice thickness 6 mm, slice number 3, NEX 2회, scan time은 15 초로 하여 5 분 동안 20회 영상을 얻었다. 가시적으로 조영증강이 없는 종양의 주변부위나 수술경계부위에 관심영역을 그려서 시간신호강도곡선을 얻었으며, 첫 회 조영제 통과시의 peak 이후에 신호가 감소하는 경우를 Normal pattern으로, peak 이후에 신호가 계속 유지되거나 증가하는 경우를 Tumor pattern으로 하였으며, Normal pattern과 Tumor pattern을 보인 예들을 구분하여 종양의 재성장 상태와 환자의 생존 기간을 비교 관찰하였다.