• Journal of Food Hygiene and Safety
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• v.17 no.1
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• pp.20-25
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• 2002

This study was aimed to determine the urinary metabolite of profenofos, one of the organophos-phorus pesticides, as the biomarkers of exposure. Urine samples were collected fort 24 hours in metabolic cages after oral administration and dermal application of profenofos to rats. Identification of the derivatized urinary metabolite was determined by GC/MS and excretion time courses of the urinary metabolite was analyzed by GC/MS. Urinary metabolite of profenofos, 4-bromo-2-chlorophenol, was detected in rats urine both after oral administration and dermal application of profenofos. Parent compound was not detected in the experiment. In GC/MS, the mass spectral confirmation for 4-bromo-2-chlorophenol ion was identified at m/z 208.4-bromo-2-chlorophenol was excreted within 48 hours and 72 hours after oral administration and dermal application of profenofos, respectively. In this study, the same urinary metabolite of profenofos was detected both in oral and dermal exposure. Generally, excretion of the urinary metabolite after oral administration was detected faster than after dermal application. It is suggested that urinary 4-bromo-2-chlorophenol could be used as the biomarkers of exposure to profenofos.

• Journal of Food Hygiene and Safety
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• v.26 no.2
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• pp.91-99
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• 2011

Risk ranking must be determined for various hazards/food combinations to conduct microbial risk management effectively. Risk Ranger is a simple, easy-to-use calculation tool developed in Microsoft Excel and designed to rank the risk (low, medium, and high) for semi-quantitative microbial risk assessment. The user is required to answer 11 questions in Risk Ranger related to 1) severity of the hazard, 2) likelihood of a disease-causing dose of the hazard being present in the meal, and 3) the probability of exposure to the hazard in a defined time. This study determined the risk ranking for twenty three combinations of foodborne pathogens/potentially hazardous foods (PHFs) using a Risk Ranger. In this study, pathogenic E. coli in fresh cut produce salad was scored as 79, which was the highest rank among the 23 combinations of the foodborne pathogens and PHFs. On the other hand, zero risk was obtained with V parahaemolyticus in sushi, Salmonella in meat products and E. coli O157:H7 in hamburger patties. Although Risk Ranger is very simple method to rate the risk of foodborne pathogens and PHFs combination, the accuracy of result was mainly affected by the availability and accuracy of data in the literature. According to the result of literature review, the data are needed for contamination rate of raw materials, consumption amount/frequency of PHFs, and the effect of processing on pathogen. Risk ranking must be continuously revalidated with new data.

• Food Science of Animal Resources
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• v.35 no.1
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• pp.35-40
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• 2015

Super- and sub-critical water treatments have been of interest as novel methods for protein hydrolysis. In the present study, we studied the effect of sub-critical water (Sub-$H_2O$, $300^{\circ}C$, 80 bar) treatment as well as super-critical water (Super-$H_2O$, $400^{\circ}C$, 280 bar) treatment on the physicochemical properties of porcine skin (PS), which has abundant collagen. Porcine skin was subjected to pre-thermal treatment by immersion in water at $70^{\circ}C$, and then treated with sub- or super-critical water. Physicochemical properties of the hydrolysates, such as molecular weight distribution, free amino acid content, amino acid profile, pH, color, and water content were determined. For the molecular weight distribution analysis, 1 kDa hydrolyzed porcine skin (H-PS) was produced by Super-$H_2O$ or Sub-$H_2O$ treatment. The free amino acid content was 57.18 mM and 30.13 mM after Sub-$H_2O$ and Super-$H_2O$ treatment, respectively. Determination of amino acid profile revealed that the content of Glu (22.5%) and Pro (30%) was higher after Super-$H_2O$ treatment than after Sub-$H_2O$ treatment, whereas the content of Gly (28%) and Ala (13.1%) was higher after Sub-$H_2O$ treatment. Super-$H_2O$ or Sub-$H_2O$ treatment affected the pH of PS, which changed from 7.29 (Raw) to 9.22 (after Sub-$H_2O$ treatment) and 9.49 (after Super-$H_2O$ treatment). Taken together, these results showed that Sub-$H_2O$ treatment was slightly more effective for hydrolysis than Super-$H_2O$ was. However, both Sub-$H_2O$ and Super-$H_2O$ treatments were effective processing methods for hydrolysis of PS collagen in a short time and can be regarded as a green chemistry technology.

• Journal of the Korea Concrete Institute
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• v.15 no.2
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• pp.254-262
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• 2003

In this study, the results of applying cold weather concreting mixed with Accelerator for Freeze Protection(AFP) to full scale structures are presented. Since the determination of W/C and amount of AFP significantly have an effect on strength gain and protection of frost damage in early, a full investigation is needed to determine these values at stage of nux design. The flowability of fresh cold weather concreting with AFP was similar to the same W/C. Lower loss of workability and initial slump flow of concrete using superplasticizer of polycarboxylic ester than that of melamine sulphonate showed that polycarboxylic ester was more effective on elapsed time. Temperature histories of specimens located in insulation boxes at the site was similar to that of structures. Thus, it is cleared that simple adiabatic curing method is effective for evaluating in-place concrete strength than specimens cured by sealing method. The investigation results of development of compressive strength of cold weather concreting included AFP with curing methods by logistic curves indicated that AFP can be effective to gain strength at lower temperature than normal curing temperature. In field testing, vinyl sheets were placed over the concrete sections and AFP enabled concrete to gain $5N/{mm}^2$ to protect frost damage in early ages and specified compressive strength of concrete at 28 days under average temperature of $-2^{\circ}C$ (lowest temperature was $-12^{\circ}C$) during site application.

• Journal of Arbitration Studies
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• v.15 no.3
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• pp.55-84
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• 2005

The arbitral award is the decision of the arbitrators on the dispute that had been submitted to them by the parties, either under the arbitration clause providing for the determination of future disputes or under submission of an existing controversy. The arbitral award has the same effect between the parties as a final and binding court judgment. The arbitration award shall acquire, as soon as it is given and delivered to each parties, the authority of res judicata in respect of the dispute it settles. The validity of an award is a condition precent for its recognition or enforcement. The validity of an award depends on the provisions of the arbitration agreement including any arbitration rules incorporated in it, and the law which is applicable to the arbitration proceedings. Such provisions usually address both the form and the content of the award. As the 'form', requires article 32 of Arbitration Act of Korea that an arbitral award should, at least, (1) be made in writing and be signed by all arbitrators. (2) state the reasons upon which it is based unless the parties have agreed that it should not, (3) state its date and place of arbitration. There are some further requirement which may have to be observed before an award which has been made by a tribunal can be enforced. (4) The duly authenticated award signed by the arbitrators shall be delivered to each of the parties and the original award shall be sent to and deposited with the competent court, accompanied by a document verifying such delivery. This rule can be interpreted as if the deposit of an arbitral award with the competent court is always required as a condition for its validity or as a preliminary to its enforcement in Korea. However, we must regard this rule which requires the deposit of an arbitral award with court, as rule of order, but not as condition of its validity. Because that the date on which the award is delivered to each party is important as it will generally determine the commencement of time limits for the making of any appeal which may be available. Furthermore, the party applying for recognition or enforcement merely has to supply the appropriate court with the duly authenticated original award or a duly certified copy thereof, not any document which proves that an the arbitral award is sent to and deposited with the competent court. In order to avoid some confusion which can be caused by its interpretation and application, the Article 32 (4) of Arbitration Act of Korea needs to be abolished or at least modified.

• Journal of IKEEE
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• v.22 no.3
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• pp.638-644
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• 2018

In this paper, we develop a measurement system that uses 3D Scintillator and NaI(TI) Detector to 3-dimensionally identify the location of multiple radiation sources in moving vehicle loads. The radiation measurement system consists of radiation measurement (plastic scintillator), 2-channel Pulse Counter Board, nuclide analysis (NaI(TI) detector) and 1 channel MCA Board. The source locator algorithm calculates the coordinate value of the ratio of the CPS value($1/r^2$) of the source according to the angle(${\theta}$) in inverse proportion to the square of the distance(X, Y) through the SVM classification. The coordinate values are input every predetermined period of the spectrum, and after analyzing the spectrum per unit cycle, the position of the nuclide at the time is calculated by determining whether or not the nuclide is present in the remaining part except for the background area. As a result of the position discrimination test, the error within the international standard of ${\pm}1m$ was shown. Thus, the utility of the proposed system has been demonstrated.

• The Journal of Advanced Prosthodontics
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• v.3 no.3
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• pp.145-151
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• 2011

PURPOSE. This study was performed to investigate the ability of recombinant human-bone morphogenic protein-2 immobilized on a heparin-grafted bone substrate to enhance the osteoblastic functions. MATERIALS AND METHODS. The Bio-$Oss^{(R)}$, not coated with any material, was used as a control group. In rhBMP-2-Bio-$Oss^{(R)}$ group, rhBMP-2 was coated with Bio-$Oss^{(R)}$ using only deep and dry methods (50 ng/mL, 24 h). In heparinized rhBMP-2-Bio-$Oss^{(R)}$ group, dopamine was anchored to the surface of Bio-$Oss^{(R)}$, and coated with heparin. rhBMP-2 was immobilized onto the heparinized- Bio-$Oss^{(R)}$ surface. The release kinetics of the rhBMP-2-Bio-$Oss^{(R)}$ and heparinized rhBMP-2-Bio-$Oss^{(R)}$ were analyzed using an enzyme-linked immunosorbent assay. The biological activities of the MG63 cells on the three groups were investigated via cytotoxicity assay, cell proliferation assay, alkaline phosphatase (ALP) measurement, and calcium deposition determination. Statistical comparisons were carried out by one-way ANOVA test. Differences were considered statistically significant at $^*$P<.05 and $^{**}$P<.001. RESULTS. The heparinized rhBMP-2-Bio-$Oss^{(R)}$ showed more sustained release compared to the rhBMP-2-Bio-$Oss^{(R)}$ over an extended time. In the measurement of the ALP activity, the heparinized group showed a significantly higher ALP activity when compared with the non-heparinized groups (P<.05). The MG63 cells cultivated in the group with rhBMP-2 showed increased calcium deposition, and the MG63 cells from the heparinized group increased more than those that were cultivated in the non-heparinized groups. CONCLUSION. Heparin increased the rhBMP-2 release amount and made sustained release possible, and heparinized Bio-$Oss^{(R)}$ with rhBMP-2 successfully improved the osteoblastic functions.

• Journal of Korea Game Society
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• v.9 no.6
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• pp.105-116
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• 2009

The motives of human beings provide reasons to set goals and carry them out. Accordingly, to realize the behaviors of agents similar to human beings, research using motives has been actively conducted. However, it is difficult for this research to cope with unexpected situations in a dynamic environment as does the research in a static environment. Agents can set goals by themselves in the dynamic environment. Furthermore, the goals that are finally selected shall be quickly and definitely set. This study suggests how to determine motives using them in order to enable agents to set goals by themselves. The suggested method compares motives generated by recognizing the environment by phase in real time and identifies the appropriateness of this method. The identified motives are used to set up the goals of agents and to practice the goals. For the appropriateness of the suggested method, the experiment to compare the behaviors of agents with different features in a virtual environment was conducted. The results of the experiment indicate that when several motives are generated, the agents found the most appropriate motive in the present situation. Accordingly, the agents were able to set up optimum goals so that they could cope with dynamic environments using the final motives identified by the determination of motives.

• Journal of the Korean GEO-environmental Society
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• v.10 no.7
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• pp.7-14
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• 2009

The correlation equation empirically proposed to obtain compression indexes has been proposed to conveniently obtain the value using the soil parameter that can be obtained through simple tests when the number of time of consolidation testing is low or the distribution is large but most of the analyzed regions are limited to certain regions abroad or in the country and multiple data were integrated for use in many cases, thus it is not very reasonable to apply it. Therefore, to establish a new design method considering the uncertainty of the ground, it was selected the Kwangyang port area of which the data have been collected recently thus are relatively more reliable as the subject region of the study in order to maximally reduce the uncertainty of test data. After performing the verification of the normality of the consolidation test data obtained from the selected region and the transformation of variables, a prediction formula was proposed through the regression model with the transformed variables and the proposed regression model with transformed variables was compared with existing empirical equations to verify the suitability of the proposed model formula. After analyzing, it was confirmed that the coefficient of determination was increased after the Box-Cox variable transformation, thus the explanatory power was being enhanced and through the root-mean-square-error method, it was confirmed that the proposed model formula showed the most closed value to the test value.

• Journal of Korean Tunnelling and Underground Space Association
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• v.14 no.6
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• pp.575-593
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• 2012

This paper briefly introduces the scope and objectives of SKB Task 8, which is an international cooperative research project. In addition, the hydraulic behaviors of bentonite buffer focusing on the interactions between bentonite and a rock mass with a joint were investigated using TOUGH2 code as part of a sub-mission of Task 8a. The effects of a rock joint and high capillary pressure of bentonite on the re-saturation properties and pressure distribution in a buffer were identified and successfully incorporated in the TOUGH2 code. Based on the numerical results, it was found that the speed of re-saturation in bentonite surrounded by a rock mass with a joint is 2.5 to 12 times faster than that in a condition without a rock joint, while the degree of saturation in the lower part of the buffer material is generally higher than in the upper part in both the cases of with and without a joint. It can be anticipated that the results obtained from this study can be applied to an estimation of the full saturation time and a determination of optimum thickness with regard to the design of the bentonite buffer in a high level waste disposal system.