• Journal of Korean Society of Archives and Records Management
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• v.15 no.3
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• pp.55-86
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• 2015

This paper aims to interrogate the layered and dependent structure of the modern and official document management in Korea and Japan from 1894 to 1910. The focus of its study is on documents related with the strategic infrastructure construction in Jeonbuk Province through an analysis from the perspective of historic archival studies. For this study, the chosen period was when Japanese imperialists were on their way to seize the Korean official archival system. As such, our objects are the documents connected with the institution of the Japanese resident-general system in Korea and its infrastructural constructions as part of Japan's war plans of invading the continent. Among others, we examined the documents of the strategic infrastructure construction around Jeonju in Jeonbuk Province by Imperial Japan, in order to wage the Sino-Japanese War and subdue the Donghak Peasant Revolution. More specifically, we illuminate the sources and organization of the approval of the original documents in a higher level that is relevant to the determination of political, financial, and personnel matters, which were designed for the Japanese governmental rule over Korea from the era of the Gabo Reform to the period of the Japanese resident-generals, as well as analyze the actual states of the official documents ina lower level, which were drawn up by Korean government and the resident-general. Consequently, this paper suggests that official Korean archival system at this time must be understood under the context of a layered and dependent structure within the vertical connections between Korea and Japan, and not from the point of view of a national history.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.1
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• pp.65-73
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• 2016

Korea Food and Drug Administration (KFDA) has officially announced 2,4-dinitrophenylhydrazine (DNPH) derivatization - high performance liquid chromatography (HPLC) methods for analysis of formaldehyde. This study was conducted to develop a convenient derivatization method for cosmetics by improving complex pre-treatment procedures included in KFDA method. To simplify pre-treatment procedures of KFDA method, reaction conditions including pH, time and temperature were optimized. This pre-treatment method does not require complicate pre-treatment steps of KFDA method such as pH adjustment of test solution with acetate buffer (pH 5.0), solvent-solvent partitioning with dichloromethane and concentrating procedure with vacuum evaporator. Formaldehyde-dinitrophenylhydrazone (formaldehyde-DNP) product produced by derivatization reaction was separated and quantified with a reversed-phase HPLC, which was slightly modified with KFDA method. The linearity test showed good results with 0.9999 of correlation coefficient ($r^2$) in the range of 2 ~ 40 ppm of standard solutions. In this method, limit of detection (LOD) and limit of quantitation (LOQ) values for formaldehyde were 0.2 ppm and 0.5 ppm, respectively. In addition, recovery test demonstrated that the method was also accurate and reproducible. Therefore, the proposed method can be applicable to rapid analysis of formaldehyde in cosmetics.

• Korean Journal of Weed Science
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• v.12 no.1
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• pp.52-60
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• 1992

There was no significant difference in the final germination percentages(Experiment 1-3) as affected by sunflower root exudates between the control and the treated for the test species. In general(Experiment 1), however, germination onset was delayed the treated bottles. Germination rate was, also, reduced for both radish(Raphanus sativus L.) and rice(Oryza sativa L.). Therefore, the germination index was low in the treated bottles but germination gradually increased with time in the greated bottles in all test species so that the final germination percentages were similar between treatments. The root exudates of sunflower had significant inhibitory effects(Experiment 1-3) on the lengths of the shoots and roots of all the test species. Fresh weight was also significantly reduced in all test species. Sunflower seedlings(Experiment 3) in the treated(with the XAD-4 resin column) were larger and healthier than those in the control (without XAD-4 resin column) because of the removal of allelochemicals. The fresh weight of sunflower seedlings was markedly inhibited by sunflower root exudates. These mean that sunflower probably is an autotoxic crop.

• Journal of the Korean Wood Science and Technology
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• v.45 no.6
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• pp.836-845
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• 2017

Gravimetric method is usually used to evaluate air-dry density, which is governing physical or mechanical properties of wood. Although it had high evaluation accuracy, the method is time consuming process. Thus, this study was conducted to estimate air-dry density of wood with high accuracy by using polychromatic X-ray and digital detector as alternative of gravimetric method. To quantify polychromatic X-ray projection for evaluating air-dry density, Lambert-Beer's law with the integral value of probability function was used. The integral value was used as weighting factor in the law, and it was determined by conducting simple test at various penetration depths and tube voltage. Mass attenuation coefficient (MAC) of wood also calculated by investigating polychromatic X-ray projection according to species, penetration depth and tube voltage. The species had not an effect on change of MAC. Finally, an air-dry density of wood was estimated by applying the integral value, MAC and Lambert-Beer's law to polychromatic X-ray projection. As an example, the relation of the integral value (${\alpha}$) according to penetration depth (t, cm) at tube voltage of 35 kV was ${\alpha}=-0.00091t{\times}0.0184$ while the regression of the MAC (${\mu}$, $cm^2/g$) was ${\mu}=0.5414{\exp}(-0.0734t)$. When calculation of root mean squared error (RMSE) was performed to check the estimation accuracy, RMSE at 35, 45 and 55 kV was 0.010, 0.013 and $0.009g/cm^3$, respectively. However, partial RMSE in relation to air-dry density was varied according to tube voltage. The partial RMSE below air-dry density of $0.41g/cm^3$ was $0.008g/cm^3$ when tube voltage of 35 kV was used. Meanwhile, the partial RMSE above air-dry density of $0.41g/cm^3$ decreased as tube voltage increased. It was conclude that the accuracy of estimation with polychromatic X-ray and digital detector was quite high if the integral value and MAC of wood were determined precisely or a condition of examination was chosen properly. It was seemed that the estimation of air-dry density by using polychromatic X-ray system can supplant the gravimetric method.

• Journal of Korea Water Resources Association
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• v.53 no.4
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• pp.273-283
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• 2020

Quantitative forecasting of groundwater levels for the assessment of groundwater variation and vulnerability is very important. To achieve this purpose, various time series analysis and machine learning techniques have been used. In this study, we developed a prediction model based on LSTM (Long short term memory), one of the artificial neural network (ANN) algorithms, for predicting the daily groundwater level of 11 groundwater wells in Hankyung-myeon, Jeju Island. In general, the groundwater level in Jeju Island is highly autocorrelated with tides and reflected the effects of precipitation. In order to construct an input and output variables based on the characteristics of addressing data, the precipitation data of the corresponding period was added to the groundwater level data. The LSTM neural network was trained using the initial 365-day data showing the four seasons and the remaining data were used for verification to evaluate the fitness of the predictive model. The model was developed using Keras, a Python-based deep learning framework, and the NVIDIA CUDA architecture was implemented to enhance the learning speed. As a result of learning and verifying the groundwater level variation using the LSTM neural network, the coefficient of determination (R²) was 0.98 on average, indicating that the predictive model developed was very accurate.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1601-1607
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• 2013

A determination of circulating tumor cell (CTC) effectiveness for prediction of progression-free survival (PFS) and overall survival (OS) was conducted as an adjunct to standard treatment of care in breast cancer management. Between November 2008 and March 2009, 22 metastatic and 12 early stage breast carcinoma patients, admitted to Ankara Oncology Training and Research Hospital, were included in this prospective trial. Patients' characteristics, treatment schedules and survival data were evaluated. CTC was detected twice by CellSearch method before and 9-12 weeks after the initiation of chemotherapy. A cut-off value equal or greater than 5 cells per 7.5 ml blood sample was considered positive. All patients were female. Median ages were 48.0 (range: 29-65) and 52.5 (range: 35-66) in early stage and metastatic subgroups, respectively. CTC was positive in 3 (13.6%) patients before chemotherapy and 6 (27.3%) patients during chemotherapy in the metastatic subgroup whereas positive in only one patient in the early stage subgroup before and during chemotherapy. The median follow-up was 22.0 (range: 21-23) and 19.0 (range: 5-23) months in the early stage and metastatic groups, respectively. In the metastatic group, both median PFS and OS were significantly shorter in any time CTC positive patients compared to CTC negative patients (PFS: 4.0 vs 14.0 months, Log-Rank p=0.013; and OS: 8.0 months vs. 20.5 months, Log-Rank p<0.001). OS was affected from multiple visceral metastatic sites (p=0.055) and higher grade (p=0.044) besides CTC positivity (log rank p<0.001). Radiological response of chemotherapy was also correlated with better survival (p<0.001). As a result, CTC positivity was confirmed as a prospective marker even in a small patient population, in this single center study. Measurement of CTC by CellSearch method in metastatic breast carcinoma cases may allow indications of early risk of relapse or death with even as few as two measurements during a chemotherapy program, but this finding should be confirmed with prospective trials in larger study populations.

• Journal of fish pathology
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• v.5 no.2
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• pp.135-142
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• 1992

The absorption and excretion times of oxolinic acid(OX) used in farms as new aquatic antibiotics commonly were evaluated with determination of the effects of water temperature and feeding to parameters by using the bioassay technique. On the same time, antibacterial activity and the complex formation of oxolinic acid with serum proteins of two different fishes were compared to those oxytetracycline(OTC). With more than 10 times lower MIC values than those of OTC in the strains among 13 analyzed fish pathogens. OX did not show the decresed antibacterial activity by the binding of serum proteins in carp and tilapia. It implies more powerful potential of OX as aquatic medicine OTC. The serum concentration of OX after different administrations the oral, i.m., i.v and dipping methods were compared. The higher beginning concentration in serum and faster excretion times were obserbed in i.m. and dipping methods respectively. In the oral and i.m. administration, peak serum concentration after 24－48 hrs and slow excretion times demonstrated in both methods. These pharmacokinetic characteristics similar at $30^{\circ}C$ and $20^{\circ}C$ water temperature conditions, however, beginning serum concentration of OX in fish dipped in $50mg/\ell$ sol after starvation for 2 wks was appeared lower than those of fed fish. It suggests the importance of biological condition of the gill or skin for absorption of antibiotics after dipping administration.

• Journal of Environmental Health Sciences
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• v.44 no.4
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• pp.397-407
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• 2018

Objectives: The purpose of this study is to investigate human health risk assessment of indoor air pollutants at small-sized public-use facilities (e.g., daycare centers, hospital and elderly care facilities) that the susceptible population is mainly used. Methods: To assess indoor air quality (IAQ), the concentrations of indoor air contaminants such as HCHO, benzene, toluene, ethylbenzene, xylene, styrene, PM-10, CO, $NO_2$ and $O_3$ in air samples were measured according to the Indoor Air Quality Standard Method. By conducting the questionnaire survey, the major factors influencing IAQ were identified. Human health risk assessment was carried out in the consideration of type of use (user and worker) at 75 daycare centers, 34 hospitals and 40 elderly care facilities. Results: As a result of measurement of indoor air contaminants, the average concentration of HCHO and TVOCs in hospitals was higher than daycare centers and elderly care facilities, about 8.8 and 23.5% of hospitals were exceeded by IAQ standard. In human health risk assessment, for the user of daycare centers and elderly care facilities, the mean carcinogenic risk of HCHO inhalation was higher than acceptable value. Except for HCHO, other values were determined under acceptable risk. Similarly, for the worker of hospitals, the mean carcinogenic risk of HCHO inhalation was higher than acceptable value and other values were evaluated under acceptable risk. In contrast, the risk levels of other contaminants measured in elderly care facilities were acceptable. In the determination of factors influencing IAQ, the construction year, building type, ventilation time, and the use of air cleaner were identified. Conclusions: This study provides the information for establishing the plans of public health management of IAQ at small-sized public-use facilities that have not yet been placed under the regulation. The findings suggest the consideration of human health risk assessment results for the IAQ standards.

• Journal of the Korean earth science society
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• v.34 no.7
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• pp.626-632
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• 2013

In this study the GPS Precipitable Water Vapor (PWV) was derived and evaluated by a radiosode measure during the winter intensive observation in Gangneung site from January 5 till February 29 in 2012. Bernise 5.0 software was used to derive the GPS data. GPS-derived PWV from Zero difference (GANG) and Single difference (GANG and DAEJ) was high variance in time and about 5 times the PWV of radiosonde. GPS post-processing has been performed from two additional IGS site (Xian Dao, Ibaraki-ken) in order to correct the absolute troposphere errors. As a result, the mean bias error (MBE) and root mean square error (RMSE) and correlation compared with radiosonde measure were 0.67 mm, 6.40 mm, and 0.93, respectively. In order to correct the relative troposphere errors from the altitudinal difference between the two GPS receivers, we calculated the GPS-derived PWV by adding the data of GPS that was installed in Gangneung-Wonju University near the Gangwon Regional Meteorological Administration. In the end, the improved result showed that MBE, RMSE and correlation in comparison with radiosonde measures were 0.61 mm, 5.79 mm, and 0.93, respectively.

• Journal of Periodontal and Implant Science
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• v.47 no.4
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• pp.211-218
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• 2017

Purpose: The purpose of the present study was to perform a pattern analysis in patients with temporomandibular disorder (TMD) resulting from unilateral mastication due to chronic periodontitis. Methods: Thirty participants with signs or symptoms of TMD who engaged in unilateral mastication due to periodontitis-related discomfort (test group) were selected. Another 30 subjects exhibiting signs or symptoms of TMD resulting from unilateral mastication not due to chronic periodontitis (control group) were also recruited. An interview-based questionnaire was administered, and an examination of the temporomandibular joint (TMJ) with determination of periodontal status was performed. Results: The duration of unilateral mastication was significantly longer in the control group than in the test group. There was a significant negative correlation between the duration of unilateral mastication and the Community Periodontal Index score. Using the Research Diagnostic Criteria for TMD (RDC/TMD) axis I algorithms, all the subjects were assigned to 3 main groups. The test group exhibited significantly a higher diagnostic distribution of group III (arthralgia, osteoarthritis, or osteoarthrosis), and in both the test and control groups, the number of diagnoses was larger for the non-chewing side. The control group showed a significantly higher diagnostic distribution of group I (myofacial pain), and in both the test and control groups, the number of diagnoses was larger for the chewing side. Conclusions: The results of the present study indicate that unilateral mastication due to chronic periodontitis could induce not only pain but also structural TMJ changes if adequate treatment is not administered and supported within a short time from the onset of the condition. Therefore, immediate treatment of chronic periodontitis is recommended to prevent not only the primary progress of periodontal disease, but also secondary TMJ-related problems. Furthermore, subjects who have suffered chronic long-term periodontitis without treatment should be urged to undergo a TMJ examination.