• Title/Summary/Keyword: Three Han

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An NMR study on the intrinsically disordered core transactivation domain of human glucocorticoid receptor

  • Kim, Do-Hyoung;Wright, Anthony;Han, Kyou-Hoon
    • BMB Reports
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    • v.50 no.10
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    • pp.522-527
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    • 2017
  • A large number of transcriptional activation domains (TADs) are intrinsically unstructured, meaning they are devoid of a three-dimensional structure. The fact that these TADs are transcriptionally active without forming a 3-D structure raises the question of what features in these domains enable them to function. One of two TADs in human glucocorticoid receptor (hGR) is located at its N-terminus and is responsible for ~70% of the transcriptional activity of hGR. This 58-residue intrinsically-disordered TAD, named tau1c in an earlier study, was shown to form three helices under trifluoroethanol, which might be important for its activity. We carried out heteronuclear multi-dimensional NMR experiments on hGR tau1c in a more physiological aqueous buffer solution and found that it forms three helices that are ~30% pre-populated. Since pre-populated helices in several TADs were shown to be key elements for transcriptional activity, the three pre-formed helices in hGR tau1c delineated in this study should be critical determinants of the transcriptional activity of hGR. The presence of pre-structured helices in hGR tau1c strongly suggests that the existence of pre-structured motifs in target-unbound TADs is a very broad phenomenon.

Investigation of the Voltage Collapse Mechanism in Three-Phase PWM Rectifiers

  • Ren, Chunguang;Li, Huipeng;Yang, Yu;Han, Xiaoqing;Wang, Peng
    • Journal of Power Electronics
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    • v.17 no.5
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    • pp.1268-1277
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    • 2017
  • Three-phase pulse width modulation (PWM) rectifiers are usually designed under the assumption of ideal ac power supply and input inductance. However, non-ideal circuit parameters may lead to a voltage collapse of PWM rectifiers. This paper investigates the mechanism of voltage collapse in three-phase PWM rectifiers. An analytical stability boundary expression is derived by analyzing the equilibrium point of the averaging state space model, which can not only accurately locate the voltage collapse boundary in the circuit parameter domain, but also reveal the essential characteristic of the voltage collapse. Results are obtained and compared with those of the trial-error method and the Jacobian method. Based on the analysis results, the system parameters can be divided into two categories. One of these categories affects the critical point, and other affects only the instability process. Furthermore, an effective control strategy is proposed to prevent a vulnerable system from being driven into the instability region. The analysis results are verified by the experiments.

A Study On Steering System for Mobile Robot with Permanent Magnet Wheels (영구자석 바퀴를 이용한 이동 로봇의 조향 시스템 연구)

  • Kim Jin-Gak;Yi Hwa-Cho;Han Seung-Chul
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.311-312
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    • 2006
  • In this paper, steering systems for mobile robot with permanent magnet wheels are discussed. The mobile robot with permanent magnet wheels can have three different types of steering and driving configurations; two-wheels, three-wheels, four-wheels. By a Two-WD(Wheel Driving) system, driving and steering characteristics are controlled by ratio of each wheel speeds. Three-WD system is steered by a front wheel and driven by rear wheels. Four-WD system has better stability than two wheel system. Usually the permanent magnet wheel has nearly none slip. Thus turning radius of the mobile robot with three-WD and four-WD System will be increased and the steering and driving system will be complicated. To solve this problem, two magnet wheels with two dummy wheels are used in this study. fuming radius of the developed mobile robot is small and the structure of the robot is simple. It is possible to move forward, backward, to turn left and right, and to rotate freely with two-WD. This study proved that two-WD system is very suitable fur the mobile robot with permanent magnet wheels.

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Design of Force Measuring System for Deburring Using Industrial Robot (산업용로봇을 이용한 디버링을 위한 힘측정시스템 설계)

  • Lee, Gyeong Jun;Kim, Han Sol;Kim, Chong Jin;Kim, Hyeon Min;Kim, Gab Soon
    • Journal of the Korean Society for Precision Engineering
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    • v.32 no.7
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    • pp.653-660
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    • 2015
  • This paper describes the design of the force measuring system for an industrial robot's deburring work. The force measuring system is composed of a three-axis force sensor, a measuring device, a housing and a cover. The three-axis force sensor can detect x-direction force, y-direction force and z-direction force at the same time. The measuring device is designed using DSP(Digital Signal Processor), and have a RS-232 and a RS-485 communication port for sending force data to PC or other controller. As a result of test, the repeatability error and the non-lineality error of the three-axis force sensor are less than 0.03%, and the interference error of the sensor is less than 0.95%. It is thought that the force measuring system can be used for an industrial robot's deburring work.

Relationships between child’s temperament and behavior problem (아동의 기질과 문제행동과의 관계)

  • 정현희;최경순
    • Journal of Families and Better Life
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    • v.19 no.5
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    • pp.1-14
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    • 2001
  • The purpose of this study was to examine the relationships between child’s temperament and behavior problem according to child’s sex. The subjects for this study were children’s mothers of 2nd grade selected from elementary schools in Busan. Han, Sae-Young’s questionnaires(1996) on child’s temperament and Kim, Min-Kyung’s questionnaires(1998) on child’s behavior problem were used. Statistical techniques such as t-test, Pearson’s correlation, multiple regression, canonical were used. The results were as follows : (1) According to sex, there were no significant differences in child’s temperament. But there were significant differences in child’s behavior problem. The boys got higher scores than girls in hyperactive/distractive behavior and in hostile/aggressive behavior. (2) There were significant correlations between child’s emotionality and hyperactive/distractive behavior, between child’s emotionality and anxious/fearful behavior, between child’s emotionality and hostile/ aggressive behavior, and between child’s activity and hyperactive/distractive behavior. (3) The predicted variables for child’s hyperactive/distractive behavior were emotionality and activity. The predicted variable for chid’s anxious/fearful behavior and hostile/aggressive behavior was emotionality. (4) Among three dimensions of boy’s temperament, the effective variable was emotionality. And among three dimensions of boy’s behavior problem were anxious/fearful behavior and hostile/aggressive behavior. Among three dimensions of girl’s temperament, the effective variable was emotionality. And among three dimensions of girl’s problem behavior was anxious/fearful behavior. Implications of this study were discussed in terms of child’s temperament and behavior problem.

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The reliability of an easy measuring method for abutment convergence angle with a computer-aided design (CAD) system

  • Seo, Yong-Joon;Kwon, Taek-Ka;Han, Jung-Suk;Lee, Jai-Bong;Kim, Sung-Hun;Yeo, In-Sung
    • The Journal of Advanced Prosthodontics
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    • v.6 no.3
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    • pp.185-193
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    • 2014
  • PURPOSE. The purpose of this study was to evaluate the intra-rater reliability and inter-rater reliability of three different methods using a drawing protractor, a digital protractor after tracing, and a CAD system. MATERIALS AND METHODS. Twenty-four artificial abutments that had been prepared by dental students were used in this study. Three dental students measured the convergence angles by each method three times. Bland-Altman plots were applied to examine the overall reliability by comparing the traditional tracing method with a new method using the CAD system. Intraclass Correlation Coefficients (ICC) evaluated intra-rater reliability and inter-rater reliability. RESULTS. All three methods exhibited high intra-rater and inter-rater reliability (ICC>0.80, P<.05). Measurements with the CAD system showed the highest intra-rater reliability. In addition, it showed improved inter-rater reliability compared with the traditional tracing methods. CONCLUSION. Based on the results of this study, the CAD system may be an easy and reliable tool for measuring the abutment convergence angle.

Review of Clinical Trials on Aromatherapy in PubMed (PubMed 검색을 통해 살펴본 Aromatherapy의 임상연구동향에 관한 고찰)

  • Han, Eun-Jeung;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.15 no.1
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    • pp.276-284
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    • 2002
  • Aromatherapy is becoming increasingly popular, however there are few clear indications for its use. To systematically review the clinical studies on aromatherapy, computcrized literature searches were performed from PubMed. Fourteen trials were located. The conclusions were as follows: 1. All the trials were published after 1993. 2. To analyze the publication journals, five of fourteen trials were on nursing, three of them on neuropsychiatry and one on dermatology. 3. Most widely used indications of aromatherapy were on general physical, psychological and physiological field. 4. On the procedure of aromatherapy, eight of them were by massage, three by inhalation, one by massage & inhalation and one by bath additive. 5. To analyze the publication type, all fourteen trials were clinical trials. Twelve of them were randomized controlled trials. Two of them were using single subject design. 6. To observe the sample size, five of them were under 10, four from 10 to 50, two from 50 to 100 and three above 100. 7. Eleven of fourteen trials were using inferential statistics. Eight of the eleven trials were significantly effective, but three had no statistical significance.

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An Experimental Study for the Qualitative Effect of Carrier Pin Hole Position Error on Planet Load Sharing of Wind Turbine Three-point Suspension Gearbox (풍력발전기용 3점 지지 기어박스에서 캐리어 핀홀 위치 오차가 유성기어의 하중분할에 미치는 정성적 영향에 관한 실험적 연구)

  • Nam, Ju-Seok;Han, Jeong-Woo
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.25 no.2
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    • pp.97-104
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    • 2016
  • In this study, the qualitative effects of the positional error of carrier pin holes on the planet load sharing characteristics of the three-point suspension gearbox of wind turbines were investigated experimentally. A 35-kW gearbox comprising two planetary gear stages and a parallel gear stage and size one-fourth of that of a 2-MW three-point suspension gearbox was used as the test gearbox. The strain gauges attached to the ring gear teeth of the input planetary gear stage were used for the purpose of this study. The applied loading conditions were 50%, 75%, and 100% of the rated torque, and the mesh load factor was used as the load sharing index. The experimental results indicated that both the magnitude and direction of the positional error of pin holes had a significant effect on the planet load sharing characteristics of the three-point suspension gearbox. In addition, an increase in the applied torque results in uniform load sharing.

Study on the Forest Watershed Classification Method for Forest Watershed Management

  • Kim, Han Soo;Lee, Yang Ju
    • Korean Journal of Environment and Ecology
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    • v.29 no.2
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    • pp.236-249
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    • 2015
  • The master plan of forest land management proposes forest watershed management that considers regional characteristics in order to overcome the problem of uniform forest land management. In order to manage the forest watersheds in Gyeonggi-do, this study classified 1,823 forest watersheds in Gyeonggi-do and attempted to understand their characteristics. It conducted a factor analysis and cluster analysis from the perspective of conservation value and development pressure using forest land indicators. In terms of conservation value, three factors were drawn: the topography factor, vegetation factor and public service factor, while in terms of development pressure, three factors were drawn: the easiness of development factor, economic benefits factor and development activity factor. Using these factors, forest watersheds were divided into three clusters in terms of conservation value while they were divided into three clusters in terms of development pressure. Using the results of the cluster analysis from a conservation-development perspective, the forest watersheds were classified into nine different types, and the characteristics were identified by each type. It is judged that the factors and clusters drawn as a result of the research accurately reflect the present conditions of Gyeonggi-do, and the nine types of forest watersheds have clear characteristics according to each type, which are judged to be utilized in forest management in the future.

The Development of Portable Rotor Bar Fault Diagnosis System for Three Phase Small Induction Motors Using LabVIEW (LaVIEW를 이용한 휴대용 3상 소형유도전동기 회전자 바 고장 진단 시스템 개발)

  • Song, Myung-Hyun;Park, Kyu-Nam;Han, Dong-Gi;Lee, Tae-Hun;Woo, Hyeok-Jae
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.56 no.1
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    • pp.51-55
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    • 2007
  • In this paper, a portable rotor bar fault diagnosis system for small 3 phase induction motors is suggested. For portable real-tine diagnosis system, an USB-DAQ board for collecting the 3 phase current data, three current probes, and a notebook computer are used. The LabVIEW graphical language is used for filtering, analysis, storing, and monitoring the current data. The three phase stator current are filtered and transformed to frequency level by FIT. An analysis window programed by LabVIEW is located in front panel to show the FIT results and this suggested window has a zooming function to detect the fault feature more easily near the feature frequency range which is varying by the slip frequency. To show the possibility of portable rotor bar diagnosis system, three types(healthy, one rotor bar fault, two rotor bar fault) of rotor bar are intentionally prepared and compared by the suggested window of front panel. Experimental results are shown that a suggested diagnosis system is applicable to portable diagnosis system and the rotor bar fault is detected by the frequency window in front panel programed in LabVIEW graphical language.