• Fisheries and Aquatic Sciences
• /
• 제12권3호
• /
• pp.179-184
• /
• 2009

Hemibarbus mylodon (Cypriniformes) is an endemic freshwater fish species in the Korean peninsula, for which urgent conservation efforts are needed. To understand their stress responses in relation to metal toxicity and thermal elevation, we performed a real-time RT-PCR-based expression assay of hepatic copper/zinc-superoxide dismutase (Cu/Zn-SOD), a key antioxidant enzyme, in response to experimental heavy metal exposure or heat treatment. The transcription of hepatic Cu/Zn-SOD was differentially modulated by acute exposure to Cu, cadmium (Cd), or Zn. Exposure to each metal at $5{\mu}M$ for 24 h revealed that Cu stimulated the mRNA expression of Cu/Zn-SOD to a greater extent than the other two heavy metals. The elevation in Cu/Zn-SOD transcripts in response to Cu exposure was dose-dependent (0.5 to $5{\mu}M$). Time course analysis of Cu/Zn-SOD expression in response to Cd exposure ($5{\mu}M$) revealed a transient pattern up to day 7. Exposure to thermal stress (an increase from 22 to $30^{\circ}C$ at a rate of $1^{\circ}C/h$ followed by $30^{\circ}C$ for 18 h) did not significantly alter SOD transcription, although heat shock protein 90 kDa (HSP90) transcription was positively correlated with an increase in temperature.

• Fisheries and Aquatic Sciences
• /
• 제18권2호
• /
• pp.195-202
• /
• 2015

The effects of waterborne arsenic (As) exposure on bioaccumulation and antioxidant defenses were examined in the liver and gills of tilapia, Oreochromis niloticus, under thermal stress. Tilapia were exposed to different As concentrations (0, 200, and $400{\mu}g\;L^{-1}$) at three water temperatures (20, 25, and $30^{\circ}C$) for 20 days. After As exposure, higher levels of As accumulation were observed in the gills compared with the liver in elevated water temperatures. In terms of the antioxidant response, glutathione (GSH) levels and the activities of glutathione reductase (GR), glutathione peroxidase (GPx), and glutathione S-transferase (GST) significantly decreased in the liver and gills of tilapia exposed to As for 20 days, regardless of the As concentration (200 and $400{\mu}g\;L^{-1}$) or water temperature. These enzyme activities exhibited greater fluctuations in the liver and gills of tilapia after As exposure in water warmer than $20^{\circ}C$. The present findings suggest that the simultaneous stress of temperature change and As exposure can accelerate As accumulation and alter the antioxidant enzymes activities of tilapia.

• 대한방사선기술학회지:방사선기술과학
• /
• 제31권4호
• /
• pp.415-417
• /
• 2008

현재 방사선치료는 선형가속기에 의하여 대다수 이루어지고 있으며 사용되는 방사선인 광자도 의학의 발전에 의해 고에너지화 고선량화 되고 있다. 본 연구에서는 방사선치료 조사면에서 중성자 측정이 가능한 CR-39를 이용한 중성자 검출법을 이용하였다. 선형가속기에서 발생되는 X선(광자)치료 시 발생 되는 중성자의 선량을 CR-39를 이용한 중성자 검출법을 이용하여 측정하고, 임상적 응용으로 고에너지 광자를 이용하여 암 치료에 사용할 때 중성자의 발생이 환자치료 선량과 연관되는 어떤 문제를 발생시키는지를 연구한 결과는 다음과 같다. 속중성자의 경우 광자 1Gy 조사 시 평균 0.35mSv, 2Gy 조사 시 평균 0.65mSv, 5Gy 조사 시 평균 1.82mSv, 열중성자의 경우 광자 1Gy 조사 시 평균 0.26mSv, 2Gy 조사 시 평균 0.56mSv, 5Gy 조사 시평균 1.23mSv의 중성자 발생하였다. Wedge Filter를 사용하여 중성자의 발생을 측정한 결과 Wedge Filter를 사용했을 때 중성자의 발생이 증가하였다. 고선량을 요구하는 SRS Cone을 사용했을 때에는 기존의 실험결과 보다 많은 중성자가 검출되었다. 속중성자의 경우 광자 5Gy 조사 시 평균 2.85mSv, 열중성자의 경우 광자 5Gy 조사 시 평균 1.37mSv의 중성자가 발생하였다. 일반 치료 시 광자 5Gy 조사했을 때 보다 속중성자의 경우 약 1.6배, 열중성자의 경우 약 1.12배 정도의 중성자가 더 발생하는 것으로 나타났다.

• 한국세라믹학회지
• /
• 제54권4호
• /
• pp.314-322
• /
• 2017

This study investigates changes in the mechanical behavior, such as changes in indentation load-displacement curve, wear resistance and contact fatigue resistance of thermal barrier coatings (TBCs) by thermal cycling test and thermal shock test. Relatively dense and porous TBCs on nickel-based bondcoat/superalloy are prepared; the highest temperature applied during thermal durability test is $1350^{\circ}C$. The results indicate that the porous TBCs have relatively longer lifetime during thermal cycling and thermal shock tests, while denser TBCs have relatively higher wear and contact fatigue resistance. The mechanical behavior is influenced by sintering of the TBCs by exposure to high temperature during tests.

• Composites Research
• /
• 제30권6호
• /
• pp.422-428
• /
• 2017

본 연구에서는 온도와 수분에 노출된 다중벽 탄소나노튜브가 함유된 나노복합재의 수분흡수거동, 인장특성, 열분석특성을 평가하였다. 이때 탄소나노튜브 함유량은 0 wt%, 1 wt%, 2 wt%를 고려하였으며 시편은 각각 $25^{\circ}C$와 $75^{\circ}C$의 침수조건에 600시간까지 노출시켰다. 연구결과에 따르면 수분흡수량은 노출시간이 길어지면 증가하지만 최대 수분흡수량과 600시간에서의 수분흡수량 차이는 일정하게 나타났다. 인장탄성계수는 노출시간이 길어지면 낮아지고 탄소나노튜브 함유량이 많고 노출온도가 높아지면 감소 정도는 크게 나타났다. 인장강도는 탄소나노튜브가 함유되지 않은 경우 노출시간이 길어지면 감소하지만 MWCNT 함유되면 MWCNT의 보강 효과로 인해 증가하는 양상이 나타났다. 저장탄성계수, 유리전이온도, $tan{\delta}$ 피크 크기는 노출시간이 길어지면 낮게 나타나며 높은 노출온도에 300시간 이상 노출되면 두 개의 피크를 갖는 $tan{\delta}$ 선도가 나타났다.

• 한국산업보건학회지
• /
• 제24권3호
• /
• pp.256-262
• /
• 2014

Objectives: The purpose of this study was to identify the major volatile organic compounds generated during extrusion work with nylon 66 resin and evaluate causes of discomfort among extrusion workers. Methods: A thermal decomposition experiment using nylon 66 resin collected at a worksite was conducted in the laboratory. Based on hazards identified through the thermal decomposition experiment, the exposure levels of the workers were evaluated. Results: The major decomposition products were formaldehyde, acetaldehyde, aniline, cyclopentanone and diphenyl amine. These materials were identical to those sampled in the extrusion booth. The sources of the annoying smells, about which the workers had complained, were formaldehyde, aniline, diphenyl amine, and other hazards in the vapor and fine particles produced by the extrusion work. Formaldehyde, acetaldehyde, and aniline were detected from air samples among workers involved in extrusion work. However, the concentration levels were much lower than Korean occupational exposure limits. The average concentration levels of formaldehyde, acetaldehyde, and aniline were 0.0120 ppm, 0.0036 ppm and 0.0006 ppm, respectively. Conclusions: The extrusion process at around $300^{\circ}C$ thermally decomposes the nylon 66 resin, emitting formaldehyde, aniline, and other hazards, which might have made workers uncomfortable due to their smells. The workers exposure levels to volatile organic compounds were far lower than Korean occupational exposure limits. However, since formaldehyde is a human carcinogen and acetaldehyde and aniline are also confirmed animal carcinogens, it is recommended that exposure levels should be maintained at a minimum level.

• Nuclear Engineering and Technology
• /
• 제5권4호
• /
• pp.291-309
• /
• 1973

TRIGA Mark II와 III 원자로의 여러가지 가동조건에 있어서 노벽으로 부터의 누설 ${\gamma}$선에 의한 조사선양률을 3"$\times$3"원통형 NaI(T1) 섬광계수기와 400 channel파 고분석장치로 측정하였는데 측정된 spectrum으로부터 조사선양률을 산출하는데는 실제적면에서 복잡하기 짝이 없는 response matrix 방법대신 정도가 좋으면서도 비교적 그 과정이 단순한 Moriuchi의 specturm -조사선양률 환산 이론을 적용하였다. 연구결과에 따르면 노심에서 발생된 누설 ${\gamma}$선의 기본적인 spectrum 형태는 원자로의 열출력이나 차장벽에 의한 강도의 감쇠에 별로 영향을 받지 않고 있으며 원자로 누설${\gamma}$선에 의란 전조사선양률의 공기중에서의 감쇠는 폭 넓은 energy분포에도 불구하고 지수함수적 감쇠를 하고 있음이 판명되있다. 이 전조사선양률은 원자로의 열출력에 대체로 비례하고 있으나 TRIGA Mark III과 같은 가동형노심의 경우는 측정된 spectrum이 매우 다양한바, 그로부터 산출된 전조사선양률의 크기에는 관계없이, spectrum 분해방법을 적용하여 노심에서 발생된 누설 ${\gamma}$선과 원자로가동중 발생되는 여지 ${\gamma}$선의 기여를 판별 해석하는데 성공하였다.

• 한국신뢰성학회지:신뢰성응용연구
• /
• 제17권1호
• /
• pp.78-82
• /
• 2017

Purpose: The purpose of this study is to evaluate failure characteristic and mechanism of four commercial water-repellent coatings for elevated temperature machinery applications. Method: Thermal degradation was performed for up to 64 thermal cycles. 1 cycle consists of 15 minute holding at 523K under 300rpm revolution and 15 minute-natural cooling. Contact angle was measured and microstructure of the coating layer was observed by using a scanning electron microscope. Results: Four kinds of commercial repellent coating showed hydrophobic or super-hydrophobic property implying that all coatings are suitable for room temperature application. Contact angle of three kinds of commercial coatings decreased rapidly after thermal exposure, while only one specimen having hydrophobic surface showed extremely slow degradation. Conclusion: Observed decrease in contact angle of the coatings were attributed to formation of macro-sized pores and disappearance of micro-protrusion during thermal exposure. Optimum water-repellent coating needs to be selected under the consideration of initial contact angle as sell as service temperature.

• Journal of the Korean Physical Society
• /
• 제73권9호
• /
• pp.1289-1294
• /
• 2018

The present study aims to investigate experimentally and theoretically thermal ablation in soft tissues by using high intensity focused ultrasound (HIFU) to assess tissue damage during HIFU thermotherapy. The HIFU field was calculated by solving the axisymmetric Khokhlov-Zabolotskaya-Kuznetsov equation from the frequency-domain perspective. The temperature field was calculated by solving Pennes' bioheat transfer equation, and the thermal dose required to create a thermal lesion was calculated by using the thermal dose formula based on the thermal dose of a 240-min exposure at $43^{\circ}C$. In order to validate the simulation results, we performed thermal ablation experiments in a tissue-mimicking phantom and ex-vivo porcine liver for two different HIFU source conditions by using a 1.1-MHz, single-element, spherically focused HIFU transducer. The small difference between the measured and the predicted lesion sizes suggests that the implementation of the numerical model used here should be modified to iteratively allow for temperature-dependent changes in the physical properties of tissues.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
• /
• pp.238.2-238.2
• /
• 2015

Surface modification of vertically-aligned carbon nanotube (VACNT) is essential in order to meet specific demands for particular applications such as field emission displays, heat dissipation device and potential sun energy conversion due to their superior electrical and thermal conductivity and strong light absorption. In this study, we observe the effect of exposure to water vapor on a different lengths of the surfaces of VACNT. The study was conducted on three different lengths of the VACNT: short length around $200{\mu}m$, medium-length around $500{\mu}m$, and high length around 1 mm. Water exposure time ranges between 2-10 min and temperature of the water ranges from 60 to 120 oC. The result of water vapor exposure mainly show that increasing the exposure time and water temperature give rise to increase of the speed of change on the surface of the VACNT. Especially, the shorter VACNT change their surface morphology most rapidly.