• 제목/요약/키워드: The state of smoking

검색결과 219건 처리시간 0.037초

Accelerated inflammation in peripheral artery disease patients with periodontitis

  • Kure, Keitetsu;Sato, Hiroki;Aoyama, Norio;Izumi, Yuichi
    • Journal of Periodontal and Implant Science
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    • 제48권6호
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    • pp.337-346
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    • 2018
  • Purpose: Peripheral artery disease (PAD) is a form of arteriosclerosis that occurs in the extremities and involves ischemia. Previous studies have reported that patients with periodontitis are at high risk for PAD. However, the relationship between these 2 diseases has not yet been fully elucidated. In this cross-sectional study, we investigated this relationship by comparing patients with PAD to those with arrhythmia (ARR) as a control group. Methods: A large-scale survey was conducted of patients with cardiovascular disease who visited Tokyo Medical and Dental University Hospital. We investigated their oral condition and dental clinical measurements, including probing pocket depth, bleeding on probing, clinical attachment level, and number of missing teeth; we also collected salivary and subgingival plaque samples and peripheral blood samples. All patients with PAD were extracted from the whole population (n=25), and a matching number of patients with ARR were extracted (n=25). Simultaneously, ARR patients were matched to PAD patients in terms of age, gender, prevalence of diabetes, hypertension, dyslipidemia, obesity, and the smoking rate (n=25 in both groups). Real-time polymerase chain reaction was performed to measure the bacterial counts, while the enzyme-linked immunosorbent assay method was used to measure anti-bacterial antibody titers and proinflammatory cytokine levels in serum. Results: PAD patients had more missing teeth ($18.4{\pm}2.0$) and higher serum levels of C-reactive protein ($1.57{\pm}0.85mg/dL$) and tumor necrosis factor-alpha ($70.3{\pm}5.7pg/mL$) than ARR patients ($12.0{\pm}1.7$, $0.38{\pm}0.21mg/dL$, and $39.3{\pm}4.5pg/mL$, respectively). Meanwhile, no statistically significant differences were found in other dental clinical measurements, bacterial antibody titers, or bacterial counts between the 2 groups. Conclusions: Our findings suggested that PAD patients had poorer oral and periodontal state with enhanced systemic inflammation.

노인의 인지감퇴에 미치는 아포지단백 E4와 교육수준의 상호작용 (Interaction of Apolipoprotein E ${\varepsilon}4$ and Education on Cognitive Decline in Korean Elders)

  • 김재민;신일선;김성완;양수진;박상욱;신희영;윤진상
    • 생물정신의학
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    • 제15권1호
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    • pp.29-34
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    • 2008
  • Objectives : This study aimed to test potential modifying effects of education on the association between apolipoprotein E ${\varepsilon}4$ (Apo E4) and cognitive decline. Methods : A community cohort(N=683) aged 65 or over completed the Korean version of Mini-Mental State Examination(MMSE-K) at baseline and two years later(1999-2001). Apo E polymorphisms were genotyped, and classified into that with or without Apo E4. Educational levels were categorized into people with or without education. Covariates included demographic(age, gender), life style(smoking, alcohol drinking), clinical (depression, sleep disorder, vascular risk factors) characteristics. Results : The association between Apo E4 and cognitive decline was significant only in the old persons with no education. The interaction term between education and Apo E4 on cognitive decline was significant(p=0.040). Conclusion : Elders with no education might be more vulnerable to the impact of Apo E4 on cognitive decline, which suggests gene-environment interaction.

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Results of Intravesical Chemo-Hyperthermia in High-risk Non-muscle Invasive Bladder Cancer

  • Ekin, Rahmi Gokhan;Akarken, Ilker;Cakmak, Ozgur;Tarhan, Huseyin;Celik, Orcun;Ilbey, Yusuf Ozlem;Divrik, Rauf Taner;Zorlu, Ferruh
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권8호
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    • pp.3241-3245
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    • 2015
  • Purpose: To examine the effectiveness of mitomycin-C and chemo-hyperthermia in combination for patients with high-risk non-muscle-invasive bladder cancer. Materials and Methods: Between November 2011-September 2013, 43 patients with high-risk non-muscle-invasive bladder cancer undergoing adjuvant chemo-hyperthermia in two centers were evaluated retrospectively. Treatment consisted of 6 weekly sessions, followed by 6 sessions. Recurrence and progression rate, recurrence-free interval and side effects were examined. Analyzed factors included age, gender, smoking status, AB0 blood group, body mass index, T stage and grade, concominant CIS assets. The associations between predictors and recurrence were assessed using multivariate Cox proportional hazard analyses. Results: A total of 40 patients completed induction therapy. Thirteen (32.5%) were diagnosed with tumor recurrence. Median follow-up was 30 months (range 9-39). Median recurrence-free survival was 23 months (range 6-36). The Kaplan-Meier-estimated recurrence-free rates for the entire group at 12 and 24 months were 82% and 61%. There was no statistically significant difference between patient subgroups. Cox hazard analyses showed that an A blood type (OR=6.23, p=0.031) was an independent predictor of recurrence-free. Adverse effects were seen in 53% of patients and these were frequently grades 1 and 2. Conclusions: Intravesical therapy with combination of mitomycin-C and chemohyperthermia seems to be appropriate in high-risk patients with non-muscle-invasive bladder cancer who cannot tolerate or have contraindications for standard BCG therapy.

간호 대학생의 스트레스와 건강통제위 (The Relationships between Stress and Health Locus of Control in Nursing College Students)

  • 차남현
    • 동서간호학연구지
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    • 제19권2호
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    • pp.177-185
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    • 2013
  • Purpose: This study was to identify the relations between stress and health locus of control in nursing college students. Methods: A total of 243 subjects aged between 17 and 27 were selected through convenient sampling. Data were collected with a self reported questionnaire from March 2 to 25, 2013. Collected data were analyzed with SPSS/PC Win 15.0. Results: Differences in stress and health locus of control according to general characteristics were as follows. Stress were significantly different according to gender (t=-2.51, p<.05), grade (F=5.40, p<.01), school record (F=5.72, p<.01), stress solving methods (F=2.62, p<.05). Internal health locus of control was significantly different according to gender (t=2.30, p<.05), grade (F=14.73, p<.001), religion (F=4.63, p<.01), school record (F=5.29, p<.01), economic state (F=5.50, p<.001) and smoking (F=4.17, p<.05). Chance health locus of control was significantly different according to sibling rank (F=2.86, p<.05). Except chance health locus of control, internal heath locus of control and dependence health locus of control have a negative correlation with stress. 15.6% of variance in stress was explained by dependence health locus of control, chance health locus of control, and grade. Conclusion: The findings of this study may be useful in understanding the stress expression of nursing college students and developing more specific programs on personality and self-control.

도시.농촌 지역 초등학생의 가족환경, 건강행위 및 건강상태에 관한 비교 (Comparision of Family Environment, Health Behavior and Health State of Elementary Students in Urban and Rural Areas)

  • 배연숙;박경민
    • 지역사회간호학회지
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    • 제9권2호
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    • pp.502-517
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    • 1998
  • This research intends to survey family environment, health behavior and health status of the students in urban-rural elementary schools and analyze those factors comparatively, and use the result as basic material for school health teacher to teach health education in connection with family and regional areas. It also intends to improve a pupil's self-abilitiy in health care. The subjects involve 2,774 students of urban elementary schools and 583 student in rural ones, who were selected by means of a multi -stage probability sampling. Using the questionnaire and school documents, we collected data on family environment, health behavior and health status for 19 days. Feb. 2nd 1998 through Feb. 20th 1998. The R -form of Family Environment Scale (Moos, 1974) was used in the analysis of family environment(Cronbach's Alpha =0.80). Questionnaires of Health Behavior in School-aged children used by the WHO in Europe(Aaro et al., 1986) and the ones developed by the Health Promotion Committee of the Western Pacific(WHO, 1995)(adapted by long Young-suk and Moon Young-hee(1996)) were used in the analysis of health behavior, as well documents on absences due to sickness, school health room-visits, levels of physical strength, height, weight and degree of obesity were used to determine health status. In next step, We used them with an $X^2$-test, t-test, Odds Ratio, and a 95% Confidence Interval. 1. In two dimensions of three, family-relationship (t=3.41, p=0.001) and system -maintenances(t= 2.41, p=0.0l6) the mean score of urban children were significantly higher than those of rural ones. In the personal development dimension however, there was little significant difference. Assorting family environment into 10 sub-fields and analyzing them, we recognized that urban children were superior to rural children in the sub-fields of expressiveness (t =3.47, p=0.001), conflict (t=0.48, p=0.001), active-recreational orientation (t = 1.97, p=0.049) and organization (t=4.33, p=0.000). 2. Referring to the Odds Ratios of urban-rural children's health behaviors, urban children set up more desirable behavior than rural children wear ing safety belts (Odds Ratio =0.32, p=0.000), washing hands after meals(Odds Ratio = 0.43, p= 0.000), washing hands after excreting (Odds Ratio = 0.39, p=O.OOO), washing hands after coming - home ( Odds Ratio = 0.75, p = 0.003), brushing teeth before sleeping(Odds Ratio =0.45, p=0.000), brushing teeth more than once a day (Odds Ratio =0.73, p=0.0l2), drinking boiled water (Odds Ratio = 0.49, p=0.000), collecting garbage at home(Odds Ratio=0.31, p=0.000) and in the school(Odds Ratio =0. 67, p=0.000). All these led to significant differences. As to taking milk(Odds Ratio = 1.50, p=0.000), taking care of eyesight(Odds Ratio=1.41, p=0.001) and getting physical exercise in(Odds Ratio = 1.33, p=0.0l9) and outside the school(Odds Ratio = 1.32, p=0.005), rural children had more desirable behavior which also revealed a significant difference. There was little significant difference in smoking, but the smoking rate of rural children(5.5%) was larger than that of urban children(3.9%). 3. Health status was analyzed in terms of absences, school health room-visits, levels of physical strength, and the degree of obesity, height and weight. Considering Odds Ratios of the health status of urban-rural children, the health status of rural children was significantly better than that of the urban ones in the level of physical strength(t=1.51, p=0.000) and the degree of obesity(t=1.84, p=0.000). The mean height of urban children ($150.4{\pm}7.5cm$) is taller than that of their counterparts($149.5{\pm}7.9$), which revealed a significant difference (t =2.47, p=0.0l4). The mean weight of urban children($42.9{\pm}8.6kg$) is larger than that of their counterparts($41.8{\pm}9.0kg$), which was also a significant difference(t=2.81, p=0.005). Considering the results above, we can recognize that there are significant differences in family environment, health behavior, and health status in urban-rural children. These results also suggestion ideas for health education. What we would suggest for the health program of elementary schools is that school health teachers should play an active role in promoting the need and importance of health education, develop the appropriate programs which correspond to the regional characteristics, and incorporate them into schools to improve children's ability to manage their own health management.

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Implementation of Smoke-free Legislation in Malaysia: Are Adolescents Protected from Respiratory Health Effects?

  • Zulkifli, Aziemah;Abidin, Najihah Zainol;Abidin, Emilia Zainal;Hashim, Zailina;Rahman, Anita Abd;Rasdi, Irniza;Syed Ismail, Sharifah Norkhadijah;Semple, Sean
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권12호
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    • pp.4815-4821
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    • 2014
  • Background: This study aimed to examine the relationship between respiratory health of Malaysian adolescents with secondhand smoke (SHS) exposure and smoke-free legislation (SFL) implementation. Materials and Methods: A total of 898 students from 21 schools across comprehensive- and partial-SFL states were recruited. SHS exposures and respiratory symptoms were assessed via questionnaire. Prenatal and postnatal SHS exposure information was obtained from parental-completed questionnaire. Results: The prevalence of respiratory symptoms was: 11.9% ever wheeze, 5.6% current wheeze, 22.3% exercise-induced wheeze, 12.4% nocturnal cough, and 13.1% self-reported asthma. SHS exposure was most frequently reported in restaurants. Hierarchical logistic regression indicates living in a comprehensive-SFL state was not associated with a lower risk of reporting asthma symptoms. SHS exposure in public transport was linked to increased risk for wheeze (Adjusted Odds Ratio (AOR) 16.6; 95%confidence interval (CI), 2.69-101.7) and current wheezing (AOR 24.6; 95%CI, 3.53-171.8). Conclusions: Adolescents continue to be exposed to SHS in a range of public venues in both comprehensive- and partial-SFL states. Respiratory symptoms are common among those reporting SHS exposure on public transportation. Non-compliance with SFL appears to be frequent in many venues across Malaysia and enforcement should be given priority in order to reduce exposure.

만성폐쇄성폐질환 환자에서 우울과 불안심리 평가 (Depression and Anxiety in Outpatients with Chronic Obstructive Pulmonary Disease)

  • 류연주;천은미;심윤수;이진화
    • Tuberculosis and Respiratory Diseases
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    • 제62권1호
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    • pp.11-18
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    • 2007
  • 연구배경: 만성폐쇄성폐질환(chronic obstructive pulmonary disease, COPD) 환자군에서 우울증 및 불안장애의 유병률이 높고, 이는 치료경과 및 사망률에도 영향을 주는 것으로 알려져 있다. 저자들은 국내연구가 미비한 COPD환자들의 우울과 불안심리에 대한 평가를 하고자 하였다. 방 법: 2005년 9월부터 2006년 8월까지 이화의료원 호흡기내과에서 외래치료 중인 72명의 COPD환자와 정상 대조군 50명에서 Beck Depression Inventory (BDI)와 State-Trait Anxiety Inventory (STAI)로 설문조사를 시행하였고, 임상기록을 분석하였다. 결 과: 1) 연령과 체질량지수, 혈청 알부민 수치는 환자군과 대조군간의 유의한 차이를 보이지 않았다(p>0.05). 우울심리는 BDI점수가 환자군 16(0-37), 대조군 12(1-30)으로 환자군에서 유의하게 높았고(p=0.001), 21점 이상의 우울집단은 환자군이 36%로 대조군 6%에 비해 많았다(p<0.0001). 환자군에서는 경증군 18%(4/22), 중등증군 30%(6/20), 중증군 52%(13/25), 심한 중증군 60%(3/5)로 중증일수록 빈도가 높았다(p=0.008). 2) 불안심리는 환자군에서 SAI 점수 44(20-67), TAI점수 47(20-66)로 각각 대조군 39(26-65), 44(33-90)보다 유의하게 높았다(p=0.005, p=0.022). 환자군에서 BDI와 STAI점수는 상관관계를 보였고(p<0.001), 우울집단에서 불안점수가 유의하게 높았다. 3) COPD환자군에서 우울집단은 비우울집단보다 체질량지수, 기관지확장제후 $FEV_1$의 예측치가 유의하게 낮았고, 현재 흡연자의 비율과 중증도, STAI점수가 유의하게 높았다(p<0.05). 4) 연령과 성별을 통제한 다변량 로지스틱 회귀분석상 95% 신뢰구간으로 비차비는 체질량지수 0.9(p=0.311), 현재 흡연자 3.2(p=0.051), 중증군이상 3.9로(p=0.027), 중증이상의 중증도가 유일한 우울증 발생의 독립적 위험요인이었다. 결 론: COPD환자군에서 우울증과 불안심리가 흔하게 관찰되며, 체질량지수, 폐기능, 현재 흡연력이 우울관련 요인으로 특히 중증도가 높을수록 우울증과 불안장애의 관리가 필요함을 보여주었다.

간호대학생의 일반적 특성 및 건강행동에 따른 그릿, 건강증진행위 차이 융합 연구 (The Convergence Study of Differences in Nursing College Students' Grit and Heath Promotion Behavior by General Characteristics and Heath Behavior)

  • 허은주
    • 한국융합학회논문지
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    • 제11권12호
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    • pp.57-65
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    • 2020
  • 본 연구는 간호대학생의 일반적 특성 및 건강행동이 그릿과 건강증진행위에 어떠한 차이가 있는지 확인하고 그릿과 건강증진행위의 관계를 규명하고자 하였다. 연구대상은 경남 2개 간호학과 3학년 대상으로 수집된 자료 180부를 SPSS 21 프로그램으로 분석하였다. 연구결과, 그릿의 차이는 성별, 건강관심도, 식사습관, 흡연이 통계적으로 유의한 차이가 있었으며, 건강증진행위의 차이는 건강상태인식, 건강관심도, 식사습관, 음주, 운동이 통계적으로 유의한 차이가 있었다. 그릿과 건강증진행위는 유의한 정(+)의 상관관계가 있으며, 그릿, 식사습관, 운동은 건강증진행위에 유의한 정(+)의 영향을 미치는 요인으로 나타났다. 따라서 간호대학생의 건강증진행위에 영향을 미치는 규칙적인 식사습관, 올바른 운동 및 그릿을 높이기 위한 다각적인 교육전략 수립이 필요할 것으로 사료된다.

전문대학생의 생활습관과 체성분 및 삶의 질과의 관계 (Relationship of life style on body composition and quality of life in college students)

  • 박미성;이용희
    • 디지털융복합연구
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    • 제12권6호
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    • pp.397-405
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    • 2014
  • 본 연구의 목적은 전문대학생의 생활습관을 파악하고 체성분 및 삶의 질과의 관계를 분석하기 위하여 시도되었다. 연구 참여자는 전문대학교에 재학 중인 학생으로 건강에 관심이 있어 건강관련 캠페인에 자발적으로 참여한 60명을 대상으로 실시하였고 수집된 자료는 SPSS 18.0 프로그램을 이용하여 t-test, ANOVA 와 Pearson's correlation coefficients를 이용하여 전산통계 처리하였다. 연구결과 참여자의 평균나이는 22.07세로 20~25세가 85.0%이었고 생활습관과 체성분 분석 결과 운동, 흡연, 음주, 체중에 통계적으로 유의한 차이가 있었다. 또한 참여자의 생활습관과 삶의 질은 통계적으로 유의한 상관관계가 있는 것으로 나타났다. 결론적으로 본 연구는 생활습관, 체성분, 삶의 질을 비교하여 대학생의 생활습관 향상과 삶의 질 향상에 기초 자료를 제공하는데 의미가 있다.

가변펄스 모드에 의한 Myalgia 치료를 위한 저주파 시스템의 설계 및 구현 (Design and embodiment of low frequency system for myalgia treatment by variableness pulse mode)

  • 김휘영
    • 한국컴퓨터산업학회논문지
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    • 제8권1호
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    • pp.23-28
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    • 2007
  • 현대인의 과로, 과음, 흡연으로 인한 근육에 스트레스를 주는 자세가 많다. 한 자세로 오래 앉아 있는 시간이 많으므로 근육통은 근육 류머티즘이나 결합 조직염, 근통증으로, 환부를 누르면 경결이 있고 아프다. 근육자체에는 병적변화가 없고 결합 조직염의 경우는 그 근육 주위에 있는 근육막이나 힘줄 신경초 등의 결합조직에 류머티즘 변화가 나타난다. 전형적인 비관절성 류머티즘이기도 하다. 과격한 운동이나 몸에 익숙지 않은 일을 무리하게 했을 경우에 볼 수 있다. 이로인해 본 연구에서는 설정된 주파수가 변화없이 지속되는 파형과 초음파 자극처리장치의 특성을 모드별 주파수 파형으로 연속모드, 10모드, 25모드, 50모드 등으로 다양하게 환자의 상태라 따라 구현이 가능하였다. 실험을 통해 초음파, 저주파장비에 대한 기초기준을 정할 수 있는 샘플을 확립 나름대로 정리하여 기준을 확립하고자 한다.

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