• The Korean Journal of Pain
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• 제10권1호
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• pp.48-53
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• 1997

Background : Epidural morphine provides excellent postoperative analgesia but is often associated with side effects such as nausea, vomiting and pruritus. It has been reported that mixed agonist-antagonist, nalbuphine can reverse side effects of epidural morphine without compromising analgesia. This study was designed to compare the efficacy of each intravenous dose of nalbuphine for treatment of side effects following epidural morphine. Methods : All patients received continuous infusion(2 ml/hr) of epidural morphine-local anesthetics mixture(morphine 4 mg, 1% mepivacaine 50 ml and 0.25% bupivacaine 50 ml) following a loading dose (morphine 2 mg with 1% mepivacaine 7 ml). Patients requesting treatment for nausea, vomiting and pruritus randomly received intravenous nalbuphine 0.05 mg/kg(Group 1; n=20), 0.1 mg/kg(Group 2; n=20) or 0.15 mg/kg(Group 3; n=20). The severity of nausea, vomiting, pruritus, degree of pain, sedation and vital sign were assessed prior to and 30 min after each dose. Results : The severity of nausea, vomiting and pruritus decreased significantly in all groups(p<0.01). Pain and sedation scores were unchanged in all groups. One patient received nalbuphine 0.15 mg/kg, complained of dizziness, agitation and palpitation. His blood pressure who had increased to 170/100 after first dose. Conclusions : This study suggests that intravenous nalbuphine is good for treatment of side effects following epidural morphine, and the dose of Group 1, 0.05 mg/kg, may be recommended as an optimal dose.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제25권2호
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• pp.82-88
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• 2014

Objectives : The aim of our study was to investigate association of norepinephrine transporter gene (SLC6A2) polymorphism and side effects of osmotic-release oral system methylphenidate (OROS MPH) in children with attention-deficit hyperactivity disorder (ADHD). Methods : We recruited drug naive children with ADHD (N=97). We administered OROS MPH by tolerable dosage. At week 8 of treatment, parents completed the Barkley's side effect rating scale. We analyzed two SLC6A2 single nucleotide polymorphisms (SNPs), rs192303 and rs3785143, with blood of subjects. We compared the frequency and severity of each side effect among SLC6A2 genotypes of 2 SNPs. Results : In the analysis of frequency of each side effect, irritability differed according to rs192303 and rs3785143 genotype. In comparisons of severity, talking less and disinterest differed according to rs192303 genotype. In the case of rs3785143, severities of disinterest and irritability were involved with genotype. Conclusion : Side effects of OROS MPH showed an association with SLC6A2 genotype.

• International Journal of Aeronautical and Space Sciences
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• 제16권2호
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• pp.148-156
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• 2015

A continuous type side jet controller which has four nozzles with thrust control devices was considered. It is deployed to a missile for high maneuverability and fast controllability in the terminal guidance phase. However, it causes more complex aerodynamic jet interactions between the side jet and the supersonic free stream than does the conventional impulse type side jet with a small single thruster. In this paper, a numerical investigation of the jet interference effects for the missile equipped with a continuous type side jet thruster is presented. A three-dimensional flow field was simulated by using a commercial unstructured-based CFD solver. The numerical simulation method was validated through comparison with wind tunnel test results for the single jet. The method of defining jet direction for this type of side jet control to minimize simulation cases was also introduced. Flow fields investigation and jet interaction effects for various flow conditions, jet pressure ratios and defined jet direction conditions were performed. From the numerical simulation for the continuous type side jet, extensive aerodynamic interference data were obtained to construct an aerodynamic coefficients database for precise missile control.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 2009년도 IWAIT
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• pp.381-384
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• 2009

In the Wyner-Ziv coding, compression performance highly depends on the quality of the side information since better quality of side information brings less channel noise and less parity bit. However, as decoder generates side information without any knowledge of the current Wyner-Ziv frame, it doesn't have optimal criterion to decide which block is more advantageous to generate better side information. Hence, in general, fixed block size motion estimation (ME) is performed in generating side information. By the fixed block size ME, the best coding performance cannot be attained since some blocks are better to be motion estimated in different block sizes. Therefore if there is a way to find appropriate ME block of each block, the quality of the side information might be improved. In this paper, we investigate the effects of variable block sizes of ME in generating side information.

• Tribology and Lubricants
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• 제16권1호
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• pp.27-32
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• 2000

This paper describes that the leaf spring damper (LSD) developed by authors can be controled by side clearance between side covers and leaf springs. The test rig and two prototype dampers with different side clearance were manufactured. Experiments were performed to investigate the effects of side clearance on the damping of the leaf spring damper. The stiffness and damping coefficients are obtained from the displacements and the reaction forces generated by rotating the eccentric shaft. All dynamic coefficients are plotted with the excitation frequency which is adjusted by rotating speed of the shaft.

• 대한물리치료과학회지
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• 제18권2호
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• pp.17-28
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• 2011

Purpose: The aim of this study was to ascertain the effects of the lower extremity muscle strengthening exercise on balance and ambulation of children with cerebral palsy. Methods: 10 subjects who participated in this research undertook the 12-week the lower extremity muscle strengthening exercise program, which consisted of a series of mat exercises and sling exercises. The statistical significances were examined by using Wilcoxon signed-rank test, a non-parametric test, for evaluating the improvement of balance and ambulation of the subjects. In order to evaluate the correlation among the variables, Pearson's correlation coefficients were also calculated. In all statistical analyses the significance level was selected as ${\alpha}$=0.05. Results: Berg balance scale(BBS) was significantly increased after the intervention(p<.05). Percentage weight bearing(PWB) was decreased after the intervention, but there was no significant difference. Time up and go test(TUG) value was significantly decreased(p<.05). Gait velocities was increased after the intervention, but there was no significance. Stride length, step lengths of the affected side and the sound side were significantly increased after the intervention(p<.05). In the correlation analyses of the measures before the intervention, TUG had significant negative correlation to BBS and gait velocity(p<.05). Stride length, step lengths of the sound side and the affected side had significant positive correlation between themselves(p<.01). In the correlation analyses of the measures after the intervention, TUG had significant negative correlation to BBS and gait velocity(p<.05). BBS revealed significant positive correlations to stride length, step lengths of the sound side and the affected side(p<.05). Stride length, step lengths of the sound side and the affected side had significant positive correlation between themselves(p<.01). Conclusion: Based upon the outcomes as above, it is likely that the muscle strength exercises have substantial effects on balance and ambulation of children with cerebral palsy. Thus various lower extremity muscle strengthening exercise programs are required to be studied and developed in order to contribute to functional improvements of children with cerebral palsy.

• 혜화의학회지
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• 제5권2호
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• pp.473-484
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• 1997

This study was performed to survey the specific information about the time of onset, frequency, duration, and severity of the side effect of radiation therapy following breast cancer surgery, and identify the difference of these data according to the type of breast cancer surgery : modified radical mastectomy(MRM) vs. breast consevative operation(BCO). 38 breast cancer patients were interviewed with side effect profile about radiation therapy. Interview was done weekley from the start of radiation therapy through 6 weeks and 3 month follow-up interview was done at 3 month after completion of the treatment. The results are as follow : 1. Total score of side effect experienced by the breast cancer patients was rapidly increased at 2-3 week after intiating treatement and continousely raised maintaing high score until completion of the treatement. Some problems like cough, dyspnea and pain were more experienced after treatment. 2. Patients with modified radical mastectomy showed more total score of side effects than patients with breast conservative operation. And both patients with MRM and BCO experienced similar pattern of side effect to radiation therapy. Through these data we concluded that side effect to radiation therapy was not ended at completion of treatement. Patents will continously experiend various problems and suffer from not only acute side effects like skin problem, sore throat and swollowing difficulty but also late effect of the radiation therapy. Clinically these data can be used for oncologic nurse to provide informational interventions to prepare breast cancer patients for the radiation therapy.

• PNF and Movement
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• 제13권4호
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• pp.181-188
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• 2015

Purpose: This study aimed to examine the effects of proprioceptive neuromuscular facilitation (PNF) lower extremity patterns combined with elastic bands applied to stroke patients diagnosed with hemiplegia through self-training using the non-paralyzed side approach and the paralyzed side approach, and to investigate the differences in the effects. Methods: Nine chronic stroke patients who were being treated not more than twice a week at H, K, R, and C hospitals located in Gangwon-do, performed self-training for 16 minutes, two times per day for four weeks between August and October 2015. The subjects' balance ability was measured using the Tetrax stability index, the weight distribution index, the Berg Balance Scale (BBS), and the Timed Up and Go (TUG) test before the experiment and four weeks later. Among the statistical methods, paired t-tests were conducted for intra-group comparison of the measurements taken before and after the experiment, and independent t-tests were conducted for inter-group comparison of the ex post facto values. The statistical significance level was set to 0.05. Results: When the lower extremity patterns were applied to the non-paralyzed side group and the paralyzed side group, significant intra-group differences were observed for the Tetrax stability index, the weight distribution index, the Berg Balance Scale (BBS), and Timed Up and Go (TUG) tests (p<0.05); however, the inter-group comparisons showed no significant differences. Conclusion: The non-paralyzed side approach was found to be easy for patients to participate in and it also affected the patients' paralyzed side. Although the paralyzed side approach produced good exercise effects in a short period of time, it could result in adverse effects, such as a decrease in motivation and self-confidence. Therefore, these approaches are considered to be more effective when they are selectively applied depending on the purpose of the intervention and the degree of a patients' participation.

• 한국항만학회지
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• 제13권2호
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• pp.409-418
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• 1999

Gamcheon Bay has complicated and unique flow pattern which is affected by topography characteristics of a semi-closed bay and warm water discharge from the power plant located at the bay. It is very important to consider warm water discharge with tidal period and wind effects, which are mainly acting on the surface flow patterns in Gamcheon Bay. The results of observation show as follows; i) Because Gamcheon bay has much elongated shape to the north-south direction and narrow entrance with two separated breakwaters, the flow is very weak inside the bay. ii) The main flow path is at the west side of the bay. The direction of flood current is northward along the west side of the bay and the direction of ebb current is southward along the west side of the bay. The southward direction of warm water discharge has curved to the west side of the bay. iii)At the period of flood current for neap tide, the flow direction is southward in the bay, which is thought by the effects of warm water discharge. But at the bottom layer, the effects of tidal current reached to the middle of the bay, and showed features like eddy. iv) The wind effect is very strong, especially, prominent in the west and east side of the bay.

• Wind and Structures
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• 제21권2호
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• pp.183-202
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• 2015

Experiments on two-dimensional rectangular prisms with various side ratios (B/D=2, 3, and 4, where B is the along-wind dimension, and D is the across-wind dimension) and rounded corners (R/D=0%, 5%, 10%, and 15%, where R is the corner radius) are reported in this study. The tests were conducted in low-turbulence uniform flow to measure the wind pressures on the surfaces of 12 models for Reynolds numbers ranging from $1.1{\times}10^5$ to $6.8{\times}10^5$. The aerodynamic force coefficients were obtained by integrating the wind pressure coefficients around the model surface. Experimental results of wind pressure distributions, aerodynamic force coefficients, and Strouhal numbers are presented for the 12 models. The mechanisms of the Reynolds number effects are revealed by analyzing the variations of wind pressure distributions. The sensitivity of aerodynamic behavior to the Reynolds number increases with increasing side ratio or rounded corner ratio for rectangular prisms. In addition, the variations of the mean pressure distributions and the pressure correlations on the side surfaces of rectangular prisms with the rounded corner ratio are analyzed at $Re=3.4{\times}10^5$.