• Radiation Oncology Journal
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• 제38권2호
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• pp.84-92
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• 2020

Patients undergoing radiation therapy for head and neck cancer (HNC) experience significant early and long-term side effects. The likelihood and severity of complications depends on a number of factors, including the total dose of radiation delivered, over what time it was delivered and what parts of the head and neck received radiation. Late side effects include: permanent loss of saliva; osteoradionecrosis; radiation recall myositis, pharyngoesophageal stenosis; dental caries; oral cavity necrosis; fibrosis; impaired wound healing; skin changes and skin cancer; lymphedema; hypothyroidism, hyperparathyroidism, lightheadedness, dizziness and headaches; secondary cancer; and eye, ear, neurological and neck structures damage. Patients who undergo radiotherapy for nasopharyngeal carcinoma tend to suffer from chronic sinusitis. These side effects present difficult challenges to the patients and their caregivers and require life-long strategies to alleviate their deleterious effect on basic life functions and on the quality of life. This review presents these side effects and their management.

• 대한약침학회지
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• 제4권2호
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• pp.65-71
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• 2001

Objectives : This study was performed to examine the patterns and to prevent the side effects of CF Herbal Acupuncture treatment Methods : We observed 10 patients who complained the side effects of Herbal acupuncture CF and 2 healthy men for the sake of examine the cause from the August 17 to 24, 2001. Results 1. All of the patients complained severe pain, redish, and edema on the side of injections 2. We were able to witness decrease in pain, redish, and edema, after 2days of injection. After 4days, we were unable to any side effects. 3. According to the clinical studies, we came to determine that the CF herbal abstract which caused the side effects were manufactured between 4 to 13 days, August 4. We assume these side effects were caused by minute quantity of toxin remaining in the screw pressor mixed with the CF herbal abstract.

• 한국임상수의학회지
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• 제39권1호
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• pp.9-15
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• 2022

As more veterinary clinics become specialized with the growth of the companion animal market, an increasing number of veterinary clinics perform orthopedic surgery and use orthopedic products, some of which are defective and have side effects. Thus, the present study aimed to prepare fundamental data for the revision and development of manufacturing standards for these products in order to prevent their side effects. We conducted a survey targeting veterinary clinics as consumers and medical device companies as suppliers. Veterinary clinics were surveyed via offline and online methods; 320 clinics that offered orthopedic surgery and approximately 4,000 veterinary clinics that were registered in the Korean Veterinary Medical Association were targeted, and 153 veterinary clinics responded to the survey. The survey for medical device companies, was performed online, targeting 29 companies; 14 companies responded. The number of side effects of orthopedic products was higher in animal orthopedic products than in those for human use. Many consumers tended to suspect that side effects were caused by product defects. To resolve side effects after using orthopedic products, consumers mostly underwent reoperation. Meanwhile, some severe cases proceeded to legal disputes. Similarly, medical device companies, or the suppliers, responded that most side effects occurred in veterinary orthopedic products and that product defects and mistakes in use were the causes. As for most of the follow-up actions for side effects, these companies either reported the issue to those in charge or analyzed and resolved the issues themselves. Therefore, to develop quality products, suppliers should be provided with clear standards for the production, and information disclosure and a report system for side effects should be particularly established to gain consumers' trust regarding the safety of these products.

• 대한한방내과학회지
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• 제39권4호
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• pp.686-698
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• 2018

Objectives: The aim of this study was to report the current status of the Korean traditional medicine side effects described in domestic western medical journals in the past 10 years. Methods: We searched for domestic western medical papers about Korean traditional medicine side effects cases from January 1, 2008, to August 31, 2017. Results: Thirty papers were selected from 31 studies. The number of papers of side effects caused by acupuncture was 21 (70%), by herbal medication was 7 (23%) and by thread lifting was 2 (7%). The number of papers of side effects caused by Korean medical doctors was 20 (66.8%), by non-medical persons including patients was 2 (6.6%), by herbal pharmacists was 1 (3.3%), by multiple practitioners, including Korean medical doctors, was 1 (3.3%), and by unknown persons was 6 (20%). Reported side effects were mostly mild, except for death and severe side effects. Conclusions: Studies of Korean traditional medicine side effects are short, and in-depth studies of stability are needed. These studies will improve the safety of the Korean traditional medicine.

• 생물정신의학
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• 제5권2호
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• pp.166-174
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• 1998

항정신병약물에 의한 부작용의 치료전략은 예방이 최우선이며, 그 다음이 조기발견 및 이에 대한 적절한 치료이다. 항정신병약물의 부작용을 강조하는 이유는, 약물에 대한 부정적 인상을 강화시키려는 데 있지 않고, 약물의 치료적 효과를 극대화시키려는 데 있다. 이를 위해서는 약물의 속성과 환자의 특징을 고려한 약물의 선택과 사용뿐만 아니라, 부작용에 대한 면밀한 이해와 이에 대한 치료전략을 숙지해야 한다.

• Journal of Korean Neurosurgical Society
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• 제62권4호
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• pp.487-491
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• 2019

Conservative therapy with appropriate antibiotics is essential for most patients with infectious spondylitis. Although most antibiotics do not cause problems if it used properly and serious side effects are rare, side effects can occur with any class of drugs and adverse reactions of antibiotics can range from mild allergic reactions to serious and fulminant adverse events. These side effects are also extremely variable from patient to patient and from antibiotic to antibiotic. A side effect of antibiotics may paradoxically increase inflammatory marker levels. Here, the author presents two cases of antibiotic-induced increase in inflammatory markers in cured infectious spondylitis. The patients were successfully treated after stopping the antibiotic therapy. The differential diagnosis between antibiotic side effects and infection should be considered very carefully because the treatment is completely different. Although the exact mechanisms underlying successful treatment without antibiotics are unclear, we should consider the side effects of antibiotics when following inflammatory markers during treatment of infectious spondylitis.

• 동의신경정신과학회지
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• 제11권1호
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• pp.97-102
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• 2000

In the study of psychosomatic disorders caused by Qi-experience, the results were as follows: 1. People are becoming more and more interested in qigong, but sometimes peple are suffer from side effects from Qi-experience. In oder to treat this side effects of qigong, it is important to control Qi unbalance. And this is associated with the mechanism of stress-reaction. 2. The causes of side-effects were tension of body and mind, concentration of head, enduring breath, and wrong qigong-method, etc. 3. The symptoms of side-effects were headache, flushing face, chest discomfort, neck stiffness, indigestion, etc. 4. The theraphy of side-effects is herb-medicine, acupuncture, moxibution, and more effective by application of psychotheraphy, relaxation-theraphy, music, aroma, taping.

• 대한한방소아과학회지
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• 제24권3호
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• pp.33-42
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• 2010

Objectives: The purpose of this study is to investigate the frequency of side effects, and the range of the side effects from Korean herb medicine on children. Methods: The study has been carried out from 212 children who took Korean herb medicine in Department of Pediatrics, $\bigcirc\;\bigcirc$ Oriental Medical Hospital from September 2009 to February 2010. The study was completed through patients chart review and telephone survey. Results: 1. There were 6 side effect cases on male, and 3 side effect cases on female out of 212 children. The incidence of side effect was 4.2%. 2. The most common side effect was abdominal pain. The most common related organ was digestive organ. 3. The side effect occurred within one to three days after taking Korean herb medicine, and the symptoms were mostly disappeared after taking the Korean herb medicine into divided dose or less dose. Conclusions: The symptom of side effects on children was not as severe as other adverse drug reactions often seen in Western medication. The most common symptom was abdominal pain. Further studies are needed.

• Korean Journal of Acupuncture
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• 제22권3호
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• pp.165-174
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• 2005

Objective : The objective of this study is to investigate the inhibitor effects of an traditional oriental herb, Sophora flavescens on the hepatic and renal side effects of chemotherapy by using B16-BL6 melanoma-injected C57BL6 mouse tumor model. Methods : In this study, the effects of an traditional oriental herb, Sophora flavescens, on the side effects of chemotherapy were studied using B16 melanoma-injected C57BL6 mouse tumor model. Results : Sophora flavescen has significant effect on the reduction of the side effects of chemotherapy. Sophora flavescen recovered the reduction of WBC and RBC during cisplatin chemotherapy. Water extract of Sophora flavescens significantly inhibited cisplatin-induced increase of serum blood urea nitrogen (BUN) which is a good indicator of renal toxicity. Sophora flavescens extract does not decrease the anti-tumor activity of cisplatin showing that it can selectively inhibit side effects of anticancer drugs preserving beneficial effort. Conclusion : Theses results suggest a possibility that Sophora flavescens extract can be used for cancer patients for the reduction of the side effects and improving the quality of life during chemotherapy of cancer patients.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 1998년도 춘계학술대회논문집
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• pp.53-57
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• 1998

In order to investigate the effects of the variables during the stamping process upon the side wall curl behavior, experiments and finite element analyses were done using a 90 degree draw-bending test. The variables considered were the die radius, the forming speed, the restraint force, the lubrication and the sheet grade. The experiments and simulation conditions were selected according to the design of experiment (DOE) approach. The effects of the restraint force, the lubrication and the forming speed were the same for both high strength and mild steels, but the effects of the die radius on the side wall curl were dependent on the magnitude of the die radius and the sheet grade. A straight side wall was observed for both high strength and mild steels when the die radius was about 2∼3 times of the sheet thickness. It was recommended that the restraint force, the forming speed and the friction be increased in order to reduce the side wall curl.