• Journal of the Korean Society of Radiology
• /
• v.17 no.5
• /
• pp.791-800
• /
• 2023

This study was conducted to lay the foundation for creating a society safe from radiation by investigating the establishment of a radiation social safety net and the establishment of safety awareness and safety culture among citizens living in Busan. Data was collected through an online survey, and 200 copies of the survey were analyzed. Data were analyzed using SPSS Window Ver 28.0. To verify differences between groups, t-test and one way ANOVA were performed, and correlation analysis was performed to confirm the relationship between variables. In addition, multiple linear regression analysis was conducted to confirm the influence between variables. As a result, first, in terms of building a social safety net, citizens' safety awareness, and establishing a safety culture, the scores of the group with male gender, age in 20s, and high school graduation were found to be high. Among them, there was a statistical difference in gender at the significance level of .01 for building a social safety network and at the significance level of .05 for establishing a safety culture. In terms of occupation, there was a statistical difference between professionals and service workers at the significance level of .05 regarding the building of a radiation social safety network. Second, as a result of multiple regression analysis, it was found that 'local government radiation safety education', a subordinate factor in building a radiation social safety network, had a positive effect on citizens' safety awareness and establishment of a safety culture. Third, the results of the correlation analysis between the building of a social safety network, citizens' safety awareness, and establishment of a safety culture showed a positive correlation. Therefore, it is believed that a good radiation social safety network will have a positive impact on citizens' safety awareness and the establishment of a safety culture.

• Journal of Chest Surgery
• /
• v.47 no.4
• /
• pp.367-372
• /
• 2014

Background: We compared the mid-term results of the Cox maze IV procedure using argon-based cryoablation with a procedure using $N_2O$-based cryoablation. Methods: From May 2006 to June 2012, 138 patients (mean age, $58.2{\pm}11.0$ years) underwent the Cox maze IV procedure. Eighty-five patients underwent the maze procedure using an $N_2O$-based cryoprobe (group N), and 53 patients underwent the maze procedure using an argon-based cryoprobe (group A). Bipolar radiofrequency ablation was concomitantly used in 131 patients. The presence of atrial fibrillation immediately, 6 months, 1 year, and 2 years after surgery was compared. Results: Early mortality occurred in 6 patients (4.3%). There were no differences in early mortality or postoperative complications between the two groups. Nineteen of 115 patients (16.5%) remained in atrial fibrillation at postoperative 12 months (14 of 80 patients (17.5%) in group N and 5 of 35 patients (14.3%) in group A, p=0.669). There were no differences in the number of patients who remained in atrial fibrillation at any of the time periods except in the immediate postoperative period. A multivariable analysis revealed that the energy source of cryoablation was not associated with the presence of atrial fibrillation at 1 year (p=0.862) and that a fine F wave (<0.1 mV) was the only risk factor predicting the presence of atrial fibrillation at 1 year (p<0.001, odds ratio=20.287). Conclusion: The Cox maze IV procedure using an argon-based cryoprobe was safe and effective compared with the maze procedure using an $N_2O$-based cryoprobe in terms of operative outcomes and the restoration of sinus rhythm for up to 2 years after surgery.

• Journal of Korean Society of Transportation
• /
• v.32 no.3
• /
• pp.207-217
• /
• 2014

Many a number of policies have been tried to reduce auto accidents so far, but it is obvious that further studies are still needed to find a more fundamental and multi-dimensional preventive measure with effect. The National Mental Health Statistics shows that the most profound forms of negative emotions, that is, depression and anxiety, have been increasing, but studies on such a topic are scarce to find. Therefore, we conducted a structural analysis between the negative emotions, including depression and anxiety, of drivers and their driving behaviors using a Structural Equation Modeling(SEM) technique. The review of past literature and studies indicated that not all of human emotions manifest themselves as the ultimate behaviors because they go through emotion regulation Strategies. For this reason, the purpose of this study was set to analyze the structural model developed in this study reflecting the emotion regulation strategies. The result of our analysis showed that the driver's negative emotion had a more significant influence on dangerous driving behaviors than safe ones, and especially, the expressive suppression strategy was found to be the highest factor. Also, the total effect analysis with the negative emotional factors showed that expressive suppression had more significant influence compared to that of cognitive reappraisal. The implication of this study might provide a better understanding on driving behaviors of the drivers and could be used as a fundamental study for future policy development to reduce traffic accidents.

• The Korean Journal of Franchise Management
• /
• v.5 no.1
• /
• pp.143-160
• /
• 2014

This study focuses that the business starters can refer to this study, select better franchise headquarter and make the franchise member agreement. The most concerned part for the people who want to open franchise shop is what brand is reliable and safe to them. I have analyzed disclosure report that contains overall information of franchise headquarters and researched 300 franchise shops as sample. I drew the conclusion of the decision factors of franchise member agreement, overlooked demographical status by frequency analysis with SPSS 18.0 and performed disperse analysis to examine the decision factors of franchise member agreement and the difference between sex, service type, shop size and income level. In conclusion, the most concerned factor for the franchise agreement is sales management. Sex, shop size and income level are not meaningful factors, but the cost and training management factors are considered differently based on the service type. I hope 1) this study can be utilized for the franchise business starters judge and refer information level provided by the headquarters and make a successful franchise shop business. 2) this study can make solid relationship between franchise members and present a long term vision to them. Finally, this study can be a foundation to promote franchise field through making and supplementing the law of promoting proficient and good franchise headquarters and fairness of franchise transaction and franchise encouragement.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.22 no.5
• /
• pp.182-199
• /
• 2023

Since 2021, government departments have been promoting Automated Driving Technology Development and Innovation Project as national research and development(R&D) project. The automated vehicles and service technologies developed as part of these projects are planned to be subsequently provided to the public at the selected Living Lab City. Therefore, it is important to determine a spatial area and operation section that enables safe and stable automated driving, depending on the purpose and characteristics of the target service. In this study, the static Operational Design Domain(ODD) elements for Level 4 automated driving services were reclassified by reviewing previously published papers and related literature surveys and investigating field data. Spatial analysis techniques were used to consider the reclassified ODD elements for level 4 in the real area of level 3 automated driving services because it is important to reflect the spatial factors affecting safety related to real automated driving technologies and services. Consequently, a total of six driving mode changes(disengagement) were derived through spatial information analysis techniques, and the factors affecting the safety of automated driving were crosswalk, traffic light, intersection, bicycle road, pocket lane, caution sign, and median strip. This spatial factor analysis method is expected to be useful for determining special areas for the automated driving service.

• Journal of Microbiology
• /
• v.44 no.5
• /
• pp.548-555
• /
• 2006

FaeG is the key factor in the infection process of K88ad enterotoxigenic Escherichia coli (ETEC) fimbrial adhesin. In an attempt to determine the possibility of expressing recombinant FaeG with immunogenicity for a new safe and high-production vaccine in E. coli, we constructed the recombinant strain, BL21 (DE3+K88), which harbors an expression vector with a DNA fragment of faeG, without a signal peptide. Results of 15% SDS-polyacrylamide slab gel analysis showed that FaeG can be stably over-expressed in BL21 (DE3+K88) as inclusion bodies without FaeE. Immunoglobulin G (IgG) and M (IgM) responses in pregnant pigs, with boost injections of the purified recombinant FaeG, were detected 4 weeks later in the sera and colostrum. An in vitro villius-adhesion assay verified that the elicited antibodies in the sera of vaccinated pigs were capable of preventing the adhesion of K88ad ETEC to porcine intestinal receptors. The protective effect on the mortality rates of suckling piglets born to vaccinated mothers was also observed one week after oral challenge with the virulent ETEC strain, $C_{83907}$ (K88ad, $CT^+,\;ST^+$). The results of this study proved that the adhesin of proteinaceous bacterial fimbriae or pili could be overexpressed in engineered E. coli strains, with protective immune responses to the pathogen.

• Korean Journal of Clinical Pharmacy
• /
• v.30 no.1
• /
• pp.1-10
• /
• 2020

Objective: The aim of the study was to perform a meta-analysis of randomized clinical trials to compare the clinical efficacy and safety between combination of cyclin-dependent kinase (CDK) 4/6 inhibitors with aromatase inhibitors (AIs) and AIs alone in patients with hormone receptor+/human epidermal growth factor receptor type2-(HR+/HER2-) advanced breast cancer. Methods: Published clinical studies were identified through electronic database searches until February 2019. Literature qualities were assessed by the Scottish Intercollegiate Guidelines Network Checklist. Key endpoints of efficacy were progression-free survival (PFS), objective response rate (ORR), and clinical benefit (CB). Endpoints of safety were adverse events (AEs) (neutropenia, leukopenia, any grade 3/4 AEs, and serious AEs) and on-treatment death. Meta-analysis was performed using the RevMan 5.3 software. Results: The selected five studies were evaluated as "good" in quality assessment. Compared to AIs alone, the combination therapy significantly improved PFS (pooled hazard ratio=0.55; 95% confidence interval (CI) 0.49-0.62), ORR (odds ratio=1.78; 95% CI=1.49-2.13), and CB (odds ratio=1.86; 95% CI=1.51-2.28). The prevalence of AEs was significantly higher in the combination group than in the AIs alone group. On-treatment death was greater in the combination group than in the AIs alone group, although insignificant. Conclusion: The combination therapy of CDK4/6 inhibitors with AIs was more effective for the treatment of HR+/HER2- advanced breast cancer, but less safe than AIs alone. The combination therapy should be effectively managed through patient monitoring, and further studies are needed to reduce AEs in the combination therapy of CDK4/6 inhibitors with AIs.

• Journal of Food Hygiene and Safety
• /
• v.16 no.2
• /
• pp.103-110
• /
• 2001

Predictive food microbiology(PFM) is an emerging area of food microbiology since the later 1980’s. It does apply mathematical models to predict the responses of microorganism to specified environmental variables. Although, at present, PFM models do not completely developed, models can provide very useful information for microbiological responses in HACCP(Hazard Analysis Critical Control Point) system and Risk Assessment. This study illustrates the possible use of PFM models(PMP: Pathogen Modeling Program win5.1) with milk in several elements in the HACCP system, such as conduction of hazard analysis and determination of CCP(Critical Control Points) and CL(Critical Limits). The factors likely to affect the growth of the pathogens in milk involved storage fixed factors were pH 6.7, Aw 0.993 and NaCl 1.3%. PMPwin5.1 calculated generation time, lag phase duration, time to level of infective dose for pathogens across a range of storage (Critical Control Points) and CL(Critical Limits). The factors likely to affect the growth of the pathogens in milk involved storage temperature, pH, Aw and NaCl content. The factors likely to affect the growth of the pathogens in milk involved storage temperature, pH, Aw and NaCl content. The variable factor was storage temperature at the range of 4~15$^{\circ}C$ and the fixed factors were pH 6.7, Aw 0.993 and NaC 1.3%. PMPwin5.1 calculated generation time, lag phase duration, time to level of infective dose for pathogens across a range of storage temperature.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.7
• /
• pp.573-584
• /
• 2016

The train control system is a facility to ensure model-based design and safe train operation, and its safety is the most important factor for system introduction, complexity of the design information and traceability etc. Therefore, the model-based design and safety activities regarding the way-side equipment of a train control system is also highlighted. To solve this problem, In this paper, model-based design was carried out first to develop an effective train control system, which is represented by SysML(System Modeling Language). The test scenarios that can take advantage of the design model were created to improve the train safety control system. Case studies of a model-based design of a train-centric train control system were applied to the test scenarios; the results demonstrated its usability. The improved activity over the test highlighted the safety improvement approach, and it is expected to reduce the cost and time in the conceptual design of a future development model-based train control system.

• Journal of Advanced Marine Engineering and Technology
• /
• v.37 no.8
• /
• pp.962-968
• /
• 2013

Problem of greenhouse gases associated with global warming and the world rise in fuel oil prices due to the depletion of fossil fuel has attracted attention. For this reason, maritime transport business, has shown interest in green-ship technology to reduce the consumption of fuel and reduce greenhouse gas for environmental protection. Power system of the ship is one of the most important factors for safe operation. Therefore, at design of ship power system, most of existing vessel used comparative large capacity generator in order to respond peak load such as bow thruster, crane and etc. In the navigation of ship, marine generators most would be operated at low load operation. In the low load operation of the generation rate of 50% or less, the operation efficiency of the generator it deteriorated, to consume more fuel oil. It also, it means that adversely effect the life of the generator. In this paper, studied how to apply for a secondary battery in container ship that relatively frequent arrival and departure in port. As a result, in order to apply the secondary battery to increase the operating efficiency of the generator during the voyage, it was confirmed that it is possible to reduce fuel consumption.