• 사상체질의학회지
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• 제20권3호
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• pp.164-175
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• 2008

1. Objective The purpose of this study is to investigate the anti-aging and anti-oxidant effects of Bopyewon-tang(BPW) in Liver and Lung cell. 2. Methods This experiment was used the tissue of liver and lung cells of 6, 52 and 68 weeks old SD rats. Each age group was again divided into three groups. One group, as normal group, was not-treated cells, another group, as control group, was saline-treated cells, and the last group, as experimental group, was BPW -treated cells. After culture for 48 hours, each groups measured the level of SOD, GSH, MDA and NO in the tissue of liver and lung cells. 3. Results and Conclusion 1. The activity of SOD in liver of in 52 w-BPW group, 68 w-BPW group, and in lung of 68 w-BPW were significantly increased in comparison with those of the normal groups. 2. The levels of NO in liver of in 68 w-BPW group was significantly decreased in comparison with those of the normal groups. 3. The levels of MDA in lung of in 68 w-BPW group was significantly decreased in comparison with those of the normal groups.

• 대한한방내과학회지
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• 제25권4호
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• pp.147-157
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• 2004

Objectives : This experiment was done to evaluate the effects of Hyuntogobon-hwan(HTG) on antioxidant capability and lipidic concentration in blood, both of which are presumed to be related to aging. Methods : 12 week-old SD rats were divided into controlled group, uncontrolled group and HTG group. As controlled and HTG groups were given subcutaneous injection of D-galactose(50mg/kg/rat), at the same time HTG group was administered extract of Hyuntogobon-hwan(270mg/200g). HTG injections continued for 6 weeks. After initial injections, blood was drawn from each group and the following were measured: the activity of SOD, GSH-px, catalase in erythrocytes, TSARS value, concentration of total lipid, tryglyceride in blood plasma. Results : The activities of SOD and GSH-px in erythrocytes increased significantly in HTG group compared with controlled group. The activity of catalase seemed to increase slightly, but it was barely noticeable. The concentration of total lipid in plasma decreased significantly in HTG group compared with controlled group. The value of TBARS in plasma seemed to decrease slightly, but it was barely noticeable. Conclusions : According to the above results, Hyuntogobon-hwan has an influence on aging by virtue of activation of antioxidative enzyme systems in erythrocytes and concentrations of lipid in blood plasma.

• 한국노년학
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• 제28권4호
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• pp.925-940
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• 2008

현대 사회에서 노인 인구의 비율이 꾸준하게 증가하면서, 정상적 및 병리적 노화와 관련된 기억 결함을 다루는 인지적 재활 전략의 영향력도 차차 커지고 있다. 본 논문에서는 현재 이루어지고 있는 노인을 위한 기억 재활 기법을 개관하였다. 먼저, 기억의 노화를 이해하기 위한 이해의 틀로서 인간의 기억 체계를 고찰하였고, 정상적 노화와 알츠하이머병과 같은 병리적 노화에 따른 기억 수행에 관하여 이루어진 연구결과들을 개관한 다음, 그 효과가 입증된 기억 재활 기법들을 소개하였다. 현재까지의 기억 재활 기법들은 아직 남아있는 외현 기억 촉진, 상대적으로 손상되지 않은 암묵 기억 이용, 외부 기억보조 도구 사용에 초점을 맞춘 것이었으나, 새로운 접근으로 뇌 가소성에 기반을 둔 기억 훈련 방법의 가능성을 제안하였다.

• 패션비즈니스
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• 제14권4호
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• pp.132-145
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• 2010

These days, the aging population is becoming a critical social issue; the activation of the silver industry for the Y-O generation, meaning the young-old group of aged 55-64, is accelerating now. Pants are very important item to this generation, since they pursue active life with an exercise and leisure activities. Therefore, the physical, psychological, and social characters as well as the changed life style of women in the Y-O generation were reviewed, based on former studies and books. The consumer's patterns and actual wearing conditions about slacks were researched and analyzed through the survey toward 300 women aged 55-65 living in Seoul. Based on this research, information was provided for the development of slacks pattern which is suitable to the deformed body and aesthetic consciousness of the Y-O generation.

• 한국가정과교육학회지
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• 제23권3호
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• pp.161-183
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• 2011

본 연구는 변화하는 고령화사회에 대응하고 노인문제에 대비하기 위하여 교육적 차원에서 고등학생들이 자신의 노후를 준비할 수 있도록 '성공적인 노후생활 준비교육'을 위한 가정과 수업을 설계하고 개발하는데 그 목적이 있다. 이를 위해 실천적 문제 중심 교수 학습 과정안을 개발하였다. 2007년 개정 교육과정과 해설서를 분석하여 실천적 문제를 설정하고, 2007년 개정 교육과정과 제 7차 교육과정의 기술 가정, 가정과학, 인간발달 교과서, 청소년 대상 노인교육에 관한 선행연구의 내용 요소를 분석하여 5개의 공통 주제를 선정하였으며, 이를 바탕으로 수업의 최종목표를 설정하였다. 실천적 문제는 '노후에 성공적이고 자립적인 생활을 하기 위해 우리는 무엇을 해야 하는가?이고, 주제는 고령화사회와 인구변화, 노인의 특성, 노후준비, 노인돌보기, 노인복지서비스이며, 선정된 5개의 주제는 다시 고령화사회와 노인에 대한 이해, 노후에 대한 개인 가족 사회의 준비 영역으로 나누어 재구성하였다. 수업의 최종 목표는 '고령화사회와 노인의 특성을 이해하고 자신의 행복한 노년의 삶을 준비하기 위해 현재 노인 문제가 발생한 배경을 비판적으로 추론하여 원인을 규명하고, 성공적이고 자립적인 노후를 준비할 수 있는 대안을 합리적으로 모색하며, 대안의 파급효과를 추론하여 가장 최선의 방법을 선택할 수 있는 문제해결능력을 기를 수 있다'로 설정하였다. 실천적 문제 중심 교수 학습 과정안은 총 5차시의 실천적 추론 수업으로 개발되었다. 이에 따라 실천적 문제 중심 '노후생활 준비교육'의 후속 연구로서, 고등학생의 노후준비교육을 일반화 할 수 있도록 보다 많은 학교 현장에서 정규 교과목 수업에 적용하여 그 효과를 검증하는 연구가 실시되기를 바라며, 실천적 추론 수업과 강의식 수업과의 비교 연구가 이루어져 실천적 추론 수업의 효과를 검증할 수 있는 후속연구가 필요함을 제언하였다.

• 농촌지도와개발
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• 제17권4호
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• pp.773-797
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• 2010

Recent years, being advanced the phenomena of fewness and aging rapidly in rural areas, rural community has been collapsed fastly. This study is aimed for two intentions: the one is identification of the actual conditions of rural diminishing in population, and the other is having a view of real picture of it in future. The major result of this study is summarized as follows. First, as a result of the rural area's shrinking for a long time advanced, the rural community has grown to under the minimum autogenesis level. Futher more this study have a look out in ten years later that rural community will diminish in population to 42% size compared with now, and the number of elder than 80 years old occupy a half of total population in a standard case. Such a consequence of this study implies no doubt that the rural development policy must lay a stress to cope with a serious situation of rural scantiness. And policy conversion calls for having a new understanding of this situation first.

• 말소리와 음성과학
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• 제6권2호
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• pp.81-88
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• 2014

The normal aging process on speech production and these changes are perceived by listeners. This study examined whether age perception changed under various conditions of prosodic manipulations in normal listeners, comparing the prosodic changes according to age and sex in adulthood. The older and younger voices were resynthesized by manipulation of the speaking rate and pitch to shift the perceived age of the groups toward each other. Two-way repeated ANOVA were conducted to determine if the prosodic type of resynthesized cue resulted in a significant shift in perceived age of young and old voices. The manipulation of the speaking rate resulted in a significant shift in perceived age for the older and younger groups. A significant shift in age estimates was not observed for the younger male group when pitch was manipulated. There were significant gender-by-age group interactions for prosodic manipulation type. Age-related changes in the prosodic properties of speech may ultimately influence speech perception.

• 대한한방부인과학회지
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• 제20권4호
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• pp.217-224
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• 2007

Purpose: The purpose of this study is to report the effect of oriental treatments for the postpartum disease caused by abortion in an elderly gravida. Methods: The patient in this case, 40 years-old female was admitted at You-Min oriental medicine hospital for 26days($3rd/Jan/2007{\sim}29th/Jan/2007$) due to postpartum disease caused by abortion. Her chief complains were chilling, vertigo, nausea, whole body pain, and sweating. This patient was treated with oriental treatment such as herb medication, acupuncture and moxibustion therapy. Results: After the oriental medical treatment, the patient was improved in the clinical symptom of postpartum disease caused by abortion and the aging process. Conclusion: This case study shows that the postpartum disease caused by abortion in an elderly gravida would be treated more carefully in oriental medicine considering women#s aging.

• The Korean Journal of Physiology and Pharmacology
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• 제19권3호
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• pp.269-274
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• 2015

Chronic inflammation has been proposed as one of the main molecular mechanisms of aging and age-related diseases. Although evidence in humans is limited, short-term calorie restriction (CR) has been shown to have anti-inflammatory effects in aged experimental animals. We reported on the long-term treatment of daumone, a synthetic pheromone secreted by Caenorhabditis elegans in an energy deficient environment, extends the life-span and attenuates liver injury in aged mice. The present study examined whether late onset short-term treatment of daumone exerts anti-inflammatory effects in the livers of aged mice. Daumone was administered orally at doses of 2 or 20 mg/kg/day for 5 weeks to 24-month-old male C57BL/6J mice. Increased liver macrophage infiltration and gene expression of proinflammatory cytokines in aged mice were significantly attenuated by daumone treatment, suggesting that short-term oral administration of daumone may have hepatoprotective effects. Daumone also dose-dependently suppressed tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$ )-induced nuclear factor-${\kappa}B$ (NF-${\kappa}B$) phosphorylation in HepG2 cells. The present data demonstrated that short-term treatment of daumone has anti-inflammatory effects in aged mouse livers possibly through suppression of NF-${\kappa}B$ signaling and suggest that daumone may become a lead compound targeting aging and age-associated diseases.

• 한국약용작물학회지
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• 제20권3호
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• pp.195-201
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• 2012

The management and the use of major mineral nutriments such as nitrogen, phosphorous, and potassium, etc have been practiced and improved in various cultivating methods of Panax ginseng C. A. Meyer. The purposes of this study were to examine the content of major mineral nutrients on different ginseng aging from 1 to 6 years old, to analyze their uptake and utilization in tissues of ginseng, and to find out their proper managing techniques throughout the cultivation of ginseng. In case of the leaves, the N content was not clearly different from 1 to 6 years old, while the content of P and K was generally decreased throughout the cultivating years. In case of the roots, the content of N and K was gradually decreased from 1 to 6 years old, while the P content was increased until 3 years old, decreased at 4 years old, increased again at 5 years old, and decreased again at 6 years old. The uptake amount of N was increased in root of ginseng from 1 to 6 years old, 0.02 to 2.79kg/10a based on dry weight, respectively. Other minerals of P, K, Ca, and Mg were increased for the cultivating year. Comparing the uptake amounts of N, P, K with different cultivating year, they were the highest uptake amount at 4 years old and then were decreased. The management techniques of major mineral in cultivation of ginseng would be studied and evaluated more in order to have better ginseng production.