• 보건행정학회지
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• 제23권4호
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• pp.376-386
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• 2013

Purpose: The purpose of study is to estimate the number of chronic disease patients and medical care expenditure at the time baby-boomers belong to 65 years old aging population, and compare with current 65 year-old aging population. Methods: Analysis method used an estimating formula devised by the researcher and estimated the number of chronic disease patients and medical care expenditure of each generation. Results: When comparing the estimated number of chronic diseases patients of each generation, 40.6% of the first generation, 76.4% of the second generation, 95.2% of third generation are expected to get chronic disease. When comparing each generation's total medical care expenditure, based on the estimated number of chronic diseases patients of each generation, the second generation( 1,206,251,224 thousand won) showed higher than other generation. This study compared the number of chronic disease patients and medical care expenditure between the second generation of the elderly and current elder generation. As a result, the second generation patients was higher than the fourth generation in high blood pressure, diabetes, psychological and behavioral disorder, and neurological diseases whereas the fourth generation is only high the number of patients in heart disease. As for total medical care expenditure, the second generation paid more in high blood pressure, psychological and behavioral disorder while the fourth generation in neurological disease and heart disease. Conclusion: It is desired that considering the number of chronic disease patients and medical care expenditure of baby boomers accounting for 14.6% of total population, in-depth follow-up study is carried out that inquires into what are issues with a current chronic disease management project, what business is needed in order to manage these issues, and how to fund to cover increasing medical care expenditure.

• 융합보안논문지
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• 제16권6_1호
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• pp.3-13
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• 2016

우리는 전쟁에서 당연히 강한 자가 약한 자에게 승리한다고 생각한다. 그러나 현대전쟁에서 약한 자가 강한 자를 상대로 승리한 사례들이 많음을 알 수 있다. 이는 제4세대전쟁 이론을 통해 논리적으로 이해할 수 있다. 북한은 열세한 국력임에도 한반도 무력통일 정책을 포기하지 않고 있다. 그들은 국제사회와 남한을 상대로 다양한 정치 사회 군사적 수준의 도발을 계속하고 있다. 최근에 북한은 5차례의 핵실험, 대륙간탄도미사일 시험발사와, DMZ 도발 등을 자행하였으며, 앞으로도 제4세대전쟁 차원의 도발을 계속할 것으로 예상된다. 이에 점증하고 있는 북한의 제4세대전쟁 위협과 도발에 대한 본질을 이해해야 한다. 이를 통해 그들의 제4세대전쟁 위협에 대한 근본적인 대책중 하나인 향토예비군제도에 대한 가치를 재인식하고 관련 제도를 보완해야 한다. 우리는 개선된 향토예비군제도를 통해 한반도에 세력균형 변화와 힘의 전환점으로 이행을 단호 거부할 수 있다. 즉 예상되는 북한의 제4세대전쟁 위협에 대하여, 우리의 향토예비군제도는 우리의 단호한 전쟁 수행을 위한 의지(意志)이자, 정치 사회 경제 군사적인 수단이며, 최적의 대안으로 기능발휘가 가능하다.

• 대한전자공학회논문지TC
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• 제46권8호
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• pp.50-58
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• 2009

4세대 이동 통신 서비스 망은 기존 서비스 기술을 포함한 포괄된 형태의 기술을 가지게 되며 이를 모두 수용할 수 있는 무선 접속 기술과 망구조로 개발되고 있다. 4세대 이동 통신 시스템에서는 고속 이동 환경과 저속 이동 환경에 적합한 새로운 고속의 무선 접속 기술을 기본으로 하고 있으며 또한, 이 두 시스템간의 자유로운 수직 핸드오버가 가능하도록 설계되고 있다. 한국전자통신연구원에서도 이러한 요구를 만족하는 4세대 이동 통신 시스템인 WiNGS(Wireless Initiative for Next Generation Service) 시스템$^{[1]}$을 설계하고 있다. 본 논문은 4세대 이동통신 시스템의 주요 기술 중 하나인 손실 없는 서비스를 위해 지역 재전송 ARQ 에이전트 설계하였다. WAGW와 WAS간의 ARQ 메커니즘에서 제안하는 WAS에서의 지역 재전송 기법은 ns-2 시뮬레이션 결과 종단간 재전송 방법 보다 패킷 전송 지연 시간 개선과 유선망에서의 불필요한 자원을 사용하지 않도록 하여 보다 안정적인 서비스를 지원할 수 있음을 보였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4651-4654
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• 2013

Choroquine (CQ) and valproic acid (VPA) have been extensively studied for biological effects. Here, we focused on efficacy of combined CQ and VPA on osteosarcoma cell lines. Viability of osteosarcoma cell lines (U20S and HOS) was analyzed by MTT assay. Apoptotic assays and colony formation assays were also applied. ROS generation and Western Blotting were performed to determine the mechanism of CQ and VPA combination in the process of apoptosis. The viability of different osteosarcoma cell lines significantly decreased after CQ and VPA combination treatment compared with either drug used alone, and apoptosis was increased significantly. ROS generation was triggered leading to expression of apoptosis related genes being increased and of antiapoptotic related genes being decreased. From our data shown here, CQ and VPA combination treatment in vitro enhanced cytotoxicy to osteosarcoma cells.

• Journal of Communications and Networks
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• 제4권4호
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• pp.321-335
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• 2002

Emergence of the fourth generation mobile communication system (4G system) is now in its dawn. This article proposes a perspective framework on the 4G system, and discusses various kinds of system aspects and technological requirements in terms of novel service features, spectrum management, radio access technologies, wired access integration, core network, and mobile terminal. The focus of the article is to define the scope and features of the 4G system in an overall system/network viewpoint. From the foreseeable development trends, it is highly expected that whatever emerges in the 4G system will be some kind of constantly evolving and grand recursive concatenation of all the existing system/network developments.

• 한국광학회:학술대회논문집
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• 한국광학회 2003년도 제14회 정기총회 및 03년 동계학술발표회
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• pp.234-235
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• 2003

All solid-state UV lasers provide efficient, clean and semipermanent light sources for various applications, such as eye surgery, microchip lithography. $CsLiB_{6}O_{10}$ (CLBO) is one of the most suitable crystals for UV generation because of its small walk-off, large effective nonlinear susceptibility in UV region and high damage threshold. We produced fourth (266 nm) and fifth (213 nm) harmonic generation of an Nd：YAG laser (1064 nm) with $LiB_{3}O_{5}$ as a second harmonic generation medium and CLBO as a fourth harmonic and fifth harmonic mediums. (omitted)

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 ITC-CSCC -3
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• pp.1459-1462
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• 2002

Emergence of the fourth generation mobile communication system (4G system) is now in its dawn. This paper pro- poses a perspective framework on the 4G system, and discusses system aspects of radio access technologies. The focus of the paper is to define the scope and features of the 4G system in an overall system/network viewpoint. From the foreseeable development trends, it is highly expected that whatever emerges in the 4G system will be some kind of constantly evolving and grand recursive concatenation of all the existing system/network developments.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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• pp.159-163
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• 2004

We have introduced fourth generation PDPs last year. The performance of these PDPs is the highest level among TV displays. At the same time the power consumption of them has reached to the lowest level among FPDs (Flat Panel Displays). High panel luminous efficacy and low address power are necessary for the reduction of total power consumption. Following technologies have been developed and applied to the fourth generation PDPs. High panel luminous efficacy: T-shape electrode, waffle rib structure, high Xe content gas Low address power; CLEAR driving method, etc.

• 한국경영과학회지
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• 제13권1호
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• pp.51-64
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• 1988

A new approach to the logical design of 4NF database shceme, which can be easily automated, is proposed. The main features of the approach are : introduction of a single attribute right hand side, extension of the concept of independent relations, semantic analysis, and adaoption of dependency matrix. The underlying viewpoints of functional relationships of the approach are different from Fagin's in that we distinguish functional and multivalued dependency in terms of cardinality. An algorithm for automatic generation of fourth normal form is presented and implemented.

• Molecules and Cells
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• 제38권11호
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• pp.959-965
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• 2015

Inducible and reversible gene silencing in desired types of cells is instrumental for deciphering gene functions using cultured cells or in vivo models. However, efficient conditional gene knockdown systems remain to be established. Here, we report the generation of an inducible expression system for short hairpin RNA (shRNA) targeted to PTEN, a well-documented dual-specificity phosphatase involved in tumor suppression and ontogenesis. Upon induction by doxycycline (DOX), the reverse tetracycline transcriptional activator (rtTA) switched on the concomitant expression of GFP and a miR-30 precursor, the subsequent processing of which released the embedded PTEN-targeted shRNA. The efficacy and reversibility of PTEN knockdown by this construct was validated in normal and neoplastic cells, in which PTEN deficiency resulted in accelerated cell proliferation, suppressed apoptosis, and increased invasiveness. Transgenic mice harboring the conditional shRNA-expression cassette were obtained; GFP expression and concurrent PTEN silencing were observed upon ectopic expression of rtTA and induction with Dox. Therefore, this study provides novel tools for the precise dissection of PTEN functions and the generation of PTEN loss of function models in specific subsets of cells during carcinogenesis and ontogenesis.