• Health Policy and Management
• /
• v.23 no.4
• /
• pp.376-386
• /
• 2013

Purpose: The purpose of study is to estimate the number of chronic disease patients and medical care expenditure at the time baby-boomers belong to 65 years old aging population, and compare with current 65 year-old aging population. Methods: Analysis method used an estimating formula devised by the researcher and estimated the number of chronic disease patients and medical care expenditure of each generation. Results: When comparing the estimated number of chronic diseases patients of each generation, 40.6% of the first generation, 76.4% of the second generation, 95.2% of third generation are expected to get chronic disease. When comparing each generation's total medical care expenditure, based on the estimated number of chronic diseases patients of each generation, the second generation( 1,206,251,224 thousand won) showed higher than other generation. This study compared the number of chronic disease patients and medical care expenditure between the second generation of the elderly and current elder generation. As a result, the second generation patients was higher than the fourth generation in high blood pressure, diabetes, psychological and behavioral disorder, and neurological diseases whereas the fourth generation is only high the number of patients in heart disease. As for total medical care expenditure, the second generation paid more in high blood pressure, psychological and behavioral disorder while the fourth generation in neurological disease and heart disease. Conclusion: It is desired that considering the number of chronic disease patients and medical care expenditure of baby boomers accounting for 14.6% of total population, in-depth follow-up study is carried out that inquires into what are issues with a current chronic disease management project, what business is needed in order to manage these issues, and how to fund to cover increasing medical care expenditure.

• Convergence Security Journal
• /
• v.16 no.6_1
• /
• pp.3-13
• /
• 2016

We take it for granted that strong sides defeat weaker counterparts, while predicting the outcome of the battles. But in modern war, we can find plenty of evidence that weak sides won against the strong. This phenomenon can be understood logically by the fourth-generation war theory. the North Korean does not give up its unification strategy, which is unification by force, even though its inferior power. It is continuing various political, social and military levels of provocations toward both the international community and South Korea. Recently, North Korea did nuclear test, launched ICBM test, provoked the DMZ, and expecting to continue the provocations of the fourth-generation war level. We have to understand the nature of North Korea's fourth-generation war threats and provocations that it is focusing on. Based on this, have a new understanding of the value of the Homeland Defense Reservists as fundamental measures as the fourth-generation war threat and supplement related systems. We can firmly refuse the balance of power and power shift of the Korean Peninsula through improved Homeland Defense Reservists. As the expected North Korea's the fourth-generation war threats, our Homeland Defense Reservists is a firm will of conduct war, and political-social-economic-military means, it is possible to display as the best alternative.

• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.46 no.8
• /
• pp.50-58
• /
• 2009

Fourth generation mobile communication network have the technology of extensive form include basic service technology and it has been developed from the radio access technology and network topology. Not only fourth generation mobile communication network have basically done new highspeed radio access technology which is suitable to high and low speed environment of transfer, but also it is possible that they have been made for freely vertical handover. ETRI also has made fourth generation mobile communication network which is WiNGS(Wireless Initiative for Next Generation Service) satisfied that demand. This paper is made by lossless handover method through the local retransmission ARQ agent that is one of the main technology of fourth generation mobile communication network. Lossless handover method through local retransmission ARQ agent has been basically made by WiNGS and it was better than original local retransmission of layer by simulation.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.8
• /
• pp.4651-4654
• /
• 2013

Choroquine (CQ) and valproic acid (VPA) have been extensively studied for biological effects. Here, we focused on efficacy of combined CQ and VPA on osteosarcoma cell lines. Viability of osteosarcoma cell lines (U20S and HOS) was analyzed by MTT assay. Apoptotic assays and colony formation assays were also applied. ROS generation and Western Blotting were performed to determine the mechanism of CQ and VPA combination in the process of apoptosis. The viability of different osteosarcoma cell lines significantly decreased after CQ and VPA combination treatment compared with either drug used alone, and apoptosis was increased significantly. ROS generation was triggered leading to expression of apoptosis related genes being increased and of antiapoptotic related genes being decreased. From our data shown here, CQ and VPA combination treatment in vitro enhanced cytotoxicy to osteosarcoma cells.

• Journal of Communications and Networks
• /
• v.4 no.4
• /
• pp.321-335
• /
• 2002

Emergence of the fourth generation mobile communication system (4G system) is now in its dawn. This article proposes a perspective framework on the 4G system, and discusses various kinds of system aspects and technological requirements in terms of novel service features, spectrum management, radio access technologies, wired access integration, core network, and mobile terminal. The focus of the article is to define the scope and features of the 4G system in an overall system/network viewpoint. From the foreseeable development trends, it is highly expected that whatever emerges in the 4G system will be some kind of constantly evolving and grand recursive concatenation of all the existing system/network developments.

• Proceedings of the Optical Society of Korea Conference
• /
• 2003.02a
• /
• pp.234-235
• /
• 2003

All solid-state UV lasers provide efficient, clean and semipermanent light sources for various applications, such as eye surgery, microchip lithography. $CsLiB_{6}O_{10}$ (CLBO) is one of the most suitable crystals for UV generation because of its small walk-off, large effective nonlinear susceptibility in UV region and high damage threshold. We produced fourth (266 nm) and fifth (213 nm) harmonic generation of an Nd：YAG laser (1064 nm) with $LiB_{3}O_{5}$ as a second harmonic generation medium and CLBO as a fourth harmonic and fifth harmonic mediums. (omitted)

• Proceedings of the IEEK Conference
• /
• 2002.07c
• /
• pp.1459-1462
• /
• 2002

Emergence of the fourth generation mobile communication system (4G system) is now in its dawn. This paper pro- poses a perspective framework on the 4G system, and discusses system aspects of radio access technologies. The focus of the paper is to define the scope and features of the 4G system in an overall system/network viewpoint. From the foreseeable development trends, it is highly expected that whatever emerges in the 4G system will be some kind of constantly evolving and grand recursive concatenation of all the existing system/network developments.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2004.08a
• /
• pp.159-163
• /
• 2004

We have introduced fourth generation PDPs last year. The performance of these PDPs is the highest level among TV displays. At the same time the power consumption of them has reached to the lowest level among FPDs (Flat Panel Displays). High panel luminous efficacy and low address power are necessary for the reduction of total power consumption. Following technologies have been developed and applied to the fourth generation PDPs. High panel luminous efficacy: T-shape electrode, waffle rib structure, high Xe content gas Low address power; CLEAR driving method, etc.

• Journal of the Korean Operations Research and Management Science Society
• /
• v.13 no.1
• /
• pp.51-64
• /
• 1988

A new approach to the logical design of 4NF database shceme, which can be easily automated, is proposed. The main features of the approach are : introduction of a single attribute right hand side, extension of the concept of independent relations, semantic analysis, and adaoption of dependency matrix. The underlying viewpoints of functional relationships of the approach are different from Fagin's in that we distinguish functional and multivalued dependency in terms of cardinality. An algorithm for automatic generation of fourth normal form is presented and implemented.

• Molecules and Cells
• /
• v.38 no.11
• /
• pp.959-965
• /
• 2015

Inducible and reversible gene silencing in desired types of cells is instrumental for deciphering gene functions using cultured cells or in vivo models. However, efficient conditional gene knockdown systems remain to be established. Here, we report the generation of an inducible expression system for short hairpin RNA (shRNA) targeted to PTEN, a well-documented dual-specificity phosphatase involved in tumor suppression and ontogenesis. Upon induction by doxycycline (DOX), the reverse tetracycline transcriptional activator (rtTA) switched on the concomitant expression of GFP and a miR-30 precursor, the subsequent processing of which released the embedded PTEN-targeted shRNA. The efficacy and reversibility of PTEN knockdown by this construct was validated in normal and neoplastic cells, in which PTEN deficiency resulted in accelerated cell proliferation, suppressed apoptosis, and increased invasiveness. Transgenic mice harboring the conditional shRNA-expression cassette were obtained; GFP expression and concurrent PTEN silencing were observed upon ectopic expression of rtTA and induction with Dox. Therefore, this study provides novel tools for the precise dissection of PTEN functions and the generation of PTEN loss of function models in specific subsets of cells during carcinogenesis and ontogenesis.