• 제목/요약/키워드: The Comparative Analysis

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Bridging Comparative Genomics and DNA Marker-aided Molecular Breeding

  • Choi, Hong-Kyu;Cook, Douglas R.
    • 한국육종학회지
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    • 제43권2호
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    • pp.103-114
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    • 2011
  • In recent years, genomic resources and information have accumulated at an ever increasing pace, in many plant species, through whole genome sequencing, large scale analysis of transcriptomes, DNA markers and functional studies of individual genes. Well-characterized species within key plant taxa, co-called "model systems", have played a pivotal role in nucleating the accumulation of genomic information and databases, thereby providing the basis for comparative genomic studies. In addition, recent advances to "Next Generation" sequencing technologies have propelled a new wave of genomics, enabling rapid, low cost analysis of numerous genomes, and the accumulation of genetic diversity data for large numbers of accessions within individual species. The resulting wealth of genomic information provides an opportunity to discern evolutionary processes that have impacted genome structure and the function of genes, using the tools of comparative analysis. Comparative genomics provides a platform to translate information from model species to crops, and to relate knowledge of genome function among crop species. Ultimately, the resulting knowledge will accelerate the development of more efficient breeding strategies through the identification of trait-associated orthologous genes and next generation functional gene-based markers.

한ㆍ일 수산물 수출입 경쟁구조 분석 (An Analysis on the Competitive Structure of Fishery Products Export & Import between Korea and Japan)

  • 최정윤;김정봉
    • 수산경영론집
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    • 제34권2호
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    • pp.141-164
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    • 2003
  • This study analysis the market status and competitive structure of Korean fishery in Japan import market, and derive policy implications for seeking main causes. Specifically', trade state between Korea and Japan is discovered and theoretical model is also used to analysis competitiveness between two countries. And then real measuring methods of competitive index is Introduced, the status of Korean fishery products in Japan import market is analysed totally through the study of comparative predominance and export competition. The analysis is based on the statistical methods such as RCA, RMI, and CMS. In summary, first, Korean fishery products have the comparative predominance in Japan, China and Thailand, but they have the comparative inferiority in USA, considering research results. Second, competitiveness of fishery products between Korea and in Japan import market extreme, relatively, competitiveness of Korean fishery products for Thailand's fishery products is lowest. Third, Korean fishery products maintain unconstant pattern, but competitive inputs result in increasing export to Japan generally.

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정량적인 구조-활성상관 (QSAR) 기법에 의한 새로운 농약의 개발. III. 3D QSAR 기법들과 컴퓨터를 이용한 분자설계(CAMD) (Development of new agrochemicals by quantitative structure-activity relationship (QSAR) methodology. III. 3D QSAR methodologies and computer-assisted molecular design (CAMD))

  • 성낙도
    • 농약과학회지
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    • 제7권1호
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    • pp.1-11
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    • 2003
  • 새로운 농약을 탐색하고 개발하는데 있어서 고효율 유기함성 (HTOS) 기술과 고효율 검색 (HTS) 기술 등의 발전과 더불어 컴퓨터 화학을 이용한 분자설계 (CAMD) 방법으로 보편화되고 있는 비교 분자장 분석(CoMFA)과 비교 분자 유사성 지수분석(CoMSIA) 등, 3D QSAR 기법들을 위시하여 분자 홀로그램 구조 - 활성관계 (HQSAR) 분석방법 등, QSAR 기법들을 요약하고 그 활용 사례들을 간략하게 소개하였다.

Exploratory Autopsy on Digital Payment Models

  • Wang, Tao;Kim, Chang-Su;Kim, Ki-Su
    • 한국경영정보학회:학술대회논문집
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    • 한국경영정보학회 2007년도 International Conference
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    • pp.646-651
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    • 2007
  • Secure digital payment is critical in the successful shaping of global digital business. Digital payments are increasingly being used as a substitute to traditional payments, contributing markedly to the efficiency of the economy. The focus of every digital business transaction is to minimize risks arising from transactions. It is essential to ensure the security of digital payment whether used in internal networks or over wireless Internet. This paper analyses secure digital payment methods from the viewpoint of systemic security and transaction security. According to comparative analysis of digital payment models, this paper proposes a comparative analysis framework to investigate and evaluate secure digital payment. In conclusion, the comparative analysis framework, comparison of digital payment models and mobile payment models proposes a useful academic and practical foundation to enhance the understanding of secure digital payment methods. It also provides academic background and practical guidelines for the development of secure digital payment systems.

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Comparison of QSAR Methods (CoMFA, CoMSIA, HQSAR) of Anticancer 1-N-Substituted Imidazoquinoline-4,9-dione Derivatives

  • Suh, Myung-Eun;Park, So-Young;Lee, Hyun-Jung
    • Bulletin of the Korean Chemical Society
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    • 제23권3호
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    • pp.417-422
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    • 2002
  • Comparison studies of the Quantitative Structure Activity Relationship (QSAR) methods with new imidazo-quinolinedione derivatives were conducted using Comparative Molecular Field Analysis (CoMFA), Comparative Molecular Similarity Indices Analysis (CoMSIA), and the Hologram Quantitative Structure Activity Relationship (HQSAR). When the CoMFA crossvalidation value, q2, was 0.625, the Pearson correlation coefficient, r2, was 0.973. In CoMSIA, q2 was 0.52 and r2 was 0.979. In the HQSAR, q2 was 0.501 and r2 was 0.924. The best result was obtained using the CoMSIA method according to a comparison of the calculated values with the real in vitro cytotoxic activities against human ovarian cancer cell lines.

생활체육정책 유형에 관한 국가 간 비교연구 (International Comparative Study on Sports for All Policy Patterns)

  • 조욱연
    • 한국콘텐츠학회논문지
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    • 제12권4호
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    • pp.457-467
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    • 2012
  • 본 연구는 생활체육이 비교적 잘 발달되어 있는 OECD 국가들을 대상으로 생활체육정책의 국가 간 상이한 유형을 밝혀내고 그 원인이 무엇인지 밝혀내는데 그 목적이 있다. 이를 위해 생활체육이 비교적 잘 발달되어 있는 OECD 30개 국가 중 관련 자료의 취득이 가능한 26개국을 연구대상으로 삼았다. 그리고 군집분석을 통해 유형화된 국가들의 결정요인을 질적비교분석(Qualitative Comparative Analysis: QCA)을 이용하여 분석하였다. 질적비교분석을 위한 원인변수로는 1인당 GDP, 여가시간, 공공사회복지지출(SOCX), 지니계수, 빈곤율, 조세부담률을 선정하였다. 이러한 과정을 통하여 얻은 연구결과는 다음과 같다. 첫째, 분석대상 26개 국가들을 생활체육참여율과 스포츠클럽참여율을 기준으로 군집화하여 국가별로 유형한 결과 세 가지의 유형을 발견하였으며, 한국은 생활체육참여율과 스포츠클럽참여율이 낮은 유형으로 나타났다. 둘째, 국가별 생활체육정책의 유형이 발생하는 결정요인을 파악하기 위하여 질적비교분석을 실시해 본 결과 한국이 속한 유형은 GDP, 여가시간, 공공사회복지지출(SOCX), 조세부담률과 부의 관계를 나타내며, 지니계수와 빈곤율과는 정의 관계를 나타냈다.

Molecular Docking, 3D QSAR and Designing of New Quinazolinone Analogues as DHFR Inhibitors

  • Yamini, L.;Kumari, K. Meena;Vijjulatha, M.
    • Bulletin of the Korean Chemical Society
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    • 제32권7호
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    • pp.2433-2442
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    • 2011
  • The three dimensional quantitative structure activity relationship (3D QSAR) models were developed using Comparative molecular field analysis (CoMFA), comparative molecular similarity indices analysis (CoMSIA) and docking studies. The fit of Quinazolinone antifolates inside the active site of modeled bovine dihydrofolate reductase (DHFR) was assessed. Both ligand based (LB) and receptor based (RB) QSAR models were generated, these models showed good internal and external statistical reliability that is evident from the $q^2_{loo}$, $r^2_{ncv}$ and $r^2_{pred}$. The identified key features enabled us to design new Quinazolinone analogues as DHFR inhibitors. This study is a building bridge between docking studies of homology modeled bovine DHFR protein as well as ligand and target based 3D QSAR techniques of CoMFA and CoMSIA approaches.

청소년 여학생(靑少年 女學生)과 성인 여성(成人 女性)의 브래지어 패턴 비교연구(比較硏究) (A Study on the Comparative Analysis of Brassiere Pattern between Girl Students and Adults)

  • 손희순;차수정
    • 패션비즈니스
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    • 제10권4호
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    • pp.95-113
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    • 2006
  • This study was conducted comparative analysis of juvenile brassiere and adult brassiere to identify the problems of brassieres on the market. The raw data for this study was processed by SPSS 10.1 version(statistical software) and the results of this study can be summarized as follows. 1) The result of comparative analysis of juvenile brassiere and adult brassiere pattern is that each pattern showed no difference. 2) The results of the comparative analysis of juvenile and adult brassiere pattern in wing's length and angle is that even though there are some difference between juvenile and adult in side line inclination of brassiere. there is no setting difference but size of that brassiere. 3) The result of a comparative analysis pattern and cup size measurement of juvenile brassiere and adult brassiere is that even though the adult cup girth and angle is bigger than the juvenile because adults have more protrusive and bigger volume and well developed breast, some case rather the adult's cup angle is smaller than the juvenile as brand. And as we grow up to be a woman, difference of lower breast girth and breast girth are become big while difference of upper breast girth and breast girth are become small for that reason upper cup must be lower and lower cup must be higher but there is almost no difference between adult and juvenile. 4) The result of a comparative analysis of juvenile brassiere and adult brassiere bust point of the pattern is that adult brassiere's distance between bust points 6.12cm, and juvenile's 5.6cm, there are only 0.52cm difference between two products and just 0.4cm, size grading. These results are explained that even though when grow up to be a woman the distance between two bust points become to be long and breast toward out side but brassiere size don't vary with body characteristic.

비교교육학과 교육평가학 (Comparative Education and Educational Evaluation)

  • 박찬호
    • 비교교육연구
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    • 제28권1호
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    • pp.135-151
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    • 2018
  • 이 논문은 교육평가학과의 관계를 점검함으로써 비교교육학의 학문적 위상을 정립하는 데 도움을 주려는 목적으로 작성되었다. 비교교육학은 교육학의 분과 학문이면서 교육학의 다른 분과 학문들을 포괄할 수도 있다는 점에서 독특한 성격을 지닌다. 그리고 교육평가학은 평가의 내용을 다루기도 하지만 평가 방법론이 연구 영역에 포함된다는 특징을 지닌다. 교육평가학과 비교교육학 간 접점으로는 먼저 점차 확대되고 있는 국제비교평가를 들 수 있다. 국제비교평가는 1960년대 12개국의 수학교육을 비교하기 위해 실시된 국제수학연구를 필두로 대상 과목과 참여국가가 점점 확대되고 있다. 국제비교평가는 단지 참여국의 순위 경쟁이 목적이 아니라 각국의 교육과정 및 교육실천을 다각도로 비교함으로써 교육 개선을 위한 시사점을 제공하기 위해 실시되고 있다. 국제비교평가에는 다집단 분석을 실시할 수 있으며, 특히 국가 간 사회문화적 차이 등 측정구인 외의 요소가 어떻게 작용하고 있는지 밝히는 차별적 문항기능 분석이 가능하다. 또한 국제비교평가 자료는 다른 교육 자료들과 마찬가지로 위계적 구조를 지니고 있어 다층모형 또는 위계적선형모형이 적절하다. 따라서 문항반응이론을 확장시킨 다층문항반응이론을 적용할 수 있으며, 이를 통해 국가 간 차이에 대한 다차원적 진단이 가능하다. 교육평가학의 방법론적 진보에도 불구하고 비교 교육학과의 간극으로 인해 그 도구들은 적절히 사용되지 못하고 있다. 이를 해결함으로써 비교 교육학은 학문으로서 진일보할 수 있을 것이다. 결론적으로 방법론을 쉽게 풀어 널리 알림으로써 연구자가 도구를 손쉽게 사용할 수 있도록 하는 교육평가 학계의 노력과 함께 이러한 도구들을 사용함으로써 보다 정밀하고 정확한 분석을 통해 정책적 시사점을 도출하고자 하는 비교교육 연구자들의 노력이 함께 요구된다.