• 한국정보과학회논문지:시스템및이론
• /
• 제35권2호
• /
• pp.75-83
• /
• 2008

Joye와 연구자들은 기존의 조합 소수 판단 검사에서 trial division 과정을 제거한 새로운 소수 생성 알고리즘 (이하 JPV 알고리즘)을 제시하였으며, 이 알고리즘이 기존의 조합 소수 생성 알고리즘에 비해 $30{\sim}40%$ 정도 빠르다고 주장하였다. 하지만 이 비교는 전체 수행시간이 아닌 Fermat 검사의 호출 횟수만을 비교한 것으로 정확한 비교와는 거리가 있다. 기존의 조합 소수 생성 알고리즘에 대해 이론적인 수행시간 예측 방법이 있음에도 불구하고 두 알고리즘의 전체 수행시간을 비교할 수 없었던 이유는 JPV 알고리즘에 대한 이론적인 수행 시간 예측 모델이 없었기 때문이다. 본 논문에서는 먼저 JPV 알고리즘을 확률적으로 분석하여 수행시간 예측 모델을 제시하고, 이 모델을 이용하여 JPV 알고리즘과 기존의 조차 소수 생성 알고리즘의 전체 수행시간을 비교한다. 이 모델을 이용하여 펜티엄4 시스템에서 512비트 소수의 생성 시간을 예측해 본 결과 Fermat 검사의 호출 횟수를 이용한 비교와는 달리 JPV 알고리즘이 기존의 조합 소수 생성 알고리즘보다 느리다는 결론을 얻었다. 이러한 이론적인 분석을 통한 비교는 실제 동일한 환경에서 실험을 통해서 검증되었다. 또한, 본 논문에서는 JPV 알고리즘의 성능 개선 방법을 제시한다. 이 방법을 사용하여 JPV 알고리즘을 개선하면 동일한 공간을 사용할 경우에 JPV 알고리즘이 기존의 조합 소수 생성 알고리즘과 비슷한 성능을 보인다.

• Journal of Information Processing Systems
• /
• 제13권4호
• /
• pp.928-940
• /
• 2017

State-of-the-art speaker recognition systems may work better for the English language. However, if the same system is used for recognizing those who speak different languages, the systems may yield a poor performance. In this work, the decisions of a Gaussian mixture model-universal background model (GMM-UBM) and a learning vector quantization (LVQ) are combined to improve the recognition performance of a multilingual speaker identification system. The difference between these classifiers is in their modeling techniques. The former one is based on probabilistic approach and the latter one is based on the fine-tuning of neurons. Since the approaches are different, each modeling technique identifies different sets of speakers for the same database set. Therefore, the decisions of the classifiers may be used to improve the performance. In this study, multitaper mel-frequency cepstral coefficients (MFCCs) are used as the features and the monolingual and cross-lingual speaker identification studies are conducted using NIST-2003 and our own database. The experimental results show that the combined system improves the performance by nearly 10% compared with that of the individual classifier.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권14호
• /
• pp.5889-5897
• /
• 2015

Background: The performance of combined testing visual inspection with acetic acid (VIA) and cervical cytology tests might differ from one setting to another. The average estimate of the testing accuracy across studies is informative, but no meta-analysis has been carried out to assess this combined method. Objective: The objective of this study was to estimate the average sensitivity and specificity of the combined VIA and cervical cytology tests for the detection of cervical precancerous lesions. Materials and Methods: We conducted a systematic review and a meta-analysis, according to the Cochrane Handbook for Systematic Review of Diagnostic Test Accuracy. We considered two cases. In the either-positive result case, a positive result implies positivity in at least one of the tests. A negative result implies negativity in both tests. In the both-positive case, a positive result implies having both tests positive. Eligible studies were identified using Pubmed, Embase, Website of Science, CINHAL and COCRANE databases. True positive, false positive, false negative and true negative values were extracted. Estimates of sensitivity and specificity, positive and negative likelihood (LR) and diagnostic odds ratios (DOR) were pooled using a hierarchical random effect model. Hierarchical summary receiver operating characteristics (HSROC) were generated and heterogeneity was verified through covariates potentially influencing the diagnostic odds ratio. Findings: Nine studies fulfilled inclusion criteria and were included in the analysis. Pooled estimates of the sensitivities of the combined tests in either-positive and both-positive cases were 0.87 (95% CI: 0.83-0.90) and 0.38 (95% CI: 0.29-0.48), respectively. Corresponding specificities were 0.79 (95% CI: 0.63-0.89) and 0.98 (95% CI: 0.96-0.99) respectively. The DORs of the combined tests in either-positive or both-positive result cases were 27.7 (95% CI: 12.5-61.5) and 52 (95% CI: 22.1-122.2), respectively. When including only articles without partial verification bias and also a high-grade cervical intraepithelial neoplasia as a threshold of the disease, DOR of combined test in both-positive result cases remained the highest. However, DORs decreased to 12.1 (95% CI: 6.05-24.1) and 13.8 (95% CI: 7.92-23.9) in studies without partial verification bias for the combined tests in the either-positive and both-positive result cases, respectively. The screener, the place of study and the size of the population significantly influenced the DOR of combined tests in the both-positive result case in restriction analyses that considered only articles with CIN2+ as disease threshold. Conclusions: The combined test in the either-positive result case has a high sensitivity, but a low specificity. These results suggest that the combined test should be considered in developing countries as a primary screening test if facilities exist to confirm, through colposcopy and biopsy, a positive result.

• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 1999년도 추계 학술대회논문집
• /
• pp.152-157
• /
• 1999

For the simulation of the blood flow in coronary artery, the system modeling of coronary hemodynamics is combined with CFD technique. The blood flow in coronary artery interacts with the global coronary circulation. Especially in case of the coronary artery with stenosis, the interaction plays an important role in the hemodynamics of the circulation. In this study we present a combined numerical approach using both the CFD technique for flow simulation and the global system model of coronary circulation. We use a lumped parameter model for the global simulation of coronary circulation whereas the finite element method is employed to compute the viscous flow field in stenosed coronary artery, The time variation of the pressure drop due to stenosis is obtained from the proposed numerical method. Numerical results shows that the flow resistance and pressure drop due to stenosis has a relatively large value in systole.

• Journal of the Optical Society of Korea
• /
• 제14권1호
• /
• pp.55-62
• /
• 2010

We introduce a new method for lens design that combines an eyepiece with the finite model eye, to make a corrected version of the accommodation-dependent Navarro eye. The optical system that we designed, which includes a human eye, takes into account the aberration of the eye and increases the performance of the image in the retina. In the design results, for the optimized eyepiece combined with the corrected Navarro eye, visual acuity is 1.40. Compared with the existing method of eyepiece design using inverse ray tracing with the corrected Navarro eye, MTF value was recorded as 0.079 to 0.283 at 160 lp/mm and visual performance was improved.

• Steel and Composite Structures
• /
• 제33권2호
• /
• pp.245-259
• /
• 2019

The present study aims to investigate the ultimate strength and geometric nonlinear behavior of composite plates containing initial imperfection subjected to combined end-shortening strain and lateral pressure loading by using a semi-analytical method. In this study, the first order shear deformation plate theory is considered with the assumption of large deflections. Regarding in-plane boundary conditions, two adjacent edges of the laminates are completely held while the two others can move straightly. The formulations are based on the concept of the principle of minimum potential energy and Newton-Raphson technique is employed to solve the nonlinear set of algebraic equations. In addition, Hashin failure criteria are selected to predict the failures. Further, two distinct models are assumed to reduce the mechanical properties of the failure location, complete ply degradation model, and ply region degradation model. Degrading the material properties is assumed to be instantaneous. Finally, laminates having a wide range of thicknesses and initial geometric imperfections with different intensities of pressure load are analyzed and discuss how the ultimate strength of the plates changes.

• 한국지하수토양환경학회:학술대회논문집
• /
• 한국지하수토양환경학회 1998년도 공동 심포지엄 및 추계학술발표회
• /
• pp.123-126
• /
• 1998

We have conducted surface electrical resistivity surveys along with the electrical logging at Bookil-Myun, Chungwon-Goon, Choongchungbuk-Do to determine the depths of basement and water table, and for the purpose of preparing the basic input data for hydrogeologic model combined with GIS. A twenty lines of dipole-dipole array survey and a twenty-five stations of resistivity sounding were performed and ten holes were employed for electrical logging to cross check the surface data. A combined interpretation gave the quantitative information of the shallow geologic structure over the area and we constructed layers using the grid analysis of Arc/info. The constructed layers were turned out to be similar to the geologic structure confirmed from the drilling data and we concluded that the methodology adopted in this study would be applicable to hydrogeologic model setup as a tool of providing the basic input data.

• 한국항만학회지
• /
• 제8권2호
• /
• pp.67-77
• /
• 1994

A time-domain numerical model is developed to examine the performance of a wave energy focusing structure in combined waves and a current. With the current assumed to be slow and the structure fully submerged, the wave-current interaction problem is reduced to a wave scattering problem in a uniform current. The diffraction of incident waves around a narrow berm is considered. The shape of the berm is defined by a parabola, imitating that of an optical reflector. The energy focus is achieved by reflecting the incident waves through a predetermined focal point. Through the numerical simulations, the numerical model is shown to be effective in modeling the wave-current interaction problem, and the current speed and direction are shown to affect significantly the location, amplitude and sharpness of the focus.

• 생명과학회지
• /
• 제22권9호
• /
• pp.1145-1151
• /
• 2012

아스피린과 아스피린의 deacetylated form인 sodium salicylate (NaSal)은 대장암, 폐암 및 유방암을 비롯한 다양한 암의 항암제 활성을 나타내는 것으로 잘 알려져 있다. A549 폐암 세포주에 저농도의 NaSal과 genistein을 함께 복합 처리시 상승작용에 의해 세포사멸을 증가시켜서 NaSal에 의한 암억제 효과를 증대시킴을 이미 밝힌바 있다. 본 연구에서는 A549가 아닌 다른 암세포주와 in vitro solid tumor model인 multicellular spheroids (MTS)을 이용하여 NaSal과 genistein 복합처리 효과를 조사하였다. NaSal/genistein 복합 처리시 A549 세포주와 마찬가지로 HCT116 세포주에서도 세포사멸이 유도되었지만, MCF-7 세포주에서는 유도되지 않았다. 흥미롭게도, MCF-7 세포주는 MTS로 배양되는 동안 NaSal/genistein 복합 처리에 의해 세포 죽음을 나타내었다. 세포 죽음의 형태는 MCF-7 MTS의 발달 단계에 따라 세포사멸 또는 세포괴사로 나타났다. MCF-7 MTS에서의 세포사멸은 불완전한 양상을 보였다. 즉 염색체가 응축되고 쪼개지지만, 핵막은 여전히 관찰되었다. 이상의 연구 결과 NaSal/genistein 복합처리는 MCF-7 MTS 배양 system에서 불완전한 세포사멸과 세포괴사를 일으킴을 알 수 있었다.

• 한국해양공학회지
• /
• 제12권1호
• /
• pp.50-57
• /
• 1998

The leak before break(LBB) concept is generalized on the design of LNG tanks, pressure vessels and nuclear reactor in that any leakage of containment, in whatever amount, will not result in catastropic failure. For this purpose it is necessary to determine the surface crack shape, the opening displacement and the risk of catastropic brittle fracture when it becomes a through crack. In this study the crack propagation behavior of surface flaws and the crack opening displacement of through cracks under combined membrane and bending stresses were investigated with fatigue tests and fracture toughness test of aluminium alloy A5083-O. And fracture mechanics analysis of the crack opening displacement of through cracks were made in order to develop a new model expressing the behaviors of COD under combined membrane and bending stresses.