• Korean Journal of Veterinary Research
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• v.60 no.4
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• pp.203-207
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• 2020

This study presents neuronal migration pattern of dopamine (DA) neurons generated in separate regions occupying the ventral mesencephalic territory. A single pulse 5-bromodeoxyuridine (BrdU) was administered at embryonic day (E)10-E15. Distribution of tyrosine hydroxylase (TH) positive cells was determined at E13-postnatal day 0 (P0) by immunohistochemistry. BrdU positive cells labeled at E10 were spread out uniformly in the mesencephalon from E13 to E15, migrating through dorsal and ventral routes at E17 and P0. TH expression labeled at E10 was observed at E13 in the ventromedial region and clearly formed in the ventral tegmental area (VTA) at E15. At E17, TH expression in the substantia nigra (SN) was observed in the ventrolateral region, spreading more outward of the mesencephalon at P0. Generation of TH-positive cells labeled at E13 was also observed in VTA and SN of the mesencephalon at E17 and P0. The expression of these cells labeled after E15 was markedly decreased. These results demonstrated that an almost complete primary structure of DA neuron was formed at the early embryonic stage in the ventral mesencephalon, showing the most active neuronal migration was occurred at E13-E17.

• Sijohaknonchong
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• v.44
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• pp.197-236
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• 2016

The aim of this study is to discover the distinctive aspects of Sijo in the 17th Century through five old music scores, "梁琴新譜Yangqeumsinbo", "白雲庵琴譜 baekwoonamgeumbo", "增補古琴譜jeungbogogeumbo", "延世大學校所藏琴譜geumbo in Yonsei University", "琴譜古geumbogo", which were compiled in this time period. First, four Sijo works are found from the "梁琴新譜Yangqeumsinbo" and one of them is noteworthy because it was sung as 中大葉Jungdaeyeop, 初中大葉 Chojungdaeyeop, 二中大葉Yijungdaeyeop and showed signs to fit the Sijo format type since the 17th century. In "白雲庵琴譜baekwoonamgeumbo", there are three Sijo works (one has recorded music scores and two don't) and one of them is discovered with last phrase being omitted. In "延世大學校所藏琴譜geumbo in Yonsei University", there are 9 Sijo works performed with 中大葉Jungdaeyeop. In "增補古琴譜 jeungbogogeumbo", there are three works performed with 數大葉Sakdaeyeop and one of them is noteworthy as a clue about the relations between Sijo and Goryeosokyo because it is a modified work which adapted the Goryeosokyo "Gasiri" according to the Sijo format. In 琴譜古geumbogo, there are three works with high possibility that repertoire with 中大葉Jungdaeyeop were already set up at this time. Based on these five music scores, it can be mentioned that a lot of Geumbos were compiled in 17th century, not for the purpose of enlightening discourse at the national level but for referencing for music lovers by themselves to memorize songs individually. It is also discovered that Sijo was performed with only 平調pyeong-jo out of 羽調woo-jo, 羽調界面調woojokyemyen-jo, 平調pyeong-jo, 平調界面調pyeongjokyemyun-jo in early 17th century, but it was performed with other three and 數大葉Sakdaeyeop as well after the mid-17th century. On the other hand, despite the change in the musical tunes, lyrics do not show a significant change at this time because it is estimated repertoire with specific piece of music was already formed in 17th Century. However, performing itself would give a certain impact on change and loss of lyrics because it tends to focus on communication and emotional connection between singers and audience. Clarifying characteristics in Sijo from old music scores is meaningful in that Sijo can be understood better not only as written poetry but also as oral poetry and overcome bias of previous researches which have been proceeded mainly on Sijo lyrics collection(歌集).

• Journal of architectural history
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• v.27 no.3
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• pp.15-26
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• 2018

As a result of reviewing various documents and existing researches, since the late Goryeo period, the most active period in the Ondol(溫突, Korean floor heating system) facilities is the 17th century. The phenomenological reason was recovering the buildings destroyed by the Japanese Invasion of Korea in 1592(壬辰倭亂) & the Manchu War of 1636(丙子胡亂), but the underlying cause was an abnormal climate in which a pair of summer and winter cold continued. In the 17th century, as the Ondol facilities grew rapidly without distinction between regions and classes, the supply and demand of fuel caused economic and natural environmental problems. And a negative and positive view on Ondol was suggested. Since the middle of the 18th century, when the demand and supply of Ondol reached its peak, which could no longer increase, a new awareness of Ondol began to grow. The room was called the Panbang(板房) and the Ondol, depending on the material that made up the floor. It was considered natural to have the Ondol from this time on. The Incan(因間) and Jo(竈) that were made to burn were started to be recorded as a kitchen, regardless of size and function. Changes in social awareness of Ondol have led to concerns about heating efficiency. A variety of architectural explorations were conducted. Such a search was later realized in concrete architectural form. There is a double Ondoll structure, and the column spacing is reduced compared to the previous one. The heat buffer space is formed around the Ondol room, and the double window can control the light and the air going in and out.

• The Korean Journal of Applied Statistics
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• v.32 no.4
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• pp.503-515
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• 2019

In this study we estimate the survival function of duration of the legislative processes in the 17th, 18th, and 19th National Assembly of Korea, and further analyze effects of the political situation variables on the legislative process. We define the termination of legislative process from a novel perspective to alleviate issues of dependency between censoring and failure in the data. We also show that the proportional hazards assumption does not hold for the data, and analyze data employing a log-normal accelerated failure time model. The policy areas of law agendas are shown to affect the speed of legislative process in different ways and legislative process tends to be prompt in times of divided governments.

• Journal of Animal Science and Technology
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• v.64 no.6
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• pp.1184-1198
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• 2022

In this study, Rubus coreanus (R. coreanus) byproducts with high polyphenol content were fermented with R. coreanus-derived lactic acid bacteria (Lactobacillus plantarum GBL 16 and 17). Then the effect of R. coreanus-derived lactic acid bacteria fermented feed (RC-LAB fermented feed) with probiotics (Bacillus subtills, Aspergillus oryzae, Yeast) as a feed additive for pigs on the composition of intestinal microbes and the regulation of intestinal immune homeostasis was investigated. Seventy-two finishing Berkshire pigs were randomly allotted to four different treatment groups and 18 replicates. RC-LAB fermented feed with probiotics increased the genera Lactobacillus, Streptococcus, Mitsuokella, Prevotella, Bacteroides spp., Roseburia spp., and Faecalibacterium prausnitzii, which are beneficial bacteria of the digestive tract of pigs. Also, RC-LAB fermented feed with probiotics decreased the genera Clostridium, Terrisporobacter, Romboutsia, Kandleria, Megasphaera and Escherichia, which are harmful bacteria. In particular, the relative abundance of the genera Lactobacillus and Streptococcus increased by an average of 8.51% and 4.68% in the treatment groups and the classes Clostridia and genera Escherichia decreased by an average of 27.05% and 2.85% in the treatment groups. In mesenteric lymph nodes (MLN) and spleens, the mRNA expression of transcription factors and cytokines in Th1 and Treg cells increased and the mRNA expression of Th2 and Th17 transcription factors and cytokines decreased, indicating a regulatory effect on intestinal immune homeostasis. RC-LAB fermented feed regulates gut immune homeostasis by influencing the composition of beneficial and detrimental microorganisms in the gut and regulating the balance of Th1/Th2 and Th17/Treg cells.

• Journal of Korean Library and Information Science Society
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• v.34 no.2
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• pp.143-161
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• 2003

This study intends to analyze the library classification of agriculture in DDC, from the Int edition to the 21th edition. Since Dewey Decimal Classification(DDC) was the first published in 1876, number of total items increased significantly a newly-organized and subdivision of them in the 8th, 10th and 12th edition. According as the discipline developed and was specialized, the agricultural division in DDC was fractionized, and new subjects were continuously added to it. After that time the first edition, the major changes arranged an class and order in the 15th and 17th edition. That is to say, ‘Farm economics’ in 631.1 was relocated to 338.1 in the 17th and ‘Veterinary sciences’ in 619 was relocated to 636.089 in the 15th. Especially, up to now ‘Farm Economics’ deals with an important branch in the science of agriculture. Here the matter of argue heatedly arranges it from economics to agriculture.

• Journal of the Korean Society of Costume
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• v.61 no.2
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• pp.60-71
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• 2011

This study set out to examine Hakchangui worn in Joseon around the 18th century and further the relationships between the Chinese Hakchang and Joseon Hakchangui, as well as to figure out spread factors of Hakchangui. The study proceeded as follows: 1)The Hakchangui was examined those appearing in the collections of works and paintings after the 17th century. 2)The Zhuge Liang's Hakchang was researched through Romance of Three Kingdoms, paintings and sculptures. 3)The images of Hakchangui wearers described in literature were investigated to understand the symbolic meanings of Hakchangui in Joseon those days. Those research efforts revealed four findings: 1)In many cases, the Hakchangui worn in Joseon in the 17th and 18th century has side slits, but no back slit. It's both sides of the center front were parallel, not overlapped. 2)Hakchangui was strange to the Joseon people until the end of the 18th century but started to permeate among those who liked classic style. 3)The aspects of Zhuge Liang were standardized in the combination of 'Yungeon, Hakchang, a feather fan and a wagon' in Romance of Three Kingdoms. 4)Zhuge Liang was considered as a symbol of wisdom and loyalty and had an image of a Taoist hermit who transcended the mundane world. The analysis of the research findings led to two following conclusions: 1)ln Joseon the Chinese Hakchang was introduced to people who had exchanges with Chinese or liked classic style in the 17th and 18th century and gradually spread by their advocates. 2)The Hakchangui must have been increasingly worn by more Joseon scholars because they started to borrow the image of Zhuge Liang driven by the popularity of Romance of the Three Kingdoms and the tendency of reinforcing Zhuge Liang's image as a loyal subject by the kings of Joseon.

• Journal of the Korean Society of Costume
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• v.63 no.8
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• pp.76-89
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• 2013

This study is about 'asymmetry triangle-Mu' Jeoksam and Hansam in the early days of Joseon Dynasty. A study was done regarding the records of Jeoksam and Hansam in literature, the present state of the excavated 'asymmetry triangle-Mu' clothing Jeoksam and Hansam, and finally a deduction of the reason for the appearance of the 'asymmetry triangle-Mu' clothing Jeoksam and Hansam. The width of front length of 'asymmetry triangle-Mu' clothing in the early days of Joseon Dynasty is 29.5~35 cm and the width of one breath of the sleeve is 29.5~35 cm. The width of 'asymmetry triangle-Mu' is 9.5~16 cm and it is relatively big. Comparing to the width of one breath of the sleeve, it is almost 1:2.2~3.6 ratio. Therefore, when the sleeve was cut, the Mu was linked in order to save fabric the gusset of sleeve had to be folded and turned, and finally it became asymmetric. As a result of the above consideration, since the width of upper garments of $16{\sim}17^{th}$ century was big, the wearing of short tops of Jeoksam or Hansam without side vent as a small 'triangle-Mu' was uncomfortable. Because of this reason, the size had no option but to become bigger. So, during the $16^{th}$ and $17^{th}$ century, a period where mass production of fabric was difficult, the 'asymmetry triangle-Mu' type was considered to be a reasonable cutting method. After the middle of $17^{th}$ century, it can be estimated that 'asymmetry triangle-Mu' clothing disappeared according to the narrow aspect of clothing type.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.23 no.1
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• pp.115-124
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• 1993

The purpose of this study was to evaluate the clinical and radiographic features of 35 cases of nasopalatine duct cyst by means of the analysis of periapical and/or occlusal radiograms in 35 persons visited the Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyung Hee University and Chonbuk National University. The obtained results were as follows: 1. The incidence of nasopalatine duct cysts was higher in males(74.3%) than in females(25.7%). 2. The nasopalatine duct cysts were the most frequently occurred in the 4th decades(34.3%). The 6th and 7th decades(17.1%, 17.1%) were next in order to frequency followed by the 5th decades(14.3%), the 3rd decades(8.6%), the 2nd decades(5.7%), and 8th decades(2.9%). 3. In the signs and symptoms of nasoplatine duct cysts, 25.7% were swelling, 17.1% were swelling and tenderness, 20.0% were swelling and pain, and 37.2% were asymptom. 4. In the shape of nasopalatine duct cysts, 40.0% were round type, 48.6% were oval type, and 11.8% were heart type. In symmetry of the nasopalatine duct cysts to the median palatine surture, 85.7% were symmetry, 14.3% were asymmetry. 5. In the width of nasopalatine duct cysts, 11.4% were 6-l0㎜, 48.6% were 11-20㎜, 25.7% were 21-30㎜, and 14.3% were 31-40㎜. 6. In the periphery of nasopalatine duct cysts, 82.9% were distinct, 17.1% were relatively distinct. 7. In the change of root, 51.5% were intact, 17.1% were root divergence, 20.0% were root resorption, and 11.4% were root divergence and resorption.

• The Korean Journal of Pain
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• v.34 no.4
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• pp.463-470
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• 2021

Background: Although neuropathic pain is a severe and common pain, its pathophysiology has not been elucidated yet. Studies in recent years have focused on the immune system's role in the pathogenesis of neuropathic pain. The aim of this study was to investigate the role of immunological mechanisms in neuropathic pain and the effect of pregabalin by measuring immunological marker levels in peripheral blood before and after pregabalin treatment in postherpetic neuralgia (PHN) patients with neuropathic pain. Methods: Forty patients diagnosed with PHN were included in the study. CD4, T follicular cells (Tfh: CD4⁺CXCR5⁺PD1⁺), Th17 (CD4⁺CCR6⁺ and CD4⁺IL17A⁺), regulatory T cells (Treg: CD4⁺ CD25⁺foxp3⁺), Th1 (CD4⁺ CXCR3⁺ and CD4⁺ IFN-γ⁺) and Th2 (CD4⁺ IL-4⁺) cell ratios were measured in peripheral blood samples before treatment and after 3 months of treatment. Results: When immunological marker and inflammation parameter levels were compared before and after treatment, the helper T cell ratio (CD3⁺, CD4⁺) was 30.28 ± 12.27% before treatment and 34.93 ± 11.70% after treatment, so there was a statistically significant increase (P = 0.028). Th17 was 4.75 ± 5.02% before treatment and 5.80 ± 3.13% after treatment, and there was a statistically significant increase (P = 0.036). Conclusions: Immunological mechanisms play an essential role in the pathogenesis of neuropathic pain, immunologically based treatment approach will be the critical point of treatment.