• Title/Summary/Keyword: Th17

Search Result 3,292, Processing Time 0.035 seconds

A Study on Modesty in Western Costume (서양복식에 나타난 정숙성에 관한 연구 -6~12세기와 17세기 청교도 혁명기를 중심으로-)

  • 이희현;김진구
    • The Research Journal of the Costume Culture
    • /
    • v.1 no.2
    • /
    • pp.181-198
    • /
    • 1993
  • The study is to analyze modesty of clothing motive of western costume during the 6∼12 th and 17th pilgrim's revolution period by Flugel's theory. these society of tow period maintained the moral and ascetic life under he control christianity and pilgrim. This study utilized terms of Freud's theory on human personality in defining the characteristics of periods. Two periods is to define as Super-ego period.

  • PDF

Outline of 2001 FIFA World Cup$^{TM}$ (2002년 FIFA World Cup 대회의 개요)

  • 전상백
    • Journal of the Korean Professional Engineers Association
    • /
    • v.34 no.5
    • /
    • pp.10-17
    • /
    • 2001
  • The 17th World Cup Event that raises a storm of excitement ever held in the New Millenium will be started with the opening game In Seoul, Korea, on 31st May,'02 and closed with the final match in Yokohama, Japan on 30th June'02 The 2002, FIFA World Cup held In Asian region for the first time in FIFA history is jointly-organized by Korea and Japan. Both Korea and Japan will host each 32 games at the chosen ten local venues in each countries Partierpants from 32 regional countries included host countries Korea and Japan as well as the previous Champion France are scheduled to match one another by tournament method

  • PDF

GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells

  • Jeonghyeon Moon;Seung Hoon Lee;Seon-yeong Lee;Jaeyoon Ryu;Jooyeon Jhun;JeongWon Choi;Gyoung Nyun Kim;Sangho Roh;Sung-Hwan Park;Mi-La Cho
    • IMMUNE NETWORK
    • /
    • v.20 no.5
    • /
    • pp.40.1-40.15
    • /
    • 2020
  • The protein encoded by the Gene Associated with Retinoid-Interferon-Induced Mortality-19 (GRIM-19) is located in the mitochondrial inner membrane and is homologous to the NADH dehydrogenase 1-alpha subcomplex subunit 13 of the electron transport chain. Multiple sclerosis (MS) is a demyelinating disease that damages the brain and spinal cord. Although both the cause and mechanism of MS progression remain unclear, it is accepted that an immune disorder is involved. We explored whether GRIM-19 ameliorated MS by increasing the levels of inflammatory cytokines and immune cells; we used a mouse model of experimental autoimmune encephalomyelitis (EAE) to this end. Six-to-eight-week-old male C57BL/6, IFNγ-knockout (KO), and GRIM-19 transgenic mice were used; EAE was induced in all strains. A GRIM-19 overexpression vector (GRIM19 OVN) was electrophoretically injected intravenously. The levels of Th1 and Th17 cells were measured via flow cytometry, immunofluorescence, and immunohistochemical analysis. IL-17A and IFNγ expression levels were assessed via ELISA and quantitative PCR. IL-17A expression decreased and IFNγ expression increased in EAE mice that received injections of the GRIM-19 OVN. GRIM19 transgenic mice expressed more IFNγ than did wild-type mice; this inhibited EAE development. However, the effect of GRIM-19 overexpression on the EAE of IFNγ-KO mice did not differ from that of the empty vector. GRIM-19 expression was therapeutic for EAE mice, elevating the IFNγ level. GRIM-19 regulated the Th17/Treg cell balance.

Comparison with the 6th and 7th Science Curricular for Inquiry Skill Elements in the Elementary and Secondary School (초.중.고등학교 탐구 기능 요소에 대한 6차와 7차 과학 교육 과정의 비교)

  • Ha, So-Hyun;Kwack, Dae-Oh;Sung, Min-Wung
    • Journal of The Korean Association For Science Education
    • /
    • v.21 no.1
    • /
    • pp.102-113
    • /
    • 2001
  • In order to compare with the 6th and 7th science curricular for the inquiry skill elements in the elementary and secondary school, we divided skill domains into five classes which were process skill, step skill for inquiry instruction, inquiry activity skill, manipulative skill and breeding-farming skill. And then we investigated the kinds and frequencies for the inquiry skill elements of the 6th and 7th curricular in the elementary and secondary school. The results were as follows: 1. The total kinds of inquiry skill element showed 17 kinds in the 6th curriculum and 23 kinds in the 7th. Therefore, the 7th curriculum was higher 1.4 times than the 6th curriculum in the kinds of skill elements. 2. The total frequencies for the inquiry skill elements of the 6th curriculum were 408 and those of the 7th were 729. Therefore, the 7th curriculum was about 1.8 times as many as the 6th. 3. In the kinds of inquiry skill elements according to the school levels, the course of the elementary school showed 14 kinds in the 6th curriculum and 18 kinds in the 7th. The course of middle school showed 7 kinds in 6th and 16 kinds in 7th. The integrated science course of high school was 10 kinds in the 6th and 10 kinds in the 7th. The skill elements in four science curricular of the high school course showed total 11 kinds in the 6th and 21 kinds in the 7th. And then the kinds of inquiry skill elements of the 7th curriculum in the middle and high school course showed about 2 times as many as the 6th curriculum. In the school level, the increase of skill elements showed the highest in the middle school course, and then in the high school course. 4. The total skill elements from the elementary school to the high school in the 6th science curriculum showed 17 kinds and in the order from the highest to the lowest rates, such as experimenting 20%, observing 15%, interpreting and analyzing data 13%, investigating 9%, measuring 7%, drawing a conclusion and assessment 7%, discussion 6%, communicating 5%, classifying 4%, recognizing problems and formulating hypothesis 4%, predicting 3%, designing and carrying out an experiment 3%, collecting and treating data 2%, manipulating skill 1%, modeling 0.5%, breeding and farming 0.3% and inferring 0.2%. 5. The total skill elements from the elementary school to the high school in the 7th curriculum appeared 23 kinds and in the order from the highest to the lowest rates, such as drawing a conclusion and assessment 31%, investigating 14%, collecting and treating data 8%, observing 7%, experimenting 7%, recognizing problems and formulating hypothesis 6%, interpreting and analyzing data 4%, measuring 3%, discussion 3%, manipulating skill 3%, modeling 3%, classifying 2%, project 2%, educational visits 1%, controlling variables 1%, predicting 1%, inferring 1%, operational definition 1%, communicating 1%, designing and carrying out an experiment 0.3%, breeding and farming 0.3%, applicating a number 0.2% and relating with time and space 0.2%. In the conclusion, the 7th curriculum was added 6 kinds of skill elements to the 6th curriculum, such as operational definition, applicating a number, relating with time and space, controlling variables, educational visits and project.

  • PDF

The Role of Thymic Stromal Lymphopoietin (TSLP) in Glomerulonephritis

  • Lee, Keum Hwa;Yang, Jae Won;Cho, Jin Young;Lee, Joo Yup;Lim, Eun Kyung;Eisenhut, Michael;Jeong, Dong Yeon;Steingroever, Johanna;Shin, Jae Il
    • Childhood Kidney Diseases
    • /
    • v.22 no.1
    • /
    • pp.17-21
    • /
    • 2018
  • Thymic stromal lymphopoietin (TSLP) is an interleukin-7-like cytokine that is an important trigger and initiator of many allergic diseases. TSLP promotes a T-helper type 2 (Th2) cytokine response that can be pathological. A relationship is formed both at the induction phase of the Th2 response through polarization of dendritic cells to drive Th2 cell differentiation and at the effector phase of the response, by promoting the expansion of activated T cells and their secretion of Th2 cytokines and TSLP. In transgenic mice with TSLP overexpression, it has been reported that TSLP leads to the development of mixed cryoglobulinemic membranoproliferative glomerulonephritis. In addition, TSLP can play an important role in the pathogenesis of IgA nephropathy and systemic lupus erythematosus-related nephritis. From our knowledge of the role of TSLP in the kidney, further studies including the discovery of new therapies need to be considered based on the relationship between TSLP and glomerulonephritis.

A Study on the Design of an Underwater Distributed Sensor Network for the Shallow Water by An Effectiveness Analysis (효과도 분석을 통한 천해용 수중분산 센서망 설계 연구)

  • Kim, Wan-Jin;Bae, Ho Seuk;Kim, Woo Shik;Lee, Sang Kug;Choi, Sang Moon
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.17 no.5
    • /
    • pp.591-603
    • /
    • 2014
  • In this paper, we have described the characteristics of the Underwater Distributed Sensor Network (UDSN) and proposed the conceptual design guideline by an effectiveness analysis. To perform the effectiveness analysis, we defined an battlefield environment, and then analyzed principal components which compose the UDSN to find out simulation parameters and system constraints. We have chosen a measure of effectiveness based on a target trajectory, which could enhance intuitive understanding about current status, and performed various simulations to reveal critical design parameters in terms of sensor node types, arrangement, cost and combination of detection information.

A Study on the Trend of an Avionics System Architecture Development for UAV (무인기 항공전자 체계의 아키텍처 개발 동향연구)

  • Kim, Sung Woo;Sim, Jae Ick;Lee, Wang Gug;Lee, Woo Jin;Won, Dae Yeon
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.17 no.4
    • /
    • pp.436-447
    • /
    • 2014
  • The major elements of avionics system architecture are requirements, Real Time Operating System, message communication, memory, and data format etc. Herein describes a state-of-the-art development trend for the avionics system architecture, system requirements and data bus among the major elements of avionics system. While, domestic technology has been tried to Integrated Modular Avionics(IMA) system based on the Avionics Full Duplex Switched Ethernet(AFDX) technology during Light Attack Helicopter(LAH) project in Korea, but not yet proved as the product case in Full Scale Development Phase. The avionics system architecture considering the domestic inexperience of the IMA system architecture are suggested for the Next-generation Corps Unmanned Aircraft System.

Effects of Raising Seeding by Cold Water, Low Night Temperature, and Using Abandoned Mine on Flower Bud Differentiation, Growth and Yield of Forcing Cultured Strawberry (Fragaria x ananassa Duch.) (냉수경, 야냉 및 폐광육묘가 촉성딸기의 화아분화와 생육 및 수량에 미치는 영향)

  • Kim, Woon-Seop;Yoon, Wha-Mo
    • The Journal of Natural Sciences
    • /
    • v.8 no.1
    • /
    • pp.71-80
    • /
    • 1995
  • This experiment was conducted to investigate the effect of raising seedling methods of cold water, low night temperature, and abandoned mine on forcing culture of strawberry. The results were as follows ;1. $17^{\circ}C$ cold water alone and cold water plus 8-hour short day treatments significantly accelerated the flower bud differentiation of Nyoho cultivar to 11 and 15 days, respectively, comparing to common soil raising seedling.2. The date of flower bud differentiation of Nyoho cultivar as influenced by cold water treatment the 17th, the 13th and the 10th of September, respectively, when the seedlings were treated on the 10th of September and on the 25th and the 10th of August in 1991. In 1992, data showed that the flower bud differentiation dates were the 4th and the 2nd of September and the 29th of August when cold water treatment was done on the 10th of August and on the 25th and the 10th of July.3. The first harvest date when Nyoho cultivar was treated by cold water for 30days from Jul. 25 was Nov. 10, this implying that the harvesting day could advanced to 19 days comparing to that by the common soil raising seedling method. The resulting yield was recorded to 21.94 ton per hectare.4. Regardless of the starting date of the treatment, $13^{\circ}C$ low night temperature plus 8-plus short day treatments for 20 days required 17 days to differentiate the flower bud of Nyoho cultivar. Harvesting day could be advanced to 59 days comparing to that by the common raising seedling method when the seedling was treated on July 25, this resulting in increasing the total yield obtained by April 14 of following year to 8.25 ton per hectare.5. When the seedlings of both Nyoho and Hokowase cultivars were raised under the condition of abandoned mine, flowering and harvest date were earlier by the treatment for 20 days than that for 30 days or 40 days. The highest yiesd obtained was recorded in Nyoho cultivar or 1.88 ton per hectare.

  • PDF

The Moksoo-Pyunsoo of the 17th Century Palace Building Constructions of the Chosun Dynasty (조선조 17세기 궁궐건축공사에 종사한 목수편수에 대하여)

  • Kim, Dong-Uk
    • Journal of architectural history
    • /
    • v.1 no.1 s.1
    • /
    • pp.9-17
    • /
    • 1992
  • According to the 17th century palace construction documents, head artisans were called Pyunsoo. In one building constructions, not only carpenters but also masons, plasterers and painters had their own head, Pyunsoos. This meant that Moksoo-Pyunsoo, head carpenter, could not manage the whole design of the building. Moreover, in many cases, selecting and laying the site of the building were determined by the geomancers. Under those working conditions, Moksoo-Pyunsoo could only have charge of designing the wooden parts, such as structural forms or detailed carvings. The documents showed that some dominent carpenters, like Kwak Ki Jong or Lee Choon Bong, had taken on the post of Moksoo-Pyunsoo in almost every palace constructions, especially inner palace buildings. Form the fact that the same carpenters had worked continuosly, it can be presumed that there would have many resemblance of structural forms or carvings among those inner palace buildings.

  • PDF

Daily and Monthly Death Pattern an Intentional Self-harm by Hanging, Strangulation and Suffocation in Korea, 2011 (일별, 월별 의도적 자해의 사망 양상에 관한 연구: 2011 인구동태동계자료 중심으로)

  • Park, Sang Hwa;Lim, Dar Oh
    • Health Policy and Management
    • /
    • v.23 no.3
    • /
    • pp.260-265
    • /
    • 2013
  • Background: The aim of this study was to examine the seasonal variation of death from intentional self-harm by hanging, strangulation and suffocation (HSS: Korean Standard Classification of Diseases-6 code: X70) using the 2011 death registry data. Methods: The analysis was based on data of 8,359 HSS deaths from 2011 national vital statistics in Korea. Daily, weekly, and monthly death pattern on HSS were used to examine the relationship seasonal variation and HSS deaths. Results: A total of 8,359 HSS deaths occurred in 2011, with a mean age of 50.6 years. The HSS death rate (per 100,000) was 25.5 in male and 10.8 in female. In one day 17.6 males and 8.0 females occurred HSS death on average. The number of HSS death per day was the highest on 8th June (45 deaths), and lowest on 1st February (7 deaths) during the period. The variations of daily HSS death showed wide fluctuation from a peak of 34 to 45 deaths (29th May to 9th June) to a trough of 17-26 deaths (10th-13th September: the Korean thank-giving consecutive holidays), 13-20 deaths (2nd-5th February: the new year's day by the lunar calendar) and 8-9 deaths (24th-25th December: Christmas holidays). There were no significant difference between gender and seasonal variation (month, season, and week). Conclusion: The mean number of HSS death per day was highest in June (30.6 deaths), and months with the lowest number of deaths was January and December (range, 19.4 to 19.6 deaths). HSS death were more prevalent during summer and spring and were less likely to occur during winter. On Saturdays (21.0 deaths), the number of HSS death per day was the lowest, and Monday (27.9 deaths) was the highest. HSS death was less likely to occur on holidays (21.4 deaths). There was significant seasonal variation in HSS death by weekly and monthly (p<0.01).