• The Journal of Internal Korean Medicine
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• v.30 no.3
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• pp.451-464
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• 2009

Background and Objective : Cyperus rotundus L. (CR) is a commonly used herbal medicine in Asian countries such as Korea, China and Japan. The present study was designated to evaluate the direct effects of CR on helper T cell activities and on Th1/Th2 lineage development in vitro. Materials and Methods : Spleen cells from 8 week BALB/c mice were cultured in CR extracts containing medium without activation for 24 hours and with activation for 48 hours. CD4+ T cells were isolated and analyzed for mRNA expression levels of INF-$\gamma$, IL-4, T-bet and GATA-3 by RT-PCR and secretion cytokines levels of INF-$\gamma$, IL-4, IL-5 and IL-10 by ELISA. Results : The results demonstrated that CR had no mitogenic effects on unstimulated CD4+ T cells, but augmented CD4+ T-cell proliferation upon activation with anti-CD3/anti-CD28 antibodies in a dose-dependent manner. CR treatment significantly increased CD4+ T cell population and the IFN-$\gamma$ expression was significantly enhanced, while IL-4 expression was significantly decreased. In addition, in vitro Th1/Th2 polarization experiments revealed that CR enhanced IFN-$\gamma$ secretion in Th1 cells, but reduced the IL-4 in Th2 cells in a dose-dependent manner. Conclusion : These results suggest that CR treatment could be a desirable alternative therapy for the prevention or correction of Th2 dominant pathological disorders, such as allergy and asthma.

• Korean Journal of Health Education and Promotion
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• v.13 no.2
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• pp.35-53
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• 1996

The objective of the health promotion program was to strengthen the ability and willingness of individuals in the course of each stage of their lives to take action in support of their health and that of their families and communities in the home, the place of work and the school, and during recreation. The purpose of this study was to assess the need of school health promotion through health care behavior survey about diet, accident prevention, cigarette smoking experience, personal hygiene, visual impairment prevention, exercise, and environment protection. The subjects of this study were 914 students composed of Samrye, Bongdong, Samrye-Dong, Iseo, and Songkwang elementary school in Wanju area. The data were collected by questionaire corrected for the purpose of this study which had been developed by WHO, ‘Health behavior in school children’. These were carried out from March 20 to April 20, 1996. The data was analyzed by frequency, percentage, χ²-test with SPSS-PC+ program. The results were as follows. 1. Diet related behavior 1) Girl students eat less breakfast than male students. 2) Girl students eat less 3 times a day than male students. 3) The rate of eating nutritious medicine was high in order of 4th, 6th, and 5th graders. 4) Girl students drink less milk than male students. 5) The intake frequency of eating between meals was high in order of 6th, 5th, and 4th grader. 2. Cigarette smoking behavior 1) The rate of cigarette smoking rarely was high in 5th grader. 2) Male students smoke cigarette more than girl students. 3. Personal hygiene related behavior 1) The rate of washing hands after using toilet room was low in order of 4th, 5th, and 6th graders. 2) The rate of washing hands after using toilet room was low in male students. 3) The rate of washing hands when entering home from outdoor was low in male students. 4) The tooth brushing frequency before going to bed was low in male students. 5) The tooth brushing frequency was low in male students. 6) The rate of bathing was most low in 4th grader. 7) The rate of bathing was low in male students. 4. Visual impairment preventive behavior 1) The distance between eyes and book was near in order of 6th, 5th, and 4th graders. 5. Exercise 1) The exercise time in school was less in 4th grader. 2) The exercise time in school was less in girl students. 3) The exercise time out of school was less in 4th grader. 4) The exercise time out of school was less in girl students. 5) The self evaluation score about exercise ability was low in girl students. 6. Environment related behavior D The rate of collecting waste separately in school was most low in 4th grader.

• The Journal of Korean Medicine
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• v.30 no.3
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• pp.15-27
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• 2009

Objective : This study was carried to identify the anatomical component of BMM (Foot Taeyang Meridian Muscle in the human truncus), and further to help the accurate application to real acupunctuation. Methods: The human truncus was stripped off in order to demonstrate muscles, nerves and other components, and to display the internal structure of the BMM, dividing into outer, middle, and inner parts. Results: The BMM in the human truncus is composed of muscles, nerves, ligaments etc. The internal composition of the BMM in the human truncus is as follows: 1. Muscle A. Outer layer: medial palpebral ligament, orbicularis oculi, frontalis, galea aponeurotica, occipitalis, trapezius, latissimus dorsi, thoracolumbar fascia, gluteus maximus. B. Middle layer: frontalis, semispinalis capitis, rhomboideus minor, serratus posterior superior, splenius cervicis, rhomboideus major, latissimus dorsi, serratus posterior inferior, levator ani. C. Inner layer: medial rectus, superior oblique, rectus capitis, spinalis, rotatores thoracis, longissimus, longissimus muscle tendon, longissimus muscle tendon, multifidus, rotatores lumbaris, lateral intertransversi, iliolumbaris, posterior sacroiliac ligament, iliocostalis, sacrotuberous ligament, sacrospinous ligament. 2. Nerve A. Outer layer: infratrochlear nerve, supraorbital n., supratrochlear n., temporal branch of facial n., auriculotemporal n., branch of greater occipital n., 3rd occipital n., dorsal ramus of 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 8th, 9th, 10th, 11th, 12th thoracic n., dorsal ramus of 1st, 2nd, 3rd, 4th, 5th lumbar n., dorsal ramus of 1st, 2nd, 3rd, 4th, 5th sacral n. B. Middle layer: accessory nerve, anicoccygeal n. C. Inner layer: branch of ophthalmic nerve, trochlear n., greater occipital n., coccygeal n., Conclusions : This study shows that BMM is composed of the muscle and the related nerves and there are some differences from already established studies from the viewpoint of constituent elements of BMM at the truncus, and also in aspect of substantial assay method. In human anatomy, there are some conceptional differences between terms (that is, nerves which control muscles of BMM and those which pass near by BMM).

• Journal of Fashion Business
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• v.16 no.1
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• pp.16-25
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• 2012

As the test results for surface color, dyeing durability, antibiosis of cotton fabrics and silk fabrics dyed with Agastache rugosa extract, the following conclusions were obtained. The surface color of all the dyed fabrics was confirmed mostly as a GY system. As the result of chrominance(${\Delta}E_{ab}$) measurement, in the case of cotton fabrics the dyed fabrics treated with $Al_2(SO_4)_3$ mordant showed the highest value and in the case of silk fabrics the non-mordant dyed fabrics showed the highest value. The dyeing durability of test fabrics dyed with Agastache rugosa extract are as follows. As the test results of colorfastness to laundry for cotton dyed fabrics, the discoloration degree showed 1st-2nd grade and the contamination degree showed 4th-5th grade. As the test result of colorfastness to dry cleaning for silk dyed fabrics, the contamination degree showed from 1st to 3rd-4th grade. As the test results of colorfastness to acid artificial perspiration, the discoloration degree showed from 1st to 3rd-4th grade and the contamination degree showed from 3rd to 4th-5th grade. As the test results of colorfastness to alkaline artificial perspiration, the discoloration degree showed from 1st to 4th grade and the contamination degree showed from 3rd to 4th-5th grade. The colorfastness to sunlight showed from 1st to 2nd grade. The colorfastness to rubbing showed from 3rd to 4th-5th grade in dry process and from 2nd-3rd to 4th-5th grade in wet process. As the test results of antibiosis, the decrease rate of germs to virus Klebsiella pneumoniae and Staphylococcus aureus showed at least more than 99% after the wash of 10 times. As the test results of antifungal activity to mycete Trichophyton mentagrophytes and Aspergillus niger, the both cotton and silk dyed fabrics didn't gain the significant antifungal effect.

• Proceedings of the PSK Conference
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• 2003.10a
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• pp.62-63
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• 2003

The commitment of T helper (Th) cells to Thl or Th2 cells is of crucial importance with respective to susceptibility or resistance to particular infections, or to autoimmune diseases and allergic diseases. The nature of Thl or Th2 polarizing signals is not yet fully understood. However, the cytokines that are present in the environment of the $CD4^{+}$ T cell at the time it encounters the antigen significantly regulate the differentiation of Th cells into either Thl or Th2 subsets. (omitted)

• The Transactions of The Korean Institute of Electrical Engineers
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• v.61 no.10
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• pp.1554-1560
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• 2012

In this paper, the even harmonic current(2nd, 4th, 6th, 8th) of the arc fault current and normal current were measured in computer load and analyzed. The BPF with GIC was developed to detection of harmonic, the exact center frequency and a high degree of sharpness could be easily obtained. The total even harmonic distortion due to series arc fault in computer load was 31.2%, this value was increased 3.9 times better than the total even harmonic distortion of normal current. The results of analysis of arc fault current RMS variation rate and Peak variation rate per half-cycle, The RMS average variation rate are as follows ; the 2nd harmonic was 0.24, the 4th harmonic was 0.15, the 6th harmonic was 0.19, the 8th harmonic was 0.25, respectively. The Peak average variation rate are as follows ; the 2nd harmonic was 0.19, the 4th harmonic was 0.12, the 6th harmonic was 0.13, the 8th harmonic was 0.15, respectively. The results of this analysis utilize data to detect of series arc fault on wiring of computer load.

• Journal of Microbiology and Biotechnology
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• v.17 no.12
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• pp.2056-2060
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• 2007

Transcription factor GATA-3 is the critical transcription factor for Th2 cell differentiation. In spite of its importance in Th2 cell differentiation, the molecular mechanism for its action in Th2 differentiation is poorly understood. Previous studies have suggested that GATA-3 may be involved in the chromatin remodeling in the Th2 cytokine locus. To determine whether GATA-3 exerts its effect on its target sites in the extrachromosomal status, cell transfection assay was performed. In this assay, 800 bp IL4 promoter-luciferase constructs linked with GATA-3 target sites were transfected into the M12 B cell line, D10 mouse Th2 cell lines, and human T lymphoma Jurkat cell lines with or without the GATA-3 expression vector. The GATA-3 effects on its target sites were minimal in the extrachromosomal status, supporting the previous propositions that GATA-3 functions at the chromatin level by remodeling chromatin structure.

• Journal of Veterinary Clinics
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• v.22 no.1
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• pp.43-49
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• 2005

The aim of this study is to investigate the wound healing effects of the Opuntia ficus-indica. Four full-thickness skin wounds(2.5 cm × 2.5 cm) were made in different areas on the back in each of five dogs. Two wounds were used for wound size measurement and two for skin biopsy. The ten full-thickness wounds were treated with the extract of Opuntia ficus-indica, and the ten full-thickness wounds were treated with normal saline. The wound areas were measured every other day for three weeks after wounding. Statistical analysis was performed with the paired t-test. The wound healing rates were 32.9±4.0%, 28.2±7.1%, 42.2±4.1%, 55.0±4.3%, 76.6±2.8%, 86.8±2.3%, 94.0±1.l%, 97.3±0.8%, 99.3±0.3%, 99.8±0.2%, 100.0±0.0% in the experimental group, and 18.0± 8.2%, 13.S± 11.6%, 15.2±6.1 %, 36.9±8.8%, 62.4±4.1%, 80.0±2.3%, 86.0±1.4%, 94.0±0.9%, 96.9±0.8%, 97.8±0.3%, 99.7±0.1% in the control group on the 1/sup st/, 3/sup rd/, 5/sup th/, 7/sup th/, 9/sup th/, 11/sup th/, 13/sup th/, 15/sup th/, 17/sup th/, 19/sup th/, 21/sup st/ day. On the 17/sup th/ day, the wound closed above 99.9% in 1 dog of the experimental group. On the 19/sup th/ day, the wound closed above 99.9% in 3 dogs of the experimental group. On the 21/sup st/ day, the wound closed above 99.9% in 5 dogs of the experimental group, and 1 dog of the control group. The wound healing period was shortened by 2 to 4 days in the experimental group as compared with the control group. The tensile strength was 4,508±513 g/㎠ in the experimental group and 2,772±400 g/㎠ in the control group on the 21/sup st/ day after wounding. The tensile strength was significantly higher in the experimental group than in the control group(p< 0.05). Inflammation rapidly spread and disappeared in the experimental group but not in the control group. Fibroblast and vascularization were found on the 5/sup th/ day in both group and increased only in the experimental group on the 9/sup th/ day. The firs finding of epithelialization was on the 13/sup th/ day in the experimental group and the 21/sup st/ day in the control group. A significantly higher wound healing rate(p< 0.05), tensile strength(p< 0.05) and better histopathological findings were observed in the experimental group than in the control group throughout the experimental period. These results suggest that topical application of Opuntia ficus-indica extract can promote wound healing in dogs.

• Journal of Nutrition and Health
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• v.22 no.1
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• pp.36-41
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• 1989

In this study longitudinal of the taurine content in the human milk of 23 Korean lacto-ovo-vegetarian women was studied during the lactating periods of the 15th, 30th, 60th, 90th, 120th and 150th day after delivery. The results of the study on primiparae and multiparae studied separately are as follows: 1) The taurine content of the primiparae per 1ml of human milk was 356.1nmole on the 15th day, 238.6 nmole on the 30th day, 249.6 nmole on the 60th day, 148.7 nmole on the 20th day, and 139.6 nmole on the 150th day. There was a significant decrease in the measns. 2) The taurine content of the multiparae per 1ml f human milk was 401.6 nmole on the 90th day, 189.9 nmole on the 120th day, and 159.8 nmole on the 150th day. There was a significant decrease in the measns. 2) The taurine content of the multiparae per 1ml of human milk was 401.6 nmole on the 15th day, 342.3 nmole on the 30th day, 273.2 nmole on the 60th day, 248.6 nmole on the 90th day, 189.9 nmole on the 120th day, and 159.8 nmole on the 150th day. There was a significant decrease in the measns. The multipareas had higher taurine content in every lactating period than the primiparae but there was not a significant difference. The correlation between the changes durinig lactating periods and the taurine content was negative. The correlation coefficient of the primiparae was -0.641 and that of the multiparae was -0.753. The overall correlation coefficient of the primiparae and the multiparae is -0.644, decreasing significantly up to the 150th day.

• Journal of Genetic Medicine
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• v.4 no.2
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• pp.179-185
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• 2007

Purpose : Catecholamines are the neuro-transmitters in the sympathetic nervous system (SNS) and are activated by stress stimulus. Tyrosine hydroxylase (TH) and Dopamine-${\beta}$-Hydroxylase (DBH) are very important enzymes in the catecholamine synthesis. Corticotropin releasing hormone (CRH) is released in the process of reacting to stresses. The aim of this study is to find out what effects immobilization stresses have on the expression of TH, BDH and CRH mRNA in a rat's brains. Methods : We compare expression levels in rat's brains of TH, DBH and CRH mRNA induced by immobilization stresses between the test group and controled group. The expression levels of TH, DBH and CRH mRNA are measured by RT-PCR and the Western Blotting Analysis (WBA). Results : In brains and adrenal glands of the immobilization stress group, the expression levels of TH and DBH mRNAs are significantly two to three times higher (P<0.01), and CRH mRNAs are approximately one and a half times higher (P<0.05) than those of controlled group. Conclusion : This study suggest that the expression levels of TH, DBH and CRH mRNAs are activated by stress stimulus in a rat's brains and adrenal glands.