• 한국항공운항학회지
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• 제15권4호
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• pp.9-16
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• 2007

Tilt rotor aircraft can take off and land vertically and cruise faster than any other helicopter. A scaled flight demonstration model of a tilt rotor aircraft has been developed by KARI. Because the flight characteristics of tilt rotor are not well known, the developed scaled model would be helpful to evaluate flight control algorithm of a full scale aircraft. The tethered hover test has been performed in order to improve hover flight characteristics of tilt rotor aircraft prior to flight test of the small scaled model. During the tethered hover test, the performance of rotor speed governor, rate SAS (Stability Augmentation System) and control surface mixers have been evaluated. We expect that the results of real flight hover test would be quite same as tethered hover test. Therefore the tethered hover test results will reduce the risk of flight test properly by fixing some of hidden problems which might occur during the flight test. This paper presents the results of tethered hover test in detail and shows how it could be final ground test before flight test. The control mixer gain and rate SAS feedback gains were modified in order to get higher controllability and stability during the tethered hover flight. The rotor governor showed that it could keep rotor RPM constant with very small deviation even during severe pilot collective input change. The tethered hover test results gave pilot and engineers confirmation and experience about the scheduled flight test.

• Asian-Australasian Journal of Animal Sciences
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• 제21권9호
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• pp.1252-1261
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• 2008

Twenty-four yearling Boer$\times$Spanish goats were used in a crossover design experiment to determine effects of tethering on forage selection, intake and digestibility, grazing behavior and energy expenditure (EE) with forage high in nutritive value and low to moderate in mass. Objectives were to determine if tethered goats could be used as a model for study of unrestrained animals and to characterize tethering as a production practice. Four 0.72-ha pastures of wheat (Triticum aestivum) and berseem clover (Trifolium alexandrium) were grazed in December and January. Each pasture hosted six animals, three with free movement and three attached to a 4.11-m tether for access to a circular area of $53.1m^2$. Tethering areas were moved each day. One animal of each treatment and pasture was used to determine forage selection, fecal output or grazing behavior and EE; therefore, there were eight observations per treatment. Mass of forage DM before grazing in Tethered areas averaged 1,280 and 1,130 kg/ha in periods 1 and 2, respectively. The CP concentration in ingesta was greater ((p<0.05) 239 and 209 g/kg; SE = 8.0) and the NDF level was lower (p<0.05) for Free vs. Tethered animals (503 and 538 g/kg; SE = 12.0); in vitro true DM digestion was similar between treatments (0.808 and 0.807 for Free and Tethered, respectively; SE = 0.0096). Intakes of DM (1,013 and 968 g/d; SE = 78.6), NDF (511 and 521 g/d; SE = 39.9) and ME (10.9 and 10.7 MJ/d; SE = 0.90) were similar between treatments, but CP intake was greater (p<0.05) for Free vs. Tethered animals (241 and 203 g/d; SE = 17.2). There were small treatment differences in in vivo apparent digestibility of OM ((p<0.05) 0.780 and 0.814; SE = 0.0049), CP ((p<0.05) 0.800 and 0.817; SE = 0.0067) and NDF ((p<0.09) 0.777 and 0.760 for Free and Tethered, respectively; SE = 0.0078). There were no treatment effects on time spent ruminating or grazing (346 and 347 min/d for Free and Tethered, respectively; SE = 42.5), but EE was considerably greater (p<0.05) for Free vs. Tethered animals (571 and 489 kJ/kg $BW^{0.75}$; SE = 8.9). In conclusion, with forage of high nutritive value and low to moderate in mass, tethering can offer a production advantage over free grazing of less energy used for activity despite similar grazing time. With forage removal considerably less than that available for grazing, effects of tethering on chemical composition of selected forage were small and less than needed to markedly affect digestion. Tethering may offer a means of studying some aspects of grazing by ruminants, but would not seem suitable for energy metabolism.

• Korea-Australia Rheology Journal
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• 제19권3호
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• pp.141-146
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• 2007

We examine the wall contact of a $3\;{\mu}m$ tethered DNA chain's free end under shear with a focus on developing schemes for double-tethering in the application of making scaffolds for molecular wires. At this scale our results are found to be highly dependent on small length scale rigidity. Chain-end-wall contact frequency, mean fractional extension deficit upon contact, and standard deviation in extension upon contact are examined for scaling with dimensionless flow strength, Wi. Predictions made using a one dimensional approximation to the Smoluchowski equation for a dumbbell and three dimensional dumbbell simulations produce extension deficit, standard deviation, and frequency scaling exponents of -1/3, -1/3, and 2/3, respectively whereas more fine-grained Kratky-Porod (KP) simulations produce scaling exponents of -0.48, -0.42, and 0.76. The contact frequency scaling of 2/3 is derived from the known results regarding cyclic dynamics Analytical scaling predictions are in agreement with those previously proposed for ${\lambda}-DNA$. [Ladoux and Doyle, 2000, Doyle et al., 2000]. Our results suggest that the differences between the dumbbell and the KP model are associated with the addition of chain discretization and the correct bending potential in the latter. These scaling results will aide future exploration in double tethering of DNA to a surface.

• 수산해양기술연구
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• 제53권2호
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• pp.152-159
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• 2017

Rockfish was a commercially important fish specie in marine ranching areas in Korea. To estimate density and biomass of rockfish using acoustic method, target strength (TS) information is required on the species. This study measured TS dependence on tilt angle and size on 14 live rockfish individuals at 38, 70, and, 120 kHz by ex-situ measurement (tethered method) and acoustic scattering model (Krichhoff ray mode, KRM). The swimbladdered angle ranged from 18 to $30^{\circ}$ ($mean{\pm}s.d.=26{\pm}4^{\circ}$). The mean TS for all individuals was highest -35.9 dB of tilt angle $-17^{\circ}$ at 38 kHz, -35.4 dB of tilt angle $-25^{\circ}$ at 70 kHz, and -34.9 dB of tilt angle $-22^{\circ}$ at 120 kHz. The ex-situ TS-total length (TL, cm) relationships were $TS_{38kHz}=20log_{10}(TL)-67.1$, $TS_{70kHz}=20log_{10}(TL)-68.6$, and $TS_{120kHz}=20log_{10}(TL)-69.9$, respectively. The model TS-total length (TL, cm) relationships were $TS_{38kHz}=20log_{10}(TL)-66.4$, $TS_{70kHz}=20log_{10}(TL)-67.0$, $TS_{120kHz}=20log_{10}(TL)-67.0$. The two measurements between the ex-situ TS and KRM model for TS-tilt angle and fish size were found to be significantly correlated.

• Bulletin of the Korean Chemical Society
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• 제27권3호
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• pp.381-385
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• 2006

The temperature dependence on the electron transfer rate constant $(k_{app})$ for hydroquinone redox center in $H_2Q(CH_2)_n$SH-SAMs (n = 1, 4, 6, 8, 10, and 12) on gold electrode was investigated to obtain reorganization energy $(\lambda)$ using Laviron’s formalism and Arrhenius plot of ln $[k_{app}/T^{1/2}]$ vs. T^{-1} based on the Marcus densityof-states model. All the symmetry factors measured for the SAMs were relatively close to unity and rarely varied to temperature change as expected. The electron tunneling constant $(\beta)$ determined from the dependence of the $k_{app}$ on the distance between the redox center and the electrode surface gives almost the same $\beta$ values which are quite insensitive to temperature change. Good linear relationship of Arrhenius plot for all $H_2Q(CH_2)_n$SH-SAMs on gold electrode was obtained in the temperature range from 273 to 328 K. The slopes n Arrhenius plot deduced that $\lambda$ of hydroquinone moiety is ca. 1.3-1.4 eV irrespectively of alkyl chain length of the electroactive SAM.

• BMB Reports
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• 제51권12호
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• pp.623-629
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• 2018

For mechanical force to induce changes in cellular behaviors, two main processes are inevitable; perception of the force and response to it. Perception of mechanical force by cells, or mechanosensing, requires mechanical force-induced conformational changes in mechanosensors. For this, at least one end of the mechanosensors should be anchored to relatively fixed structures, such as extracellular matrices or the cytoskeletons, while the other end should be pulled along the direction of the mechanical force. Alternatively, mechanosensors may be positioned in lipid bilayers, so that conformational changes in the embedded sensors can be induced by mechanical force-driven tension in the lipid bilayer. Responses to mechanical force by cells, or mechanotransduction, require translation of such mechanical force-induced conformational changes into biochemical signaling. For this, protein-protein interactions or enzymatic activities of mechanosensors should be modulated in response to force-induced structural changes. In the last decade, several molecules that met the required criteria of mechanosensors have been identified and proven to directly sense mechanical force. The present review introduces examples of such mechanosensors and summarizes their mechanisms of action.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.176.2-176.2
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• 2003

Transcription factors (TF) can bind tightly to specific DNA lesions formed by some anticancer agents. The formation these TF:(drug-modified DNA) complex may disrupt expression of genes critical for cell survival, and it was proved to be one of biochemical mechanisms of anticancer activity. Based on this model, we have designed programmable DNA Alkylating agents that can also attract TF, especially nuclear receptors. As a model compound, we designed drug molecules, RA-mustard and Am580-mustard, that enable to bind both retinoic acid receptor (RAR) and DNA by using molecular modeling techniques, and synthesized them by connecting chlorambucil and ligand for RAR with a linker unit. (omitted)

• Asian Journal of Atmospheric Environment
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• 제10권1호
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• pp.42-50
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• 2016

This study presents a performance evaluation of four different land surface models (LSM) available in Weather Forecast Research (WRF). The research site was located in Haean Basin in South Korea. The basin is very unique by its geomorphology and topography. For a better representation of the complex terrain in the mesoscale model were used a high resolution topography data with a spatial resolution of 30 meters. Additionally, land-use layer was corrected by ground mapping data-sets. The observation equipments used in the study were an ultrasonic anemometer with a gas analyzer, an automatic weather station and a tethered balloon sonde. The model simulation covers a four-day period during autumn. The result shows significant impact of LSM on meteorological simulation. The best agreement between observation and simulation was found in the case of WRF with Noah LSM (WRF-Noah). The WRF with Rapid Update Cycle LSM (WRF-RUC) has a very good agreement with temperature profiles due to successfully predicted fog which appeared during measurements and affected the radiation budget at the basin floor. The WRF with Pleim and Xiu LSM (WRF-PX) and WRF with Thermal Diffusion LSM (WRF-TD) performed insufficiently for simulation of heat fluxes. Both overestimated the sensible and underestimated the latent heat fluxes during the daytime.

• 수산해양기술연구
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• 제50권4호
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• pp.427-434
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• 2014

Although ex situ target strength (TS) measurements using dual- and split-beam systems have become the primary approach of estimating fish abundance, theoretical model estimation is a powerful tool for verifying the measurements, as well as for providing values when making direct measurements is difficult. TS values for 20 samples of live bambooleaf wrasse (Pseudolabrus japonicus) whose target length (TL) ranged between 13.7 and 21.3 cm were estimated theoretically using the Kirchhoff-ray mode model, and the TS values for 18 live fish samples were additionally measured at ${\sim}0^{\circ}$ tilt angle to the swimming aspect using a tethered method at a frequency of 120 kHz to verify the theoretical values. The digitizing intervals used to extract the fish body and swim bladder morphology in the X-ray photographs significantly affected the calculated TS patterns, but variations based on the speed of sound and density ratio values for the general range of fish flesh were relatively small (within 1 dB). Close agreement was observed between the measured and theoretical TS values, and the correlation between the average TS and body length of the fish could be calculated accurately as <$TS_{120kHz}$>= 20logTL (cm) -71.6 using the theoretical method.

• 수산해양기술연구
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• 제46권2호
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• pp.157-163
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• 2010

The indirect target strength (TS) estimation method which uses the Kirchhoff ray mode model (KRM model) was discussed to apply for a biomass estimation in the water of mixed species. TS of 25 live scorpion fishes for 120kHz were measured by a tethered method and of others dominant 5 species in the marine ranching ground of Jeju coastal water including a scorpion fish were also estimated by KRM model. The measurement TS of scorpion fish well agreed with the theoretical values and the standard formula of scorpion fish was estimated as $TS_{120kHz}=20Log\;(L)-72.9$ ($r^2=0.67$). TScm values estimated on trial to each sample of dominant 5 species were from -69.3dB to -75.1dB at 120kHz and they were in the general range of swimbladdered fish. It was clarified that TS by KRM model can be used to estimate fish biomass estimation by increasing a sample number and is more effective under the condition that there is rare TS information for inhabiting species in mixed-species area.