• Title/Summary/Keyword: Test Validation

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Development of kNN QSAR Models for 3-Arylisoquinoline Antitumor Agents

  • Tropsha, Alexander;Golbraikh, Alexander;Cho, Won-Jea
    • Bulletin of the Korean Chemical Society
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    • 제32권7호
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    • pp.2397-2404
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    • 2011
  • Variable selection k nearest neighbor QSAR modeling approach was applied to a data set of 80 3-arylisoquinolines exhibiting cytotoxicity against human lung tumor cell line (A-549). All compounds were characterized with molecular topology descriptors calculated with the MolconnZ program. Seven compounds were randomly selected from the original dataset and used as an external validation set. The remaining subset of 73 compounds was divided into multiple training (56 to 61 compounds) and test (17 to 12 compounds) sets using a chemical diversity sampling method developed in this group. Highly predictive models characterized by the leave-one out cross-validated $R^2$ ($q^2$) values greater than 0.8 for the training sets and $R^2$ values greater than 0.7 for the test sets have been obtained. The robustness of models was confirmed by the Y-randomization test: all models built using training sets with randomly shuffled activities were characterized by low $q^2{\leq}0.26$ and $R^2{\leq}0.22$ for training and test sets, respectively. Twelve best models (with the highest values of both $q^2$ and $R^2$) predicted the activities of the external validation set of seven compounds with $R^2$ ranging from 0.71 to 0.93.

Validation of a 750 kW semi-submersible floating offshore wind turbine numerical model with model test data, part I: Model-I

  • Pham, Thanh Dam;Shin, Hyunkyoung
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제11권2호
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    • pp.980-992
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    • 2019
  • This paper describes a model test and numerical simulation of a 750-kW-semi-submersible platform wind turbine under several wind and wave conditions for validation of the numerical simulation model. The semi-submersible platform was designed to support the 750-kW-wind turbine class and operate at a water depth of 50 m. The model tests were performed to estimate the performance characteristics of the wind turbine system in the wide tank of the University of Ulsan. Motions and loads of the wind turbine system under the wind and wave conditions were measured and analyzed. The NREL-FAST code was used to simulate the wind turbine system, and the results were compared with those of the test model. The results demonstrate that the numerical simulation captures noticeably the fully coupled floating wind turbine dynamic responses. Also, the model shows a good stability and small responses during waves, wind, and operation of the 750-kW-floating offshore wind turbine.

CFD 검증용 데이터베이스 구축을 위한 손상 선박의 횡동요 감쇠 운동에 대한 실험적 연구 (Experimental Study on Free Roll Decay Motions of a Damaged Ship for CFD Validation Database)

  • 이성균;유지명;이현호;이신형;이기표
    • 대한조선학회논문집
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    • 제49권1호
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    • pp.52-59
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    • 2012
  • Among many factors to be considered for higher safety level requirements, the hull stability in intact and damaged conditions in seaways is of utmost importance. Since the assessment of a damaged ship is complicated due to the highly non-linear behavior, it is widely acknowledged that computational fluid dynamics (CFD) methods are one of the most feasible approaches. Although many research activities are being reported on the damaged ship stability recently, most of them are not designed for validation of CFD studies. In this study, well-designed model tests were performed to build a CFD validation database, which is essential in developing better CFD methods for the damage stability assessment. The geometry of the damaged compartment and test conditions were determined based on preliminary CFD simulations. Free roll decay tests in calm water with both intact and damaged ships were performed and the roll motion characteristics were compared. The damaged ship showed a larger roll damping coefficient and more rapid decrease of roll amplitude than the intact ship. The primary reason of these efforts can be explained by the movement of the flooded water.

영아/걸음마기 아동 환경 평정 척도 타당화 연구 (ll) (A Validation Study for the Infant/Toddler Environment Rating Scale(ll))

  • 이완정
    • 대한가정학회지
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    • 제36권6호
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    • pp.95-108
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    • 1998
  • This study is the second study which was aimed to validate the Infant/ Toddler Environment Rating Scale(ITERS). The test-retest reliability included 10 infant/toddler classes among 30 national/public and private child care centers in Inchon city which had been observed in the first validation study. The Spearman's correlation coefficient for test-retest reliability was ranged from .52 to .84. In addition, two raters observed 10 family day care centers in Inchon city, where two observers independently rated each centers on the ITERS during a single visit. The Spearman's correlation coefficient for interrater reliability was ranged from.72 to .99 For the second measure of content validity, experts who were working in day care centers and who were graduate students, lecturers, or professors majoring child studies rated the appropriateness of each ITERS items for the provision of high-quality programs for infants and toddlers, using a 1(low) to 5(high) scale. The mean rating was ranged from 2.52 to 4.52. In sum, when the rating scores were analyzed by the type of child care centers, national/public child care centers have better quality than private or family child care centers.

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공기압 실린더 가속모형의 유효성 평가에 관한 연구 (A Study on Validation of Accelerated Model for Pneumatic Cylinder)

  • 강보식;김형의;장무성;송창섭
    • 대한기계학회논문집A
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    • 제33권10호
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    • pp.1139-1143
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    • 2009
  • Pneumatic cylinder is widely used as key component of various industry fields just like automation production line. Recently, people begin to pay attention to reduce development period and cost of pneumatic cylinder so research requirements of accelerated life test of pneumatic cylinder have been increased more than ever. In this research, we shall evaluate availability of acceleration model by statistical analysis of acceleration model's predicted value and life data which acquired in a real operation condition after finish accelerated life test of pneumatic cylinder. Also to predict the life of pneumatic cylinder in the operation condition we shall develop new acceleration model equations.

VDL Mode 2 시스템 검증을 위한 운용시험장비 설계 (Design of Operational Test Equipments for VDL Mode 2 System Validation)

  • 배중원;김태식;이해창
    • 항공우주시스템공학회지
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    • 제2권3호
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    • pp.33-39
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    • 2008
  • VDL Mode 2 is one of air-to-ground VHF digital data link technologies. The VDL Mode 2 system is designed to be an air-to-ground subnetwork of the Aeronautical Telecommunication Network (ATN) using the AM(R)S band and it is organized according to the Open System Interconnection (OSI) model (defined by ISO). It can be used in ATS Applications especially for ATC communication such as CPDLC and ADS as well. And It is expected VDL Mode 2 replaces ACARS(Aircraft Communications Addressing and Reporting System) which has broadly been used for over 20 years. This paper presents the result of design of operational test equipments for the validation of VDL Mode 2 system under development in KARI.

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유아용 반사회적 행동 평가 척도의 타당화 연구 (Validation of the Antisocial Behavior Scale)

  • 이양희;김윤영
    • 아동학회지
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    • 제23권3호
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    • pp.109-121
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    • 2002
  • The subjects of this validation of the Antisocial Behavior Scale(ABS) consisted of 323 normal and 29 clinically referred preschoolers between the ages of four and six years. The ABS has 3 factors: oppositional/aggression, nonsocial/egoism, and inattention. Results showed high test-retest reliability(r=.83-.90). The scale discriminated between the normal and clinical groups. The first(oppositional/aggression) and the third(inattention) factors of the ABS, measuring externalizing behaviors, correlated highly with the Externalizing Problems and Attention Problems Scales of the Korean Version of Child Behavior Checklist(K-CBCL). The second(nonsocial/egoism) factor of the ABS, measuring emotional areas correlated highly with the Emotional Liability Scale of the K-CBCL.

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풍력발전시스템 성능 해석 S/W의 초기 검증에 관한 연구 (Preliminary Validation of Wind Turbine Generator System Performance Analysis S/W, WINSIM)

  • 문정희;노태수;박종혁;김성주
    • 한국항공우주학회지
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    • 제37권2호
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    • pp.209-214
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    • 2009
  • 본 논문에서는 풍력발전시스템의 정상 및 과도 응답과 같은 동적 거동 분석은 물론 피치제어 시스템의 성능 예측을 위하여 개발된 시뮬레이션 소프트웨어의 검증을 위하여 실제 현장에서 측정한 자료와 비교 검증을 수행하였고 실제와 유사하도록 시스템 모델링 및 소프트웨어의 개선 방향을 제시함으로써 향후 본 연구를 통하여 개발한 소프트웨어의 유용성을 제시하고자 한다.

암호화 모듈 평가 프로그램(CMVP) 표준인 Derived Test Requirement(DTR) of FIPS 140-2 분석 (Analysis FIPS 140-2 DTR(Derived Test Requirement of FIPS 140-2 of CMVP(Cryptographic Module Validation Program))

  • 이병석;정성민;박성근;김석우;박일환
    • 한국정보보호학회:학술대회논문집
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    • 한국정보보호학회 2003년도 동계학술대회
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    • pp.311-316
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    • 2003
  • 정보통신기술의 발달로 대부분 사회의 기반구조가 사이버 사회로 전환되었고 다양한 형태의 경제사회 활동을 수행키 위해 정보보호제품의 활용이 극대화되었으며 더욱 중요시되었다. 이러한 사회흐름에 기반하여 정보보호제품의 안전한 선택 및 사용을 위한 기본적 선택기준은 검증받은 암호화 모듈을 바탕으로 하는 정보보호제품에 대한 신뢰 기관의 안전성 평가 결과일 것이다. 암호화 모듈에 대한 안전성 평가로 가장 널리 참조되는 것은 미국의 NIST(National Institute of Standards and Technology)가 수행하는 CMVP(Cryptographic Module Validation Program)이며, 세계적으로 인정받고 있다. 본 논문에서는 암호 모듈의 평가체계에 대해 설명하였으며 그 기준인 FIPS 140-2 DTR을 분석하여 향후 개발 가능한 CMVP의 안전성 평가 툴 기준에 대해 제시하였다.

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5G MEC 기반 로봇 엔진 원격 구동을 위한 클라우드 로보틱스 시스템 구성 및 실증 (Validation of Cloud Robotics System in 5G MEC for Remote Execution of Robot Engines)

  • 구세완;강성규;정원홍;문형일;양현석;김영재
    • 로봇학회논문지
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    • 제17권2호
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    • pp.118-123
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    • 2022
  • We implemented a real-time cloud robotics application by offloading robot navigation engine over to 5G Mobile Edge Computing (MEC) sever. We also ran a fleet management system (FMS) in the server and controlled the movements of multiple robots at the same time. The mobile robots under the test were connected to the server through 5G SA network. Public 5G network, which is already commercialized, has been temporarily modified to support this validation by the network operator. Robot engines are containerized based on micro-service architecture and have been deployed using Kubernetes - a container orchestration tool. We successfully demonstrated that mobile robots are able to avoid obstacles in real-time when the engines are remotely running in 5G MEC server. Test results are compared with 5G Public Cloud and 4G (LTE) Public Cloud as well.