• Korean Journal of Clinical Laboratory Science
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• v.55 no.3
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• pp.132-142
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• 2023

Human leukocyte antigen (HLA) typing was performed in the diagnostic immunology laboratory of the Seoul National University Hospital. Among 611 HLA-DR tests, specific bead reactions suspected of being false positive and false negative in Lot 20 reagents were found. Therefore, we aimed to identify the factors causing cut-off corrections by examining cases where cut-off corrections were not made for 533 test results and cases where cut-off corrections were made for 78 cases after the cut-off corrections of specific beads. Frequency analysis was conducted to verify the demographic characteristics, and descriptive statistics were used to assess the humidity in the laboratory as a variable. Cross-tabulation was done to examine the association between cut-off corrections and demographic characteristics. Independent samples t-tests were conducted to verify the difference in humidity based on cut-off corrections. Finally, logistic regression analysis was conducted to examine the relationship between humidity levels and the rate of cut-off corrections, and results showed as the humidity level in the laboratory highs, the number of cut-off corrections decreased by a factor of 0.986. This suggests cut-off corrections rate increases when the humidity lowers. Therefore, it indicates that humidity in the laboratory is also a factor that affects HLA typing results.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.4
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• pp.122-134
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• 2009

Purpose: The purpose of this study is to know the blood stasis pattern for the patients who had hysterectomy. Methods: Among the patients who had hysterectomy in the department of obstetrics and gynecology, OO medical center from March 3rd 2009 to October 21st 2009, subjects who met inclusion criteria and submitted appropriate questionnaire. We compared blood stasis score and operational method, age, BMI, past operation history of abdominal and pelvic site, parity, whether adhesiolysis, oriental medicine intervention was done. For statistics, we used independent samples t-test, oneway analysis of variances(ANOVA) and SPSS version 13.0 for windows. Results: Blood stasis score of the subtotal hysterectomy group ($44.43{\pm}15.01$) is higher than that of the total hysterectomy group($39.04{\pm}12.46$). Blood stasis score under the age 40($51.88{\pm}12.68$) is higher than 40-49 age patients($40.34{\pm}14.24$) and over the age 50 patients($41.62{\pm}13.46$). There is no statistically significant difference between laparoscopic and abdominal trial, whether adhesiolysis, oriental medicine intervention was done, BMI, past operation history abdominal and pelvic site, parity, chief complaint before hysterectomy, oriental medicine intervention. Conclusion: Through the results showed, when traditional Korean medical doctors use static blood medication, history of hysterectomy and age should be considered as the history of subtotal hysterectomy and younger age tend to have a higher rate of a blood stasis pattern. We need a further study to develop blood stasis indicators with a validated questionnaire, and more subjects involved at multiple institutions.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.6C
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• pp.367-377
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• 2008

As part of study to develop LRFD (Load and Resistance Factor Design) codes for foundation structures in Korea, resistance factors for static bearing capacity of driven steel pipe piles were calibrated in the framework of reliability theory. The 57 data sets of static load tests and soil property tests conducted in the whole domestic area were collected and these load test piles were sorted into two cases: SPT N at pile tip less than 50, SPT N at pile tip equal to or more than 50. The static bearing capacity formula and the Meyerhof method using N values were applied to calculate the expected design bearing capacities of the piles. The resistance bias factors were evaluated for the two static design methods by comparing the representative measured bearing capacities with the expected design values. Reliability analysis was performed by two types of advanced methods: the First Order Reliability Method (FORM), and the Monte Carlo Simulation (MCS) method using resistance bias factor statistics. The target reliability indices are selected as 2.0 and 2.33 for group pile case and 2.5 for single pile case, in consideration of the reliability level of the current design practice, redundancy of pile group, acceptable risk level, construction quality control, and significance of individual structure. Resistance factors of driven steel pipe piles were recommended based on the results derived from the First Order Reliability Method and the Monte Carlo Simulation method.

• Tuberculosis and Respiratory Diseases
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• v.86 no.3
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• pp.203-215
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• 2023

Background: Surgical resection is the standard treatment for early-stage lung cancer. Since postoperative lung function is related to mortality, predicted postoperative lung function is used to determine the treatment modality. The aim of this study was to evaluate the predictive performance of linear regression and machine learning models. Methods: We extracted data from the Clinical Data Warehouse and developed three sets: set I, the linear regression model; set II, machine learning models omitting the missing data: and set III, machine learning models imputing the missing data. Six machine learning models, the least absolute shrinkage and selection operator (LASSO), Ridge regression, ElasticNet, Random Forest, eXtreme gradient boosting (XGBoost), and the light gradient boosting machine (LightGBM) were implemented. The forced expiratory volume in 1 second measured 6 months after surgery was defined as the outcome. Five-fold cross-validation was performed for hyperparameter tuning of the machine learning models. The dataset was split into training and test datasets at a 70:30 ratio. Implementation was done after dataset splitting in set III. Predictive performance was evaluated by R² and mean squared error (MSE) in the three sets. Results: A total of 1,487 patients were included in sets I and III and 896 patients were included in set II. In set I, the R² value was 0.27 and in set II, LightGBM was the best model with the highest R² value of 0.5 and the lowest MSE of 154.95. In set III, LightGBM was the best model with the highest R² value of 0.56 and the lowest MSE of 174.07. Conclusion: The LightGBM model showed the best performance in predicting postoperative lung function.

• The Journal of Korean Society for School & Community Health Education
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• v.24 no.1
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• pp.1-15
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• 2023

Objectives: The purpose of this study was to identify the major influencing factors of breast cancer death and to suggest policy measures to promote the health of breast cancer patients. Methods: The method of this study performed statistical analysis by applying weights to 2,300 cases of breast cancer registration statistics in Korea collected in 2018 due to the relatively small number of mortality data compared to survival. Statistical processing of the collected data was analyzed using SPSS 26.0. Results: The epidemiologic characteristics of death in breast cancer patients were 31.8% in those aged 70 years or older, and the mortality rate was 5.25 times higher in patients aged 70 years or older than those aged 39 years or younger. The anatomical site code was 36.4% in C50.4~C50.6, and the mortality rate was 1.82 times higher in C50.4~C50.6 than in C50.0~C50.1. The tumor size was 40.4% and larger than 4cm, and the mortality rate was 4.53 times higher in tumors larger than 4cm than those smaller than 1cm. The degree of differentiation was 13.9% in the poorly differentiated group, and the mortality rate was 4.38 times higher in the poorly differentiated group than in the highly differentiated group. In the hormone receptor test, non-triple negative cases were 59.6%, and the mortality rate was 0.57 times lower in non-triple negative cases than in triple negative cases. As for lymph node involvement, the presence or absence of lymph node involvement was 78.8%, and the mortality rate with lymph node involvement was 1.36 times higher than that without lymph node involvement. The survival period of 13 to 24 months was the highest at 26.5%, and the average survival period was 25.68 months (±14.830). Conclusion: A policy to advance the timing of national health examinations for early detection of breast cancer is necessary. In addition, a bill for the mandatory placement of health educators in medical institutions for patients with special diseases such as breast cancer should be prepared.

• Journal of Korea Entertainment Industry Association
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• v.13 no.5
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• pp.185-193
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• 2019

Young children facilitate their social and emotional development by doing a lot of play activities with their peers. As an empirical survey study, this study is aimed at analyzing how the peer play interaction influences peer competency and self-regulation. To achieve that, a questionnaire survey was conducted with 271 young children aged 5 years who were going to the kindergarten in the G district of Seoul. With the data collected in the survey, frequency analysis, descriptive statistics, reliability test, correlation analysis and regression analysis were conducted by SPSS program. The analysis results are presented as follows: firstly, peer play interaction positively influenced young children's sociability, pro-sociality, and leadership as their peer competency factors; secondly, peer play interaction positively influenced their patience, endurance of waiting, and adaptation as their self-regulation factors. This study drew the conclusion that peer play interaction is a critical variable to predict young children's peer competency and self-regulation. Therefore, it will be necessary to continuously develop a variety of play activity programs which young children can join in the inside and outside of kindergarten in order to helps young children improve their peer competency and self-regulation, and to actively connect the programs with Nuri curriculum.

• 한국노년학
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• v.31 no.2
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• pp.211-222
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• 2011

The purpose of this study was to assess pain, life satisfaction, sleep pattern, and depression and the relations between these in elderly women with ostearthritis. Methods: The subjects were 124 elderly women with osteoarthritis at senior center in C city. Data were analyzed by descriptive statistics, Pearson's correlation coefficients, and multiple regression with SPSS/WIN 14.0. Results: The major findings of this study were as follows. 1) The mean score of variables were pain 2.58, life satisfaction 65.4, sleep pattern 37.6 and depression 13.58. 2) 43.5% of the subjects belonged to depression group. 3) There were significant relationships between depression and pain, life satisfaction, sleep pattern. 4) Significant factors influencing depression were life satisfaction, pain and sleep pattern. These factors explained 48% of depression in elderly women with ostearthritis. Among them, life satisfaction was the most significant factor. Conclusion: These finding give useful information for constructing an intervention and preventive program depression in the elderly women with osteoarthrtitis.

• 한국노년학
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• v.29 no.3
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• pp.1159-1182
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• 2009

The purpose of this study is to examine everyday emotional experience of urban elderly in Korea. Specifically, this study explores gender differences in the effect of place/location of activity and companionship on the daily emotional experience. Data were collected from 148 urban elderly (men=76, women=72) in Seoul, using Experience Sampling Method(ESM). The unit of analysis was the self-report and in total 5,530 self-reports were provided. The statistical methods used for the data analyses were descriptive statistics, t-test, χ² verification, and ANOVA. The major findings are as follows. First, the elderly in Korea spend a quite substantial portion of their time at home, and they spend the largest share of their time in company with their spouse. Second, women report higher intensity of stress and irritation than men in terms of overall emotional experience. Third, the effect of activity location and companionship on emotional experience turned out to be different depending on gender. Emotional experience of daily lives and overall quality of life are shown to be inter-related. Based on these findings, this study provides a significant implication that situational contexts of experience should be considered in order to understand the daily emotional experience of the contemporary Korean elderly.

• 한국노년학
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• v.30 no.3
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• pp.695-708
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• 2010

Purpose: This study was to explore the factors affecting on Dietary Behavior Change of the vulnerable elderly based on the Stage of Change. Methods: This study was a secondary analysis of the data collected from 1,262 elderly who were participated in the case management program. Total 984 participants who responded all questionnaire were included in the analysis. The variables included general characteristics, health behavior, health status, and dietary behavior stage. The data collected were analyzed by descriptive statistics, trend test and multi-variate logistic regressions. Results: about twenty four percent of the vulnerable elderly subject was pre-contemplation stage and 46.1% of them was contemplation stage of dietary behavior. Having a depressive mood, dependance of Instrumental Activity of Daily living, and being medicaid affected on starting or on maintaining healthy dietary behavior in vulnerable elderly negatively. Conclusion: The tailored nutritional intervention depending on dietary behavior stage are needed for the vulnerable elderly to improve the health. The program which can maintain the function remained of elderly and give psychological support together will be more effective.

• 한국노년학
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• v.31 no.4
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• pp.905-923
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• 2011

The purpose of this study is to examine factors affecting the conflict between grandparents raising grandchildren and adult children. The data were based on the panel survey to explore korean retirement and income study conducted by National Pension Service in 2009. For this study, 287 parenting grandparents rearing grandchild are selected from the survey. Included variables are a demographic factor, a economic factor, a caregiving-related factor, a health factor, and a family relationship factor. The data were analyzed using descriptive statistics, t-test, co-relation and logistic regression, with SPSS WIN 18.0 program. The results are as follows: First, when grandparents are male, older, highly educated, having no religion, and unemployed, a conflict with their adult children grows. Second, when grandparents do not have earned income or financial income, but have private income transfers, a conflict with their adult children is high. Third, when grandchildren are younger, there are no caregiving rewards, economic activities suspension or reduction because of caregiving, a conflict with their adult children is strong. Also, when grandparents' physical health is good, but their mental health is poor, a conflict with their adult children increases. Fourth, when grandparents' satisfactions with family relationship and spouse relationship are low, but their satisfaction with adult children relationship is high, a conflict with their adult children rises. This study suggests that unlike in the past, grandparents raising grandchildren can no longer make sacrifice themselves for their adult children, but they expect proper exchange between parents and children. Therefore, there needs to be understanding of grandparents raising grandchildren and further studies of a conflict between grandparents raising grandchildren their adult children.