• Journal of Biosystems Engineering
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• v.23 no.3
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• pp.229-244
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• 1998

This study was performed to determine proper fan and heater management schemes for natural air drying of rough rice in round steel bin with stirring device under Korean weather conditions. A computer simulation model was developed to predict moisture content changes, energy requirements, and drymatter losses during drying of rough rice by natural air. Drying test was conducted to validate the simulation model using round steel bin of holding capacity of 300ton at Rice Processing Complex in Jincheon. The bin was filled with rough rice every day and mixing by stirring device. Moisture contents, ambient air temperatures, relative humidities, static pressures in plenum chamber in the bin, airflow rates, and electrical and fuel energy were measured. Relative errors of moisture content changes predicted by the simulation model were below 5ft, and relative errors of final moisture content, final grain weight, required energy ranged from 0.9% to 6%. These not levels indicated that the simulation model can satisfactorily predict the performance factors of natural air drying system such as drying rates and energr consumptions comparing error level of 10% to 15% in other drying simulation models generally used in dryer desists. Twelve different fan and heater management schemes were evaluated using the computer simulation model based on three hourly weather data from Suweon for the period of 1952-1994. The best management schemes were selected comparing the drymatter losses, required drying times, required energy consumptions. Operating fan without heating only when ambient relative humidity was below 85% or 90% appeared to be the most effective method of In operation in favorable drying weather. Under adverse drying climates or to reduce required drying time, operating fan continuously, and heating air with $1.5^{\circ}C$ temperature rise only when ambient relative humidity was over 85% appeared to be the most suitable method.

• Journal of the Korean Data and Information Science Society
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• v.27 no.3
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• pp.741-747
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• 2016

The aim of study was to estimate genetic parameter of carcass traits in commercial Hanwoo steer using national animal model for selection of superior bull. Analyzed data (n=5,843) on carcass traits was collected from 107,020 Hanwoo steer. The animal model was used to estimate heritability and genetic correlations. The estimated heritability of carcass traits were 0.19, 0.17, 0.20 and 0.23 for carcass weight, eye muscle area, backfat thickness and marbling score, respectively. The estimated heritability for carcass traits in commercial Hanwoo are low than estimated heritability of national progeny test population for selection of superior bull because breeding environment, genetic performance of cow and feeding day was different. Therefore, we suggests that animal model can include practical genetic variable based on national animal model to improve genetic performance in commercial Hanwoo.

• The Journal of Korean Academic Society of Nursing Education
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• v.30 no.1
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• pp.5-18
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• 2024

Purpose: This study aimed to identify whether there is a difference between an online-based community psychiatric nursing practice program with the ARCS model and a conventional community psychiatric nursing practice program in promoting nursing students' learning motivation, knowledge of community psychiatric nursing, communication skills, and learning self-efficacy. Methods: This study used a quasi-experimental design with a non-equivalent control group. The participants were 44 nursing students at three nursing colleges in Gyeongsangbuk-do. The experimental group was provided the online-based community psychiatric nursing practice program with ARCS model, while the control group was provided the conventional community psychiatric nursing practice program from July 9, to September 3, 2022. Both groups received practice training 8 hours a day, 5 days two weeks. The collected data were analyzed using the exact χ², Mann-Whitney U-test, and Quade's two-way ANCOVA with the IBM SPSS Statistics 28.0 program. Results: The results of the comparison of an experimental group training with the online-based community psychiatric nursing practice program with ARCS model and a control group training with the conventional community psychiatric nursing practice program showed that, there was no statistically significant difference between the two groups in learning motivation knowledge of community psychiatric nursing, and learning self-efficacy. However, communication skills were statistically significantly higher in the experimental group (F=6.23, p=.017). Conclusion: The online-based community psychiatric nursing practice program with ARCS model can be used as a substitute learning to improve community psychiatric nursing capabilities in situations when clinical practice is suspended due to infectious diseases such as coronavirus disease 2019 or when is a shortage of community psychiatric nursing practice institutions.

• Journal of Oriental Neuropsychiatry
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• v.23 no.2
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• pp.99-120
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• 2012

Objectives : The oriental medicine Jangwonhwan, a boiled extract of 12 medicinal herbs/mushrooms, has been prescribed to patients with cognitive dysfunction, as originally described in the Korean medical text, DonguiBogam(amnesia chapter). Recently, a modified formula of Jangwonhwan (LMK02-Jangwonhwan) consisting of seven medicinal plants/mushrooms, was shown to reduce the ${\beta}$-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model for Alzheimer's disease. The toxicity of LMK02-Jangwonhwan was investigated in SD rats, by a daily oral administration for 13 weeks and NOAEL(No observed adverse effect dose), a definite toxic dose and target organ, as well. Methods : Quality control of the tablet form of LMK02-Jangwonhwan was established by estimating the indicative components, Ginsenoside Rg3 of Red Ginseng and Decursin of Angelicagigas Nakai. The toxicity of LMK02-Jangwonhwan was investigated in 6 week old, specific pathogen free (SPF), Sprageu-Dawley rats by oral administration. Each test group consisted of 10 male and 10 female rats. The groups received doses of 500, 1,000 or 2,000 mg/kg/day of test substance for 13 weeks. The clinical signs, death rate, body weight, food consumption, ophthalmic examination, urinalysis, hematological and serum biochemistry, organ weight and pathological changes were examined and compared with those of the control group. Results : The 13-week repeated oral treatment doses didn't result in any specific symptoms or death. There were no significant changes in the rat's weight and food consumption. Further, ophthalmic examination, urinalysis, hematological, serum biochemistry test and organ weight revealed no significant differences. Conclusions : The no-observed-adverse-effect level(NOAEL) of LMK02 for male and female Sprague-Dawley rats was determined as 2,000mg/kg/day and the target organ wasn't confirmed. Because no significant adverse effects were observed, the target organ could not be determined.

• Journal of Oriental Neuropsychiatry
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• v.26 no.3
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• pp.319-336
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• 2015

Objectives: The object of this study was to evaluate the cognition and motor function recovery effects of Sungshim-san (SSS), a traditional Korean cardio-protective polyherbal formula in the severe rat stroke, permanent middle cerebral artery occlusion (pMCAO) model. Methods: The experimental animals were divided into 6 groups. SSS aqueous extracts (yield=16.82%; 400, 200 and 100 mg/kg) were administered orally by using Sonde, once daily, for 28 continuous days from 24 hrs post-pMCAO. Donepezil 10 mg/kg, a representative drug for dementia, was used as a reference drug. The body weight changes, infarct/defect sizes, sensorimotor function and cognitive motor behavior were serially monitored. Limb placing and body-swing test for sensorimotor functions were conducted at 1 day before operation (base line), and 1, 3, 7, 14, 21 and 28 days post-pMCAO; and water maze test for the cognitive motor behavior was conducted at 14 and 28 days post-pMCAO, respectively. Results: Focal cerebral cortex infarct and defects due to pMCAO resulted in marked decreases of body weight, disorders of sensorimotor functions and cognitive motor behaviors. However, the pMCAO-related ischemic damages were markedly and dose-dependently inhibited by treatment with SSS 400 and 200 mg/kg, respectively. Donepezil markedly decreased the body weight and gains, as compared with pMCAO control rats; however, SSS 400 and 200 mg/kg favorably ameliorated the pMCAO-induced decreases in body weight and gains. SSS 100 mg/kg treated rats did not show any favorable effects on the pMCAO-related ischemic damages, as compared with pMCAO control rats. Conclusions: The results of the study indicated that oral administration of SSS 400 and 200 mg/kg accelerated cognition and motor function recovery in the rat pMCAO model. The treatment effect was potentially mediated by neuroprotection via the known augmentation of cerebral antioxidant defense system of SSS itself or its individual herbal components. Especially, the overall effects of SSS 200 mg/kg were similar to those of donepezil 10 mg/kg, but less toxic.

• The Journal of Korean Medicine
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• v.30 no.2
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• pp.1-16
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• 2009

Objectives: This study investigated the effect of Yukmijihwangtang on cerebral ischemia-induced learning and memory impairment by middle cerebral artery (MCA) occlusion in rats. Methods: The ability of learning and memory of rats was measured using the eight-arm radial maze and the passive avoidance test, and profile of cholinergic neuron was assessed in the medial septum and hippocampus region by immuno-histochemistry. Results: 1. No differences were found between groups in the number of correct choices in acquisition performance during the eight-arm radial maze task. 2. No differences were found between groups on day 1 in the error rate in acquisition performance, which is defined as the number of enters into the same arm more than once within five minutes. After 5 to 6 days of test, the number of errors was significantly reduced in the Yukmijihwangtang group (forebrain ischemia group with Yukmijihwangtang treatment), compared with the ischemia group. 3. The memory processes significantly improved in the Yukmijihwangtang group according to results of the passive avoidance test. 4. The appearance of AchE (acetylcholinesterase) in the CA1 region of hippocampus significantly decreased in the ischemia group, compared with the sham group (untreated group). The appearance of AchE in the same region significantly increased in the Yukmijihwangtang group, compared with the ischemia group. 5. The appearance of ChAT (choline acetyltransferase) in the CA1 region of the hippocampus and medial septum decreased in the ischemia group, compared with the sham group. The appearance of ChAT in the same region significantly increased in the Yukmijihwangtang group, compared with the ischemia group Conclusions: This study provides evidence that Yukmijihwangtang is effective for reviving the ability of learning and memory and damaged neurons in rats with experimental cerebral ischemia.

• Journal of Pharmacopuncture
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• v.18 no.3
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• pp.42-48
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• 2015

Objectives: The aim of the study is to investigate both the single-dose intramuscular injection toxicity and the approximate lethal dose of water-soluble Carthami-flos and Cervi cornu parvum pharmacopuncture (WCFC) in male and female Sprague-Dawley (SD) rats. Methods: The study was conducted at Biotoxtech Co. according to the Good Laboratory Practice (GLP) regulation and the toxicity test guidelines of the Ministry of Food and Drug Safety (MFDS) after approval of the Institutional Animal Care and Use Committee. Dosages for the control, high dose, middle dose and low dose groups were 0.5 mL/animal of saline and 0.5, 0.25 and 0.125 mL/animal of WCFC, respectively. WCFC was injected into the muscle of the left femoral region by using a disposable syringe (1 mL, 26 gauge). The general symptoms and mortality were observed 30 minutes, 1, 2, 4, and 6 hours after the first injection and then daily for 14 days after the injection. The body weights of the SD rats were measured on the day of the injection (before injection) and on the third, seventh, and fourteenth days after the injection. Serum biochemical and hematologic tests, necropsy examinations, and histopathologic examinations at the injection site were performed after the observation period. Results: No deaths, abnormal clinical symptoms, or significant weight changes were observed in either male or female SD rats in the control or the test (0.125, 0.25, and 0.5 mL/animal) groups during the observation period. No significant differences in hematology and serum biochemistry and no macroscopic abnormalities at necropsy were found. No abnormal reactions at injection sites were noted on the topical tolerance tests. Conclusion: The results of this single-dose toxicity study show that WCFC is safe, its lethal doses in male and female SD rats being estimated to be higher than 0.5 mL/animal.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.1197-1199
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• 2003

ROCSAT-2 mission is to daily image over Taiwan and the surrounding area for disaster monitoring, land use, and ocean surveillance during the 5-year mission lifetime. The satellite will be launched in December 2003 into its mission orbit, which is selected as a 14 rev/day repetitive Sun-synchronous orbit descending over (120 deg E, 24 deg N) and 9:45 a.m. over the equator with the minimum eccentricity. National Space Program Office (NSPO) is developing a ROCSAT-2 Image Processing System (IPS), which aims to provide real-time high quality image data for ROCSAT-2 mission. A simulated ROCSAT-2 image, based on Level 1B QuickBird Data, is generated for IPS verification. The test image is comprised of one panchromatic data and four multispectral data. The qualification process consists of four procedures: (a) QuickBird image processing, (b) generation of simulated ROCSAT-2 image in Generic Raw Level Data (GERALD) format, (c) ROCSAT-2 image processing, and (d) geometric error analysis. QuickBird standard photogrammetric parameters of a camera that models the imaging and optical system is used to calculate the latitude and longitude of each line and sample. The backward (inverse model) approach is applied to find the relationship between geodetic coordinate system (latitude, longitude) and image coordinate system (line, sample). The bilinear resampling method is used to generate the test image. Ground control points are used to evaluate the error for data processing. The data processing contains various coordinate system transformations using attitude quaternion and orbit elements. Through the qualification test process, it is verified that the IPS is capable of handling high-resolution image data with the accuracy of Level 2 processing within 500 m.

• Journal of Biosystems Engineering
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• v.43 no.3
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• pp.219-228
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• 2018

Purpose: This study evaluated the feasibility of a near-infrared spectroscopy technique for the rancidity prediction of soybean oil. Methods: A near-infrared spectroscopy technique was used to evaluate the rancidity of soybean oils which were artificially deteriorated. A soybean oil sample was collected, and the acid values were measured using titrimetric analysis. In addition, the transmission spectra of the samples were obtained for whole test periods. The prediction model for the acid value was constructed by using a partial least-squares regression (PLSR) technique and the appropriate spectrum preprocessing methods. Furthermore, optimal wavelength selection methods such as variable importance in projection (VIP) and bootstrap of beta coefficients were applied to select the most appropriate variables from the preprocessed spectra. Results: There were significantly different increases in the acid values from the sixth days onwards during the 14-day test period. In addition, it was observed that the NIR spectra that exhibited intense absorption at 1,195 nm and 1,410 nm could indicate the degradation of soybean oil. The PLSR model developed using the Savitzky-Golay $2^{nd}$ order derivative method for preprocessing exhibited the highest performance in predicting the acid value of soybean oil samples. onclusions: The study helped establish the feasibility of predicting the rancidity of the soybean oil (using its acid value) by means of a NIR spectroscopy together with optimal variable selection methods successfully. The experimental results suggested that the wavelengths of 1,150 nm and 1,450 nm, which were highly correlated with the largest absorption by the second and first overtone of the C-H, O-H stretch vibrational transition, were caused by the deterioration of soybean oil.

• Journal of the Korea Concrete Institute
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• v.22 no.1
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• pp.85-91
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• 2010

In this study, the drying shrinkage strains were compared of 24~60 MPa concrete specimens subjected to various curing conditions and measurement methods were compared. And, the applicability of the test and prediction methods were investigated. According to the results, drying shrinkage was significantly reduced in 28 day curing condition. In the sealed curing case, drying shrinkage strain from demolding time was identical to the one of the standard curing case for low strength concrete, however, drying shrinkage strain was greatly increased than the standard case for high strength case because of the effect of autogenous shrinkage. The efficient measurement was possible using the embedded gage for concrete drying shrinkage, but, the measured value by contact gage was lower than the one by the embedded gage. The test results agreed with EC2 model better than the other.