• 한국지구물리탐사학회:학술대회논문집
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• 2009.05a
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• pp.57-65
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• 2009

Selection of good mineralized area is a combination of the integration of all the available geo-scientific (i.e., geological, geochemical, and geophysical) information, extrapolation of likely features from known mineralized terrenes and the ability to be predictive. The time-space relationships of the hydrothermal deposits in the East Asia are closely related to the changing plate motions. Also, two distinctive hydrothermal systems during Mesozoic occurred in Korea: the Jurassic/Early Cretaceous deep-level ones during the Daebo orogeny and the Late Cretaceous/Tertiary shallow geothermal ones during the Bulguksa event. Both the Mesozoic geothermal system and the mineralization document a close spatial and temporal relationship with syn- to post-tectonic magmatism. The Jurassic mineral deposits were formed at the relatively high temperature and deep-crustal level from the mineralizing fluids characterized by the relatively homogeneous and similar ranges of ${\delta}^{18}O$ values, suggesting that ore-forming fluids were principally derived from spatially associated Jurassic granitoid and related pegmatite. Most of the Jurassic auriferous deposits (ca. 165-145 Ma) show fluid characteristics typical of an orogenic-type gold deposits, and were probably generated in a compressional to transpressional regime caused by an orthogonal to oblique convergence of the Izanagi Plate into the East Asian continental margin. On the other hand, Late Cretaceous ferroalloy, base-metal and precious-metal deposits in the Taebaeksan, Okcheon and Gyeongsang basins occurred as vein, replacement, breccia-pipe, porphyry-style and skarn deposits. Diverse mineralization styles represent a spatial and temporal distinction between the proximal environment of sub-volcanic activity and the distal to transitional condition derived from volcanic environments. However, Cu (-Au) or Fe-Mo-W deposits are proximal to a magmatic source, whereas polymetallic or precious-metal deposits are more distal to transitional. Strike-slip faults and caldera-related fractures together with sub-volcanic activity are associated with major faults reactivated by a northward (oblique) to northwestward (orthogonal) convergence, and have played an important role in the formation of the Cretaceous Au-Ag lode deposits (ca. 110-45 Ma) under a continental arc setting. The temporal and spatial distinctions between the two typical Mesozoic deposit styles in Korea reflect a different thermal episodes (i.e., late orogenic and post-orogenic) and ore-forming fluids related to different depths of emplacement of magma (i.e., plutonic and sub-volcanic) due to regional changes in tectonic settings.

• Food Science of Animal Resources
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• v.30 no.5
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• pp.703-716
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• 2010

It has recently been considered urgent to establish an accurate definition and scope of functional foods in the livestock industry in Korea. The tertiary function of food is gradually emphasized with various changes in conditions such as international competitive power enhancement of the whole world, including Korea. Therefore, the purpose of this study was carried out to gather basic information toward the establishment of standardization, management plans, and a system adapted to the Korean state through researching management systems of functional meat and meat products in the European Union (EU) and the Oceania Area (OA). A brief summary of this study is as follows. In the EU and OA, special management systems and laws about functional livestock and products were once nonexistent; only 'nutrition claims' and 'health claims' operated in the nutritional consolidation side of foods. Also, it was once thought that functional index materials and permissions established in the application of functional products sufficed, because management standards for enriched food were not established. Therefore, standardization of functional live stock products needs to be considered based on the case of developed countries in the EU and OA. It also seems that the above functional indicative substances can be applied, based on normal standards of indicative substances of functional products and the normal standards of indicators of functional substances added to livestock products presented in this study.

• BMB Reports
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• v.31 no.6
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• pp.595-599
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• 1998

To investigate conformational information of a low oxygen affinity recombinant hemoglobin (rHb) containing $96Val{\rightarrow}Trp$ mutation at the ${\alpha}96$ position, we ave produced rHb (${\alpha}96Val{\rightarrow}Phe$) and rHb (${\alpha}96Val{\rightarrow}Tyr$), using the Escherichia coli expression system and site-directed mutagenesis. The oxygen affinity of rHb (${\alpha}96Val{\rightarrow}Phe$) is similar to that of human normal adult hemoglobin (Hb A). However, the oxygen affinity of rHb (${\alpha}96Val{\rightarrow}Tyr$) showed much lower oxygen affinity than Hb A which is similar to that of rHb (${\alpha}96Val{\rightarrow}Tyr$), providing an opportunity as a potential candidate for a hemoglobin-based blood substitute. Both rHb (${\alpha}96Val{\rightarrow}Phe$) and rHb (${\alpha}96Val{\rightarrow}Tyr)$ showed high cooperativity in oxygen binding. IH-NMR spectroscopy shows that both rHb (${\alpha}96Val{\rightarrow}Phe$) and rHb (${\alpha}96Val{\rightarrow}Tyr$) have very similar tertiary structure around the heme pockets and uaternary structure in the ${\alpha}_1/{\beta}_2$ subunit interface ompared to Hb A. The low oxygen affinity of rHb (${\alpha}96Val{\rightarrow}Tyr$) has been suggested to be due to a hydrogen bond caused by an extra hydroxyl group not present in rHb (${\alpha}96Val{\rightarrow}Phe$). However, investigation of the carbonmonoxy form of rHb (${\alpha}96Val{\rightarrow}Phe$) and (${\alpha}96Val{\rightarrow}Try$) in the presence of inositol hexaphosphate at low temperature suggests that low oxygen affinity of (${\alpha}96Val{\rightarrow}Try$) may arise from a mechanism different to that of rHb (${\alpha}96Val{\rightarrow}Trp$).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.10
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• pp.354-362
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• 2017

Due to population aging and westernized lifestyle, ischemic heart diseases are increasing, and Korea has one of the highest lengths of stay for ischemic heart diseases. Since the increase in the length of stay is a major cause of the increase in medical expenses, it is necessary to prepare a plan to manage the length of stay. Accordingly, this study was conducted to identify the factors influencing the length of stay of ischemic heart disease, and provide the elementary resources necessary for the management of the length of stay. The study subjects were 566 ischemic heart disease patients of a tertiary hospital. As the result of the study, first, the number of inpatients with chest pain as the chief complaint was the largest. Second, the average length of stay was 4.89 days, and the length of stay varied depending on the type of ischemic heart disease. Third, the age of over 75 years, diabetes, and dyspnea were the factors increasing the length of stay. Therefore, for management of adequate length of stay for ischemic heart disease, it is important to prevent the progression of illness through blood sugar control for ischemic heart disease patients with diabetes. Also, it is necessary to prepare a system where patients can visit hospitals as fast as possible if they have any symptoms.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.2
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• pp.120-131
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• 2011

A pilot-scale experiment of floodplain filtration with a filtration depth of 3.6m was performed employing flood/rest type raw-water supply system in an effort to find ways to improve river water quality by additional treatments of discharged effluent from sewage treatment plant. Soil samples were taken from 3 sites including Gumi, Daegu and Gimhae along the Nakdong river. Reductions of infiltration rates following increases in operating time was investigated in each soil sample, along with the analysis of removal efficiencies of various pollutants according to different depths and infiltration rates. The results show incremental development of clogging on the soil surface with increases in operation time, and illustrate exponential decrease in the infiltration rate. The time required for the removal of the clog from the soil surface was longer than 2 weeks for all soil samples analyzed. The stable infiltration rates for soils were 5 m/day for Gumi and for Daegu and Gimhae was 1 m/day. In unsaturated soils dissolved oxygen levels increased following the increase of filtration depth, suggesting that alternating application of flood and rest for raw-water supply effectively keeps the soil environment aerobic. For all soils, the nature of pollutant removal depending on the depth of filtration remained the same regardless of the infiltration rate. Most of the BOD and turbidity were removed within 1.2 m, about 30% of COD was removed within 3.6m and was expected to be removed further with increases in filtration depth. Nitrification occurred near the surface of all soils; however there was no significant removal of nitrogen in the filtration depths tested in this study. Although removal rate of phosphorus was low for Gumi's soil, it was high enough for other soils, suggesting that the method developed in this study could significantly improve river water quality.

• Economic and Environmental Geology
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• v.51 no.3
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• pp.233-248
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• 2018

Strata of the Central sub-basin in the Gunsan Basin, offshore, western Korea were analyzed by using integrated stratigraphy approach. As a result, five distinct unconformity-bounded units are recognized in the basin: Sequence I (Cretaceous or older(?)), Sequence II (Late Cretaceous), Sequence III (late Late Cretaceous or younger(?)), Sequence IV (Early Miocene or older(?)), Sequence V (Middle Miocene). Since the late Late Jurassic, along the Tan-Lu fault system wrench faults were developed and caused a series of small-scale strike-slip extensional basins. The sinistral movement of wrench faults continued until the Late Cretaceous forming a large-scale pull-apart basin. However, in the Early Tertiary, the orogenic event, called the Himalayan Orogeny, caused basin to be modified. From Late Eocene to Early Miocene, tectonic inversion accompanied by NW strike folds occurred in the East China. Therefore, the late Eocene to Oligocene was the main period of severe tectonic modification of the basin and Oligocene formation is hiatus. The rate of tectonic movements in Gunsan Basin slowed considerably. In that case, thermal subsidence up to the present has maintained with marine transgressions, which enable this area to change into the land part of the present basin.

• Quality Improvement in Health Care
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• v.9 no.2
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• pp.210-228
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• 2002

Background: The purpose of this research was to examine the fall incidence rate and its related factors of fall in inpatients. Methods: The data were collected from the 138 fall incident reports in one tertiary hospital in Seoul from April 1st 1999 to September 30th 2001. The Fall Incident Report Form was originally developed based on that of Massachusetts General Hospital revised in 1995. And this was modified for this survey by the collaborating work of QI team including researcher and department of nursing service of this particular hospital. The contents of Fall Incident Form were general characteristics of patient. factors related to fall. types and places of fall. circumstances, nursing interventions. and outcome. Results: 1) The incidence rate of fall was 0.08% of total discharged patients and 0.081 per 1000 patient-day. This incidence rate is much lower than that of several hospitals in USA. This finding might result from the different incidence report system of each hospital. 2) The characteristics of fall-prone patient were found as follows. They were mostly over 60 years old, in alert mental status, ambulatory with some assistance, and dependent on ambulatory device. The types of diseases related high incidence rate were cerebrovascular disease(3.2), hypertension(1.6), cardiovascular disease(1.4), diabetes(1.3) and liver disease(0.6). 3) The majority of fall events usually occurred m bed. bedside(walking or standing) and bathroom in patient room. Usually they were up on their own when they fell. And there were more falls of elderly occurred during night time than day or evening. 4) 63.8% of fall events resulted in physical injuries such as fracture and usually the patients had diagnostic procedures and some treatment(ex. suture) which caused additional cost to the patients and their families. 5) The found risk factors of fall were drugs(antihypertensive drug, diuretics) and environmental factors like too high bed height, long distance of bedside table and lamp switch, and slippery tile of bathroom floor. Conclusion: Considering these results, every medical and nursing staff should be aware of the risk factors of patients in hospital, and should intervene more actively the preventive managements, specially for the elderly patients during night. Therefore, it is recommended that the development of Fall Prevention Programs based on these results.

• The Journal of Korean Academy of Prosthodontics
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• v.44 no.2
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• pp.165-173
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• 2006

Purpose: With gold electroforming system fir the double crown, the secondary crown is electroformed directly onto the primary crown. An even thick layer of high precision can be acquired. It is thought that the retention of electroformed outer crown is primarily acquired by the adhesive force (surface tension) through the saliva which is interposed between precisely fitted inner and outer crown. The purpose of this study was to investigate the effect of taper and surface area of inner crown on the retentive force of electroformed outer crown according to the presence of saliva. Materials and methods: 32 titanium inner crowns with cervical diameter of 8 mm and cone angles of 0, 2, 4, 6 degrees, which had same surface area by regulated height, were machined on a lathe. Another 32 titanium inner crowns with cone angles of 0, 2, 4, 6 degrees, which had doubled surface area by increased cervical diameter. were fabricated. Eight specimens of each group, for a total of 64 titanium inner crowns, were prepared. The electroformed outer crowns were fabricated directly on the inner crowns by using electroforming machine(GAMMAT free, Gramm Technik, Germany). The tertiary frameworks were waxed-up on the electroformed outer crown and cast using nonprecious alloy($Rexillium^(R)III,\;Jeneric^(R)/Pentronh^(R)$ Inc., USA). The cast metal frameworks were sandblasted with alubimium oxides and cemented using resin cement(Superbond C&B, Sun Medical Co., Japan) over the electroformed copings of each specimen. Then, artificial saliva($Taliva^(R)$, Halim Pharm. Co., Korea) was sprayed between the inner and outer crown, and they were connected under 5 kg force. The retentive force was measured by the universal testing machine(Tinius Olsen 1000, Tinius Olsen, USA) with a cross-head speed of 66.67 mm/sec. The direction of cross-head travel was exactly aligned with the path of removal of the respective specimens. This measurement procedures for retentive force of electroformed outer crown with artificial saliva were repeated in the same way without presence of artificial saliva. Results and Conclusion: The following conclusions were drawn: 1. The retentive force of electroformed outer crown was decreased according to increased taper of inner crown(P<.05). 2. The retentive force of electroformed outer crown showed no significant differences according to surface area and the presence of artificial saliva(P>.05).

• Korea Journal of Hospital Management
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• v.7 no.4
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• pp.1-23
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• 2002

This study examined the influence of the separation of prescribing and dispensing roles(SPD) policy implemented in Korea in July 2000, especially on the change in the net profit of medical institutions. Using the data set from the Korea's National Health Insurance and the previous research, this study elicited the following main results. First, tertiary care institutions was estimated to lose about 631 billion won after the SPD policy. Second, general hospitals and hospitals gained about 557 billion and 564 billion won, respectively. Third, it is shown that clinics also gained 389-659 billion won. Finally, however, the change in net profit of medical institutions after the SPD policy largely depends on different estimation models. Moreover, it also varies from the assumptions on the price differential of a reimbursable drug which worked as cross-subsidy to insufficient physician's fee before the SPD policy. Despite such limitations as lack of data outside of the National Health Insurance's coverage, this study differs from others. This is the first research to explore the effect of the SPD policy on different types of medical institutions and to attempt to purely focus on the SPD policy. In this study, we can draw the policy implication that preparing for a policy change, the government should set up the policy evaluation system to collect the concerned data and develop the methodologies in advance to the policy implementation.

• Korea Journal of Hospital Management
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• v.19 no.1
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• pp.1-20
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• 2014

In this study, we investigated the relationship between friendship level within a hospital organization and job satisfaction, organizational commitment and job stress. Focusing on the hierarchy and occupation of a hospital, different from previous introductory studies. As a study tool, structured questionnaire were devised and used. The subjects were nurses, administrators and medical technicians who worked at 17 tertiary hospitals in Seoul and Kyongin area. To analyze the data, we conducted frequency analysis, t-test, one-way ANOVA, two-way ANOVA and multiple regression analysis.The main results of our study can be summarized as followings:Firstly, seen from the viewpoint of social demographic characteristics, on the whole friendship level with fellows is the highest, and then that with subordinates and that with bosses the lowest. Secondly, the friendship level with bosses, subordinates and fellows had a significant relationship with job satisfaction, organizational commitment and job stress, though there were some differences among them. In case of junior managers, the friendship level with fellows had a significant relationship with job satisfaction and organizational commitment; in case of middle managers, the friendship level with fellows had significant relationship with job satisfaction. We found that the friendship level with the bosses had a deeper relationship with job satisfaction, organizational commitment and job stress as we went down the hierarchy. Thirdly, analyzing the differences between occupation, administrators and medical technicians had relatively higher significant relationship with the friendship level with bosses than nurses in job satisfaction, organizational commitment and job stress. High friendship level with the bosses influenced job satisfaction significantly for the nurse; yet, in case of administrators and medical technicians, the friendship level with bosses influenced all of job satisfaction, organizational commitment and job stress. Based on our study, we recommend facilitating friendly relationship between the bosses and the subordinates in order to enhance job satisfaction, organizational commitment and job related stress reduction.